Therefore common disease susceptibility. Medical search. Frequent questions

Common genetic variation influences susceptibility to Alzheimer's disease and age-related cognitive decline,' said Shulman. (alz.org)

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. (ox.ac.uk)
Several single-nucleotide polymorphisms (SNPs) in candidate genes have been associated with disease risk, including F5 rs6025, F2 rs1799963, FGG rs2066865, and ABO genetic variants. (medscape.com)
The current research is aimed at assessing the correlation between two functional GAS5 variants (rs145204276 and rs55829688) and susceptibility to IS in a Han Chinese population. (hindawi.com)
Variants in the GAS5 promoter region have been reported to be linked to mutiple diseases. (hindawi.com)
By examining the relationship between the genetic variants and childhood growth, he has found evidence that increased birthweight is associated with tumor extension, higher tumor stage, and metastatic disease. (alexslemonade.org)
Genome-wide association studies (GWAS) are widely used to identify susceptibility variants of common diseases. (springer.com)
The group looked into whether the gene variants known to be associated with those diseases were also present in people with PFAPA syndrome by comparing patients with the disorder from European-American and Turkish ancestries with the general U.S. population. (genome.gov)

We have tested the hypothesis that there is a common susceptibility for the development of COPD and facial wrinkling in cigarette smokers. (bmj.com)
The objective of our study was to test the hypothesis that there is a common susceptibility for the development of airflow obstruction and facial wrinkling in cigarette smokers. (bmj.com)
This proposal tests the paradigm-shifting hypothesis that mitochondrial-derived proteins (MPDs) play a previously unappreciated role in the regulation of cellular and organismal function, and that disregulation of MDPs is important in disease development. (nih.gov)

Human disease is only associated with the West African isolates. (bl.uk)
Lassa virus produces a fatal haemorrhagic disease while Mopeia isolates produce only an asymptomatic infection. (bl.uk)
This prospective study determined the antibiotic susceptibility of 131 isolates of Escherichia coli from the urine culture of 665 patients. (scialert.net)

Polygenic Scores (PSs) describe the genetic component of an individual's quantitative phenotype or their susceptibility to diseases with a genetic basis. (nature.com)
The common methionine/valine polymorphism at residue 129 in the PrP influences disease susceptibility and phenotype. (rcsb.org)

BACKGROUND AND PURPOSE:Ischemic stroke (IS) and coronary artery disease (CAD) share several risk factors and each has a substantial heritability. (ox.ac.uk)
Despite being a relatively common disease, the precise molecular mechanisms for the onset of ischemic stroke (IS) are still incompletely understood, with both environmental and genetic factors being implicated in this disease in a complex manner. (hindawi.com)

A common CTLA4 polymorphism confers susceptibility to autoimmune thyroid disease in celiac children. (unicampania.it)
In particular, the CTLA4 CT60 A/G dimorphism has been associated with Celiac Disease (CD) and was reported to be strongly associated with Autoimmune Thyroid Disease (AITD). (unicampania.it)
It is now recognized as an autoimmune thyroid disease and is characterized by high titers of circulating antibodies to thyroid peroxidase and thyroglobulin. (cap.org)

Participants examined scientific, ethical and logistical aspects of personalized population screening for prostate and breast cancer based on polygenic susceptibility. (cdc.gov)

In addition, a number of different genetic determinants of IS risk have been identified in genome-wide association studies, with single-nucleotide polymorphisms (SNPs) in 9p21, PITX2, HDAC9, ABO, NINJ2, ALDH2, and TSPAN2, all being linked with stroke susceptibility [ 2 ]. (hindawi.com)
These SNPs, however, are still thought to account for less than half of all genetic susceptibility to IS, with a number of yet to be discovered genes also contributing to the development of IS. (hindawi.com)
Commonly, single nucleotide polymorphisms (SNPs) are genotyped across the whole genome in different individuals, and statistical methods are used to detect the associations between SNPs and disease status. (springer.com)

IBD is genetically determined and many common risk alleles have been identified. (elifesciences.org)
INTRODUCTION: More than 70 common alleles are known to be involved in breast cancer (BC) susceptibility, and several exhibit significant heterogeneity in their associations with different BC subtypes. (lu.se)
Although there are differences in the association patterns between BRCA1 and BRCA2 mutation carriers and the general population for several loci, no study has comprehensively evaluated the associations of all known BC susceptibility alleles with risk of BC subtypes in BRCA1 and BRCA2 carriers. (lu.se)
CONCLUSIONS: Differences in associations of common BC susceptibility alleles between BRCA1 and BRCA2 carriers and the general population are explained to a large extent by differences in the prevalence of ER-positive and ER-negative tumors. (lu.se)

Aims This study aimed to investigate the possible influences of the CTLA4 CT60 A/G polymorphism in the susceptibility of Italian children to CD and in the predisposition to develop AITD in children with CD. (unicampania.it)

2=susceptible, clinical disease common at high parasite doses, but greater resistance to disease at low doses. (wikipedia.org)
3=highly susceptible, clinical disease common. (wikipedia.org)
Protection of susceptible individuals from communicable diseases by administration of a living modified agent ( e.g., yellow fever vaccine), a suspension of killed organisms ( e.g., pertussis vaccine), or an inactivated toxin ( e.g., tetanus). (theodora.com)
Lizards in northern Sweden were not only more susceptible to the disease but were also more health compromised once infected, with relatively more reduced growth rate and increased mortality than lizards from the south. (lu.se)

Acid reflux, more accurately known as gastroesophageal reflux disease, is a condition in which stoma. (home-remedies-for-you.com)
OBJECTIVES: Risk factors for Barrett's esophagus include gastroesophageal reflux disease (GERD) symptoms, age, abdominal obesity, and tobacco use. (who.int)

To date, these approaches have only identified two loci (PPARG, KCNJ11) robustly implicated in T2D susceptibility. (nih.gov)
This number includes six loci identified initially through the analysis of quantitative glycaemic phenotypes, illustrating the usefulness of this approach both to identify new disease genes and gain insight into the mechanisms leading to disease. (nih.gov)
Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers. (akcchf.org)

We conducted a genome-wide analysis to evaluate the extent of shared genetic determination of the two diseases. (ox.ac.uk)
METHODS:Genome-wide association data were obtained from the METASTROKE, Coronary Artery Disease Genome-wide Replication and Meta-analysis (CARDIoGRAM), and Coronary Artery Disease (C4D) Genetics consortia. (ox.ac.uk)
We demonstrate partial PS to be a proxy for the total PS and that a portion of the genome is enough to improve susceptibility predictions for the traits we test. (nature.com)
In this review we define the field of occupational and environmental health (OEH) research as the study of interactions between the following domains: environment (the exposome), 4 individual (genetic) susceptibility (the (epi)genome), and biological outcomes (the responsome) 5 ( figure 1 ). (bmj.com)

Venous thromboembolism (VTE) is a multifactorial disease driven by environmental/acquired risk factors such as age, obesity, oral contraceptives, and immobility, as well as inherited risk factors such as genetic polymorphisms. (medscape.com)
Susceptibility to venous thromboembolism is very complex. (medscape.com)
OBJECTIVES: Venous thromboembolism (VTE) is a common worldwide disease. (lu.se)

The disease in man and monkeys following infection with Lassa virus was similar. (bl.uk)
Urinary tract infection is a very common disease that can affect anyone at any age where the infection rate is higher in woman than man. (scialert.net)
In this paper, we report patterns of infection of a viral eye disease in juvenile Swedish common lizards (Lacerta vivipara). (lu.se)
Egyptian mummies showed evidence of trachoma infection one to two centuries before the common era. (aao.org)
We know that pregnant women are a population who may be at increased risk of susceptibility to infection, severe illness and mortality associated with other respiratory infections. (cdc.gov)
Overcrowded living conditions and day care center attendance predispose to infection, as do immunodeficiency states, asplenia, and sickle cell disease. (msdmanuals.com)
Treatment of Haemophilus infections depends on nature and location of the infection, but, for invasive disease, beta-lactam/beta-lactamase inhibitors, fluoroquinolones, and 2nd- and 3rd-generation cephalosporins are used. (msdmanuals.com)

Mar. 18, 2022 Alzheimer's disease is the most common and best known of the tauopathies, a set of neurodegenerative brain diseases caused by toxic tangles of the protein tau. (sciencedaily.com)

Stress factors and poor welfare can lead to increased susceptibility to transmissible Capable of being passed between individuals in the same species, as well as between different species (e.g. from animals to humans). (europa.eu)
The narrow and archaic vaccine-only paradigm to treat infectious diseases has left human populations vulnerable to a highly transmissible and potentially pathogenic virus with no approved drugs or vaccines in place. (thenhf.com)

Cigarette smoking causes accelerated facial wrinkling and predisposes to chronic obstructive pulmonary disease (COPD). (bmj.com)
2, 5 Smoking is also the major risk factor for the development of chronic obstructive pulmonary disease (COPD). (bmj.com)
Lung cancer and obstructive pulmonary disease share multiple etiological factors, such as cigarette smoking, occupational inhalation hazards, and air pollution, and 50-70% of lung cancer patients present with co-existing COPD or airflow obstruction 6 . (nature.com)
A better understanding of how these novel basal cells communicate with adjacent cells will help define disease mechanisms and suggest new diagnostic and therapeutic strategies for male infertility, and diseases of the lung, including asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). (nih.gov)

Considering previous reports indicating that rare mutations of TERT are found in patients with familial IPF, we suggest that the common genetic variation within TERT may contribute to the risk of sporadic IFP in the Japanese population. (bmj.com)
Our aim was to determine any association between multimorbidity and VTE and any possible shared familial susceptibility. (lu.se)
Familial associations suggest a weak shared familial susceptibility. (lu.se)

Here we describe the isolation, molecular typing, and antibiotic susceptibility testing of the causative agent of a rare case of generalized mycobacteriosis in a crossbred dog. (frontiersin.org)
Our aims were (1) to isolate and molecular type the causative agent, and (2) to determine antibiotic susceptibility in vitro so as to ensure the most appropriate antimicrobial therapy for the dog. (frontiersin.org)

Disentangling the role of pulmonary impairment in lung cancer development is important from an etiological perspective, for refining disease susceptibility mechanisms, and for informing precision prevention and risk stratification strategies. (nature.com)

Identify reasons why children have unique and varying age-related susceptibilities to toxicants. (cdc.gov)
Shulman's research is designed to identify genes that influence risk for Alzheimer's disease. (alz.org)
By leveraging a large multi-ethnic patient population drawn from the California Birth Cohort, we will compare the genomes of 545 children with osteosarcoma to the genomes of 3545 cancer-free individuals to identify genetic risk factors underlying this disease. (alexslemonade.org)

Centers for Disease Control and Prevention. (cdc.gov)
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
I'm Commander Ibad Khan and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
[ 18 ] The importance of obtaining a family history, a simple and frequently underutilized tool available to all clinicians, has been stressed by the Office of Genomics and Disease Prevention at the Centers for Disease Control and Prevention (CDC). (medscape.com)

The American Academy of Neurology (AAN) Foundation and the Alzheimer's Association awarded the 2009 Robert Katzman, M.D., Clinical Research Training Fellowship to Joshua Shulman, M.D., Ph.D., a senior neurology resident at the Brigham and Women's Hospital and the Massachusetts General Hospital, for his work investigating genes that influence risk for Alzheimer's disease. (alz.org)
Dr. Kyle Walsh, of Duke University, had a theory that the genes that determine height might have something to do with the development of osteosarcoma, the most common type of childhood bone cancer. (alexslemonade.org)
To see which genes (if any) were involved in the disease, Dr. Manthiram and her team searched for commonalities in symptoms between PFAPA syndrome and two other inflammatory diseases: Behçet's disease, which causes inflammation of blood vessels, and canker sores. (genome.gov)
They performed more detailed analyses of six genes that are strongly linked to Behçet's disease and canker sores. (genome.gov)
Although linkage and small-scale candidate gene studies were highly successful in the identification of genes, which, when mutated, caused monogenic forms of T2D, they were largely unsuccessful when applied to the more common forms of the disease. (nih.gov)
Ultimately, understanding of the disease biology, which will lead to identification of target genes for prevention, early detection and novel treatments of this malignancy. (akcchf.org)
However, there are many more genes with smaller disease risk that could account for much larger proportion of breast cancer. (cdc.gov)

Most of the common orthopaedic diseases seen in small animal practice today are considered multifactorial in origin, with physical conformation and genetics being predisposing factors. (biomedcentral.com)
Summarize this content to 30 words Unleashing the Potential of Hydrogen Water and Inhalation: A Natural Solution for the Three HighsfalseIn Malaysia, as in many parts of the world, health concerns like high blood pressure, elevated glucose levels, and increased cholesterol are becoming more common due to lifestyle, diet, genetics, and awareness. (thailand-business-news.com)
Our interpopulation comparison provides additional support for a link between genetics and disease resistance. (lu.se)

ABSTRACT This is the largest Libyan study to date to investigate the prevalence and antimicrobial susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) among health care workers in Tripoli, Libya. (who.int)

High Blood Pressure (Hypertension)High blood pressure strains the heart and blood vessels, increasing the risk of heart disease, stroke, and other cardiovascular problems. (thailand-business-news.com)
High Blood Cholesterol (Hypercholesterolemia)Elevated cholesterol levels raises the risk of heart disease by causing arterial plaque buildup. (thailand-business-news.com)
Scientists funded by the Lupus Research Alliance may have discovered why patients with lupus are at risk for heart disease. (lupusresearch.org)
In the present COVID-19 coronavirus epidemic the zinc + ionophore combination could have been employed in a targeted fashion for high-risk groups (elderly, diabetics, smokers, alcohol abusers, immune suppressant and illicit-drug users) as prevention and for curative purposes among patients with severe lung disease. (thenhf.com)
Its main purpose is early detection and treatment of asymptomatic disease, or risk assessment and prevention of future disease, in order to improve health outcomes in individuals and populations. (cdc.gov)
Increased risk of heart disease. (newhopemedicalcenter.com)
No causative agents could be found that linked risk of disease to maternal/interfollicular transfer of pathogens. (lu.se)
Regarding risk factors, older adults and people of all ages with severe underlying health conditions such as heart disease, lung disease, and diabetes seem to be at higher risk of developing severe illness. (cdc.gov)
These changes may increase the risk of more severe disease in pregnant women compared with non- pregnant adults. (cdc.gov)
Background: Chronic conditions increase the risk of invasive pneumococcal diseases (IPD). (bvsalud.org)
Among high-risk comorbidity (n = 211), cancer (28%), HIV/AIDS (25.7%) and hematological diseases (24.5%) were the most frequent. (bvsalud.org)

Researchers evaluate quantitative magnetic susceptibility mapping in detecting quantifiable markers of Parkinson's disease progression. (news-medical.net)

Data collated by Beth MacConnell and Dick Vincent and used with permission of the Whirling Disease Initiative, which funded the study. (wikipedia.org)
This study aims to determine the icrobiology of the bile culture and antimicrobial susceptibility in patients with symptomatic gallstone disease in our setup. (nepjol.info)
This prospective study included patients admitted in surgery department with a diagnosis of symptomatic gallstone disease and subjected for laparoscopic or open cholecystectomy from 1st of October 2015 to 30thSeptember 2016. (nepjol.info)
A retrospective case-control study was conducted to estimate breed predisposition for common orthopaedic conditions in 12 popular dog breeds in Norway and Sweden. (biomedcentral.com)
It wouldn't be rocket science to try it to treat crohn's disease in a study, so it's odd there haven't been any so far. (crohnsforum.com)
There has been only one study that suggested the patients that were being treated with itraconazole for secondary fungi infections also had improvement in crohn' disease. (crohnsforum.com)
At lease one study has shown that IgG tests against S. cerevisiae are associated with intestinal presence of Malassezia, specifically M. restricta, correlating with disease activity in crohn's disease. (crohnsforum.com)
I think these findings have implications for therapies aiming at stopping the spread of tau and thereby halting the disease progression in Alzheimer's," says Oskar Hansson, professor of neurology at Lund University and co-lead investigator of the study. (sciencedaily.com)
He continues to incorporate genetic data into his study to gain more specific understanding of osteosarcoma, the third most common cancer in adolescents. (alexslemonade.org)
If an association between one specific SNP and a certain disease has been identified in the primary study and confirmed in the replication study, we usually treat this association as true positive with a high confidence. (springer.com)
This study investigates associations between different channels of protobacco media and susceptibility to smoking cigarettes, cigarette experimentation, and current tobacco use among US middle and high school students. (who.int)

Emerging Infectious Diseases , 29 (11), 2189-2197. (cdc.gov)
Emerging Infectious Diseases , 29 (11), 2198-2202. (cdc.gov)

Susceptibility as defined in laboratory or exposure to M. cerebralis at vulnerable life stages. (wikipedia.org)
How does toxic exposure cause children's disease? (cdc.gov)
Describe the exposure disease model. (cdc.gov)
Name common sources of toxic exposure to children. (cdc.gov)
The length of time disease organisms remain infectious outside the bird depends on inherent characteristics of the organism, ambient temperature, exposure to direct sunlight, and other factors. (ufl.edu)
The analyses examined exposure to tobacco use in different channels of protobacco media on smoking susceptibility, experimentation, and current tobacco use, accounting for perceived peer tobacco use. (who.int)

Inflammatory bowel disease (IBD) affects 1.5-3.0 million people in the United States. (elifesciences.org)
Not too long ago, IL-17 blockers which are used to treat other inflammatory diseases, were tried to treat to crohn's disease, with rather disastrous consequences, crohn's disease patients became much sicker on IL-17 blockers, even though IL-17 is highly elevated in crohn's disease tissue. (crohnsforum.com)
The findings were made possible by the realization of commonalities with other chronic inflammatory conditions that also involved sores on the body, including the common canker sore. (genome.gov)
Each year approximately 1 million women in the United States experience an episode of symptomatic pelvic inflammatory disease (PID) (*) (1,2). (cdc.gov)

A tendency to bruise easily, that is, increases susceptibility to injuries. (home-remedies-for-you.com)
Why lupus increases the susceptibility to heart disease has remained unanswered. (lupusresearch.org)

2. Protection against infectious disease. (theodora.com)
Instead, they wield unelected power as they mandate countermeasures such as indoor quarantine that will further deprive the sunlight-deprived masses in the northern hemisphere of the natural vitamin D needed to prevent this seasonal infectious disease. (thenhf.com)
Chloroquine received early push-back by political antagonists of the President of the United States who initially endorsed it, which was met with ridicule and scorn , even in scientific publications as well as from Anthony Fauci, director of the National Institute of Infectious Disease . (thenhf.com)
A pandemic is an epidemic of an infectious disease that has spread across a large region affecting a substantial number of people. (aao.org)
The earliest recorded pandemics go back to ancient Greece, but the earliest record of an infectious disease (which had ophthalmic findings) was found in Australia and was probably trachoma. (aao.org)

A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as multiple sclerosis, restless legs syndrome, Alzheimer's disease, narcolepsy, and stroke. (alz.org)

The Robert Katzman, M.D., Clinical Research Training Fellowship is designed to encourage Alzheimer's disease clinical research with the goal of providing better treatment, prevention or cure of the disease. (alz.org)
Speaking of the CDC, they define Public Health as "the science of protecting and improving the health of families and communities through promotion of healthy lifestyles, research for disease and injury prevention, as well as detection and control of infectious diseases. (elearners.com)
The prevention of disease in commercial aviaries requires an understanding of how disease organisms are spread. (ufl.edu)

Furthermore, reverse causality remains a concern since pulmonary symptoms may be early manifestations of lung cancer or acquired lung diseases in patients whose immune system has already been compromised by undiagnosed cancer. (nature.com)

Information regarding breed susceptibility in different orthopaedic disorders in dogs may aid in the development of preventive measures, as well as act as a guide for potential pet owners and a motivational measure for dog breeders. (biomedcentral.com)

Because of the nature of the disease, researchers have long thought that answers may lie in genomics. (genome.gov)
Bone mass can decrease without symptoms for a significant period of time before fracture occurs, and since fracture is the main clinical sign of the disease, many clinicians and researchers limit the definitions of osteoporosis to the presence of an atraumatic fracture. (cdc.gov)

1=partial resistance, clinical disease rare and develops only when exposed to very high parasite doses. (wikipedia.org)
In addition, a bird may be in the incubation stage of a disease and appear healthy, only after exposing all the birds in the aviary does the bird develop the clinical disease. (ufl.edu)

Your holiday gift today will provide much-needed care and support to the millions of families facing Alzheimer's, while advancing critical research to help end this disease. (alz.org)
Learn how Alzheimer's disease affects the brain. (alz.org)
Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer's disease. (sciencedaily.com)
The spread is restricted during normal aging, but in Alzheimer's disease the spread may be facilitated by beta-amyloid, and likely leads to widespread neuronal death and eventually dementia," says lead author Jacob Vogel from McGill University. (sciencedaily.com)
There are two proteins that are known to be linked to Alzheimer's disease -- beta-amyloid, which forms what is known as a plaque in the brain, and tau, which forms tangles within brain cells. (sciencedaily.com)
Our findings have implications for understanding the disease, but more importantly for the development of therapies against Alzheimer's, which are directed against either beta-amyloid or tau. (sciencedaily.com)
Mar. 3, 2020 The toxic protein tau is a key biological feature in the brains of people with Alzheimer's disease. (sciencedaily.com)
Feb. 6, 2020 The protein tau has long been implicated in Alzheimer's and a host of other debilitating brain diseases. (sciencedaily.com)

MAIN OUTCOMES AND MEASURES: Multimorbidity was determined by a counting method using 45 non-communicable diseases. (lu.se)

Chagas disease is an infectious condition that is commonly transmitted through the feces of the redu. (home-remedies-for-you.com)
Another means of disease transmission commonly described is the airborne route. (ufl.edu)

This project aims to achieve a paradigm shift in antimicrobial drug discovery by finding next generation anti-infectives that prevent disease by blocking pathogen adaptation to host physiology. (nih.gov)
The results show that a major factor influencing offspring susceptibility is family identity, suggesting heritable variation in pathogen resistance. (lu.se)

MAC infections may cause granulomatous diseases, which range from localized granulomas to disseminated diseases. (frontiersin.org)
As far as itraconazole, it's a very common medication used to treat fungi infections. (crohnsforum.com)
Many people with crohn's disease on anti-TNF would have been prescribed itraconazole to deal with fungi infections. (crohnsforum.com)
They can develop intestinal manifestation of fungi infections that closely mimic crohn's disease, typical transmural inflammation with pockets of granuloma. (crohnsforum.com)
Microbes that cause disease are becoming resistant to antibiotics faster than we can find new ones, making many common infections untreatable and life threatening. (nih.gov)
This can pose risks to consumers, for example through common food-borne infections such as Salmonella , Campylobacter and E. coli . (europa.eu)
Over time, recurrent infections can lead to chronic lung disease. (medlineplus.gov)

Patients with motor neuron disease (MND) are generally free of cognitive impairment, but evidence is growing to support an association between MND and frontal lobe or frontotemporal dementia (FTD). (medscape.com)

Similar differences in host susceptibility have also been demonstrated. (bl.uk)

The occurrence of the disease was high in March-October. (scialert.net)
Multimorbidity was defined by the occurrence of ≥2 diseases. (lu.se)

Our research suggests that toxic tau may spread across different brain regions through direct neuronal connections, much like infectious diseases may spread to different cities through different transportation pathways. (sciencedaily.com)
A particularly high disease incidence of hemangiosarcoma in golden retriever suggests a genetic susceptibility. (akcchf.org)

While PFAPA syndrome has become the most common recurring fever syndrome in children from Western countries, diagnosis and treatment methods have remained largely primitive and insufficient. (genome.gov)

On the severity scale, canker sores would be on the mild end, Behçet's disease on the severe end, and PFAPA syndrome between the two. (genome.gov)
Aviaries in which birds are stressed experience severe losses when disease challenge occurs. (ufl.edu)

Dr. Kaplan and her colleagues suspected that immune system cells known as neutrophils are responsible for causing the artery injuries that lead to heart disease. (lupusresearch.org)

Smoking related COPD and facial wrinkling: is there a common susceptibility? (bmj.com)
Facial wrinkling is associated with COPD in smokers, and both disease processes may share a common susceptibility. (bmj.com)
Facial wrinkling in smokers may therefore be a biomarker of susceptibility to COPD. (bmj.com)
COPD is a heterogeneous syndrome of chronic bronchitis, small airways disease, and alveolar destruction (emphysema) that varies in proportion between affected individuals. (bmj.com)
It is well recognised that only a proportion of cigarette smokers develop COPD, 8, 9 and that this is likely to be the result of genetic susceptibility to the effects of cigarette smoke. (bmj.com)

In the context of breed susceptibility this may lead to an incorrect impression that some popular breeds are predisposed to conditions when in fact they are not. (biomedcentral.com)
In this context, biological outcomes can be defined as clinical diseases as well as relevant (preclinical) intermediate endpoints. (bmj.com)

When a disease challenge occurs, one needs to investigate the means of transmission described above to determine how the organism gained entrance. (ufl.edu)

Despite its importance in evolutionary biology, studies of the pattern of disease resistance in natural populations are rare. (lu.se)
article{c34f0f78-02b4-4f39-a3c2-3d18e368d937, abstract = {{Despite its importance in evolutionary biology, studies of the pattern of disease resistance in natural populations are rare. (lu.se)

In addition, such flocks typically have chronic problems with opportunist organisms (always present but only cause disease when birds' immune systems are not functioning properly) such as E. coli , Candida, and others. (ufl.edu)
Common variable immune deficiency (CVID) is a disorder that impairs the immune system. (medlineplus.gov)
Most recently, at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, Dr. Mariana Kaplan and colleagues found that abnormal immune system cells are damaging patients' arteries. (lupusresearch.org)

In addition, vaccines for diseases such as measles and influenza do not provide protection for people with CVID because they cannot produce an antibody response. (medlineplus.gov)

Specifically, the results suggest that therapies that limit uptake of tau into the neurons or transportation or excretion of tau, could limit disease progression," says Oskar Hansson. (sciencedaily.com)

These issues are closely linked to chronic diseases. (thailand-business-news.com)
Chronic diseases microbial-non-susceptibility of pneumococcus. (bvsalud.org)

Anatomy12

Organisms17

Diseases38

Chemicals and Drugs49

Analytical, Diagnostic and Therapeutic Techniques and Equipment45

Psychiatry and Psychology3

Phenomena and Processes78

Disciplines and Occupations8

Anthropology, Education, Sociology and Social Phenomena2

Information Science12

Named Groups5

Health Care30

Geographicals7

Influences Susceptibility1

Variants7

Hypothesis3

Isolates3

Phenotype2

Ischemic stroke2

Autoimmune thyroid3

Polygenic1

SNPs3

Alleles4

Polymorphism1

Susceptible4

Gastroesophageal reflux2

Loci3

Genome4

Venous3

Infection7

20221

Transmissible2

Obstructive pulmonary disease4

Familial3

Antibiotic2

Etiological1

Identify3

Centers5

Genes7

Genetics3

Prevalence1

Risk11

Parkinson's1

Study11

Emerging Infectio2

Exposure6

Inflammatory4

Increases2

Infectious disease5

Stroke1

Prevention3

Pulmonary1

Disorders1

Researchers2

Clinical disease2

Alzheimer's8

Communicable1

Commonly2

Pathogen2

Infections7

Cognitive1

Differences1

Occurrence2

Suggests2

METHODS1

Severe2

Injuries1

COPD5

Context2

Investigate1

Pattern2

Immune3

Vaccines1

Progression1

Chronic diseases2