• Treatment with anti-IL-12/23p40 or anti-IL-23p19 Abs greatly inhibited 12- O -tetradecanoylphorbol-13-acetate-induced epidermal hyperplasia in the ears of K5.Stat3C mice, whereas the inhibitory effect of an anti-IL-17A Ab was relatively less prominent. (jimmunol.org)
  • In addition, we demonstrated that the E2 repression could be antagonized by phorbol 12-myristate 13-acetate, which stimulated c-Jun phosphorylation on serine 63, a process that is a prerequisite for recruitment of the transcriptional coactivator cAMP response element binding protein (CREB)-binding protein (CBP). (hku.hk)
  • The painting of mouse dorsal skin with 1 2-0-tetradecanoylphorbol-l3-acetate (TPA) (0.2-2.5 nrTiol/mouse) induced a dose-related increase in vascular permeability, which was determined by pontamine sky blue exudation mto the skin 5 hr after the TPA treatment. (elsevier.com)
  • Els factors de transcripció de la família Snail són fonamentals en la "transició epiteli-mesènquima", procés morfogènic essencial en el desenvolupament embrionari i en els fenòmens metastàsics tumorals. (tesisenred.net)