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  • give
  • We also know from our own customers, that several of our thioamides, which give rise to thiazoles, are being used in new oncology drugs, two of which are currently in Phase 3 ​" but could not give details for reasons of client confidentiality. (in-pharmatechnologist.com)
  • Aliphatic and aromatic nitriles react with thioacetic acid in the presence of calcium hydride to give the corresponding thioamides in good to excellent yields. (organic-chemistry.org)
  • The monosubstituted thioamide 16 reacted with 1a to give the unstable 4,5-dihydro-1H-pyrazole-3-carbothioamide 17. (uzh.ch)
  • preparation
  • In an environmentally friendly, atom-economical, and step-economical oxidation, thiols are used as a synthon for the preparation of thioamides without the use of exogenous sulfur reagents. (organic-chemistry.org)
  • This case report summarises the successful emergent control of thyrotoxicosis in the setting of thioamide-induced agranulocytosis complicated by sepsis, and demonstrates the safe use of multi-modal pharmacological therapies in preparation for total thyroidectomy. (bioscientifica.com)
  • simple
  • A simple workup protocol allows the isolation of synthetically valuable thioamide building blocks in good yield and purity. (organic-chemistry.org)
  • In the first part, reductions performed in alcoholic media are examined, where it is found that amino acid-derived hydroxamic acids and thioamides, respectively, are simple and versatile ligands that in combination with [RhCp*Cl 2 ] 2 efficiently catalyze this particular transformation. (diva-portal.org)
  • form
  • These results could be explained by the postulated metabolic pathways where thiazoles would undergo microsomal epoxidation of the C = C double bond and, after being hydrolyzed, the resulting epoxide would then be decomposed to form the corresponding thioamides and alpha-dicarbonyl fragments. (aspetjournals.org)
  • Intramolecular dehydrogenative C-S bond coupling of thioamides to form 1,3-benzothiazines under metal-free conditions. (bioportfolio.com)