AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and Equipment
PhotopheresisPUVA TherapyMethoxsalenDermatitis, ExfoliativeExtracorporeal CirculationSezary SyndromeImmunosuppressionLymphocyte SubsetsInfectionGraft vs Host Disease
ExtracorporealPlasmapheresisCutaneousLeukocytapheresisModalitiesPhlebotomyOrgan transplant rejectionClinicalTHERAKOSNovel therapeuticHematopoieticDepletionGVHDDonorTransfusionPatientsUltraviolet lightPlasmaTreatmentDisordersProcedureAcuteAlopeciaStemImmuneServicesInpatientUrgentLungDiseasesApplicationsPotentialCellsHospitalsManagementSearchConditionsProviderSystemTreat
Extracorporeal16
  • Photopheresis, also known as extracorporeal photopheresis, is a nonsurgical immunomodulatory therapy that collects and treats white blood cells from the blood using a machine. (utswmed.org)
  • Extracorporeal Photopheresis and Its Use in Dermatology While cutaneous T-cell lymphoma remains the only FDA approved use of extracorporeal photopheresis, it has potential as an off-label treatment for numerous dermatological conditions. (medscape.com)
  • Mallinckrodt plc (NYSE: MNK), a leading specialty pharmaceutical company, today announced the inaugural recipient of its Advancing Extracorporeal Photopheresis (ECP) Immunomodulation Investigator Award. (mallinckrodt.com)
  • Their proposal seeks to establish whether immunomodulation achieved through extracorporeal photopheresis (ECP) used in treatment of chronic graft-versus-host disease (GVHD) occurs through mediation of in vivo macrophage activation. (mallinckrodt.com)
  • The Patient Services unit performs therapeutic apheresis, therapeutic phlebotomy, and extracorporeal photopheresis. (uiowa.edu)
  • Introduction: Extracorporeal photopheresis (ECP) is a therapeutic method applied against some diseases such as cancers. (bvsalud.org)
  • It is a medical mystery why approaches such as extracorporeal ozone therapy or even photopheresis seem to have therapeutic effects in certain situations. (stemcellpatents.com)
  • In 2010, BOS stage 0-p was found, evolving to stage 1 in 2011 and leading to the introduction of montelukast and azithromycin, and extracorporeal photopheresis. (bmj.com)
  • The purpose of the experiments reported in this case report was to evaluate the need for clinical studies on such therapies, including epigenetic modulation and extracorporeal photopheresis. (diva-portal.org)
  • Dublin, Ireland, March 19, 2021 - A project that will analyze the immunomodulatory effects of extracorporeal photopheresis therapy (ECP) through innate cells has won Mallinckrodt plc's 2021 Advances in Immunomodulatory ECP research award. (mallinckrodt.com)
  • 13. Schwab L, Michel G, Bein G, Hackstein H (2020) CD71 surface analysis of T cells: a simple alternative for extracorporeal photopheresis quality control. (uni-giessen.de)
  • Extracorporeal photopheresis, an effective treatment for patients with chronic graft-vs-host disease, has recently been shown to benefit patients with steroid-refractory graft-vs-host disease. (ascopost.com)
  • Extracorporeal photopheresis inactivates antigen-presenting cells and T cells, whereas TNF antagonists decrease cellular activation and local tissue damage. (oncologynurseadvisor.com)
  • Russell-Jones R. Extracorporeal photopheresis in cutaneous T-cell lymphoma. (medscape.com)
  • Results: Since 2014, seventeen patients with GVHD were treated with ruxolitinib due to refractoriness to corticosteroids and immunosuppressants and a few to extracorporeal photopheresis, 8 with acute GVHD (1 pulmonary, 4 cutaneous grade IV and 3 digestive grade IV) and 9 with chronic GHVD (5 cutaneous sclerodermiform, 2 pulmonary and 1 multisystemic). (scielo.org)
  • Our renowned specialists offer extracorporeal photopheresis (ECP) for children who have developed graft-versus-host disease (GVHD) after receiving a bone marrow transplant. (ucsfbenioffchildrens.org)
Plasmapheresis1
  • Plasmapheresis is also employed for therapeutic use. (bvsalud.org)
Cutaneous4
  • Photopheresis has become a key component in the therapeutic armamentarium of cutaneous T-cell lymphoma, graft-versus-host disease following stem cell transplant, and allograft rejection of solid organs such as heart. (qxmd.com)
  • This unique therapeutic treatment option is used to treat the blood of patients with certain cancers of the skin such as Cutaneous T Cell Lymphoma and other disorders such as Graft vs Host Disease. (tulane.edu)
  • The focus of this laboratory is to determine whether these factors play a role in UV-induced immunosuppression and its long-lasting therapeutic effects on inflammatory conditions of the skin, including psoriasis and its comorbidities as well as neoplastic diseases such as cutaneous T-cell lymphoma. (cytokind.net)
  • Sézary syndrome: immunopathogenesis, literature review of therapeutic options, and recommendations for therapy by the United States Cutaneous Lymphoma Consortium (USCLC). (medscape.com)
Leukocytapheresis1
  • These health care providers are involved in the performance of therapeutic apheresis procedures including plasma exchange, red cell exchange, leukocytapheresis, plateletapheresis, photopheresis, LDL apheresis, and hematopoietic progenitor cell collection. (wikipedia.org)
Modalities1
  • The dermatology unit has individual rooms and therapeutic modalities such as ultraviolet light therapy, photopheresis, and hydrotherapy. (umiamihealth.org)
Phlebotomy1
  • Services provided by Vitalant physicians also include supervising hospital transfusion services and therapeutic blood-exchange procedures, overseeing therapeutic phlebotomy programs and helping deliver lifesaving cellular therapies collected by our staff and processed in our laboratories. (vitalant.org)
Organ transplant rejection1
  • Photopheresis in solid organ transplant rejection. (qxmd.com)
Clinical4
  • In addition, our physicians actively participate in multicenter clinical trials that focus on advancements such as using photopheresis for the treatment of lung transplant rejection. (utswmed.org)
  • The major activities of ASFA are member driven and educational, including publication of the Journal of Clinical Apheresis Special Issue: Clinical Applications of Therapeutic Apheresis: An Evidence Based Approach, publication of Principles of Apheresis Technology Textbook, publication of Therapeutic Apheresis: A Physician's Handbook, monthly apheresis educational webinar program and developing programming for the ASFA Annual Meeting. (wikipedia.org)
  • His clinical and research interests focus on photodermatology and photoimmunology, including phototherapy and photopheresis, photodermatoses, and photoprotection. (cytokind.net)
  • The provider's clinical rationale for selecting the hot or cold pack modality and its intended therapeutic benefits for the patient. (codingahead.com)
THERAKOS2
  • Mallinckrodt developed the Investigator Award to mark 30 years of its pioneering THERAKOS ECP Immunomodulation™ and it reflects the company's ongoing commitment to the science of immunomodulation through ECP and its therapeutic applications. (mallinckrodt.com)
  • Its Therakos therapeutic platforms, including the latest generation THERAKOS ® CELLEX ® Photopheresis System, are used by academic medical centres, hospitals, and treatment centres in more than 30 countries and have delivered more than 1 million treatments globally. (mallinckrodt.com)
Novel therapeutic1
  • This article is a summary of the European Society for Blood and Marrow Transplantation (EBMT) webinar entitled 'Pathophysiology of acute and chronic GvHD, novel therapeutic strategies in the preclinical phase' delivered by Ernst Holler on May 5th, 2020. (gvhdhub.com)
Hematopoietic1
  • Hematopoietic stem cell transplantation (HSCT) is an important therapeutic option for patients with non-malignant diseases as well as high-risk and refractory hematopoietic malignancies. (haematologica.org)
Depletion1
  • Therapeutic apheresis includes: plasma exchange, red cell exchange, platelet and leukocyte depletion and photopheresis. (rwjbh.org)
GVHD1
  • However, the GVHD mortality remains high in refractory patients, showing that better therapeutic strategies are needed. (scielo.org)
Donor2
  • The SHS was formed by nursing and allied health personnel, who were responsible for performing the donor and therapeutic procedures and operating the various blood cell separators. (wikipedia.org)
  • It was originally developed for the purpose to present scientific research on donor and therapeutic apheresis topics. (wikipedia.org)
Transfusion2
  • The therapeutic apheresis consultation and procedure is performed by Transfusion Medicine physicians, who are specialists in apheresis therapy. (rwjbh.org)
  • The transfusion medicine physician gives the orders required for the therapeutic pheresis procedure. (rwjbh.org)
Patients6
  • UT Southwestern performs photopheresis, the collection and treatment of white blood cells, for patients in the Dallas-Fort Worth area and beyond. (utswmed.org)
  • Therapeutic apheresis is performed on patients with a variety of medical disorders. (fmcna.com)
  • Robert Wood Johnson University Hospital (RWJUH) New Brunswick, through the NBAH Blood Center, provides therapeutic apheresis to inpatients, and patients admitted for one day stay. (rwjbh.org)
  • In this review, the reader will learn more about the history of photopheresis and how it became a therapeutic alternative for patients with solid organ transplants. (qxmd.com)
  • This position is a unique opportunity to provide 1-on-1 care to patients in a specialty area (Therapeutic Apheresis). (hirelatinos.org)
  • Thrombotic Thrombocytopenic Purpura (TTP) - For patients with suspected TTP / Microangiopathic Haemolytic Anaemia (MAHA) please contact Haematology at the Royal Liverpool University Hospital for advice and access to therapeutic apheresis if required. (blood.co.uk)
Ultraviolet light1
  • Photopheresis combines a photochemical reaction using ultraviolet light with apheresis to treat certain conditions, most commonly involving the immune system. (txbi.org)
Plasma3
  • During photopheresis, small amounts of blood are gradually removed through an inserted needle or central line catheter and circulated through a machine that separates the blood into red cells, white cells, platelets, and plasma. (utswmed.org)
  • Therapeutic plasma exchange removes plasma components from blood. (msdmanuals.com)
  • This market is driven by the advantages of apheresis collection over the whole blood collection, huge demand for plasma in plasma fractionation, and research for new applications of therapeutic apheresis. (micromarketmonitor.com)
Treatment5
  • In the list below you will find the most common diagnoses where therapeutic apheresis treatment is used. (fmcna.com)
  • Your healthcare team will prepare you for what to expect from the therapeutic apheresis treatment when it is prescribed. (fmcna.com)
  • Therapeutic apheresis is a complex treatment requiring careful administration to guarantee safety and efficacy. (rwjbh.org)
  • The application of therapeutic apheresis for pediatric treatment is an unexplored market and represents a prospective opportunity in the future. (micromarketmonitor.com)
  • Therapeutic response has been beneficial and resulted in successful treatment of these diseases. (oncologynurseadvisor.com)
Disorders1
  • The Photopheresis Unit uses photosensitizing chemicals referred to as psoralens and UVA light to treat the blood of individuals affected with certain skin disorders. (tulane.edu)
Procedure3
Acute1
  • Ensuring that the calcineurin inhibitor used for graft-vs-host disease prophylaxis is within the serum therapeutic range, or restarting a systemic calcineurin inhibitor along with high-dose systemic steroids at the onset of stage II to IV acute graft-vs-host disease is preferred. (ascopost.com)
Alopecia1
  • Evolving Story of JAK Inhibitors for Treating Alopecia Areata Review the introduction of Janus kinase inhibitors and their application as the first-line therapeutic option for severe alopecia areata. (medscape.com)
Stem2
  • Indeed, the exosomes derived from mesenchymal stem cells can represent the same therapeutic potential as parent cells with fewer side effects. (bvsalud.org)
  • Over the past years, stem cell technology was heralded as a significant breakthrough of the century in scrutinizing the intricacies of human body biology and discovering different therapeutic approaches. (bvsalud.org)
Immune1
  • In other diseases, the white cells are responsible for an immune response, and photopheresis aims to diminish this response. (utswmed.org)
Services1
  • OBI is the largest provider of therapeutic apheresis in the state and actively services 18 hospitals in the Oklahoma City and Tulsa areas. (txbi.org)
Inpatient1
  • Therapeutic apheresis procedures can be performed in both the hospital (inpatient) and outpatient setting, depending on the condition. (fmcna.com)
Urgent1
  • Thus, it is urgent to develop therapeutic strategies to face the SARS-CoV-2 viral infection at the severe stage. (medsci.org)
Lung1
  • DI-087 Restrictive allograft syndrome in lung transplantation: nintedanib as a new therapeutic strategy? (bmj.com)
Diseases1
  • Adipose tissue, especially brown type, is considered an attractive cell source for various therapeutic purposes, such as restoring damaged tissue or fighting against diseases such as obesity. (bvsalud.org)
Applications1
  • Part of the Company's ongoing commitment to the science of immunomodulation through ECP across therapeutic applications, the initiative was designed to recognize individuals and institutions whose research contributes to the advancement of knowledge in this broad area of medicine. (mallinckrodt.com)
Potential1
  • Dendritic cells-based therapeutic approach may be a potential strategy for SARS-CoV-2 infection. (medsci.org)
Cells1
  • One possibility is that stressing of cells outside of the body causes formation of apoptotic bodies, with the apoptotic bodies having a therapeutic effect.The possibility of apoptotic bodies mediating. (stemcellpatents.com)
Hospitals1
  • We are the largest therapeutic apheresis provider in the U.S., working with more than 450 hospitals and providing over 30,000 treatments. (fmcna.com)
Management2
  • How should therapeutic management be approached for each specific subtype? (medscape.com)
  • Further studies have to be conducted to assess the place of antifibrotic agents in RAS therapeutic management. (bmj.com)
Search1
  • An extensive literature search will highlight the evidence-based benefits of photopheresis (or lack thereof). (qxmd.com)
Conditions1
  • The benefit of photopheresis for people with autoimmune conditions like Crohn's disease is currently being studied. (txbi.org)
Provider1
  • Contact your tertiary provider for haemato-oncology for advice and access to therapeutic apheresis if required. (blood.co.uk)
System1
  • Drug delivery system is a method in which the therapeutic substances are delivered through general route of administration to obtain the therapeutic effect in humans or animals. (coherentmarketinsights.com)
Treat1
  • RAS therapeutic strategy is not clearly defined, but several cases reported the use of antifibrotic agents, indicated in idiopathic pulmonary fibrosis (IPF), to treat RAS, such as pirfenidone. (bmj.com)