• But it is perhaps not auspicious to quote him for purposes of the scientific debates on human cloning, because Ramsey agreed with and supported the scientific myth of the "pre-embryo" 47 made famous by Jesuit Richard McCormick and frog embryologist Clifford Grobstein. (lifeissues.net)
  • Thus, while Ramsey agreed that there is a human being present immediately at fertilization, he did not agree that it was also a human embryo or a human person - the classic "pre-embryo" argument. (lifeissues.net)
  • The human embryo did not begin until after 14-days, thus the above quote from Saunders would not apply. (lifeissues.net)
  • Perhaps Ramsey would give other extraordinarily powerful arguments as to why human cloning is unethical, but he obviously would not be able to base it on his unscientific "pre-embryo" position. (lifeissues.net)
  • 6. " ... any living human embryo has the inherent 'potential' to develop into a healthy baby . (lifeissues.net)
  • Originally the relevant philosophical term was "potency" (or inherent power or capacity conveyed by a specific nature) was used to apply to an already existing substance - such as a new living human embryo. (lifeissues.net)
  • In that sense, the human embryo would not be even a human being yet, much less a human person. (lifeissues.net)
  • Thus if by "potential" one means "potency" - i.e., that the early human embryo already exists with a human nature that is already there, and has its own inherent power or capacity (provided by that human nature) to simply grow bigger and bigger through all the usual developmental stages through birth, then such a statement stands as accurate - both scientifically and philosophically. (lifeissues.net)
  • That is, it would be acknowledging that the human embryo and the human " baby " are the same human being and human person throughout all of his/her development. (lifeissues.net)
  • On the other hand, if by "potential" one means that the human embryo is not a human being or human person yet , but might be later once it has been born (i.e., a "baby"), then that statement is both scientifically and philosophically incorrect. (lifeissues.net)
  • Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
  • Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
  • In this case, each embryo was created by taking a nucleus from a skin cell (donated by Wood and a colleague) and inserting it into a human egg from which the nucleus had been removed. (wikipedia.org)
  • It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
  • Assisted reproductive technology (ART) and embryo research have posed many challenges to the different timeframes of science, ethics and law. (edu.au)
  • Although the efficiency of nuclear transfer has been dramatically improved from the initial success rate of one live clone born from 277 embryo transfers [ 1 ], none of the aforementioned efforts abolished the common problems associated with nuclear transfer. (biomedcentral.com)
  • In January 2008, Dr. Andrew French and Samuel Wood of the biotechnology company Stemagen announced that they successfully created the first five mature human embryos using SCNT. (wikipedia.org)
  • The recent desperation to clone human embryos may be seriously undermining accepted ethical principles of medical research, with potentially profound wider consequences. (lifeissues.net)
  • Stem cells may be derived from adult tissues but the most potent are extracted from developing human embryos. (edu.au)
  • Currently, the efficiency for nuclear transfer is between 0-10%, i.e., 0-10 live births after transfer of 100 cloned embryos. (biomedcentral.com)
  • In 2004 and 2005, Hwang Woo-suk, a professor at Seoul National University, published two separate articles in the journal Science claiming to have successfully harvested pluripotent, embryonic stem cells from a cloned human blastocyst using SCNT techniques. (wikipedia.org)
  • A blastocyst (cloned or not), because it lacks any trace of a nervous system, has no capacity for suffering or conscious experience in any form - the special properties that, in our view, spell the difference between biological tissue and a human life worthy of respect and rights. (wikiquote.org)
  • The blastocyst can then be transferred to a recipient (h) and cloned animals are born after completion of gestation (i). (biomedcentral.com)
  • Two common methods of therapeutic cloning that are being researched are somatic-cell nuclear transfer and (more recently) pluripotent stem cell induction. (wikipedia.org)
  • With the cloning of a sheep known as Dolly in 1996 by somatic cell nuclear transfer (SCNT), the idea of human cloning became a hot debate topic. (wikipedia.org)
  • Four embryonic stem cell lines from human fetal somatic cells were derived from those blastocysts. (wikipedia.org)
  • Cloning by nuclear transfer using mammalian somatic cells has enormous potential application. (biomedcentral.com)
  • However, somatic cloning has been inefficient in all species in which live clones have been produced. (biomedcentral.com)
  • These developmental defects have been attributed to incomplete reprogramming of the somatic nuclei by the cloning process. (biomedcentral.com)
  • Because cattle are a species widely used for nuclear transfer studies, and more laboratories have succeeded in cloning cattle than any other specie, this review will be focused on somatic cell cloning of cattle. (biomedcentral.com)
  • Somatic cell cloning (cloning or nuclear transfer) is a technique in which the nucleus (DNA) of a somatic cell is transferred into an enucleated metaphase-II oocyte for the generation of a new individual, genetically identical to the somatic cell donor (Figure 1 ). (biomedcentral.com)
  • Schematic diagram of the somatic cloning process. (biomedcentral.com)
  • Developmental defects, including abnormalities in cloned fetuses and placentas, in addition to high rates of pregnancy loss and neonatal death have been encountered by every research team studying somatic cloning. (biomedcentral.com)
  • In 2011, scientists at the New York Stem Cell Foundation announced that they had succeeded in generating embryonic stem cell lines, but their process involved leaving the oocyte's nucleus in place, resulting in triploid cells, which would not be useful for cloning. (wikipedia.org)
  • Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
  • Finally, and inexorably, a true professional scientist poses clearly challenging questions to his research colleagues, and to the scientific enterprise in general, about the dubious "scientific" justification for the current rush to clone human beings - for both "therapeutic" and for "reproductive" purposes. (lifeissues.net)
  • The report arose out of a recommendation for the Committee to review the report of the Australian Health Ethics Committee (AHEC) of the NHMRC entitled Scientific, Ethical and Regulatory Considerations Relevant to Cloning of Human Beings (hereafter the AHEC Report ). (edu.au)
  • In his speech on "Biological Possibilities for the Human Species of the Next Ten Thousand Years" at the Ciba Foundation Symposium on Man and his Future in 1963, he said: It is extremely hopeful that some human cell lines can be grown on a medium of precisely known chemical composition. (wikipedia.org)
  • Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
  • In this experiment, the researchers developed a protocol for using SCNT in human cells, which differs slightly from the one used in other organisms. (wikipedia.org)
  • is a British developmental biologist who was the first to use nuclear transfer of differentiated adult cells to generate a mammalian clone, a Finn Dorset sheep named Dolly, born in 1996. (mathisfunforum.com)
  • These ethical concerns have prompted several nations to pass laws regarding human cloning. (wikipedia.org)
  • This issue was considered by the House of Representatives Standing Committee on Legal and Constitutional Affairs in its report entitled Human Cloning: Scientific, Ethical and Regulatory Aspects of Human Cloning and Stem Cell Research (hereafter the Andrews Report , after the Chair of the Committee, Mr Kevin Andrews, MP) released in September 2001. (edu.au)
  • The term is generally used to refer to artificial human cloning, which is the reproduction of human cells and tissue. (wikipedia.org)
  • Therapeutic cloning would involve cloning cells from a human for use in medicine and transplants. (wikipedia.org)
  • Reproductive cloning would involve making an entire cloned human, instead of just specific cells or tissues. (wikipedia.org)
  • Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
  • Ethically, since eventually all such "research" will be applied to people, he cautions against the abuse of women "egg" donors, and against the premature use of vulnerable sick human patients for testing supposedly "patient-specific" stem cells in supposed "therapies", pointing to the obvious violations of standard international research ethics guidelines such clinical trials would necessarily entail. (lifeissues.net)
  • As he has questioned the HFEA before, would not the use of vulnerable human patients in clinical trials be premature, dangerous, and unethical given the already acquired knowledge in the research community that such supposed "patient-specific" stem cells would most probably cause serious immune rejection reactions in these patients? (lifeissues.net)
  • The unique properties of human stem cells have aroused considerable optimism about their potential as new pathways for alleviating human suffering caused by disease and injury. (edu.au)
  • Tumor development has been said to occur in three distinct steps: inefficient elimination of early transformed cells, development of a state of equilibrium between tumor cells and immune cells, and tumor escape from immune pressure ( 2 ). (frontiersin.org)
  • Indeed a wealth of studies from humans and mouse models establishes a particularly potent role for CD8 T cells in controlling the outgrowth of malignancies ( 3 ). (frontiersin.org)
  • The upper portion of the female reproductive tract consists of the fallopian tubes, uterus body, and endocervix, which has columnar epithelial cells and is distincted from ectocervix which is part of the lower tract characterized by squamous epithelial cells [ 4 , 6 ]. (hindawi.com)
  • Stem cell transplantation is a promising strategy for therapeutic cardiac regeneration, but current therapies are limited by inefficient interaction between potentially beneficial cells (either exogenously transplanted or endogenously recruited) and the injured tissue. (regenerativemedicine.net)
  • Iron nanoparticles are conjugated with two types of antibodies (one against antigens on therapeutic cells and the other directed at injured cells) to produce magnetic bifunctional cell engager (MagBICE). (regenerativemedicine.net)
  • The antibodies link the therapeutic cells to the injured cells, whereas the iron core of MagBICE enables physical enrichment and imaging. (regenerativemedicine.net)
  • But he is equally concerned about the unethical aspects inherent in the rush to perform " therapeutic " human cloning research, including the abuses to all vulnerable human patients who would be required to participate in clinical trials. (lifeissues.net)
  • Human cloning is the creation of a genetically identical copy of a human. (wikipedia.org)
  • In biology , cloning is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria , insects or plants reproduce asexually . (wikiquote.org)
  • The possibilities of human cloning have raised controversies. (wikipedia.org)
  • And he also agrees that if we don't find global agreement on human cloning, "we can probably expect dire consequences for the future of biomedical research and its impact on society at large. (lifeissues.net)
  • And no mention of long-term risks of infertility and reproductive cancers. (billmuehlenberg.com)
  • Characterized by cell-surface molecules including CD103, CD69, and CD49a, T RM -like tumor-infiltrating lymphocytes (TILs) can be found in a wide range of human cancers, where they portend improved prognosis. (frontiersin.org)
  • I knew and had great respect for the famous Protestant theologian and bioethicist Paul Ramsey, and used much of his work concerning the use of human subjects in research in my own. (lifeissues.net)
  • Other proposals have been suggested: "Liberal MP Mal Washer said we could use leftover eggs from IVF, but all the research showed that cloning with left over eggs was not realistic. (billmuehlenberg.com)
  • This discovery will likely have a tremendous impact on the research conducted in the field of HIV cure both at basic and therapeutic approaches. (europa.eu)
  • In 1966, his final year at Nottingham, he received a scholarship to conduct research for a summer under English biologist Ernest John Christopher Polge in the Unit of Reproductive Physiology and Biochemistry, then a division of the Agricultural Research Council at the University of Cambridge. (mathisfunforum.com)
  • Although the possibility of cloning humans had been the subject of speculation for much of the 20th century, scientists and policymakers began to take the prospect seriously in 1969. (wikipedia.org)
  • Many nations outlawed it, while a few scientists promised to make a clone within the next few years. (wikipedia.org)
  • The two cloning bills before the Senate] say scientists can use animal eggs. (billmuehlenberg.com)
  • But in countries such as Britain, where there is cloning, scientists say they want fresh eggs from young women. (billmuehlenberg.com)
  • This would have been the first major breakthrough in human cloning. (wikipedia.org)
  • In addition to low success rates, cloned animals tend to have more compromised immune function and higher rates of infection, tumor growth, and other disorders. (wikiquote.org)
  • Hormones regulate the immune system throughout the female reproductive tract in a way that favors conditions for sperm migration, fertilization, implantation, and pregnancy [ 16 , 17 ]. (hindawi.com)
  • Even if you don't have a religious view of the sanctity of life, you have to ask is there going to be a massive trade in human eggs from poor women to rich countries. (wikiquote.org)
  • Entitled, "Not enough eggs in cloning basket," she warned how women would especially suffer if cloning is given the green light. (billmuehlenberg.com)
  • Says George, "Cloning depends on a continuous supply of fresh human eggs and without eggs cloning is impossible. (billmuehlenberg.com)
  • Therapeutic cloning has been described as a wildly inefficient process requiring hundreds of eggs to produce just a single clone. (billmuehlenberg.com)
  • The same is true in the cloning debate. (billmuehlenberg.com)
  • Agreeing with the premise of an earlier article in the same journal, he agrees that we "must not let our debate get completely derailed by vested interests, whether politically or economically motivated", and that the failure to find global agreement on human cloning at the U.N. could result in "reproductive" human cloning [and all the abuses of women that would entail]. (lifeissues.net)
  • and the general public debate about reproductive cloning. (edu.au)
  • a) It would seem that Saunders uses the "potential" argument here quite appropriately, but it is critical that the term be understood properly in order to deflect any misunderstandings or misinterpretations - especially if the term were to be used in any U. N. treaty on human cloning. (lifeissues.net)
  • If the term "potential" were to be incorporated into a U. N. treaty on human cloning, it would be necessary to clarify its use as referring to an already existing human being/person. (lifeissues.net)
  • Another Nobel Laureate, James D. Watson, publicized the potential and the perils of cloning in his Atlantic Monthly essay, "Moving Toward the Clonal Man", in 1971. (wikipedia.org)
  • Cloning advocates have failed to show that you can get ova without harming women. (billmuehlenberg.com)
  • Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)
  • J. B. S. Haldane was the first to introduce the idea of human cloning, for which he used the terms "clone" and "cloning", which had been used in agriculture since the early 20th century. (wikipedia.org)
  • The first hybrid human clone was created in November 1998, by Advanced Cell Technology. (wikipedia.org)
  • Stem cell technology in humans derives from earlier and complementary work in animal studies. (edu.au)
  • Nobel Prize-winning geneticist Joshua Lederberg advocated cloning and genetic engineering in an article in The American Naturalist in 1966 and again, the following year, in The Washington Post. (wikipedia.org)
  • Review of Critical Article: Cobbe, 'Why the apparent haste to clone humans? (lifeissues.net)
  • Two commonly discussed types of human cloning are therapeutic cloning and reproductive cloning. (wikipedia.org)
  • Since the term "born" has been used as an essential part of the definition of " reproductive cloning " used by Weissman, the National Academy of Sciences, etc., then it is critical to use the accurate term with the proper meaning. (lifeissues.net)
  • a) Note, again, the reference to only sexual human reproduction - "the moment of conception" - i.e., fertilization. (lifeissues.net)
  • It has not yet been " ensouled " - and so is not yet a " person " - i.e., a human subject to be protected from abuse in experimentation. (lifeissues.net)
  • The commercialisation of human life will continue, as sure as night follows day. (billmuehlenberg.com)
  • Agriculture plays a vital role supporting human life on Earth but faces significant challenges to feed the growing population. (cshlpress.org)
  • More than 90% of cloning attempts fail to produce viable offspring. (wikiquote.org)
  • More than 100 nuclear transfer procedures could be required to produce one viable clone. (wikiquote.org)
  • Perhaps the first step will be the production of a clone from a single fertilized egg, as in Brave New World. (wikipedia.org)
  • 7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)
  • A complete ban on all forms of human cloning is the only way we can ensure that the Frankenstein scenarios being warned about do not become realities. (billmuehlenberg.com)
  • This is contrary to humans, where VHL-1 mutations cause a disease characterized by angiomas, renal carcinomas and various other tumors as a direct result of aberrant HIF-1 activation. (uw.edu)