Cell Adhesion MoleculesSignal TransductionCell Line, TumorMolecular Targeted TherapyMolecular Sequence DataSmall Molecule LibrariesAmino Acid SequenceCell ProliferationMice, Inbred C57BLProtein BindingCells, CulturedApoptosisCell LineRNA, Small InterferingGene Expression Regulation, NeoplasticModels, MolecularRNA, MessengerMice, KnockoutDisease Models, AnimalBlotting, WesternBase SequenceImmunohistochemistryGene Expression ProfilingBinding SitesReverse Transcriptase Polymerase Chain ReactionModels, BiologicalAntibodies, MonoclonalMutationRNA InterferenceCell MovementUp-RegulationDrug Delivery SystemsCell AdhesionAntineoplastic AgentsGene Expression RegulationNeoplasmsMice, TransgenicLigandsGene Knockdown TechniquesProtein ConformationPhosphorylationMembrane ProteinsKineticsDrug DesignTransfectionAntigens, CDInflammationPeptidesCell SurvivalEnzyme InhibitorsNeural Cell Adhesion MoleculesGene ExpressionProtein Structure, TertiaryFlow CytometryMice, Inbred BALB CMice, NudeIntercellular Adhesion Molecule-1Recombinant ProteinsDown-RegulationMolecular StructureStructure-Activity RelationshipTumor Markers, BiologicalT-LymphocytesMembrane GlycoproteinsTumor Cells, CulturedCrystallography, X-RayProtein Kinase InhibitorsOligonucleotide Array Sequence AnalysisMicroRNAsXenograft Model Antitumor AssaysCytokinesTime FactorsPeptide FragmentsNeoplasm InvasivenessDNACarrier ProteinsCell MembraneDrug DiscoveryEnzyme ActivationDrug Evaluation, PreclinicalProteinsCell DifferentiationNeoplasm ProteinsRecombinant Fusion ProteinsNF-kappa BVascular Cell Adhesion Molecule-1Disease ProgressionMice, SCIDHistocompatibility Antigens Class IMolecular WeightLymphocyte ActivationTranscription FactorsPhenotypeTumor Necrosis Factor-alphaDose-Response Relationship, DrugGene SilencingHEK293 CellsNeural Cell Adhesion Molecule L1Breast NeoplasmsEscherichia coli