Therapeutic protein stability. Medical search. Frequent questions

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Anatomy11

Cell Line CHO Cells Cells, Cultured HEK293 Cells Cell Line, Tumor HeLa Cells COS Cells Cell Nucleus NIH 3T3 Cells Cytoplasm Fibroblasts

Organisms15

Dependovirus Cricetulus Plants, Genetically Modified Adenoviridae Lentivirus Tobacco Cricetinae Mice, Inbred C57BL Mice, Inbred BALB C Escherichia coli Saccharomyces cerevisiae Bacteriophage T4 Cercopithecus aethiops Animals, Domestic Clostridium botulinum type C

Diseases1

Genomic Instability

Chemicals and Drugs100

Recombinant Proteins Proteins Erythropoietin Biological Products Recombinant Fusion Proteins Drug Carriers Green Fluorescent Proteins Polyethylene Glycols Luminescent Proteins Factor VIII Proteasome Endopeptidase Complex Antibodies, Monoclonal Antibodies Ubiquitin beta-Galactosidase Guanidine Immunoglobulin G Ubiquitin-Protein Ligases Urea RNA, Messenger Muramidase Solvents Mutant Proteins Nuclear Proteins DNA-Binding Proteins Transcription Factors Leupeptins Bacterial Proteins Tumor Suppressor Protein p53 Proto-Oncogene Proteins c-mdm2 Amino Acids Salts Proteasome Inhibitors Lysine Serine F-Box Proteins Multiprotein Complexes RNA, Small Interfering Tumor Suppressor Proteins Solutions Ribonucleases Carrier Proteins Glycogen Synthase Kinase 3 Disulfides Lactalbumin Cysteine Complex Mixtures Cell Cycle Proteins Protein-Serine-Threonine Kinases Peptidylprolyl Isomerase Water Cullin Proteins Repressor Proteins Proto-Oncogene Proteins c-myc Membrane Proteins SUMO-1 Protein DNA Primers Hypoxia-Inducible Factor 1, alpha Subunit Apoproteins DNA Proline Ubiquitin-Specific Proteases Ubiquitins Alanine HSP90 Heat-Shock Proteins Molecular Chaperones Peptides Micrococcal Nuclease Trans-Activators SKP Cullin F-Box Protein Ligases Protein Isoforms Ribonuclease T1 Tryptophan RNA-Binding Proteins Multienzyme Complexes Histidine Protein Subunits Plant Proteins Cysteine Endopeptidases Methylamines Small Ubiquitin-Related Modifier Proteins beta-Transducin Repeat-Containing Proteins Peptide Hydrolases Escherichia coli Proteins Ligands Anilino Naphthalenesulfonates Hypoxia-Inducible Factor-Proline Dioxygenases Protein Synthesis Inhibitors Intracellular Signaling Peptides and Proteins Cycloheximide Threonine Proto-Oncogene Proteins Chymotrypsinogen Arabidopsis Proteins Cyclin-Dependent Kinase Inhibitor p21 Casein Kinase II Adaptor Proteins, Signal Transducing Sarcosine PTEN Phosphohydrolase Endopeptidases

Analytical, Diagnostic and Therapeutic Techniques and Equipment43

Protein Engineering Enzyme Stability Drug Stability Protein Footprinting Genetic Therapy Drug Delivery Systems Gene Transfer Techniques Protein Denaturation Models, Molecular Genetic Engineering Drug Carriers Transduction, Genetic Drug Design Circular Dichroism Mass Spectrometry Transfection Amino Acid Substitution Mutagenesis, Site-Directed Protein Unfolding Calorimetry, Differential Scanning Enzyme-Linked Immunosorbent Assay Models, Chemical Spectrometry, Fluorescence Crystallography, X-Ray Models, Biological Sequence Alignment Immunoprecipitation Blotting, Western Sequence Analysis, Protein Calorimetry Molecular Dynamics Simulation Two-Hybrid System Techniques Nuclear Magnetic Resonance, Biomolecular Immunoblotting Magnetic Resonance Spectroscopy Drug Storage Spectrophotometry, Ultraviolet Gene Knockdown Techniques Reverse Transcriptase Polymerase Chain Reaction Protein Interaction Mapping Electrophoresis, Polyacrylamide Gel Cloning, Molecular Precipitin Tests

Phenomena and Processes79

Protein Stability Immunogenetic Phenomena Enzyme Stability Genetic Vectors Protein Denaturation Thermodynamics Protein Folding Amino Acid Sequence Glycosylation Transduction, Genetic Transgenes RNA Stability Gene Expression Mutation Protein Conformation Ubiquitination Protein Structure, Tertiary Temperature Proteolysis Protein Structure, Secondary Protein Binding Transfection Plasmids Amino Acid Substitution Protein Unfolding Hot Temperature Half-Life Kinetics Protein Processing, Post-Translational Hydrogen Bonding Base Sequence Phosphorylation Hydrogen-Ion Concentration Binding Sites Transition Temperature Mutation, Missense Static Electricity Structure-Activity Relationship Amino Acid Motifs Transcription, Genetic Hydrophobic and Hydrophilic Interactions Gene Expression Regulation Signal Transduction Sequence Homology, Amino Acid Point Mutation Protein Structure, Quaternary Sumoylation Solubility Entropy Protein Multimerization Dimerization Time Factors Protein Transport Protein Biosynthesis Molecular Dynamics Simulation Down-Regulation Mutagenesis Cell Cycle Protein Interaction Domains and Motifs Genomic Instability Sequence Deletion Conserved Sequence Algorithms RNA Interference Phenotype Physicochemical Phenomena Molecular Structure Catalytic Domain Transcriptional Activation DNA Damage Cell Proliferation Apoptosis Promoter Regions, Genetic RNA Processing, Post-Transcriptional Surface Properties Substrate Specificity Catalysis Fluorescence Osmolar Concentration

Disciplines and Occupations6

Biotechnology Chemistry, Pharmaceutical Drug Design Chemistry, Physical Computational Biology Biophysics

Technology, Industry, Agriculture3

Biotechnology Nanoparticles Polyethylene Glycols

Information Science7

Molecular Sequence Data Amino Acid Sequence Base Sequence Computer Simulation Molecular Dynamics Simulation Algorithms Databases, Protein

Health Care2

Temperature Hot Temperature

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Protein Stability Immunogenetic Phenomena Protein Engineering Enzyme Stability Recombinant Proteins Drug Stability Protein Footprinting Genetic Vectors Genetic Therapy Proteins Drug Delivery Systems Gene Transfer Techniques Erythropoietin Biological Products Protein Denaturation Models, Molecular Molecular Sequence Data Recombinant Fusion Proteins Thermodynamics Genetic Engineering Protein Folding Biotechnology Dependovirus Drug Carriers Amino Acid Sequence Glycosylation Transduction, Genetic Nanoparticles Transgenes RNA Stability Cricetulus Plants, Genetically Modified Cell Line Gene Expression Green Fluorescent Proteins Polyethylene Glycols Mutation Protein Conformation Chemistry, Pharmaceutical Luminescent Proteins Factor VIII Drug Design Adenoviridae Lentivirus Ubiquitination Protein Structure, Tertiary Circular Dichroism Proteasome Endopeptidase Complex Mass Spectrometry Temperature CHO Cells Proteolysis Protein Structure, Secondary Protein Binding Tobacco Cricetinae Antibodies, Monoclonal Transfection Antibodies Ubiquitin Plasmids beta-Galactosidase Guanidine Amino Acid Substitution Mutagenesis, Site-Directed Protein Unfolding Cells, Cultured Immunoglobulin G Ubiquitin-Protein Ligases Mice, Inbred C57BL Calorimetry, Differential Scanning Hot Temperature Mice, Inbred BALB C Half-Life Kinetics Enzyme-Linked Immunosorbent Assay Protein Processing, Post-Translational Urea HEK293 Cells Hydrogen Bonding RNA, Messenger Muramidase Solvents Base Sequence Phosphorylation Hydrogen-Ion Concentration Binding Sites Escherichia coli Transition Temperature Mutation, Missense Models, Chemical Static Electricity Structure-Activity Relationship Cell Line, Tumor Mutant Proteins Amino Acid Motifs Nuclear Proteins Transcription, Genetic DNA-Binding Proteins Hydrophobic and Hydrophilic Interactions

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