CytokinesDiatrizoate MeglumineDisease Models, AnimalTumor Necrosis Factor-alphaCurcuminMice, Inbred C57BLCells, CulturedNeurodegenerative DiseasesApoptosisInflammationDose-Response Relationship, DrugSignal TransductionTime FactorsRNA, MessengerRats, Sprague-DawleyCell SurvivalAnti-Inflammatory Agents, Non-SteroidalMice, Inbred BALB CTreatment OutcomeCell ProliferationCell LineCell Line, TumorBlotting, WesternEnzyme InhibitorsRats, WistarAntineoplastic AgentsInterleukin-6Interleukin-1Interferon-gammaInflammation MediatorsInterleukin-10Interleukin-4Interleukin-1betaTh2 CellsInterleukinsLipopolysaccharidesInterleukin-8ChemokinesTh1 CellsMacrophagesGene Expression RegulationMice, KnockoutInterleukin-12NF-kappa BMonocytesEnzyme-Linked Immunosorbent AssayInterleukin-13T-LymphocytesInterleukin-2Lymphocyte ActivationGranulocyte-Macrophage Colony-Stimulating FactorInterleukin-17Flow CytometryDendritic CellsReverse Transcriptase Polymerase Chain ReactionUp-RegulationLeukocytes, MononuclearImmunity, InnateReceptors, CytokineGene ExpressionCD4-Positive T-LymphocytesInterleukin-5Cell DifferentiationRecombinant ProteinsAntigens, CDTransforming Growth Factor betaInterleukin-18LungChemokine CCL2SpleenToll-Like ReceptorsInterleukin 1 Receptor Antagonist ProteinAnti-Inflammatory AgentsTh17 CellsCytokine Receptor gp130Membrane GlycoproteinsMacrophage ActivationToll-Like Receptor 4Coculture TechniquesInterleukin-1alphaReceptors, InterleukinBiological MarkersMice, TransgenicNeutrophilsOncostatin MImmunologic FactorsInterleukin-11Down-RegulationNitric Oxide Synthase Type IIAdjuvants, ImmunologicT-Lymphocyte SubsetsMacrophages, PeritonealReceptors, Interleukin-1Th1-Th2 BalanceInterleukin-15STAT3 Transcription FactorCD8-Positive T-LymphocytesCell DivisionEpithelial CellsT-Lymphocytes, Helper-Inducer