ScintigraphySPECTInfarctionIschemiaCardiacRadiopharmaceuticalsSestamibiUptakeViabilityIsotopeNuclear MedicineCardiology studiesPlanarArtifactsComputed tomographyRadionuclide ImagingViableEvaluateStressPhysiologicTracerPeakCoronary arteriesMethodsPatientsScansClinicalConventionalBoneScientistsFunctionTechniquesWall motion
Scintigraphy7
- Technetium pyrophosphate scintigraphy indicated marked diffuse myocardial uptake of technetium pyrophosphate, strongly suggesting transthyretin cardiac amyloidosis, which was firmly confirmed by a left ventricular endomyocardial biopsy. (biomedcentral.com)
- Technetium pyrophosphate scintigraphy was extremely useful for definitive diagnosis. (biomedcentral.com)
- Given the high quality of FDG-PET imaging, the likelihood that other useful PET tracers will be approved for clinical applications, and the enthusiasm with which the larger radiology community has embraced PET/CT, the future of single-photon scintigraphy in diagnostic imaging is a relevant discussion for nuclear medicine and radiology departments. (diagnosticimaging.com)
- Although fluorine-18 FDG can be used to identify infectious foci, it is less specific than In-111 white blood cell (WBC) scintigraphy, which can also be used in a dual-tracer study if it is necessary to compare bone marrow distribution with Tc-99m sulfa colloid and the In-111 WBC images. (diagnosticimaging.com)
- Even skeletal scintigraphy is likely to continue to be performed with Tc-99m tracers (rather than F-18) for at least the next five years. (diagnosticimaging.com)
- In addition, the same images can be fused with the tomographic scintigraphy (SPECT) images, producing SPECT/CT images. (hygeia.gr)
- Tomographic myocardial scintigraphy with new Τc-99m labeled radiopharmaceuticals (SESTAMIBI, ΤETROFOSMIN) and simultaneous multi-gated myocardial contractility (Quantitative Gated SPECT). (hygeia.gr)
SPECT10
- With multihead SPECT systems, imaging can often be completed in less than 10 minutes. (wikipedia.org)
- Cardiac SPECT Imaging guides you through all aspects of the modality--from basic principles (acquiring and processing images, quality control). (chipsbooks.com)
- Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) with technetium-99m ( 99m Tc)-labelled radiotracers. (cadth.ca)
- Background: The aim of this study was to test a relational database including clinical data and imaging findings in a large cohort of subjects with suspected or known Coronary Artery Disease (CAD) undergoing stress single-photon emission computed tomography (SPECT) myocardial perfusion imaging. (cnr.it)
- Imaging findings suggest that the use of SPECT imaging in our laboratory is appropriate. (cnr.it)
- SPECT, which uses a rotating camera system and tomographic reconstruction to produce a 3-dimensional image, is more common in the United States. (msdmanuals.com)
- It is injected at peak stress and imaged with SPECT, followed 4 hours later by injection of half the original dose during rest and by repeat SPECT. (msdmanuals.com)
- The decreased number of requests to our department for Ga-67 imaging has been compensated for by the growth in utilization of other planar and SPECT imaging. (diagnosticimaging.com)
- With the recent extension of reimbursement to include FDG-PET imaging of the brain for limited applications, I expect that the use of SPECT for assessment of cerebral imaging will decline, but this procedure accounted for only a few studies per week. (diagnosticimaging.com)
- The SPECT radiopharmaceutical segment is further sub-segmented into Technetium-99m, Thallium-201, Iodine-123, and others. (medgadget.com)
Infarction11
- It can also detect regions of myocardial infarction by showing areas of decreased resting perfusion. (wikipedia.org)
- Similarly, if tissue damage (heart attack, myocardial infarction, cardiac stunning or hibernation) is to be determined, this is done under "resting" conditions. (wikipedia.org)
- and clinical applications (evaluating myocardial infarction and coronary artery disease). (chipsbooks.com)
- Nuclear cardiology studies are used to assess myocardial blood flow, evaluate the heart's pumping function, and visualize the size and location of a myocardial infarction. (medscape.com)
- After acute myocardial infarction, myocardial perfusion imaging can help estimate prognosis because it can show extent of the perfusion abnormality due to acute myocardial infarction, extent of scarring due to previous infarcts, and residual peri-infarct or other areas of reversible ischemia. (msdmanuals.com)
- Patients with persistent ST segment elevation or acute Q wave myocardial infarction, and those with alternative diagnoses, exit from this guideline and should be managed appropriately. (bmj.com)
- Patients with unstable angina or non-Q wave myocardial infarction should have their cardiac prognosis assessed by estimation of their risk of death or further cardiac events. (bmj.com)
- Those patients with unstable angina or non-Q wave myocardial infarction whose condition has stabilised, but who are at high risk of death or further cardiac events , should be referred for coronary angiography. (bmj.com)
- [6] Such a strategy may determine long-term risk and future therapy but cannot address the risk of acute perioperative myocardial infarction, which has a high mortality rate. (silverchair.com)
- A man in his seventies presented with a history of cerebral infarction with occlusion of the left middle cerebral artery, diabetes mellitus, renal dysfunction, as well as prior myocardial infarction and arteriosclerosis obliterans. (journalmc.org)
- He also had diabetes mellitus and renal dysfunction, as well as a prior history of myocardial infarction and arteriosclerosis obliterans. (journalmc.org)
Ischemia7
- The diagnostic information is generated by provoking controlled regional ischemia in the heart with variable perfusion. (wikipedia.org)
- Preoperative non-invasive testing aims to provide information primarily about coronary artery disease (myocardial ischemia or reduced blood supply to the heart muscle), left ventricular (LV) dysfunction, and heart valve abnormalities in selected patients. (cadth.ca)
- Myocardial ischemia is a disorder that is usually caused by a critical coronary artery obstruction, which is also known as atherosclerotic coronary artery disease (CAD). (medscape.com)
- Diagnosing myocardial ischemia prior to a heart attack is important. (medscape.com)
- ii) Discomfort or pain due to myocardial ischemia, with or without necrosis of heart muscle. (socialsecurityprofessionals.com)
- In patients with severe coronary artery disease with low ischemic threshold, as in the present case, acetazolamide might reduce peripheral vascular resistance, increase the cardiac output ratio, increase myocardial oxygen consumption by increasing cardiac output, and induce myocardial ischemia with elevation of double product. (journalmc.org)
- Although the frequency of acute heart failure due to myocardial ischemia after an acetazolamide challenge may be low, its occurrence in patients with severe arteriosclerotic disease should be routinely considered. (journalmc.org)
Cardiac6
- As with nuclear imaging for other cardiac indications, the relative distribution of the radionuclide allows for visualization of blood flow through the heart and gives information regarding the functional capacity of the heart. (cadth.ca)
- 7,8 Through sequential image acquisition, the gamma camera works with a computer to evaluate cardiac function and perfusion. (cadth.ca)
- In patients with ischemic heart disease who undergo revascularization based on PET viability assessment with fludeoxyglucose F-18 (F-18 FDG), those with a low myocardial perfusion reserve were at an increased risk of adverse cardiac events. (medscape.com)
- Thus, we propose that the nuclear imaging technique should be taken into account even for an exploratory diagnosis of transthyretin cardiac amyloidosis. (biomedcentral.com)
- Stress Testing In stress testing, the heart is monitored by electrocardiography (ECG) and often imaging studies during an induced episode of increased cardiac demand so that ischemic areas potentially at risk. (msdmanuals.com)
- iii) Syncope, or near syncope, due to inadequate cerebral perfusion from any cardiac cause, such as obstruction of flow or disturbance in rhythm or conduction resulting in inadequate cardiac output. (socialsecurityprofessionals.com)
Radiopharmaceuticals2
- The assessment of myocardial perfusion and function using PET and hybrid positron emission tomography (PET)/CT imaging is becoming more available as the cost of the technology decreases and as positron-emitting radiopharmaceuticals become more available. (medscape.com)
- Newer gamma cameras using simultaneous 180° acquisition appear to have the potential of offering similar benefits as PET technology but are able to use the less costly technetium (TC)-99m-based radiopharmaceuticals and thallium-201 (Tl-201). (medscape.com)
Sestamibi1
- By the late 1980s, two different compounds containing technetium-99m were introduced: teboroxime and sestamibi. (wikipedia.org)
Uptake1
- After stress testing, the perfusion imbalance between normal coronary arteries and those distal to a stenosis appears as a relative decrease in Tl-201 uptake in the areas perfused by the stenosed arteries. (msdmanuals.com)
Viability1
- With its unique ability to evaluate perfusion at the cellular level and to assess perfusion at peak exercise stress, MPI plays an important role in diagnosing cardiovascular disease, establishing prognosis, assessing the effectiveness of therapy, and evaluating viability. (snmjournals.org)
Isotope1
Nuclear Medicine3
- Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (myocardium). (wikipedia.org)
- In addition to guest-edited issues on all aspects of nuclear medicine, radionuclide therapy, molecular imaging, radiology and radiotherapy including basic research. (openmedscience.com)
- Open Medscience is a platform to discuss a range of medical imaging technologies, including proton therapy, radiosurgery, nuclear medicine and radiation therapy. (openmedscience.com)
Cardiology studies1
- and the majority of nuclear cardiology studies (technetium-99m MIBI/tetrafosmin and thallium-201). (diagnosticimaging.com)
Planar2
- and GI motility studies (gastric emptying, reflux) that typically involve planar imaging. (diagnosticimaging.com)
- Tomographic imaging reveals information from the depth of the examined organs that is not possible to be received by the conventional planar imaging. (hygeia.gr)
Artifacts1
- Whereas MPI is a valuable diagnostic tool, it is also a complex physiologic imaging process, which exposes it to several potential pitfalls and artifacts that can limit the utility of the study. (snmjournals.org)
Computed tomography1
- Radionuclide imaging can expose patients to similar amounts of radiation than do comparable computed tomography (CT) studies. (msdmanuals.com)
Radionuclide Imaging1
- Radionuclide imaging uses a special detector (gamma camera) to create an image following injection of radioactive material. (msdmanuals.com)
Viable1
- I actually had occasion to make this decision three years ago, and my conclusion was 'yes,' despite the fact that we have a viable PET imaging program and are delighted with the way it has augmented patient diagnosis and management. (diagnosticimaging.com)
Evaluate3
- The goal of this protocol is to evaluate reversible perfusion defects that may warrant intervention. (msdmanuals.com)
- Most of the F-18 FDG-PET imaging in our department is done in patients with tumor to evaluate extent of disease and response to therapy, as well as to monitor for recurrence. (diagnosticimaging.com)
- Appropriate medically acceptable imaging means that the technique used is the proper one to evaluate and diagnose the impairment and is commonly recognized as accurate for assessing the cited finding. (socialsecurityprofessionals.com)
Stress6
- In keeping with the concept of comparison images, the second "stress" image was taken 4 hours after "stress" and compared with the first. (wikipedia.org)
- 1 The basic principle of radionuclide MPI is to administer a radiopharmaceutical intravenously and image blood flow to the heart muscle (myocardial perfusion), both at rest and under stress. (cadth.ca)
- however, in patients with a moderate-to-high risk for CAD, an imaging study is essential along with the stress test. (medscape.com)
- Visual comparison of stress and delayed images can be supplemented by quantitative displays. (msdmanuals.com)
- Radioactive thallium-201 (Tl-201), which acts as a potassium analog, was the original tracer used in stress testing. (msdmanuals.com)
- Der udføres sædvanligvis en optagelse i hvile og en under arbejdsbelastning (ergometercykling) eller farmakologisk stress. (ugeskriftet.dk)
Physiologic1
- One potentially important physiologic parameter obtained by these newer technologies is the myocardial perfusion reserve (MPR). (medscape.com)
Tracer1
- It has also had a negative impact on the use of other single-photon tracer-labeled tumor diagnostic imaging agents, such as CEA-Scan (Immunomedics) for staging colorectal carcinoma and NeoTect (Berlex) for differential diagnosis of solitary pulmonary nodules. (diagnosticimaging.com)
Peak1
- Individuals could be placed on a treadmill and be "stressed" by the "Bruce protocol" and when near peak performance, could be injected with thallium-201. (wikipedia.org)
Coronary arteries1
- The normal anatomy of the coronary arteries is shown in the image below. (medscape.com)
Methods1
- Methods: We developed a relational database including clinical and imaging data of 7995 subjects with suspected or known CAD. (cnr.it)
Patients4
- Myocardial perfusion imaging in very elderly patients with suspected coronary artery disease: never too late! (cnr.it)
- Myocardial perfusion imaging (MPI) is an important imaging modality in the management of patients with cardiovascular disease. (snmjournals.org)
- Myocardial perfusion imaging (MPI) is a valuable tool in the management of patients with cardiovascular disease. (snmjournals.org)
- Bright View XCT achieves superior image quality and reduces the data acquisition time in half, reducing the overall examination duration on patients' benefit. (hygeia.gr)
Scans1
- Currently, nuclear myocardial scans include both perfusion and gated wall motion images. (medscape.com)
Clinical2
- It is not reasonable, however, to make decisions based on anticipation of clinical needs beyond a single instrument's life-cycle, such as five to 10 years, as there are too many variables that could affect the practice of diagnostic imaging beyond that time. (diagnosticimaging.com)
- Both agents were just being introduced when FDG imaging became available to clinical departments, initially with dual-detector coincident imaging, and, for the past three years, with dedicated ring detector imaging systems. (diagnosticimaging.com)
Conventional1
- a) Bright View γ-camera, with 2 heads of variable angle, which is able to acquire anterior and posterior or bilateral images simultaneously, reducing by half the examination time in comparison to the conventional single head γ-camera. (hygeia.gr)
Bone1
- The bone scan segment is further sub-segmented into Technetium-99m 1st, fluoride-18 2nd, and others. (medgadget.com)
Scientists1
- By the mid-1970s, scientists and clinicians alike began using thallium-201 as the radioisotope of choice for human studies. (wikipedia.org)
Function1
- The movement of Tl-201 reflected differences in tissue delivery (blood flow) and function (mitochondrial activity). (wikipedia.org)
Techniques1
- Among the techniques of nuclear cardiology, myocardial perfusion imaging is the most widely used. (medscape.com)
Wall motion1
- Den regionale systoliske pumpefunktion kan vurderes ud fra wall-motion (myokardievæggens bevægelser bedømt ud fra endokardiets bevægelser) og wall-thickening (fortykkelse af myokardievæggen i systolen, hvilket ses som en øgning af myokardiets intensitet). (ugeskriftet.dk)