Loading...
  • graft-versus-
  • Ideally, such a therapy mediates direct antileukemic effects and strengthens the graft-versus-leukemia (GvL) reaction, while on the other hand is not associated with an extensive risk for severe graft-versus-host disease (GvHD) and offers an acceptable toxicity profile. (springer.com)
  • outcome
  • 001). This study shows a strong association between the degree to which BCR-ABL transcript numbers are reduced by therapy and long-term clinical outcome, supporting the use of time-dependent molecular measures to determine optimal response to therapy. (bloodjournal.org)
  • cellular
  • The program is certified by the Foundation for Accreditation of Cellular Therapy (FACT). (stjude.org)
  • To aid clinicians in their daily clinical practice, we also comment on some practical aspects such as dosing and schedule, the choice of HMA and the use of complementary cellular therapies. (springer.com)
  • chimerism
  • regulatory T cell populace observed in this individual suggests that these cells might contribute to the condition of mixed chimerism. (biopaqc.com)
  • As just recently reported, T regulatory cells (Treg) and natural monster 64232-83-3 (NK) populations may help to create chronic blended chimerism.6,7 HLA-mismatched transplants in human beings and rodents show that donor NK cells focus on web host hematopoietic tissues, getting rid of web host antigen-presenting cells, web host hematopoiesis, and web host leukemia. (biopaqc.com)
  • experimental
  • To test this hypothesis in preclinical settings, we have previously developed several experimental models of GVHD using TK+ T-cells in mice. (bioportfolio.com)
  • treatment
  • We have developed a strategy of alloreactive T-cell depletion, using T-cells expressing the Herpes simplex thymidine kinase (TK) suicide gene combined with a ganciclovir (GCV) treatment. (bioportfolio.com)
  • High dose corticosteroids with or without etanercept for the treatment of idiopathic pneumonia syndrome after allogeneic SCT. (upenn.edu)
  • myeloid neoplasms
  • Therapy-related myeloid neoplasms (t-MN) occur due to direct mutational events of chemotherapeutic agents and radiotherapy. (mjhid.org)
  • Therapy-related myeloid neoplasms are recognized as a separate entity in the World Health Organization (WHO) classification of haematological diseases. (mjhid.org)
  • clinical
  • Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue. (nih.gov)
  • Professor Dr Ralf Bartenschlager will be presented with the Lasker-DeBakey Clinical Medical Research Award, the unofficial 'American Nobel Prize in Medicine' / His work leading to the establishment of hepatitis C virus cell. (uni-heidelberg.de)
  • precursors
  • Developing proof signifies that apoptotic systems play a relevant function in the control of erythropoiesis under physiologic and pathologic circumstances.11 We hypothesized that Fas may contribute to the cell loss of life of SS erythroid precursors. (biopaqc.com)
  • mutations
  • These observations are consistent with the notion that residual cells bearing DTA mutations after induction therapy represent nonleukemic clones rather than persistent malignant disease," the researchers write. (medscape.com)