Therapeutic vaccine therapeutic papillomavirus vaccines. Medical search. Frequent questions

Eighty-seven percent agreed that HPV vaccines could prevent cervical cancer, 73% that the vaccine has to be administered before the onset of sexual activity, 89% would recommend vaccination to their daughters and nieces. (nih.gov)
The Company is also developing therapeutic vaccines for cervical cancer. (stockhouse.com)
They are applying this platform to develop HIV vaccines and creating new therapeutic vaccines against human papillomavirus (HPV), a leading cause of cervical cancer, and chronic hepatitis B virus infection, a major cause of hepatocellular carcinoma. (wistar.org)
Human papillomavirus (HPV) infection is now recognized as the main cause of cervical cancer, the role of coexisting factors is better understood, a new cytology reporting terminology has improved diagnosis and management of precursor lesions, and specific treatment protocols have increased survival among patients with early or advanced disease. (cmaj.ca)
This trend, suggestive of a resurgence in cervical cancer, has also been observed in many European countries and could reflect increased cancer detection by the use of new diagnostic techniques, such as human papillomavirus (HPV) testing and cervicography, or it could be the result of a cohort effect. (cmaj.ca)
SCT-1000 is under development for the prevention of human Papillomavirus (HPV) associated cancers such as genital wart, cervical cancer, anal cancer, head and neck cancer, vaginal cancer, adenocarcinoma and vulvar cancer. (pharmaceutical-technology.com)
human papillomavirus therapeutic vaccine that targets HPV 16 and HPV 18 for cervical cancers and precancerous cervical dysplasia. (defenseworld.net)
The most effective way to prevent cervical cancer is to give HPV vaccines to both boys and girls, reports a collaborative study. (sciencedaily.com)
The prophylactic vaccines are against the hepatitis B virus, which can cause liver cancer, and against human papillomavirus types 16 and 18, which are responsible for about 70 percent of cervical cancer cases. (biomedcentral.com)
Inovio Pharmaceuticals , a developer of therapeutic and preventive vaccines against cancers and infectious diseases, has reported long-term durability of T cell immune responses of up to over two years (at the latest time measured) in seven of eight evaluated patients following a fourth vaccination of VGX-3100, its investigational SynConR DNA vaccine for treating cervical dysplasia and cancer caused by human papillomavirus (HPV) that is delivered using intramuscular electroporation. (centerwatch.com)
Inovio's original phase I, designated HPV-001, treated 18 women who had previously been diagnosed with and surgically treated for high grade cervical intraepithelial neoplasia (CIN 2/3), a premalignant lesion that may lead to cervical cancer, with a three-vaccination regimen of its VGX-3100 therapeutic DNA vaccine delivered with its CELLECTRAR electroporation device. (centerwatch.com)
I watched a video online discussing the harmful effects of the cervical cancer vaccine, Gardasil. (cancer.org.au)
The HPV vaccine is not a replacement for regular Cervical Screening Tests . (cancer.org.au)
Human papillomaviruses (HPVs) are associated with a variety of epithelial lesions, including benign genital warts and cervical intraepithelial neoplasia [ 1 ]. (biomedcentral.com)
Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer. (jia-lab.com)
Human papillomavirus genotyping using next generation sequencing (NGS) in cervical lesions: Genotypes by histologic grade and their relative proportion in multiple infections. (who.int)
The major risk factor associated with cervical cancer is human papillomavirus (HPV) infection which generally occurs in adolescence after the first acts of sexual intercourse. (who.int)

The current HPV vaccine recommendations apply to 9 years old and above through the age of 26 years and adults aged 27-45 years who might be at risk of new HPV infection and benefit from vaccination. (mdpi.com)
Therapeutic human papillomavirus (HPV) vaccine candidates constructed with iBioModulator provided superior protection from HPV-16 E7-induced tumors and extended survival in a mouse model when compared with vaccination with native E7 protein alone. (globenewswire.com)
Effective therapeutic vaccination to treat HPV-induced cancer has been a long-desired but difficult to achieve objective of healthcare professionals. (globenewswire.com)
Response magnitudes remain high and three subjects are responding to additional antigens (among the four antigens encoded by the vaccine) that they were not previously responding to prior to this fourth vaccination. (centerwatch.com)
Adverse side effects of therapeutic vaccination and lack of awareness may threaten the global therapeutic vaccines market's expansion. (marketdataforecast.com)
Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication. (hervolutiontx.com)
AAVP meets Spanish Health Ministry representatives to ask for the withdrawal of HPV vaccines from the Official vaccination schedule of Spain and informs there are three cases of suspected death and numerous cases of suspected serious adverse reactions in our country and around the world. (sanevax.org)
Alicia Capilla stated that Spanish Health Authorities have not been responsible because families did not receive information prior to vaccination about the risks their daughters have suffered after receiving the HPV vaccine, thus the right we have as citizens to have therapeutic informed consent has been violated. (sanevax.org)
However, low dose inoculations via the IP or SC route or IN vaccination elicited vaccine-induced CD8 + T cell responses that did not reach protective thresholds for tumor protection. (bmj.com)
Two earlier trials of therapeutic vaccination demonstrated either a clinical complete response or a clinical partial response in women with vulvar or vaginal dysplasia. (medscape.com)
Evaluation of immune response to single dose of quadrivalent HPV vaccine at 10-year post-vaccination. (who.int)
Contraindications (conditions in a recipient that increases the risk for a serious adverse reaction) to vaccination are conditions under which vaccines should not be administered. (cdc.gov)
However, a vaccination might be indicated in the presence of a precaution if the benefit of protection from the vaccine outweighs the risk for an adverse reaction. (cdc.gov)
This precaution avoids causing diagnostic confusion between manifestations of the underlying illness and possible adverse effects of vaccination or superimposing adverse effects of the vaccine on the underlying illness. (cdc.gov)

Novel laboratory mouse papillomavirus (MusPV) infection. (nature.com)
Despite low awareness of HPV infection, the majority of respondents would recommend or are ready to receive the HPV vaccine, but the cost could prevent its acceptability. (nih.gov)
Prophylactic vaccines for genital human papillomavirus (HPV) infection have been shown to be feasible in animal models, and suitable vaccine material based on virus-like particles can be produced in bulk at reasonable cost. (nih.gov)
Therapeutic vaccines for genital HPV infection are also possible, but have not yet been demonstrated as feasible in practice because the choice of vaccine antigens is difficult, the method of their optimal delivery is uncertain, and the nature of the relevant antiviral immunity is unknown. (nih.gov)
citation needed] Recently, the company began collaborating with Emory University on the development of a therapeutic vaccine for human papillomavirus (HPV) infection, with a specific focus on head and neck cancer (HNC). (wikipedia.org)
The long-term therapeutic goal is to develop a vaccine-based mechanism to treat infected individuals that either prevents or significantly slows progression to symptomatic HIV, including AIDS, by stimulating an infected individual's immune system to resist the progression of infection. (wikipedia.org)
Current research has focused on the determinants of infection with oncogenic HPV types, the assessment of prophylactic and therapeutic vaccines and the development of screening strategies incorporating HPV testing and other methods as adjunct to cytology. (cmaj.ca)
Collectively, the data from these completed trials have shown immune responses from Vaxart's oral norovirus vaccine constructs to be strong, long-lasting, and comparable to natural infection. (itbusinessnet.com)
Coadministration with a HDAC inhibitor inhibits innate immunity transiently to promote infection and spread of OVs, and significantly enhances anti-tumor immunity and improves the therapeutic index. (biomedcentral.com)
Since early 2018, young Australians have been given free access to the new HPV vaccine, Gardasil ® 9 which protects against more types of HPV infection. (cancer.org.au)
Treatment is not recommended for subclinical anogenital or mucosal human papillomavirus (HPV) infection in the absence of coexistent dysplasia. (medscape.com)
Although vaccines to protect against these types of HPV have been around for some time ( Gardasil/Cervarix), they are meant to provide protection against infection. (drwaynecottrell.com)
This study was performed with aim to evaluate the vaccines available or under investigation to prevent or treat HPV infection. (ac.ir)
Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES. (bvsalud.org)

Currently, two prophylactic vaccines against oncogenic HPV16 and HPV18, the genotypes predominantly found in cancers, and a new vaccine directed against 9 HPV serotypes have demonstrated their efficacy in non-HPV-infected individuals. (aacrjournals.org)
In addition, human papillomavirus-mediated cancers will present a growth opportunity for the global therapeutic vaccines market. (marketdataforecast.com)
Efficacy and Synergy with Cisplatin of an Adenovirus Vectored Therapeutic E1E2E6E7 Vaccine against HPV Genome-Positive C3 Cancers in Mice. (hervolutiontx.com)
Adenovirus based virus-like-vaccines targeting endogenous retroviruses can eliminate growing colorectal cancers in mice. (hervolutiontx.com)
Control mice that were given implants without the vaccine material died from their cancers within 25 days. (nih.gov)

However, these vaccines failed to demonstrate any clinical activity in subjects already infected with HPV with 14 million new HPV infections each year in the world. (aacrjournals.org)
The medications used to treat human papillomavirus (HPV) infections are primarily designed to ablate the lesion by virtue of their corrosive properties. (medscape.com)
Ertl's research centers on developing vaccines for an array of diseases and conditions-including AIDS , chronic viral infections, COVID -19 and some forms of cancer-not typically considered to be treated using this approach. (wistar.org)
These vaccines aim to protect against future infections and look to create new therapies for diseases already affecting people. (wistar.org)
they are only useful for cancer known to be caused by infections, such as the HPV (human papillomavirus) vaccine. (canceraustralia.gov.au)
These anti-viral vaccines are highly effective in curbing virus infections and onset of cancer. (biomedcentral.com)
Therapeutic Vaccine Against Primate Papillomavirus Infections of the Cervix. (hervolutiontx.com)
Natural History of Incident and Persistent Cutaneous Human Papillomavirus and Human Polyomavirus Infections. (who.int)
Methods: In this review study, the keywords of HPV, cervix cancer, DNA vaccine, RNA vaccine, and prevention or treatment of HPV infections were searched in databases of PubMed, Science direct, Scopus and Google Scholar from 2000 to 2018. (ac.ir)
Members of the human herpesvirus (HHV) and human papillomavirus (HPV) families cause the most common primary viral infections of the oral cavity. (medscape.com)

Here we show that T cell immunity against commensal papillomaviruses suppresses skin cancer in immunocompetent hosts, and the loss of this immunity-rather than the oncogenic effect of HPVs-causes the markedly increased risk of skin cancer in immunosuppressed patients. (nature.com)
The laboratory developed an adenovirus-based vaccine against rabies virus that can provide rapid immunity following a single administration. (wistar.org)
Beside personal immunity, such use of the vaccine also induces a herd immunity that will help to eradicate the carcinogenic virus types more quickly. (sciencedaily.com)
In addition, whereas weak pre-existing immunity did not alter the protective thresholds of the vaccine-specific T cell response following subsequent immunization with CMV-based vaccine vectors, strong pre-existing immunity inhibited the development of vaccine-induced T cells and their control on tumor progression. (bmj.com)
Usually, when we think of vaccines, we think of preventive vaccines, and most commonly the goal is to provide immunity to an infectious agent. (nih.gov)
The researchers hope that, like vaccines that confer long lasting immunity to infectious diseases, this new vaccine may endow patients with resistance that keeps the cancer from coming back. (nih.gov)
Conclusion:Nucleic acid vaccines have promising outcomes due to safety, stability, simplicity of providing and ability to induce antigen-specific immunity. (ac.ir)
A precaution is a condition in a recipient that might increase the risk for a serious adverse reaction, might cause diagnostic confusion, or might compromise the ability of the vaccine to produce immunity (e.g., administering measles vaccine to a person with passive immunity to measles from a blood transfusion administered up to 7 months prior) ( 7 ). (cdc.gov)

In this issue of Clinical Cancer Research , van Poelgeest and colleagues report the clinical results of a therapeutic human papillomavirus (HPV) vaccine for the treatment of premalignant anogenital lesions ( 1 ). (aacrjournals.org)
To investigate the effects of papillomavirus on carcinogen-driven skin cancer, we colonized several strains of immunocompetent mice with mouse papillomavirus type 1 (MmuPV1) 5 . (nature.com)
Howley, P. M. & Pfister, H. J. Beta genus papillomaviruses and skin cancer. (nature.com)
Vaccines that aim to expand tumor-specific CD8 (+) T cells have yielded disappointing results in cancer patients although they showed efficacy in transplantable tumor mouse models. (wistar.org)
Using a system that more faithfully mimics a progressing cancer and its immunoinhibitory microenvironment, we show that in transgenic mice, which gradually develop adenocarcinomas due to expression of HPV -16 E7 within their thyroid, a highly immunogenic vaccine expressing E7 only induces low E7 -specific CD8 (+) T-cell responses, which fail to affect the size of the tumors. (wistar.org)
The main types of immunotherapy can be divided into treatments using monoclonal antibodies, nonspecific immunotherapies, and cancer vaccines. (canceraustralia.gov.au)
Cancer vaccines are medicines that trigger the body's immune system to detect cancer cells. (canceraustralia.gov.au)
There are 2 types of cancer vaccines. (canceraustralia.gov.au)
Treatment (therapeutic) vaccines prompt the immune system to fight existing cancer cells. (canceraustralia.gov.au)
For example, sipuleucel-T is a cancer vaccine used to treat prostate cancer. (canceraustralia.gov.au)
SinoCelltech Group (SinoCelltech), formerly Beijing Shenzhou Cell Biotechnology Group, is a biopharmaceutical company that discovers, develops monoclonal antibodies, vaccines and recombinant proteins for treatment of cancer, psoriasis and rheumatoid arthritis. (pharmaceutical-technology.com)
With this favorable immune backdrop, genetic engineering of OVs and rational combinations further potentiate OVs as cancer vaccines. (biomedcentral.com)
In summary, OVs properly armed or in rational combinations are potent therapeutic cancer vaccines. (biomedcentral.com)
Cancer vaccines are designed to boost the body's immune system to protect itself from carcinogenesis and progression of cancer. (biomedcentral.com)
The Food and Drug Administration of the USA has approved both prophylactic and therapeutic vaccines for cancer in the last few years. (biomedcentral.com)
In contrast, therapeutic cancer vaccines are difficult to develop and much less effective. (biomedcentral.com)
As a benchmark, Provenge, a cancer vaccine designed to treat advanced prostate cancer, demonstrated an increase in survival and thus gained approval from the FDA for use in the treatment of advanced prostate cancer patients in 2010[ 10 ]. (biomedcentral.com)
The approval of Provenge has stimulated interest in development of other therapeutic cancer vaccines. (biomedcentral.com)
OVs provide a number of potential advantages as cancer vaccines over conventional therapies. (biomedcentral.com)
First, OVs are tumor-selective, thus in situ cancer vaccines, providing higher cancer specificity and better safety margin. (biomedcentral.com)
However, just like other immunotherapeutic regimens, a number of challenges remain for OVs-mediated cancer vaccines. (biomedcentral.com)
The growing number of people suffering from diseases such as cancer, HIV, neurological diseases, autoimmune diseases, infectious diseases, and others is significantly increasing the need for therapeutic vaccines and promoting market growth. (marketdataforecast.com)
Due to the increasing incidence of diseases like cancer and HIV, therapeutic vaccines have become more popular. (marketdataforecast.com)
Technological advancements in HIV diagnosis and increased clinical trials for HIV and cancer vaccines are anticipated to favor the therapeutic vaccines market. (marketdataforecast.com)
Several pharmaceutical companies have begun developing novel vaccines for breast cancer, lung cancer, and Alzheimer's. (marketdataforecast.com)
Immunogenicity of Human Endogenous Retroviral Proteins in Cancer and Discussion of Therapeutic Approaches. (hervolutiontx.com)
Background The capacity of cytomegalovirus (CMV) to elicit long-lasting strong T cell responses, and the ability to engineer the genome of this DNA virus positions CMV-based vaccine vectors highly suitable as a cancer vaccine platform. (bmj.com)
Methods We generated CMV-based vaccine vectors expressing the E7 epitope and tested these in preclinical models of HPV16-induced cancer. (bmj.com)
Together, these results may hold importance for cancer vaccine development to achieve high efficacy in vaccine recipients. (bmj.com)
This aspirin-sized disk is the first therapeutic cancer vaccine implanted beneath the skin [1]. (nih.gov)
Therapeutic cancer vaccines are a new, and hot, research area. (nih.gov)
A couple of cancer vaccines have already been approved by the FDA. (nih.gov)
And so, some researchers began to look for a simpler, and perhaps more effective, way to make therapeutic cancer vaccines. (nih.gov)
No other cancer vaccine to date has shown such an effective anti-tumor response. (nih.gov)
Is there a vaccine for prostate cancer post-radical surgery and radiation therapy? (nih.gov)
Human papillomavirus and human immunodeficiency virus (HIV) coinfection accelerates progression towards cancer. (who.int)

iBioModulator has been used as a fusion to express peptide or protein domain antigens in a number of other successful vaccine candidates, including those for anthrax, plague, sleeping sickness and influenza. (globenewswire.com)
The iBioModulator also has been used by scientists at the Fraunhofer USA Center for Molecular Biotechnology to improve the solubility and stability not only of recombinant vaccine antigens, but other proteins as well. (globenewswire.com)
This is one of the first studies that have had such a high success rate and in addition evidence that the vaccine elicits specific T cell response by targeting HPV antigens in dendritic cells. (drwaynecottrell.com)

Combination with other immunotherapy regimens improve overall therapeutic efficacy. (biomedcentral.com)
Taking into account all this data, we have requested the Health Ministry to investigate seriously the efficacy of this vaccine. (sanevax.org)

We are pursuing applications of this technology for both therapeutic and preventive vaccines. (globenewswire.com)

The HPV 9-valent (Gardasil 9) is the only HPV vaccine available in the United States. (medscape.com)
The HPV 2-valent vaccine (Cervarix), which covered types 16 and 18, and the HPV 4-valent vaccine (Gardasil), which covered types 6, 11, 16, and 18, were discontinued in the United States in October 2016. (medscape.com)
Does the Gardasil vaccine do more harm than good? (cancer.org.au)
Current evidence indicates the two vaccines developed to protect against human papillomavirus (HPV) , Gardasil and Cervarix, are effective and safe to use. (cancer.org.au)
Gardasil ®9 has been approved for use in Australia by the Therapeutic Goods Administration, and overseas by the US Food and Drug Administration and the European Medicines Agency. (cancer.org.au)

Based on disease, the autoimmune disease segment held the leading therapeutic vaccines market share in 2022. (marketdataforecast.com)
North America led the therapeutic vaccines market worldwide in 2022. (marketdataforecast.com)

Garland et al, in a study analyzing pregnancy and infant outcomes in women who received prophylactic quadrivalent HPV vaccine before becoming pregnant, observed no significant differences among live birth, fetal loss, or spontaneous abortion. (medscape.com)

van Poelgeest and colleagues report the ability of ISA 101 vaccine [13 HPV16 E6 and E7 synthetic long peptides mixed with the Montanide adjuvant] without additional treatment to induce objective partial or complete histologic regression of the lesions in more than 50% of patients with high-grade vulvar (VuVIN3) and vaginal intraepithelial neoplasia (VaIN3) with a follow-up of 12 months ( 1 ). (aacrjournals.org)

Our bivalent vaccine is designed to target the most important genogroups, GI and GII, and specifically to cover the important strains, GI.1 and GII.4. (itbusinessnet.com)

The data further highlights the viability of using multiple booster vaccinations with a DNA vaccine delivered using electroporation, in contrast to other non-replicating vaccine vectors that may induce unwanted immune responses against the vector after multiple vaccinations. (centerwatch.com)
The potential of adenoviral vaccine vectors with altered antigen presentation capabilities. (hervolutiontx.com)
Conclusions This study highlight the effectiveness of CMV-based vaccine vectors, and shows that demarcated thresholds of vaccine-specific T cells could be defined that correlate to tumor protection. (bmj.com)

Norovirus is the leading cause of acute viral gastroenteritis in all age groups in the U.S. There are no approved vaccines for noroviruses. (itbusinessnet.com)
MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans. (hervolutiontx.com)
The vaccine resulted in complete viral clearance in conjunction with lesion regression in 7 out of the 9 participants in the study. (drwaynecottrell.com)

Its programs include tablet vaccine candidates designed to protect against norovirus, coronavirus, seasonal influenza, and respiratory syncytial virus (RSV), as well as a. (stockhouse.com)
Ongoing studies will include evaluation of the benefits of using the iBioModulator in the development and production of therapeutic product candidates. (globenewswire.com)
Our norovirus vaccine candidates are the only ones formulated for oral administration and optimized for delivery to the gastrointestinal system, the site at which norovirus enters the body. (itbusinessnet.com)
Design and Immunological Validation of Macaca fascicularis Papillomavirus Type 3 Based Vaccine Candidates in Outbred Mice: Basis for Future Testing of a Therapeutic Papillomavirus Vaccine in NHPs. (hervolutiontx.com)

Health-care facilities are held to standards of offering influenza vaccine for hospitalized patients, so providers are incentivized to vaccinate these patients at some point during hospitalization ( 15 ). (cdc.gov)

Collectively, these results identify a novel role for SOX9 as a potential therapeutic marker for the prevention and treatment of NPC. (cancerindex.org)

citation needed] In human clinical trials of the company's HIV vaccines, GeoVax demonstrated that VLPs are safe and eliciting both strong and durable humoral and cellular immune response. (wikipedia.org)

The iBioModulator platform is complementary to the iBioLaunch platform and designed to significantly improve vaccine products with both higher potency and greater duration of effect. (globenewswire.com)
Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency. (yale.edu)
This adjuvant allows our vaccine platform to be administered without any additional adjuvant, and because all of the vaccine components are in the one molecule, it ensures that all vaccine components are delivered to the same cell, significantly improving vaccine potency. (moylelab.com)

The vaccines are being tested for T and B cell responses in mice. (wistar.org)
An Endogenous Retrovirus Vaccine Encoding an Envelope with a Mutated Immunosuppressive Domain in Combination with Anti-PD1 Treatment Eradicates Established Tumours in Mice. (hervolutiontx.com)
The capacity for these vaccines to reduce/clear a HPV-16 tutor model (TC-1 cells) was assessed in C57BL/6 mice. (moylelab.com)
The team tested their vaccine implant in mice with melanoma. (nih.gov)
Mice that received one vaccine implant showed slower tumor growth, some tumor regression, and survived longer. (nih.gov)
Of the mice that received two vaccine implants, half completely eliminated all tumors. (nih.gov)

The lab is applying its adenovirus vaccine expertise against SARS-CoV-2, utilizing a modified chimpanzee virus as a vaccine delivery vehicle to induce an immune response. (wistar.org)

Different human papillomavirus types share early natural history transitions in immunocompetent women. (who.int)

citation needed] The GeoVax program has been added to the "Draft Landscape of COVID-19 Candidate Vaccines" by the World Health Organization. (wikipedia.org)

During 2010, the AIDS Research Consortium of Atlanta (ARCA) began patient recruitment for a Phase 1 clinical trial sponsored by GeoVax Labs, Inc., investigating GeoVax's DNA/MVA vaccine as a treatment for individuals already infected with HIV. (wikipedia.org)
The alarming rise in the demand for effective treatment has shifted global attention to therapeutic vaccines. (marketdataforecast.com)
After analyzing the GVAX treatment data, we found that the GVAX vaccine could facilitate tumor growth. (ncl.edu.tw)
History of hypersensitivity to the treatment vaccines. (who.int)

25 years, 91% would agree to receive the vaccine if it is publicly funded, but only 72% would agree to pay $100/dose. (nih.gov)
This vaccine also achieves long-term protection in non-human primates after a single dose. (wistar.org)
SOUTH SAN FRANCISCO, Calif., July 06, 2023 (GLOBE NEWSWIRE) - Vaxart, Inc. (Nasdaq: VXRT) today announced positive topline data from the dose-ranging Phase 2 clinical trial of its oral pill bivalent norovirus vaccine candidate. (itbusinessnet.com)
Results from this Phase 2 dose-ranging study also demonstrated that the bivalent norovirus vaccine candidate was well tolerated, with a favorable safety profile that included no vaccine-related serious adverse events (SAEs) and no dose limiting toxicity. (itbusinessnet.com)
The first 10 subjects received open label high-dose vaccine and the remaining subjects were randomized to high- or medium-dose vaccine (N=50 for each arm) or placebo (N=25). (itbusinessnet.com)
Comparing one dose of HPV vaccine in girls aged 9-14 years in Tanzania (DoRIS) with one dose of HPV vaccine in historical cohorts: an immunobridging analysis of a randomised controlled trial. (who.int)
Persons who administer vaccines should screen patients for contraindications and precautions to the vaccine before each dose of vaccine is administered ( Table 4-1 ). (cdc.gov)
Persons who experienced encephalopathy within 7 days after administration of a previous dose of pertussis-containing vaccine not attributable to another identifiable cause should not receive additional doses of a vaccine that contains pertussis ( 4, 5 ). (cdc.gov)

Vaxart, Inc. is a clinical-stage biotechnology company that is primarily focused on the development of oral recombinant vaccines based on its Vector-Adjuvant-Antigen Standardized Technology (VAAST) oral vaccine platform. (stockhouse.com)
In 2002, laboratory space, equipment and personnel were acquired and work on an HIV-1 vaccine development plan began. (wikipedia.org)
Commercial applications of this proprietary platform include the development of more effective vaccines. (globenewswire.com)
The iBioModulator platform can be used with any recombinant expression technology for vaccine development and production. (globenewswire.com)
Its development programs currently include tablet vaccines designed to protect against coronavirus, norovirus, seasonal influenza and respiratory syncytial virus (RSV), as well as a therapeutic vaccine for human papillomavirus (HPV), Vaxart's first immuno-oncology indication. (annualreports.com)
The data reported today support the continued development of Vaxart's oral norovirus vaccine candidate in adult populations and add to the growing body of evidence supporting its clinical utility. (itbusinessnet.com)
Vaxart, Inc, a clinical-stage biotechnology company, engages in the discovery and development of oral recombinant protein vaccines based on its proprietary oral vaccine platform. (defenseworld.net)
Increased government funding for vaccine development, increased investments by major market players, increasing disease prevalence, technological advances, and NGOs' initiatives are some of the factors driving the global therapeutic vaccines market forward. (marketdataforecast.com)
Vaccine R&D takes a long time and requires a lot of money, just like drug development. (marketdataforecast.com)
When the final product is approved for commercial use, a significant amount of money has been spent on the vaccine development R&D process. (marketdataforecast.com)
As the COVID-19 virus spreads worldwide, countries and medical regulators will speed up vaccine development. (marketdataforecast.com)
The development of peptide-based vaccines targeting group A streptococcus ( S. progenes ) is made difficult by the fact that there are over 200 different strains against which protection must be ensured. (moylelab.com)
Moyle PM, Olive C, Ho M-F, Pandey M, Dyer J, Suhrbier A, Fujita Y, Toth I. Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. (moylelab.com)

Over 270 million doses of the vaccines have been administered worldwide (as of May 2017). (cancer.org.au)

The intensity of T-cell response induced by the vaccine was correlated with clinical response. (aacrjournals.org)
GeoVax is a clinical-stage biotechnology company which develops vaccines. (wikipedia.org)
citation needed] GeoVax is currently conducting multiple site Phase 2 Human clinical trials for HIV/AIDS preventive vaccine products following successful completion of multiple Phase 1 human clinical trials. (wikipedia.org)
In 2010 GeoVax began enrolling patients in a Phase 1 therapeutic clinical trial for individuals already infected with HIV. (wikipedia.org)
HVTN 205 Study-In early 2009, the HVTN began enrolling patients in a preventive Phase 2 clinical trial sponsored by GeoVax Labs, Inc. This study is investigating a prime-boost approach using GeoVax's combination DNA/MVA vaccine. (wikipedia.org)
Clinical trials continue into different types of therapeutic vaccines. (canceraustralia.gov.au)
Vaxart is a clinical-stage biotechnology company developing a range of oral recombinant vaccines based on its proprietary delivery platform. (annualreports.com)
Clinical trials must be completed before a vaccine can be released commercially. (marketdataforecast.com)
Most vaccines are rejected at each stage of the clinical trial. (marketdataforecast.com)

At Day 29, increases in serum IgA, IgG, and BT50, for both the GII.4 and GI.1 strains in the vaccine arms, were similar to those seen in previous norovirus studies conducted by Vaxart. (itbusinessnet.com)
Topline data reported today further validate the potential of our norovirus vaccine candidate and, more broadly, our oral vaccine platform," said Dr. James F. Cummings, Vaxart's Chief Medical Officer. (itbusinessnet.com)
Today's results add to the evidence supporting the potential of this approach in addressing the unmet and critical need for an approved norovirus vaccine. (itbusinessnet.com)
These data, along with upcoming topline data from the ongoing Phase 2 G1.1 challenge study, will inform dosage amounts for a bivalent norovirus Phase 2b study, the next step in progressing the vaccine candidate. (itbusinessnet.com)

Severe Combined Immunodeficiency (SCID) disease and a history of intussusception are both contraindications to the receipt of rotavirus vaccines ( 6 ). (cdc.gov)

Do not administer live vaccines 30 days before or concurrently with belimumab. (medscape.com)
Severely immunocompromised persons generally should not receive live vaccines ( 3 ). (cdc.gov)

The DDMM regimen consists of priming with two doses of the pGA2/JS7 recombinant DNA vaccine and boosting with two doses of VA/HIV62B recombinant MVA vaccine. (wikipedia.org)
The MMM regimen consists of priming and boosting with a total of three doses of the recombinant MVA vaccine. (wikipedia.org)
Based on doses distributed in Australia, the current estimated risk of severe allergic reaction, anaphylaxis, is 2.6 in a million risk, which is why practitioners giving the vaccine have the necessary medical equipment and drugs on site. (cancer.org.au)

The mechanism by which vaccine adjuvants enhance immune responses has historically been considered to be the creation of an antigen depot. (mdpi.com)
Animal studies have shown that the iBioModulator platform can increase the strength of the immune response specific to a vaccine antigen (as measured by antibody titer). (globenewswire.com)

HPV6 may be the most prevalent low risk alpha-papillomavirus type and is commonly associated with genital warts [ 2 ]. (biomedcentral.com)

To date, there has been no vaccine to treat those already infected. (drwaynecottrell.com)

Human papillomavirus type-6 (HPV6) is the major etiological agent of anogenital warts both men and women. (biomedcentral.com)

We developed vaccines expressing the SARS -CoV-2 spike or nucleocapsid protein. (wistar.org)
The vaccine works with a combined DNA vaccine and MVA (modified vaccinia Ankara) vaccine both of which lead to the insertion of genes into primate DNA which leads to foreign protein expression. (wikipedia.org)
The patent (European patent EP 1664322) covers iBio's carrier molecule fusion protein technology (iBioModulator™) for therapeutic proteins and vaccines. (globenewswire.com)
About iBio, Inc. iBio develops and offers proprietary products and product licenses, based on its proprietary iBioLaunch™ and iBioModulator™ platforms, providing collaborators full support for turn-key implementation of its technology for protein therapeutics and vaccines. (globenewswire.com)

We are proposing to treat these patients with HPV vaccine with or without pembrolizumab during the window prior to surgery, in hopes of stimulating an immune response. (mayo.edu)

The company is now working on vaccines for Marburg, Lassa Fever, Ebola, Zika and Covid-19. (wikipedia.org)

In 2006, the US Food and Drug Administration (FDA) approved a vaccine for HPV types 6, 11, 16, and 18. (medscape.com)

Mrs. Capilla stated that Spanish Health Authorities have not recognized the adverse reactions - most of them serious- that affected girls suffered after receiving the HPV vaccine, even though the reactions they suffered are registered in the product leaflet and in numerous similar reports to the Spanish and European databases. (sanevax.org)
It is obvious: when different people, in different parts of the world, at different times react to a drug/vaccine in the same way, as is the case with HPV vaccines - something has to be wrong with the product in question - particularly when the Ministry has recognized this vaccine, like any medicine, causes adverse effects. (sanevax.org)
Recognize the adverse reactions (most of which are already registered in the leaflet of the product, the databases of European Countries, EEUU and scientific literature) and the status of victims of the HPV vaccine. (sanevax.org)

Much of the laboratory's efforts focus on developing a new preventative vaccine for rabies-a lethal and underestimated disease that remains a top public health priority across the globe-have yielded useful technologies that the Ertl laboratory is applying to combating other viruses. (wistar.org)

Anatomy9

Organisms16

Diseases19

Chemicals and Drugs86

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Psychiatry and Psychology3

Phenomena and Processes12

Anthropology, Education, Sociology and Social Phenomena3

Technology, Industry, Agriculture1

Information Science3

Named Groups1

Health Care13

Geographicals1

Cervical17

Vaccination14

Infection14

Cancers5

Infections10

Immunity8

Cancer36

Antigens3

Efficacy2

Preventive vaccines1

Gardasil5

20222

Quadrivalent HPV vaccine1

Lesions1

Bivalent vaccine1

Vectors3

Viral3

Candidates4

Influenza vaccine1

Prevention1

Company's1

Potency3

Mice6

Adenovirus1

Immunocompetent1

Candidate Vaccines1

Treatment4

Dose8

Development13

20171

Clinical9

Norovirus4

Rotavirus1

Live vaccines2

Doses3

Antigen2

Genital warts1

Already infected1

Anogenital1

Protein4

Immune response1

Ebola1

Types1

Adverse3

Rabies1