Therapeutic arthritis experimental. Medical search. Frequent questions

Optimal care of patients with rheumatoid arthritis (RA) consists of an integrated approach that includes both pharmacologic and nonpharmacologic therapies. (medscape.com)
The present study proves the anti-inflammatory/anti-oxidant activity of turmeric over ginger and indomethacin, which may have beneficial effects against rheumatoid arthritis onset/progression as shown in AIA rat model. (nih.gov)
OBJECTIVE: Rheumatoid arthritis (RA) is an autoimmune disease caused by loss of immunologic self tolerance and characterized by chronic joint inflammation. (unicatt.it)
A combination of glucosamine, chondroitin and quercetin significantly improve the symptoms of osteoarthritis and rheumatoid arthritis. (greenmedinfo.com)
A fermented wheat germ extract significantly improves patients with severe rheumatoid arthritis. (greenmedinfo.com)
An elemental diet for 2 weeks is as effective as prednisone in improving symptoms of active rheumatoid arthritis. (greenmedinfo.com)
Bee venom has both a synergist and drug sparing effect when combined with drugs in the treatment of rheumatoid arthritis. (greenmedinfo.com)
Blackcurrant seed oil is a potentially effective treatment for active rheumatoid arthritis. (greenmedinfo.com)
Cats claw (Uncaria tomentosa) has therapeutic value in patients with active rheumatoid arthritis. (greenmedinfo.com)
Cod liver oil (omega-3 Fatty Acids) reduces the need for NSAIDs in patients with rheumatoid arthritis. (greenmedinfo.com)
Cod liver oil is safe and efficacious in the treatment of rheumatoid arthritis. (greenmedinfo.com)
Rheumatoid arthritis (RA) is characterized by chronic inflammation of the synovial tissue, joint dysfunction, and damage. (nih.gov)
For example, if the cause of bone marrow edema is rheumatoid arthritis, the edema is attributed to the penetration sites caused by the resorption of mineralized cortical bone beneath articular cartilage. (wikipedia.org)
Anti-TNF treatment response in rheumatoid arthritis patients is associated with genetic variation in the NLRP3-inflammasome. (cdc.gov)
Enhanced activity of NLRP3 inflammasome in peripheral blood cells of patients with active rheumatoid arthritis. (cdc.gov)
Genetic Variants of the NLRP3 Inflammasome Are Associated with Stroke in Patients with Rheumatoid Arthritis. (cdc.gov)
Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis. (cdc.gov)
Influence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in rheumatoid arthritis. (cdc.gov)
Confirmation of an IRAK3 polymorphism as a genetic marker predicting response to anti-TNF treatment in rheumatoid arthritis. (cdc.gov)
Girls whose parents smoked cigarettes were 75 percent more likely to develop rheumatoid arthritis as adults, according to a study funded by the NIAMS, other NIH Institutes, and the Rheumatology Research Foundation. (nih.gov)
In rheumatoid arthritis, t-VNS resulted in reductions in disease activity, CRP, interferon- γ , and interleukin-10 [ 26 ], but hitherto, such transcutaneous devices have not been explored in the treatment of PsA or AS. (hindawi.com)
It has been known for more than three decades that individuals with a particular version of a gene -- human leukocyte antigen (HLA) -- have an increased risk for rheumatoid arthritis. (domain-b.com)
Meanwhile, in recent years, there has been a growing interest in the relationship between rheumatoid arthritis and environmental factors, such as cigarette smoking. (domain-b.com)
In smokers who develop rheumatoid arthritis, the disease hits harder. (domain-b.com)
Cigarettes are one of the top environmental concerns with rheumatoid arthritis. (domain-b.com)
We've shown in this study that the interaction between dioxin and the HLA gene variant activates events known to be associated with rheumatoid arthritis. (domain-b.com)
Bone degeneration in rheumatoid arthritis is caused by hyperactivity of certain bone cells called osteoclasts, which absorb bone tissue. (domain-b.com)
Currently, the treatments available for rheumatoid arthritis focus primarily on the inflammation but do not directly target bone destruction, says Holoshitz. (domain-b.com)
These drugs almost completely inhibit experimental rheumatoid arthritis and bone damage in mice. (domain-b.com)
Complicated, accelerated, and acute silicosis are frequently accompanied by mycobacterial infections and autoimmune diseases such as scleroderma and rheumatoid arthritis. (cdc.gov)
Comprising multiple disorders and symptoms ranging from organ-specific to systemic, autoimmune diseases include insulin-dependent diabetes mellitus, rheumatoid arthritis, systemic lupus erythematosus, scleroderma, thyroiditis, and multiple sclerosis. (nih.gov)
Findings may offer insight to effective treatments for inflammatory diseases, such as rheumatoid arthritis, psoriasis, and multiple sclerosis. (nih.gov)
Stained sections of foot joints from wild-type (left) and TTP+ (right) mice show that when both were tested using a model of rheumatoid arthritis, the wild-type mouse experienced significant inflammation. (nih.gov)
The results suggest that pharmaceutical compounds or other therapeutic methods that produce elevated levels of TTP in humans may offer an effective treatment for some inflammatory diseases, such as rheumatoid arthritis, psoriasis, and multiple sclerosis. (nih.gov)
The mice were then tested using experimental models of rheumatoid arthritis, psoriasis, and multiple sclerosis. (nih.gov)
Using the rat adjuvant arthritis (AA) model of human rheumatoid arthritis, we determined whether the ethanol extract of Celastrus aculeatus Merr. (biomedcentral.com)
On the basis of our results, we suggest further systematic exploration of Celastrus as an adjunct therapeutic modality for rheumatoid arthritis. (biomedcentral.com)
In particular, one hundred and six post-menopausal women with rheumatoid arthritis (RA) and 119 age-matched healthy controls were prospectively enrolled in order to compare the two groups in terms of bone parameters and to observe the influence of body composition on bone mineral density (BMD) and osteoporosis outcomes. (echolightmedical.com)
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease which affects the joints. (fapesp.br)
For many patients, the cervical spine is associated with rheumatoid arthritis. (nih.gov)
The cervical spine has been reported to be associated with patients with rheumatoid arthritis [1-6]. (nih.gov)
These proinflammatory cytokines have been implicated in the pathogenesis of some autoimmune diseases, including rheumatoid arthritis (RA), psoriasis, and atopic dermatitis. (aai.org)
Bioelectronic medicine sends similar electrical signals to nerves in our body to treat a wide variety of diseases, such as epilepsy, heart failure, rheumatoid arthritis, and obesity. (nih.gov)
OBJECTIVE: The role of plasmacytoid dendritic cells (PDCs) and type I interferons (IFNs) in rheumatoid arthritis (RA) remains a subject of controversy. (cnrs.fr)
Bingham III, C.O. (2002) The pathogenesis of rheumatoid arthritis: Pivotal cytokines involved in bone degradation and inflammation. (scirp.org)
Tang, L.L., Gao, J.S., Chen, X.R. and Xie, X. (2006) Inhibitory effect of resveratrol on the proliferation of synoviocytes in rheumatoid arthritis and its mechanism in vitro. (scirp.org)
Uveitis has a wide variety of causes, including eye injury, cancer, infection, and autoimmune diseases such as rheumatoid arthritis and multiple sclerosis. (melatonina.it)
OBJECTIVES: To establish if changes in Th1/Th17 cell populations previously reported in experimental arthritis occur in patients with rheumatoid arthritis (RA) treated with anti-tumour necrosis factor α (TNFα) agents, and whether the therapeutic response to anti-TNFα is compromised in patients and mice because of elevated Th17/IL-17 levels. (ox.ac.uk)
SAN FRANCISCO--( BUSINESS WIRE )-- Galvani Bioelectronics , a clinical-stage company formed through a strategic partnership between GlaxoSmithKline (GSK) and Verily Life Sciences (Verily) in 2016 with the aim to develop targeted neuromodulation therapies, today announced that the first patient with Rheumatoid Arthritis (RA) has been treated through stimulation of the splenic nerve using its novel bioelectronics platform. (biospace.com)
We look forward to bringing the wide-ranging potential of splenic nerve stimulation to the clinic as a hopeful new treatment option for people suffering with rheumatoid arthritis," said Stephen Gillett, President and COO of Verily and Galvani Board Director. (biospace.com)
The David Z. Rosensweig Genomics Research Center is applying genomic approaches to understand the causes and mechanisms of musculoskeletal and inflammatory conditions, including rheumatoid arthritis, osteoarthritis, tendon degeneration and associated muscle weakness, and bone loss in osteoporosis and orthopaedic implant loosening. (hss.edu)
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. (hss.edu)
Machine learning integration of rheumatoid arthritis synovial histology and RNAseq data identifies three disease subtypes. (hss.edu)
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. (hss.edu)
Rheumatoid arthritis (RA) is an inflammatory and systemic autoimmune disease that affects peripheral joints leading to joint degradation, pain, deformities, decreased activities of daily living, and sedentary lifestyle, resulting in secondary sarcopenia. (jpccr.eu)
Casanova-Vallve N, Constantin-Teodosiu D, Filer A, Hardy RS, Greenhaff PL, Chapman V. Skeletal muscle dysregulation in rheumatoid arthritis: Metabolic and molecular markers in a rodent model and patients. (jpccr.eu)
Skeletal muscle redox signaling in rheumatoid arthritis. (jpccr.eu)
Management of fatigue in rheumatoid arthritis. (jpccr.eu)
IMPORTANCE: Accumulating evidence suggests that IL-17 A has broad pathogenic roles in multiple autoimmune and immune-mediated inflammatory diseases, including psoriasis and rheumatoid arthritis (RA). (ru.nl)
OBJECTIVES: This review aims to summarize the current preclinical evidence on the role of Th17 cells and IL-17 and related cytokines in immune-mediated disease pathophysiology, with a focus on psoriasis and rheumatoid arthritis, as well as to summarize recent clinical trials in these indications with newly developed IL-17 pathway inhibitors. (ru.nl)
Furthermore, some researchers have suggested that toxic overload may contribute to autoimmune diseases including inflammatory and rheumatoid arthritis, 6,7 and neurological diseases such as Alzheimer's and Parkinson's. (totalhealthmagazine.com)

To compare the nitric oxide synthase (NOS) inhibitors NG-methyl-L-arginine (L-NMA) and aminoguanidine (AG) as prophylactic and therapeutic agents in rat adjuvant induced arthritis (AIA). (elsevierpure.com)
The most tolerogenic protocol will then be used to test prophylactic and therapeutic potential and also the immunological mechanism underlying this effect. (fapesp.br)
The effect of solnatide was observed using both prophylactic and therapeutic strategies and following local (intra-articular) and systemic (intravenous) administration. (apeptico.com)

Mice with collagen-induced arthritis (CIA) were treated with HAMCs after disease onset, and clinical scores and joint levels of mediators of inflammation were evaluated. (unicatt.it)
Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats. (nih.gov)
The goal of this study was to investigate whether the peripheral treatment with the sEH enzyme inhibitor 1- trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU) could prevent the hypernociception and inflammation in the albumin-induced arthritis model in rats' temporomandibular joint (TMJ). (nih.gov)
Genetic variants of PPAR-gamma coactivator 1B augment NLRP3-mediated inflammation in gouty arthritis. (cdc.gov)
Thus, the study is aimed at investigating the acute effect of a noninvasive transcutaneous vagus nerve stimulation on clinical disease activity and systemic levels of inflammation in patients with psoriatic arthritis or ankylosing spondylitis. (hindawi.com)
Psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are chronic autoimmune diseases characterized by peripheral and spinal joint inflammation. (hindawi.com)
Writing in Experimental and Therapeutic Medicine , researchers report that mice with collagen-induced arthritis who received an extract from Fructus sophorae (FSE)-the dried ripe fruit of S. japonicum -saw improvements to several factors related to inflammation and bone damage. (nutritionaloutlook.com)
Mice with more TTP in their bodies were resistant to the inflammation that accompanied these experimental models of disease," Blackshear said. (nih.gov)
CONCLUSION: The therapeutic effects of imiquimod on joint inflammation and bone destruction are dependent on TLR-7 sensing by PDCs and type I IFN signaling. (cnrs.fr)
Nanjundaiah, S.M., Astry, B. and Moudgil, K.D. (2013) Mediators of inflammation-induced bone damage in arthritis and their control by herbal products. (scirp.org)
They found in an experimental model of uveitis that levels of two factors that contribute to inflammation, TNFα and NF&kappaB, were reduced with melatonin treatment. (melatonina.it)
Pain, stiffness, and inflammation are the most common symptoms of arthritis. (healingblendsglobal.com)
In an antigen-induced arthritis model, solnatide peptide reduced cell influx and release of pro-inflammatory mediators into the joints, associated with reduction in oedema and tissue damage, as compared to controls indicating that the TNF-derived lectin-like solnatide peptide has anti-inflammatory effects in an acute model of joint inflammation, APEPTICO Forschung und Entwicklung GmbH today announced. (apeptico.com)

Researchers found a Fructus-sophorae extract protected against development of collagen-induced arthritis in mice. (nutritionaloutlook.com)
Following the onset of collagen-induced arthritis (CIA), the mice were randomized into one of three groups: a CIA control group, a group receiving 70 mg/kg of FSE once daily, and a group receiving 350 mg/kg of FSE once daily. (nutritionaloutlook.com)
Although mAbs against IL-19 and IL-20 have each been shown to modulate disease severity of collagen-induced arthritis in animal models, and anti-IL-20 therapeutic Ab has exhibited some efficacy in the treatment of RA in clinical trials, benefits for a complete blockade of these functionally redundant cytokines remain to be explored. (aai.org)
METHODS: Mice with K/BxN serum-induced arthritis, collagen-induced arthritis, and human tumor necrosis factor transgene insertion were studied. (cnrs.fr)
Mice with collagen-induced arthritis (CIA) were treated with anti-TNFα alone, anti-IL17 alone or a combination of the two. (ox.ac.uk)

Endogenous binding inhibitors in adjuvant arthritis may contribute to the observed decreased in diflunisal protein binding. (nih.gov)
By understanding the mechanisms, we may be able to develop better inhibitors to prevent disease and identify therapeutic targets for new treatment strategies,' says Holoshitz. (domain-b.com)
Paw swelling, plasma fibrinogen levels and urinary NO 2 - /NO 3 - excretion were measured to assess the effect of the inhibitors on the arthritis response and whole body NO biosynthesis. (elsevierpure.com)
In addition, NOS inhibitors may be only weakly therapeutic, or even detrimental, in established disease. (elsevierpure.com)
These findings should be considered when evaluating NOS inhibitors as potential therapeutic agents for the treatment of established human arthritis. (elsevierpure.com)
Experimental animal models of autoimmune disease and clinical studies that focused on IL-17 pathway inhibitors were included. (ru.nl)

Effect of experimental diabetes on elimination kinetics of diflunisal in rats. (nih.gov)
Celastrus was fed to LEW rats by gavage daily, beginning either before Mtb challenge (preventive regimen) or after the onset of AA (therapeutic regimen). (biomedcentral.com)
All rats were graded regularly for the signs of arthritis. (biomedcentral.com)
Arthritis was induced in male Lewis rats by the injection of adjuvant into the base of the tail. (elsevierpure.com)
In this study, we investigated the clinical efficacy of two lactobacillus and two bifidobacterium probiotic strains in experimental autoimmune myasthenia gravis (EAMG) and experimental autoimmune encephalomyelitis (EAE) models, induced in Lewis rats. (oncotarget.com)

HAMCs also protected the mice from experimental sepsis, inflammatory bowel disease, and autoimmune encephalomyelitis. (unicatt.it)
A study in mice showed reduced age-related disc degeneration using an experimental drug combination targeting aging cells. (nih.gov)
The study included 20 six-week-old BALB/c mice who were injected with bovine type-II collagen to induce arthritis. (nutritionaloutlook.com)
RESULTS: PDC-deficient mice showed exacerbation of inflammatory and arthritis symptoms after arthritogenic serum transfer. (cnrs.fr)
Middle cerebral artery occlusion (MCAO), experimental autoimmune encephalomyelitis (EAE) and LPS-induced sepsis mice models were constructed to investigate the therapeutic and anti-inflammasome effects of LND. (biomedcentral.com)
The data published on 31st October 2022 in Frontiers in Immunology ( https://doi.org/10.3389/fimmu.2022.1049368 ) for the first time demonstrate that solnatide significantly reduces inflammatory cell infiltration and joint damage in an immune-mediated experimental arthritis model in mice. (apeptico.com)

17. Topical imiquimod has therapeutic and immunomodulatory effects against intracranial tumors. (nih.gov)
Mesenchymal stem cells (MSC) present remarkable immunomodulatory ability, and these cells are potential therapeutic agents for autoimmune disorders. (biomedcentral.com)

Both plants (at dose 200 mg/kg body weight) significantly suppressed (but with different degrees) the incidence and severity of arthritis by increasing/decreasing the production of anti-inflammatory/pro-inflammatory cytokines, respectively, and activating the anti-oxidant defence system. (nih.gov)
After the induction of experimental arthritis, animals were assessed for nociceptive behavior test, leukocyte infiltration counts and histologic analysis, ELISA to quantify several cytokines and Western blotting. (nih.gov)
Glucosamine, an amino sugar, plays a role in improving arthritis in patients due to the anti-inflammatory action of glucosamine compounds that are associated with the suppression of neutrophil functions and proinflammatory cytokines ( 9 - 11 ). (spandidos-publications.com)

Diflunisal: a review of its pharmacological properties and therapeutic use in pain and musculoskeletal strains and sprains and pain in osteoarthritis. (nih.gov)
We suggest not offering therapeutic ultrasound for people with knee and/or hip osteoarthritis (OA). (racgp.org.au)

Our findings indicate that local recruitment and activation of PDCs represents an attractive therapeutic opportunity for RA patients. (cnrs.fr)
RESULTS: Preclinical studies suggest that IL-17A is an attractive therapeutic target. (ru.nl)

Here, we compared the anti-inflammatory/anti-oxidant activity of these two plants in rat adjuvant-induced arthritis (AIA). (nih.gov)

This technology has been used to compare existing models of individual neurons, as well as new models of neurons in peripheral tissues of the body, that reproduce previously published laboratory experimental results using computational methods. (nih.gov)
We provide advice on experimental design, choice of appropriate technologies and analytical methods, perform data quality control and analysis, and create user-friendly reports and publication-ready data visualizations. (hss.edu)

Dioxin also has been shown to increase severity in an experimental model of another autoimmune disease, multiple sclerosis. (domain-b.com)
Here, we find that LND strongly attenuates the inflammatory injury in experimental models of inflammasome-associated diseases including autoimmune disease-multiple sclerosis (MS), ischemic stroke and sepsis. (biomedcentral.com)

Compensatory anabolic signaling in the sarcopenia of experimental chronic arthritis. (jpccr.eu)

Here we will discuss the specificity of various NF-κB proteins, their role in inflammatory disease, the regulation of NF-κB activity by IκB proteins and IκB kinase (IKK), and the development of therapeutic strategies aimed at inhibition of NF-κB. (jci.org)

Imiquimod-dependent therapeutic effects were monitored by transcriptome analysis (using quantitative reverse transcriptase-polymerase chain reaction) and flow cytometric analysis of the periarticular tissue. (cnrs.fr)
In contrast, enhancing PDC recruitment and activation to arthritic joints by topical application of the Toll-like receptor 7 (TLR-7) agonist imiquimod significantly ameliorated arthritis in various mouse models. (cnrs.fr)

Therapeutic antibody targeting of CD97 in experimental arthritis: the role of antigen expression, shedding, and internalization on the pharmacokinetics of anti-CD97 monoclonal antibody 1B2. (southernbiotech.com)
[ 8 ] The same principles apply to monoclonal and polyclonal therapeutic antibodies. (medscape.com)

Animal models of RA have contributed significantly both to our understanding of the pathogenesis of autoimmune arthritis as well as to the testing of new therapeutic agents of natural or synthetic origin [ 18 - 21 ]. (biomedcentral.com)
Pathogenesis of haemophilic synovitis: experimental studies on blood-induced joint damage. (medscape.org)

Finally, we discuss some major advances to translate the experimental models on ex vivo and in vivo expanded and/or differentiated stem cells into clinical applications for the development of novel cellular therapies aimed at repairing genetically altered or damaged tissues/organs in humans. (nih.gov)
The design and clinical implementation of therapeutic antibodies are principally based on the biological functions of IgG molecules that confer protection against infectious diseases. (medscape.com)

For this purpose, we will use a BALB/c experimental model of arthritis induced by immunization with proteoglycan (PG). (fapesp.br)

The Genomics Center uses transcriptomics, epigenomics, and single-cell genomics to study disease genes and pathways, and is developing novel precision medicine therapeutic strategies for musculoskeletal conditions. (hss.edu)

The aim of this study was to characterize the effect of HAMCs on antigen-specific T cell responses in RA patients and to evaluate their therapeutic potential in a preclinical experimental model of RA. (unicatt.it)
A particular emphasis is made on the therapeutic potential of different tissue-resident adult stem cell types and their in vivo modulation for treating and curing specific pathological disorders. (nih.gov)
The therapeutic potential of cannabinoids such as THC is grossly limited by their psychoactive effects, leading to a growing interest in the development of synthetic analogs with similar benefits but without activity on the brain. (g11.co.in)
The aim of the present study was to elucidate preventive and therapeutic potential of stem cells for AD. (bdsh.co.kr)
Therefore, the aim of this study was to investigate the preventive and therapeutic potential of human adipose-derived stem cells (hASC) for PD and was to identify the related factors to this therapeutic effect. (bdsh.co.kr)
β2-Adrenoceptor-Mediated Upregulation of IL-17 May Contribute to Pulmonary Immunopathology in COVID-19: Does Blockade of IL-17 and β-Adrenergic Effects Hold a Therapeutic Potential? (brainimmune.com)

Disease activity accounts for long-term efficacy of IL-1 blockers in pyogenic sterile arthritis pyoderma gangrenosum and severe acne syndrome. (cdc.gov)
Arthritis is not one disease. (arthritis.org)
These results can serve as a guide to avoid side effects of epilepsy treatment and increase the therapeutic effects of bioelectronic medicine in the treatment of this disease. (nih.gov)
The treatment of Parkinson's disease (PD) using stem cells has long been the focus of many researchers, but the ideal therapeutic strategy has not yet been developed. (bdsh.co.kr)
Arthritis is a common disease among adults and the number one cause of disability. (healingblendsglobal.com)
In fact, the Center for Disease Control and Prevention estimates that in the US alone, there are around 54 million people diagnosed with arthritis and the number is expected to increase to 78 million by the year 2040. (healingblendsglobal.com)

Moreover, structural modifications to glucosamine by introducing new functional groups can be expected to improve its therapeutic effects ( 12 ). (spandidos-publications.com)
Improving the effects of human adipose tissue-derived mesenchymal stem cells (ASCs) on the demyelination and neurobehavioral function was investigated in an experimental model of neonatal hypoxic-ischemic encephalopathy (HIE). (bdsh.co.kr)
There is moderate-quality evidence that therapeutic ultrasound has statistically significant effects on pain and physical function in people with knee OA. (racgp.org.au)

Researchers have developed a promising approach to deliver therapeutic genes and gene editing tools to muscle more efficiently, thus requiring lower doses. (nih.gov)
Your genes play a significant role in the development of arthritis. (healingblendsglobal.com)

Degeneration of the cartilage leads to painful movement within the joints and this becomes arthritis. (healingblendsglobal.com)

TIP peptide, AP301) has also been shown to protect kidneys and to exert potent anti-inflammatory activity in an experimental glomerulonephritis model. (apeptico.com)

Pre-existing conditions like arthritis or bone cancer induce stress onto the bones, leading to a greater risk of BME within patients suffering from those conditions. (wikipedia.org)
Twenty patients with psoriatic arthritis (PsA) and 20 patients with ankylosing spondylitis (AS) were included and stimulated bilaterally with a handheld vagal nerve stimulator for 120 seconds 3 times a day for 5 consecutive days. (hindawi.com)
This open-label study provides support for an anti-inflammatory effect of transcutaneous vagus nerve stimulation in patients with psoriatic arthritis and ankylosing spondylitis. (hindawi.com)
Arthritis community connects patients with others online and in-person for support and education, and encourages patients to play an active role in their health care. (arthritis.org)
The Arthritis Foundation is mobilizing patients and their families to engage in studies comparing the effectiveness of treatments for juvenile arthritis and funding research for more options. (arthritis.org)
Therapeutic drug monitoring is recommended for all patients ( 2.5 , 5.17 ). (nih.gov)
CONCLUSIONS: These findings, which need to be confirmed in a larger cohort, suggest that a Th17-targeted therapeutic approach may be useful for anti-TNFα non-responder patients or as an adjunct to anti-TNFα therapy, provided that safety concerns can be addressed. (ox.ac.uk)

Furthermore, researchers have to consider that any, even very limited, mental stress or pain could compromise the experimental results and quality of scientific findings and, therefore, have consequently to be eliminated [ 10 ]. (biomedcentral.com)

The anti-arthritic activity of turmeric exceeded that of ginger and indomethacin (a non-steroidal anti-inflammatory drug), especially when the treatment started from the day of arthritis induction. (nih.gov)

Stem cells: a revolution in therapeutics-recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies. (nih.gov)
Here, we illustrate the biology of Ab-based therapeutics and highlight new technologies that could reinvigorate drug discovery for a number of brain diseases for which current therapeutic options are limited. (medscape.com)
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. (medecinesciences.org)

New study results out of Korea suggest an extract from the Japanese pagoda tree ( Styphnolobium japonicum L.) may help in mediating the symptoms of arthritis. (nutritionaloutlook.com)

AG had neither a prophylactic nor a therapeutic antiarthritic effect. (elsevierpure.com)
Therapeutic Effect of Melatonin in Experimental Uveitis," appears in the December issue of The American Journal of Pathology. (melatonina.it)
Finally combined blockade of TNFα and IL-17 in CIA was more effective than monotherapy, particularly with respect to the duration of the therapeutic effect. (ox.ac.uk)

As in the case of glucosamine, curcumin, extracted from C. longa , is a promising anti-inflammatory agent under various experimental conditions ( 13 , 14 ). (spandidos-publications.com)

Growing evidence suggests that targeting apoptosis-associated speck-like protein containing a CARD (ASC), the oligomerization of which is the key event for the assembly of inflammasome, may be another promising therapeutic strategy. (biomedcentral.com)

Technologies that improve bioavailability of antibody-based treatment platforms within the CNS parenchyma are being developed and could invigorate drug discovery for a number of brain diseases for which current therapeutic options are limited. (medscape.com)
Therapeutic ultrasound is the application of high-frequency sound waves to soft tissues via a treatment head moved over the surface of the skin. (racgp.org.au)

Arthritis and rheumatism. (medecinesciences.org)
Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. (medecinesciences.org)

Anatomy49

Organisms12

Diseases51

Chemicals and Drugs81

Analytical, Diagnostic and Therapeutic Techniques and Equipment45

Psychiatry and Psychology2

Phenomena and Processes19

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena4

Humanities1

Information Science2

Health Care24

Rheumatoid arthritis61

Prophylactic and therapeutic3

Inflammation13

Collagen-induced5

Inhibitors6

Rats5

Mice6

Immunomodulatory2

Cytokines3

Osteoarthritis2

Attractive therapeutic2

Adjuvant-induced arthritis1

METHODS2

Multiple sclerosis2

Chronic1

Inhibition1

Imiquimod2

Monoclonal2

Pathogenesis2

Clinical2

BALB1

Musculoskeletal1

Potential6

Disease6

Effects3

Genes2

Degeneration1

Model1

Patients7

Researchers1

Induction1

Biology3

Symptoms of arthritis1

Effect3

Anti-inflammatory1

Inflammasome1

Treatment2

Rheumatism2