Therapy for humans. Medical search. Frequent questions

Since pharmaceutical interest in this disease is low, two EU-supported projects (EURAMAN and HUE-MAN) within the 5th and 6th framework program, respectively have worked towards developing the recombinant human enzyme (rhLAMAN) as a therapeutic agent for patients suffering from alpha-Mannosidosis. (europa.eu)
In line with our plans we have been able to demonstrate the safety and clinical efficacy of rhLAMAN as an effective therapeutic agent for treatment of the human disease alpha-Mannosidosis in clinical trial Phases 1 and 2. (europa.eu)
To investigate the in vitro effects of suicide gene therapy system of herpes simplex virus thymidine kinase gene (HSV-TK) in combination with the treatment of nucleotide analog-ganciclovir (GCV) on human pancreatic cancer, and to provide a novel clinical therapeutic method for human pancreatic cancer. (wjgnet.com)
Once generated, we will use these rat models to assess the safety and therapeutic potential of cells derived from human pluripotent stem cells. (ca.gov)
In the study , researchers labeled ofatumumab, a recently developed anti-CD20 fully human antibody, with 177 Lu, a widely used therapeutic radioisotope that can kill cancer cells. (worldhealth.net)
They then determined the in vitro characteristics of [ 177 Lu]Lu-ofatumumab, estimated human dosimetry, and evaluated its therapeutic effectiveness for non-Hodgkin lymphoma in a mouse model. (worldhealth.net)
The excellent therapeutic results in this animal model of human B cell lymphoma suggest that this curative treatment should be tested in humans with non-Hodgkin lymphoma," noted Wahl. (worldhealth.net)
As a result, researchers will use gene therapy in which a harmless adeno-associated virus (AAV2) is modified to carry the BDNF gene and injected directly into targeted regions of the brain, where researchers hope it will prompt production of therapeutic BDNF in nearby cells. (universityofcalifornia.edu)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)

In September 1997, CDC convened a meeting of expert consultants who reviewed and considered background information about HIV-related TB in the United States and the scientific principles of therapy for both diseases (Part I of this report). (cdc.gov)
Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planetincurable with disturbing symptoms that include dementia, personality shifts, hallucinations and coordination problems. (infectioncontroltoday.com)
The goal of the Program in Human Gene Therapy is to develop gene transfer technologies and use them for hepatic gene therapy for the treatment of genetic and acquired diseases. (stanford.edu)
Gene therapy has been utilized successfully to repair or inactivate mutations in animal models of monogenic human diseases 19 as well as human in vitro cells 12 . (nature.com)
As stem cell-based therapies move towards clinical application, it is clear that more relevant animal models are required to demonstrate the safety and efficacy of stem cells for specific human diseases. (ca.gov)
Rats are the preferred animal model for many human diseases. (ca.gov)
We proposed to use the classical embryonic stem cell-based gene-targeting technology to generate rat models mimicking human heart failure, diabetes and neurodegenerative diseases. (ca.gov)
Rats have long been used as models that better replicate human physiology and pathophysiology than do mice and are the preferred model for the study of many human diseases. (ca.gov)
These diseases are characterized by the loss of specific cell types and can be treated and potentially cured with stem cell-based therapies. (ca.gov)
Our project will provide the research community with the tools and technology necessary to overcome the current constraints of mouse models and will serve as a better investigative platform for understanding the progression and treatment of human diseases. (ca.gov)
These diseases can be potentially improved or even cured by cell replacement-based therapies. (ca.gov)
Tuszynski said gene therapy, which debuted in 1980 and has been tested on multiple diseases and conditions, represents a different approach to a disease that requires new ways of thinking about the disease and new attempts at treatments. (universityofcalifornia.edu)
We hope to build on recent successes of gene therapy in other diseases, including a breakthrough success in the treatment of congenital weakness in infants (spinal muscular atrophy) and blindness (Leber Hereditary Optic Neuropathy, a form of retinitis pigmentosa)," Tuszynski said. (universityofcalifornia.edu)
Zehnder says: "These genetic pathways help us target the conserved genes that already exist in humans to generate novel targets and develop therapeutics to help overcome diseases that devastate human health. (ddw-online.com)
We are using machine learning (ML)techniques to analyse proprietary data from the world's most precise hibernator biobank, hundreds of additional datasets from more than 30 species and specific expertise in genomics, transcriptomics and physiology to identify disease resistance genes and develop drugs to treat human diseases," says Zehnder. (ddw-online.com)

These findings suggest that a lethal lung disease can be targeted and corrected in a human lung organoid model in vitro . (nature.com)
It showed favorable in vitro characteristics and dosimetry estimates that support the feasibility of human translation. (worldhealth.net)
This second-generation of CAR T targets an alternative surface marker called B cell activating factor receptor (BAFF-R). Scientists engineered CAR T cells to go after human lymphoma and acute lymphocytic leukemia cells expressing BAFF-R in vitro and in mouse models in comparison with CD19-directed CAR T cells. (ajmc.com)
The most remarkable decrease in viability was recognized in the combined therapy of laser hyperthermia and PDT among three types of therapies in vitro. (spie.org)
The combined therapy of laser hyperthermia and PDT has proven to be highly effective by in vivo and in vitro study using human pancreatic cancer cell line. (spie.org)

They are 3-dimensional, complex, multicellular structures that can be derived from patient specific human induced pluripotent stem cells (hiPSCs). (nature.com)
For example, expanding the scope of this guidance beyond human somatic cells to include cells derived from adult and pluripotent stem cells, would provide valuable insight to sponsors on FDA's current thinking. (bio.org)

The full report of the WFOT Human Resources Project 2022, presenting information on occupational therapy and occupational therapists globally, listed numerically. (wfot.org)
Kyuhwan Shim et al, Cure of Disseminated Human Lymphoma with [177Lu]Lu-Ofatumumab in a Preclinical Model, Journal of Nuclear Medicine (2022). (medicalxpress.com)

Treatment of human papillomavirus (HPV) infection is directed to the macroscopic (ie, genital warts) or pathologic (ie, precancerous) lesions caused by infection. (medscape.com)

These guidelines update previous CDC recommendations for the diagnosis, treatment, and prevention of tuberculosis (TB) among adults and children coinfected with human immunodeficiency virus (HIV) in the United States. (cdc.gov)
These guidelines update previous CDC recommendations for treating and preventing active tuberculosis (TB) among adults and children coinfected with human immunodeficiency virus (HIV) (1-3). (cdc.gov)

The most notable changes in these guidelines reflect both the findings of clinical trials that evaluated new drug regimens for treating and preventing TB among HIV-infected persons and recent advances in the use of antiretroviral therapy. (cdc.gov)
In September 1997, when CDC convened a meeting of expert consultants to discuss current information about HIV-related TB, special emphasis was given to issues related to coadministration of TB therapy and antiretroviral therapy and how to translate this information into management guidelines. (cdc.gov)
All HIV-infected patients undergoing treatment for TB should be evaluated for antiretroviral therapy, because most patients with HIV-related TB are candidates for concurrent administration of antituberculosis and antiretroviral drug therapies. (cdc.gov)
Physicians and patients also should be aware that paradoxical reactions might occur during the course of TB treatment when antiretroviral therapy restores immune function. (cdc.gov)
more detailed information about antiretroviral therapy is published elsewhere (4). (cdc.gov)
Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. (worldhealth.net)

Therefore, we performed a phase 1/2a, single-arm clinical trial to evaluate the safety and efficacy of human umbilical cord-derived MSCs (UMSCs) in the treatment of psoriasis and to preliminarily explore the possible mechanisms. (nature.com)
The main goal of this project is to develop rat models for assessing the safety and efficacy of human stem cell grafts. (ca.gov)

There is a 30% chance of relapsing with the 2 CAR T therapies on the market, Novartis' tisagenlecleucel, sold under the name Kymriah, and axicabtagene ciloleucel, or Yescarta, from Kite Pharma/Gilead. (ajmc.com)

Mice injected with human B cell lymphoma were either untreated, treated with unlabeled ofatumumab, treated with 8.51 MBq of [ 177 Lu]Lu-IgG, or treated with 0.74 MBq or 8.51 MBq of [ 177 Lu]Lu-ofatumumab. (worldhealth.net)
Mice treated with the other therapies or left untreated, on the other hand, continued to show tumor cells present," Wahl explained. (worldhealth.net)
Bioluminescence images of untreated and treated mice with human B cell lymphoma. (medicalxpress.com)
I have conducted laser hyperthermia, photodynamic therapy (PDT) and the combined therapy of laser hyperthermia and PDT for solid tumor of human pancreatic carcinoma transplanted to nude mice. (spie.org)
Necrosis amounted 100% of the total area in tumors of 3 out of 6 mice histopathologically 7 days after the therapy. (spie.org)

Unlike humans and other mammals, which become less fertile with age, naked mole-rats are able to reproduce throughout their long lifespans. (veterinarypracticenews.com)
Publishes scientific papers on original investigations into the transfer and expression of genes in mammals, including humans. (genetherapynet.com)
Comparative genomics is the process of using data from mammals and other species to show us where the most important genetic sequences lie and can help us better understand the genetic basis of human disease," says Ashley Zehnder CEO and co-founder of Fauna Bio. (ddw-online.com)
Fauna Bio's platform navigates to the genes responsible for these traits between mammals, including humans, to find the specific genes that can resist disease. (ddw-online.com)

Researchers said Wednesday they created a second-generation chimeric antigen receptor (CAR) T-cell therapy that prevented relapse of lymphoma and leukemia and led to 100% long-term survival in early laboratory studies. (ajmc.com)
If successful, it could ultimately be used as initial, frontline treatment and thereby change the face of leukemia and lymphoma therapy globally. (ajmc.com)

Our data demonstrate that HSV-TK/GCV suicide gene therapy system is effective for treating experimental human pancreatic cancer, which is largely resistant to the common therapies, so the suicide gene therapy system may be a potential treatment approach for pancreatic cancer. (wjgnet.com)
We investigated the use of human CD20 as suicide gene in T-lymphocytes. (haematologica.org)
Co-transfer of a suicide gene would provide a desirable safety switch in clinical TCR gene therapy. (haematologica.org)
Human CD20 has been proposed as non-immunogenic protein with a dual function as selection marker and suicide gene. (haematologica.org)
Although human CD20 has previously been described as functional selection marker and suicide gene after retroviral transfer to T lymphocytes, 9 , 10 the specificities of these T cells were unknown, and therefore a potential effect of CD20 on antigen-specific T-cell functions could not be investigated. (haematologica.org)

These results demonstrate that if antibiotic therapy had been indicated for infections with Sh. (nih.gov)
The work package focusing on molecular studies generated new evidence about the changes effected by antibiotic therapy on commensal organisms or opportunistic pathogens in the oropharyngeal, nasal and gastro-intestinal flora and study AMR mechanisms and the dissemination of successful clones of fluoroquinolone-resistant, carbapenem-resistant or extended-spectrum beta-lactamase harboring Gram-negative bacteria, MRSA and fluoroquinolone-resistant viridans streptococci. (europa.eu)

Although this chemotherapy with immunotherapy combination is usually initially effective, many patients don't respond or relapse, so we need improved therapies," said Richard L. Wahl, MD, the Elizabeth E. Mallinckrodt Professor and director of Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis, Missouri. (worldhealth.net)

Before human stem cells can be used in clinical trials, however, their safety and efficacy need to be tested in animal models. (ca.gov)
Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia. (universityofcalifornia.edu)
This is the first safety and efficacy assessment of AAV2-BDNF in humans. (universityofcalifornia.edu)

Within the clinical trials, the dose levels based on the results in the non-clinical tests, were confirmed and a minimum effective dose in humans established. (europa.eu)
Accordingly, the unique chemical and physical properties, potential applications in medical fields, as well as human biosafety in clinical trials are reviewed in this study. (cdc.gov)
Noise -induced hearing loss and its prevention: integration of data from animal models and human clinical trials. (cdc.gov)

Human HGF plasmid DNA therapy of cardiomyocytes is being examined as a potential treatment for coronary artery disease (a major cause of myocardial infarction (MI)), as well as treatment for the damage that occurs to the heart after MI. (wikipedia.org)
Ideally, the management of TB among HIV-infected patients taking antiretroviral drugs requires a) directly observed therapy, b) availability of experienced and coordinated TB/HIV care givers, and in most situations, c) use of a TB treatment regimen that includes rifabutin instead of rifampin. (cdc.gov)
Because alternatives to the use of rifampin for antituberculosis treatment are now available, the previously recommended practice of stopping protease inhibitor therapy to allow the use of rifampin for TB treatment is no longer recommended for patients with HIV-related TB. (cdc.gov)
The use of rifabutin-containing antituberculosis regimens should always include an assessment of the patient's response to treatment to decide the appropriate duration of therapy (i.e., 6 months or 9 months). (cdc.gov)
The revolutionary medical breakthrough of gene therapy is much more than the treatment of disease by altering human DNA -- it offers the intriguing possibility of creating "designer children. (closertotruth.com)
If testing is successful in humans, this would represent an excellent new treatment option for patients with this disease. (worldhealth.net)
That's why it is so important to treat the whole tinderbox area (this is also called field therapy or field treatment). (skincancer.org)
Note that not everyone is suitable for this treatment, and if you are experiencing any breathing difficulties, if you have any type of tumor or cancer, or if you are undergoing treatment for a serious health problem, you should be extremely cautious with HGH therapy. (hiboox.com)
Treatment protocols in human medicine vary from standard treatments such as avoiding known triggers, anticonvulsant medications, vagal nerve stimulation, and surgical resection of seizure foci to more holistic approaches including acupuncture, dietary adjustment, nutritional supplements, and reflexology. (ahvma.org)
Spinal manipulative therapy (SMT), or chiropractic adjustments, has also been suggested as possible adjunctive treatment for seizures in refractory human epileptics. (ahvma.org)
The purpose of this paper is to review the use of SMT as an adjunctive treatment for seizures in humans and to open the consideration of its use as a potential additional therapy for seizures in domestic animals. (ahvma.org)
Denial of access to such essential medicines - including abrupt 'weaning' to a zero dose for those receiving this treatment - defies the internationally accepted scientific consensus and is a fundamental breach of human rights, principally that of the right to the highest attainable standard of health. (idpc.net)
Denial of opiate substitution therapy has been described by the Special Rapporteur on torture and other cruel, inhuman or degrading treatment or punishment, Mr. Juan E. Méndez, as a 'particular form of illtreatment and possibly torture of drug users' (A/HRC/10/44 and Corr.1, para. (idpc.net)
This therapy caused 70-80% necrosis of the total area of pancreatic tumors after 7 days of the treatment. (spie.org)
In another example of CDC-funded work with a simpler human microbiome, Dr. Sam Brown's lab at Georgia Tech is examining the microbiota in the lungs of cystic fibrosis patients to better understand these microbial communities and subsequently tailor antibiotic treatment to the patient and their specificdisease state. (cdc.gov)
Regardless of the body site, individualized treatment strategies across human microbiomes may be able to enhance treatment effectiveness, improve antibiotic stewardship, and reduce resistance. (cdc.gov)

4) Generated a motor neuron reporter human embryonic stem cell line. (ca.gov)
Human pluripotent stem cell-derived dopamine neurons after transplantation into the brain of a Parkinsonian monkey. (sloankettering.edu)
To this end, we overexpressed key transcriptional regulators of astroglial development in human GBM and GBM stem cell lines. (lu.se)

All HIV-infected persons at risk for infection with M. tuberculosis must be carefully evaluated and, if indicated, administered therapy to prevent the progression of latent infection to active TB disease and avoid the complications associated with HIV-related TB. (cdc.gov)
Could gene therapy halt the progression of Alzheimer's disease? (universityofcalifornia.edu)

Photobiomodulation as an adjunctive therapy for alveolar socket preservation: a preliminary study in humans. (bvsalud.org)
Photobiomodulation (PBM) based on photochemical stimulation by low-intensity lasers emerges as an adjunctive therapy for alveolar socket preservation. (bvsalud.org)

To evaluate expression of proangiogenic matrix metalloproteinases (MMP) 2 and 9 at distinct intervals after verteporfin photodynamic therapy (PDT) in human choroidal neovascular membranes (CNV) secondary to age-related macular degeneration (AMD). (bmj.com)

Adding to CDC's current recommendations for administering isoniazid preventive therapy to HIV-infected persons with positive tuberculin skin tests and to HIV-infected persons who were exposed to patients with infectious TB, this report also describes in detail the use of new short-course (i.e., 2 months) multidrug regimens (e.g., a rifamycin, such as rifampin or rifabutin, combined with pyrazinamide) to prevent TB in persons with HIV infection. (cdc.gov)
If you're at high risk, ask your dermatologist about dosage and if this preventive therapy is right for you. (skincancer.org)

The most significant finding of the study came from the preclinical therapy trial. (worldhealth.net)

Following experimental therapies have begun 5-6 weeks after transplantation. (spie.org)

A new islet cell replacement therapy, with advantages over islet cell transplantation, has had an application to start human trials submitted to the US Food and Drug Administration (FDA). (diabetesdigest.com)
In addition, fecal microbiota transplantation (FMT), representing administration of feces, a live biotherapeutic, is increasingly applied in the management of multiply recurrent Clostridioides difficile infection (CDI), even as the function of the human microbiome in prevention of CDI is still studied. (cdc.gov)

If the causative agent had not crossed the species barrier, what then was the etiology of the human cases? (who.int)

A relationship between Westside Health Authority (WHA) and the Northwestern University Department of Physical Therapy & Human Movement Sciences started in 2004. (northwestern.edu)
This is important because if we can figure out how they're able to do this, we might be able to develop new drug targets or techniques to help human health," says lead author, Miguel Brieño-Enríquez, MD, PhD, assistant professor at Magee-Womens Research Institute and the University of Pittsburgh School of Medicine's Department of Obstetrics, Gynecology and Reproductive Sciences . (veterinarypracticenews.com)

While this in itself is a remarkable thought, the bigger potential the study aims to unlock is the ways in which the findings could impact the development of new human therapies. (veterinarypracticenews.com)
Trials in human participants are expected to begin within 6 months, according to one of the researchers involved in the study, which was published in Science Translational Medicine . (ajmc.com)
In this study, we investigated the use of CD20 as safety switch after retroviral transfer to T cells with different cytomegalovirus (CMV) specificities, and conclude that CD20 may be broadly applicable as safeguard in adoptive T-cell therapy. (haematologica.org)
A seminal book that placed the study of human behaviour in a new perspective, demolished many schools of psychology and brought about a return to the dynamic view of human personality. (whsmith.co.uk)
Our study aimed to evaluate the effects of PBM therapy on alveolar bone repair. (bvsalud.org)
Progress in understanding how the human microbiome can be leveraged for public health is exemplified in a recent CDC-funded study. (cdc.gov)

His laboratory studies the human immune response to infection for a wide variety of major human pathogens, including emerging infections. (hstalks.com)
This mechanism explains one potential reason for why HIV stays in human tissues forever," he said, adding that the research also shows the complexity of HIV infection. (worldhealth.net)
Epidemic myalgia in adults associated with human parechovirus type 3 infection, Yamagata, Japan, 2008. (cdc.gov)
Infant deaths associated with human parechovirus infection in Wisconsin. (cdc.gov)

We will use these models to assess human cellular therapies. (ca.gov)

Veterinary and Human Toxicology. (cdc.gov)

He is the Director of the Human Immunome Project, an ambitious effort to identify the sequence of all transcripts for human adaptive immune receptors. (hstalks.com)
But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system. (worldhealth.net)
rabies immune globulin, human (RIG) decreases effects of BCG vaccine live by Other (see comment). (medscape.com)
efgartigimod alfa will decrease the level or effect of rabies immune globulin, human (RIG) by receptor binding competition. (medscape.com)

Based on this open trial of dopamine agonist therapy in humans with neglect, larger controlled studies may be warranted. (nih.gov)
Based on those results, we are currently pursuing the development of a clinical-grade dopamine neuron cell product and are in the process of generating the data necessary for an IND (investigational new drug) application from the FDA, which is required for the first human clinical use of human ESC-derived dopamine neurons. (sloankettering.edu)

Final Report Summary - ALPHA-MAN (Clinical development of Enzyme Replacement Therapy in alpha-Mannosidosis patients using recombinant human enzyme. (europa.eu)
Today, the most promising therapy for lysosomal storage disorders including alpha-Mannosidosis is Enzyme Replacement Therapy (ERT) where the respective enzyme lacking in the patient is produced by recombinant approaches and then introduced into the blood stream, from where it is internalized by the cells and reaches the lysosomes replacing the missing endogenous enzyme. (europa.eu)

Includes ethical/legal/regulatory papers related directly to the area of gene transfer into humans. (genetherapynet.com)

The use of the technique of nuclear transfer for reproduction of human beings is surrounded by strong ethical concerns and controversies and is considered a threat to human dignity. (who.int)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)

Following the initial remarkable success of antibiotics, the emergence and spread of human pathogenic bacteria resistant to antibiotics has become a major phenomenon in the past fifty years. (europa.eu)
The emergence and spread of human pathogenic bacteria resistant to antibiotics has become a major problem in the past fifty years. (europa.eu)

Coadministration of efgartigimod with medications that bind to the human neonatal Fc receptor may lower systemic exposures and effectiveness of such medications. (medscape.com)
Clegg DJ, van Gemert M. Expert panel report of human studies on chlorpyrifos and/or other organophosphate exposures. (cdc.gov)
However, the acute traumatic injury models commonly used in pre-clinical testing are fundamentally different from the chronic and repeated exposures experienced by many human populations. (cdc.gov)

Human hepatocyte growth factor (HGF) is an 80kD pleiotropic protein that is endogenously produced by a variety of cell types from the mesenchymal cell lineage (such as cardiomyocytes and neurons). (wikipedia.org)
Here we show the differentiation of patient specific iPSCs derived from a patient with SFTPB deficiency into lung organoids with mesenchymal and epithelial cell populations from both the proximal and distal portions of the human lung. (nature.com)
The aim of adoptive T-cell therapy of cancer is to selectively confer immunity against tumor cells. (haematologica.org)
The data support the broad value of CD20 as safety switch in adoptive T-cell therapy. (haematologica.org)
T-cell clones were stimulated every 10-14 days with irradiated allogeneic PBMC and phyto-hemagglutinin in IMDM with 5% human serum (HS), 5% FBS and 100 IU/mL IL-2 as previously described. (haematologica.org)
The new technology is called 'beta cell encapsulation therapy' and serves to replace the insulin producing beta cells of the pancreas that are destroyed by type 1 diabetes. (diabetesdigest.com)
Our lab has worked for more than a decade on developing a cell therapy for Parkinson's disease (PD). (sloankettering.edu)
Insights from those studies should go toward further improving cell therapy for PD in the future. (sloankettering.edu)
We are interested in applying our ability to generate disease-relevant cell types and in establishing clinical-grade protocols for the development of cell therapy approaches in other CNS and PNS disorders. (sloankettering.edu)

Histological changes detected 7 days after the therapy were coagulated necrosis and fibrosis in the tissues ranging from 30-50% of the area. (spie.org)

The rat is widely accepted as more similar to the human in its physiology and therefore superior to the mouse, especially for metabolic, cardiac and neurological studies. (ca.gov)
Lu Rahman spoke to Ashley Zehnder, CEO of Fauna Bio, a biotech harnessing the power of comparative and functional animal genomics to find better therapies for human disease, including neurologic, metabolic, fibrotic and cardiovascular disorders. (ddw-online.com)

The purpose of this systematic literature review and meta-analysis is to identify the types of interventions in physical therapy contexts that have been explored in children with developmental coordination disorder, the most common variables being addressed, and whether these interventions are effective. (humankinetics.com)
This systematic search of MEDLINE, PEDro, CINAHL, SPORTDiscus, PsycINFO, and Cochrane Library identified interventions in physical therapy contexts for children and adolescents with DCD, and studies were screened using these criteria and assessed using the PEDro and NIH quality assessment scales. (humankinetics.com)
Data from 14 articles was extracted for inclusion in the meta-analysis, providing support for the effectiveness of physical therapy interventions against inaction. (humankinetics.com)
Researchers recommend the use of task-oriented and traditional physical therapy interventions for children with DCD. (humankinetics.com)
In addition, interventions in physical therapy contexts need clear goals and outcome measures for individual children. (humankinetics.com)
Although the differences among specific specialties within physical therapy have not been studied, one can expect a sports physical therapist to be well versed on the protocols and current research in sport. (humankinetics.com)
Others 21 have evaluated long-term outcomes in patients who completed a formal supervised physical therapy (PT) rehabilitation program compared with a home-based program, reporting equivalent improvements in self-reported quality of life. (humankinetics.com)
Since then, Healey and Huber have worked with WHA staff on nine projects related to physical activity promotion and access to physical therapy. (northwestern.edu)

Lentiviral (LV) vectors of the Retroviridae family show interesting properties for monogenic gene therapy, since they integrate into the host genome and allow long-lasting gene expression 22 . (nature.com)
On Friday, June 10th, BIO submitted comments in response to the FDA's draft guidance on developing human gene therapy products that incorporate genome editing (GE) of human somatic cells. (bio.org)

Professor Crowe, thank you for doing this interview with us today to update us on the work being done by you and your team, on SARS-CoV-2 human monoclonal antibodies for the COVID-19 pandemic. (hstalks.com)
Dr SHINOZAKI (Japan) commended WHO's efforts to tackle the threat of avian and human pandemic influenza. (who.int)

Developed from the post-modern Marxist approach and inspired by the Vygotksy development theory, it is a performatory therapy which is very little known in Brazil. (bvsalud.org)

Today's experts debate the benefits of and difference between genetic therapy and genetic enhancement, and the ethical impact of altering human evolution. (closertotruth.com)
Fauna's platform can highlight genetic networks that are different between the protected state of certain species - eg hibernators- and the disease state of humans. (ddw-online.com)
We can then layer onto those data genetic networks from human patients with failing hearts and pinpoint exactly which genes to target. (ddw-online.com)

The recorded voice of a real human infant emitted by robots enhances the robot's human-likeness and facilitates positive interaction between older adults and the robot. (frontiersin.org)
Doll therapy, which usually works by providing a human baby doll to older adults with dementia ( Mitchell, 2016 ), is one type of non-pharmacological intervention with a simulated social stimulus. (frontiersin.org)
Although typical doll therapy uses a baby doll without any interactive functions, robotic technology can enhance the interaction with older adults. (frontiersin.org)
Many believe that the therapy is only prescribed for children only , but it can actually benefit adults as well. (hiboox.com)
However, this does not mean that adults cannot be suitable for the therapy as well. (hiboox.com)

Use of rats to model human disease, however, has been limited until recently by the difficulty in modifying rat genes to mimic human conditions. (ca.gov)
For example," she adds, "we can examine what genes are changing in the hearts of hibernators at timepoints where they are protected from physiological conditions that resemble human heart attacks. (ddw-online.com)
Using a trans-species approach allows us to essentially 'geolocate' the key human disease genes more rapidly and with higher precision. (ddw-online.com)

The most well-known of these is Creutzfeldt-Jakob disease, which can be described as the naturally occurring human equivalent of mad cow disease. (infectioncontroltoday.com)
Can animal genomics help find therapies for human disease? (ddw-online.com)
Sepsis-like disease in infants due to human parechovirus type 3 during an outbreak in Australia. (cdc.gov)
discuss the potential and current applications for manipulating the human microbiome for disease prevention and management. (cdc.gov)

3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)

Lawyer speaks about the use of a controversial therapy for students with severe behavioural problems. (aljazeera.com)
Severe human parechovirus type 3 myocarditis and encephalitis in an adolescent with hypogammaglobulinemia. (cdc.gov)

Closely monitor for reduced effectiveness of medications that bind to the human neonatal Fc receptor. (medscape.com)

Annual sponsor of the Family Therapy Symposium offering continuing education for licensed mental health professionals. (ttu.edu)
Covenant Hospital Medical Family Therapy, Community Health Center, Early Head Start, Voice of Hope). (ttu.edu)
Capital Area Human Services introduces a new Adult Virtual Clinic offering teletherapy to individuals in need of behavioral health counseling. (cahsd.org)
If nanoparticle s accumulate in the human body or interact with the body molecules or chemical components, health risks may also occur. (cdc.gov)
Department of Health and Human Services. (cdc.gov)
Department of Health and Human Services five-point strategy does exactly that. (cdc.gov)

It invites the reader to go on a course of self-therapy designed to develop an awareness of the self and a growth of the personality. (whsmith.co.uk)
First published in 1951, Gestalt Therapy has remained constantly in print ever since and is regarded as one of the most important studies of self-awareness available. (whsmith.co.uk)
Kathleen combines Craniosacral Therapy and Linking Awareness with Massage Therapy, and sees great results with the combination of these modalities. (equinerehab.ca)

Paragraph 1 stated in that the causative agent, the H5N1 strain of Influenzavirus A , had crossed the species barrier and had infected humans, proving fatal in more than half the cases, whereas in paragraph 4 it was stated that no human case had been associated with any of the most recent animal outbreaks. (who.int)
The overarching goals of this final paper are to (1) review and summarize key information across contributions and (2) synthesize information to facilitate successful translation of otoprotective drugs from animal models into human application. (cdc.gov)

A phase I clinical trial entailed injecting an adenovirus vector with the human HGF (Ad-hHGF) gene into the coronary vessels localized to ischemic tissue. (wikipedia.org)

Anatomy21

Organisms43

Diseases20

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment43

Psychiatry and Psychology16

Phenomena and Processes77

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena5

Technology, Industry, Agriculture2

Humanities1

Information Science5

Health Care10

Geographicals1

Therapeutic9

Diseases15

Vitro5

Pluripotent stem2

20222

Papillomavirus1

Immunodeficiency virus2

Antiretroviral therapy6

Safety and efficacy of human2

Tisagenlecleucel1

Mice5

Mammals4

Lymphoma2

Suicide gene5

Antibiotic therapy2

Relapse1

Efficacy3

Clinical trials3

Treatment16

Stem3

Progression2

Adjunctive2

Photodynamic1

Preventive therapy2

Preclinical1

Begun1

Transplantation2

Etiology1

Sciences2

Study6

Infection4

Assess1

Toxicology1

Immune4

Dopamine2

Recombinant2

Gene transfer1

Nuclear2

Resistant2

Exposures3

Cell9

Fibrosis1

Metabolic2

Physical therapy8

Genome2

Pandemic2

Development1

Genetic3

Adults5

Genes3

Disease4

Implications1

Severe2

Effectiveness1

Health6

Awareness3

Animal2

Vector1