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  • sperm
  • The only exceptions are reproductive (egg and sperm) cells, known as 'haploid' cells because they contain a single set of 23 chromosomes. (phys.org)
  • These haploid cells cannot divide to make more eggs and sperm. (phys.org)
  • In the past decade, the number of techniques and procedures available to women and men trying to improve their fertility has exploded-especially in the area of in vitro fertilization, a procedure in which sperm and egg meet in a petri dish before they journey together to the uterus. (wired.com)
  • Many of the recent advances in IVF have been about selecting sperm, eggs, and embryos with the greatest chance of creating a successful pregnancy. (wired.com)
  • Cells from the sperm of a male are taken and injected into eggs extracted from the womb of a female. (marxist.com)
  • The donor sperm can be inserted directly into the woman's uterus. (ivf-mh.de)
  • The sperm can also be used to fertilize an egg cell outside of the body same as a regular IVF/ICSI treatment. (ivf-mh.de)
  • However, the treatment with donor sperm is not covered by health insurance so it has to be covered privately. (ivf-mh.de)
  • The use of donor sperm is strictly regulated in Germany. (ivf-mh.de)
  • Only donor sperm of non-anonymous donors may be used. (ivf-mh.de)
  • When choosing sperm it should be ensured that the donor physically fits the couple. (ivf-mh.de)
  • Treatment with donor sperm is, by legal provisions of the responsible medical chamber, only available to couples in a stable relationship (married or not) where one of the partners is not married to a third party. (ivf-mh.de)
  • The final effect of gametogenesis is the production of haploid sex gametes: the sperm and oocyte, which have only 23 chromosomes in each cell. (all.org)
  • conceive
  • Patient candidates include women with premature ovarian failure or severe genetic disorders, women who respond poorly to human menopausal gonadotropin, and women older than 40 years who do not conceive with use of other therapies. (opal-libraries.org)
  • Women with normal ovarian reserve (good eggs) may conceive via simple therapies (such as timed intrauterine insemination), while women with abnormal ovarian reserve (poor eggs) may require in-vitro fertilization (IVF) or even IVF with donor eggs. (inciid.org)
  • ovum
  • the terms egg and ovum (rather than oocyte) are rejected as unscientific. (all.org)
  • woman's
  • Prescribed IVF drugs boost a woman's hormones to super high levels to encourage eggs to mature. (wired.com)
  • The researcher extracted a sample from the woman's bone marrow and isolated about 5ml of cells. (siasat.com)
  • OVARIAN RESERVE describes a woman's capacity to produce a reasonable quantity of good quality eggs. (inciid.org)
  • Of course, measuring a woman's ovarian reserve is very important in determining why someone may not be getting pregnant, as well as in finding out the ease (if she has good eggs) or difficulty (if she has poor eggs) with which a pregnancy may be realized. (inciid.org)
  • procedure
  • The current experiment used seven young women as egg donors (a procedure known to risk their health), collecting a total of 126 eggs for experiments, but resulting in only two cell lines. (cmda.org)
  • In general, the IVF procedure results in a surplus of leftover eggs. (ivf.net)
  • It is hoped that the technique can be developed into a female infertility treatment to replace HRT with a one-time surgical procedure for women who experience severe menopause symptoms," said Dr Prabhu Mishra, CEO and co-founder StemGenn Therapeutics, a company that specialises in retrieval of best quality stem cells. (siasat.com)
  • According to Dieter Egli of the New York Stem Cell Foundation Research Institute, who led the new study, the procedure shouldn't be used until a solution is found. (indiatimes.com)
  • MSCs
  • MSCs are purified from the marrow, cultured and packaged, with up to 10,000 doses derived from a single donor. (wikipedia.org)
  • genomic
  • In other words, the egg needs to erase all tissue-specific memories from the skin cell and revert it into a genomic blank slate. (eurekalert.org)
  • nuclear
  • Unlike nuclear DNA, which is inherited from both parents, mitochondrial DNA is passed down only from the mother via her egg. (newscientist.com)
  • However, the SPECIES (biological class or category) to which an individual belongs is determined only by the number of nuclear chromosomes per cell. (all.org)
  • There are ethical concerns surrounding nuclear transfer, particularly regarding recruitment and compensation for egg donors needed for stem cell research. (empr.com)
  • Oocytes
  • the terms fertilized oocytes and fertilized egg are rejected as unscientific. (all.org)
  • sheep
  • According to Sir Ian Wilmut, the creator of the first cloned animal (Dolly the sheep), "Immune reaction is one of the most serious problems facing the development of stem cell therapy, and cell lines of this type may enable us to treat a large number of patients without immune rejection, offering an enormous practical advantage. (lifeboat.com)
  • The term "stem cell research" was until recent years to be found only in obscure scientific and medical journals, but since the phenomenon of Dolly the sheep less than a decade ago most people have heard the phrase. (marxist.com)
  • By carefully controlling the fertilised cell and using the female sheep as a carrier of the fertilised cell, Wilmut created Dolly - an exact copy of the Dorset Finn sheep. (marxist.com)
  • The cloned sheep will be genetically identical to this donor. (prezi.com)
  • laboratory
  • In healthy adult laboratory animals, progenitor cells migrate within the brain and function primarily to maintain neuron populations for olfaction (the sense of smell). (wikipedia.org)
  • The Nature report says that PhD student Ja Min Koo originally said that the donors had included herself and another woman who worked in Hwang's laboratory. (ivf.net)
  • differentiate
  • Understanding the fundamentals of biological decisions, including what permits a cell to maintain pluripotency, that is, its ability to self-renew and thereby remain immortal, or to differentiate into multiple types of cells, is of profound importance. (biomedcentral.com)
  • HESCs are characterized by their capacity for self-renewal and their ability to differentiate into all types of cells of the body. (stanford.edu)
  • research
  • The research, described in Thursday's online edition of the journal Cell Stem Cell , is a controversial advance likely to reopen the debate over the ethics of human cloning. (cmda.org)
  • Paul Knoepfler, an associate professor at the University of California at Davis who studies stem cells, called the new research "exciting, important and technically convincing. (cmda.org)
  • This study has given us a new type of human stem cell that will have an important impact on human genetic and medical research," said Nissim Benvenisty, MD, PhD, Director of the Azrieli Center for Stem Cells and Genetic Research at the Hebrew University of Jerusalem and principal co-author of the study. (phys.org)
  • Being able to affect single-copy genes in haploid human stem cells has the potential to facilitate genetic analysis in biomedical fields such as cancer research, precision and regenerative medicine. (phys.org)
  • One of the greatest advantages of using haploid human cells is that it is much easier to edit their genes," explained Ido Sagi, the PhD student who led the research at the Azrieli Center for Stem Cells and Genetic Research at the Hebrew University of Jerusalem. (phys.org)
  • This work is an outstanding example of how collaborations between different institutions, on different continents, can solve fundamental problems in biomedicine," said Dieter Egli, PhD, principal co-author of the study, and Assistant Professor of Developmental Cell Biology in Pediatrics at Columbia University Medical Center and a Senior Research Fellow at the NYSCF Research Institute and a NYSCF-Robertson Investigator. (phys.org)
  • The research, supported by The New York Stem Cell Foundation, the New York State Stem Cell Science Program, and by the Azrieli Foundation, underscores the importance of private philanthropy in advancing cutting-edge science. (phys.org)
  • Women who donate some of their eggs to stem cell research will receive half-price discounted IVF treatment - a 1,500 stipend reducing the costs of one cycle of IVF treatment from 3,000 - at the Newcastle Fertility Centre. (ivf.net)
  • I agree that the left over eggs from IVF would be of more use if they were kept rather than destroyed, if they can be of help to research then what harm is there. (ivf.net)
  • NIH Draft Guidelines on Stem Cell Research: A Work in Progress? (thehastingscenter.org)
  • But when the NIH published its draft guidelines on stem-cell research last month, it emerged that the constraints weren't quite as loose as many Obama supporters had hoped they might be. (thehastingscenter.org)
  • The draft guidelines permit federal funding of research on "excess" human embryos from fertility clinics, and of stem cell lines developed from such embryos. (thehastingscenter.org)
  • Problems include failure to inform donors about the nature of stem cell research. (thehastingscenter.org)
  • Both research papers are published online in the journal Cloning and Stem Cells. (lifeboat.com)
  • From 1998 to 2002, he was Director of Marketing of Human Cell Systems at BioWhittaker Corporation, a Cambrex Company (Walkersville, Maryland) where he expanded the company's research products portfolio into new fields, including stem cells, and created and implemented the strategy of moving human cell-based research products into the clinical markets. (lifeboat.com)
  • More research is needed to understand the potential of these stem cells. (wittysparks.com)
  • Research has been conducted on the effects of stem cells on animal models of brain degeneration , such as in Parkinson's , Amyotrophic lateral sclerosis , and Alzheimer's disease . (wikipedia.org)
  • For years, those afflicted with chronic disease have seemingly been pitted against those who consider stem cell research immoral due to the destruction of embryos. (thehastingscenter.org)
  • Advocates of stem cell research are downplaying iPS cells as "hype" after years of routinely exaggerating the potential of embryonic stem cells. (thehastingscenter.org)
  • Responding to commentators who voice hopes that the stem cell wars could be drawing to a close, these enthusiasts have focused on the shortcomings and early stage of research with iPS cells while ignoring the many remaining uncertainties of embryonic stem cells. (thehastingscenter.org)
  • Much of what we know about pluripotency - which is what makes stem cells potentially useful for therapies - is known from research on embryonic stem cells. (thehastingscenter.org)
  • The lack of progress in cloning-based stem cell research and its problematic social consequences, as well as the appearance of a more promising alternative, led prominent cloning researcher Ian Wilmut to put it on the back burner. (thehastingscenter.org)
  • With more research and clinical studies, it is hoped that such post-menopausal women will get relief from their symptoms and benefit from this therapy. (siasat.com)
  • In recent attempts to alleviate the symptoms of t hese d iseases, research has turned to the capabilities of gene therapy as a tool for treatment . (issuu.com)
  • Nature's claim is totally groundless', he told the Korea Times, adding: 'I swear none of my students donated eggs for the research. (ivf.net)
  • LOS ANGELES -- The California stem cell agency today approved $68 million in grants for early translational research and left open the possibility that more might be awarded in June. (blogspot.com)
  • With these early translational grants CIRM has taken the first step in funding translational research that will be critical for the development of future therapies. (blogspot.com)
  • The board additionally approved $200,000 to co-sponsor the annual convention of the International Society for Stem Cell Research in San Francisco during the summer of 2010. (blogspot.com)
  • In this review we provide an overview of the most important ethical issues in stem cell research and therapy, as a contribution to the debate about their clinical use in regenerative and transplantation medicine. (medsci.org)
  • Human embryonic stem cell (HESC) research offers much hope for alleviating the human suffering brought on by the ravages of disease and injury. (stanford.edu)
  • The standard view of those who oppose HESC research is that a human being begins to exist with the emergence of the one-cell zygote at fertilization. (stanford.edu)
  • Years of research on monkey cells using the same technique have not successfully produced any monkey clones. (medindia.net)
  • By action, the governor means a ballot measure approved by California voters that provides $300 million a year for stem-cell research for the next decade. (npr.org)
  • There are only going to be a few cutting-edge stem-cell research centers built around the world, whether Cambridge, England or Cambridge, Massachusetts or Connecticut, and they're all getting rooted right now," he said. (npr.org)
  • So we have gotten in the game, and we will be one of those stem-cell research centers. (npr.org)
  • Patients with diabetes may one day benefit from stem cell therapy, as research published in the journal Nature describes the first insulin-producing cells containing the DNA of a 32-year-old woman with type 1 diabetes. (empr.com)
  • germ
  • Because their genetic content is equivalent to germ cells, they might also be useful for reproductive purposes. (phys.org)
  • They emphasise that gene therapy and tissue donation are not considered to be genetic modification either - although this is possibly because these procedures do not involve heritable (germ-line) genetic changes. (phgfoundation.org)
  • there are two basic categories of diploid cells: somatic, or body, cells and germ line cells, or future sex gametes. (all.org)
  • In this review, we consider the mRNAs and novel genes with unique expression and imprinting patterns that were discovered using systems biology approaches with primate pluripotent stem and germ cells. (biomedcentral.com)
  • Overwhelmingly, your Lordships will deplore anything that smacks of eugenics or of germ-line gene therapy. (davidalton.net)
  • development
  • Some lawmakers called for a ban on reproductive human cloning, but others refused to support such legislation unless it included a ban on human cloning whether it was for the purposes of reproduction or for the development of new therapies. (cmda.org)
  • Jeffrey led the product development and marketing of the Clonetics brand, consisting of over 200 human cell and reagent products. (lifeboat.com)
  • Another experimental technique called in vitro activation has doctors surgically remove parts of the ovary and treat them with enzymes to artificially jump-start egg development in women who've stopped ovulating. (wired.com)
  • A few months ago, the development of a new method to derive stem cells provided the opportunity to shake up these divisive politics. (thehastingscenter.org)
  • I am eager to see the development of cell therapies derived from pluripotent stem cells. (futurepundit.com)
  • These new human beings immediately produce very specific human proteins and enzymes and continuously form very specific human cells, tissues and organs throughout development. (all.org)
  • This new single-cell human being immediately directs his/her own further continuous human growth and development by producing specifically human proteins and enzymes. (all.org)
  • These grants are intended to either lead to a drug candidate for an unmet medical need or address a bottleneck in the development of new therapies. (blogspot.com)
  • This process of disaggregating the blastocyst's cells eliminates its potential for further development. (stanford.edu)
  • tissue
  • A number of studies have showed a possible connection between stem cell treatments and the growth of new skin tissue and increased collagen production. (wittysparks.com)
  • Cloning
  • Growing 'stem cells from adults using cloning techniques' sounds innocent, as if they had taken one heart cell and multiplied it in a dish. (cmda.org)
  • Cloning relies on eggs to make the new, living clones, no matter their intended final use. (cmda.org)
  • diploid
  • A haploid cell with 23 chromosomes (left), and a diploid cell with 46 chromosomes (right). (phys.org)
  • Human cells are considered 'diploid' because they inherit two sets of chromosomes, 46 in total, 23 from the mother and 23 from the father. (phys.org)
  • Previous efforts to generate embryonic stem cells using human egg cells had resulted in diploid stem cells. (phys.org)
  • They then highlighted the DNA with a fluorescent dye and isolated the haploid stem cells, which were scattered among the more populous diploid cells. (phys.org)
  • In diploid cells, detecting the biological effects of a single-copy mutation is difficult, because the other copy is normal and serves as "backup. (phys.org)
  • While somatic cells are diploid, gametes are only haploid. (biomedcentral.com)
  • doses
  • By using a mild stimulation with low doses of hormone supplement, the egg maturation can be improved and by triggering ovulation the optimal moment for sexual intercourse can be determined. (ivf-mh.de)