• An investigational anticancer agent that contains a thiophene moiety, 3-[(quinolin-4-ylmethyl)-amino]- N -[4-trifluoromethox)phenyl] thiophene-2-carboxamide (OSI-930), was tested to investigate its ability to modulate the activities of several cytochrome P450 enzymes. (aspetjournals.org)
  • However, it is the only amide anesthetic that contains a thiophene ring instead of a benzene ring, which accords it more liposolubility, resulting in high tissue penetration and diffusion 3-5 . (bvsalud.org)
  • The first synthesis of thiophene by Meyer, reported the same year that he made his discovery, involves acetylene and elemental sulfur. (wikipedia.org)
  • Synthesis of Thiophene/Furan-Artemisinin. (ogu.edu.tr)
  • Under a light-limited current of 20 nA, representative of operation of Si MWs under 1 Sun illumination conditions, the iR loss of thiophene-n-Si MW/PEDOT-PSS contacts was 20 mV, representing an order of magnitude reduction compared with PEDOT-PSS junctions formed with methyl terminated n-Si MWs. (caltech.edu)
  • Thiophene is a heterocyclic compound with the formula C4H4S. (wikipedia.org)
  • Thiophene is a five-membered heterocyclic compound containing a sulfur heteroatom with the molecular formula C4H4S. (chemenu.com)
  • Second, we demonstrate that additions of 0.5, 1.3 and 5.7 vol% thiophene (C4H4S) cause a 2×, 10×, and 20× reduction in the fouling factor after a 1400 min exposure. (canada.ca)
  • Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. (wikipedia.org)
  • Specialized thiophenes can be synthesized similarly using Lawesson's reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. (wikipedia.org)
  • Oxidation can occur both at sulfur, giving a thiophene S-oxide, as well as at the 2,3-double bond, giving the thiophene 2,3-epoxide, followed by subsequent NIH shift rearrangement. (wikipedia.org)
  • Modeling studies on the binding of OSI-930 to the active site of the P450 3A4 indicated that OSI-930 would be oriented properly in the active site for oxidation of the thiophene sulfur to give the sulfoxide, which has previously been shown to be a significant metabolite of OSI-930. (aspetjournals.org)
  • Thiophene was discovered as a contaminant in benzene. (wikipedia.org)
  • These reagents are contacted with an oxide catalyst at 500-550 °C. At room temperature, thiophene is a colorless liquid with a mildly pleasant odor reminiscent of benzene,[citation needed] with which thiophene shares some similarities. (wikipedia.org)
  • The high reactivity of thiophene toward sulfonation is the basis for the separation of thiophene from benzene, which are difficult to separate by distillation due to their similar boiling points (4 °C difference at ambient pressure). (wikipedia.org)
  • Like benzene, thiophene forms an azeotrope with ethanol. (wikipedia.org)
  • Thiophene is considered to be aromatic, although theoretical calculations suggest that the degree of aromaticity is less than that of benzene. (wikipedia.org)
  • Compounds analogous to thiophene include furan (C4H4O), selenophene (C4H4Se) and pyrrole (C4H4NH), which each vary by the heteroatom in the ring. (wikipedia.org)
  • Herein, novel thiophene/furan bridge artemisinin derivatives were synthesized by starting from artemisinin. (ogu.edu.tr)
  • This report is the second edition of the market research of disulfide oil, dimethyl disulphide (DMDS) and thiophene in Russia. (infomine.ru)
  • The purpose of the study was to analyze the market for disulfide oil, dimethyl disulphide and thiophene in Russia. (infomine.ru)
  • This research is devoted to the analysis of the market of disulfide oil, its substitute - dimethyl disulphide (DMDS) and thiophene in Russia. (infomine.ru)
  • In the fifth chapter of the report, potential areas of consumption of disulfide oil, substitutes (DMDS) and thiophene are considered. (infomine.ru)
  • We hypothesize that the tremendous fouling inhibition effect of the thiophene originates from its adsorption onto the sulfide surfaces, thereby blocking the dehydrogenation reactions. (canada.ca)
  • Thiophene derivatives have been detected at nanomole levels in 3.5 billions year old Martian soil sediments (Murray Formation, Pahrump Hills) by the rover Curiosity at Gale crater (Mars) between 2012 and 2017. (wikipedia.org)
  • The carrier mobility of poly(2,5-bis(3-alkylthiophen-2-yl) thieno[3,2-b]thiophene) semiconductors can be substantially enhanced after heating through a thermotropic mesophase transition, which causes a significant improvement in thin film structural order. (nist.gov)
  • Heating at high temperature (500° to 820 °C) of lacustrine mudstone samples by the Sample Analysis at Mars (SAM) instrument allowed gas chromatography-mass spectrometry (GC-MS) analyses of the evolved gases and the detection of aromatic and aliphatic molecules including several thiophene compounds. (wikipedia.org)
  • Tagetes species produce thiophenes, polyacetylenic compounds that possess strong biocidal activity, thus making Tagetes plants very useful for suppressing nematode populations in the soil and as sources of natural pesticides. (eurekamag.com)
  • Electrical measurements using a standard probe station indicated that the junction between individual thiophene-functionalized Si MWs and the conducting polymer poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate) (PEDOT:PSS) became more ohmic as more thiophene was added to the MW surface. (caltech.edu)
  • We obtained well-aligned films of poly[2,3-bis(3-octyloxyphenyl)quinoxaline-5,8-diyl-alt-thiophene-2,5-diyl] (TQ1) using the floating film transfer method. (lu.se)
  • Thiophene moieties have been attached to Si microwires (Si MWs) by a two-step chlorination/alkylation reaction method. (caltech.edu)
  • Thiophenes undergo hydrogenolysis to form hydrocarbons and hydrogen sulfide. (wikipedia.org)
  • the longest intramolecular distance between the two thiophene rings is 13.479 (4) Å for C4⋯C14 and the longest between the two tosyl rings is 9.983 (3) Å for C25⋯C29. (iucr.org)
  • The synthesis, electrochemical and spectroscopic properties of a series of thiophene-substituted 1,3-dithiole-2-ones is described. (soton.ac.uk)
  • Thiophene series_Product service_Changzhou Uchemi Pharmaceutical Technology Co., Ltd. (uchemi.cn)
  • Considering both thiophene concentrations and biomass yields, T. minuta and T. lucida appeared to be the most promising Tagetes species, with high potential for use as biocidal crops for the implementation of pest control practices that are less harmful to human health and natural resources. (eurekamag.com)
  • In the present study, Tagetes species (T. erecta, T. filifolia, T. lucida, T. minuta, T. patula and T. tenuifolia) grown in northern Italy were evaluated for their morphophenological parameters and thiophene pattern in different plant parts (roots, shoots and flowers). (eurekamag.com)
  • Such iR losses are much less than typical catalytic overpotentials for fuel formation, and hence the thiophene-functionalized Si MW contacts will not limit the performance of a Si MW array-based solar fuels device under 1 Sun illumination. (caltech.edu)
  • As a consequence of its aromaticity, thiophene does not exhibit the properties seen for conventional sulfides. (wikipedia.org)
  • Thiophene is produced on a modest scale of around 2,000 metric tons per year worldwide. (wikipedia.org)
  • This graph shows the total number of publications written about "Thiophenes" by people in this website by year, and whether "Thiophenes" was a major or minor topic of these publications. (ctsicn.org)
  • Thiophene enantiomers from the aerial parts of Eclipta prostrata . (bvsalud.org)
  • Tagetes lucida and T. tenuifolia possessed the highest amounts of total thiophenes (6717.3 and 6452.5 mg kg(-1) dry weight respectively), while T. minuta had the highest total thiophene yield (518.8 mg m(-2)), with BBT accounting for 98% of the total. (eurekamag.com)
  • Thiophene ring system has certain stability to oxidant. (chemenu.com)
  • In the first chapter the technology of production of disulphide oil, substitutes (DMDS) and thiophene is discussed in detail, potential sources of raw materials are listed. (infomine.ru)
  • It was clearly suggested by (i) the intramolecular cyclization of ketene N,S -acetals 7 to the corresponding thiophenes 8 , (ii) 1 H NMR studies of Meldrum's acid-substituted aminothioacetals 9 , and (iii) substitution studies of the methoxy group on Meldrum's acid containing N,S -acetals 9b . (beilstein-journals.org)
  • Projects for the production of thiophene have also been reviewed and its potential producer has been described. (infomine.ru)
  • Below are the most recent publications written about "Thiophenes" by people in Profiles. (ctsicn.org)