• Now, through a long-term study involving thousands of women and children, researchers have found that elevated maternal blood glucose levels even below those meeting traditional GDM diagnostic criteria increase the risk of future type 2 diabetes in mothers and impaired glucose metabolism and greater excess fat in children ages 10 to 14 years post-delivery. (nih.gov)
  • Chromium has been shown to be useful in its ability to support insulin thereby assisting in healthy glucose metabolism. (herbalmagic.ca)
  • Eating fatty fish decreased the lipophilic index in people with impaired glucose metabolism or coronary heart disease, according to a new study from the University of Eastern Finland. (news-medical.net)
  • Researchers summarized the inter-relationship between diet, glucose metabolism, and sleep. (news-medical.net)
  • Calcium metabolism modifiers such as bisphosphonates are stable analogues of inorganic pyrophosphate. (medscape.com)
  • The effect of deletion of these combinations on cellular metabolism has been studied by flux balance analysis. (nih.gov)
  • In the journal Angewandte Chemie , a research team has now described how a very low dose of a rhenium metal complex interferes with cellular metabolism to such an extent that it kills ovarian cancer cells. (phys.org)
  • Older dibenzazepines with a carboxamide substitution have been demonstrated to cause deleterious effects on lipid metabolism profile, as well as frequent hyponatremia. (redheracles.net)
  • The aim of our study is to assess the effects of eslicarbazepine acetate, a novel AED, on lipid metabolism profile, sodium values and liver function tests, as well as to compare them with previous effects of carbamazepine and oxcarbazepine. (redheracles.net)
  • Early studies that compared germ-free mice and conventionally raised mice suggested that the gut microbiota may play a role in host lipid metabolism. (news-medical.net)
  • Given that there is a link between lipid levels and obesity, it is possible that the effect of certain bacterial taxa on host lipid metabolism is the same species that affect the host's weight. (news-medical.net)
  • The objective was to investigate whether the consumption of isoflavone-enriched foods for 1 y affects bone mineral density, bone metabolism, and hormonal status in early postmenopausal women. (nih.gov)
  • Bone Metabolism and Select Exercise Classes" by Tori M. Stone, Jonathan E. Wingo et al. (wku.edu)
  • The purpose of this study was to assess the efficacy of structured physical activity classes on bone metabolism. (wku.edu)
  • My lab is focused on understanding the pathogenic interplay between oncogenic mutations, chronic inflammation and aberrant metabolism as a driver of the evolutionary processes that culminate in lethal myeloid malignancies. (lls.org)
  • The primary goal of our research proposal is to better understand the interplay between inflammation and metabolism, and to develop strategies for clinical trials aimed at preventing AML development. (lls.org)
  • The discovery of a form of low-grade systemic and chronic inflammation ("metaflammation"), linked to inducers (broadly termed "anthropogens") associated with modern man-made environments and lifestyles, suggests an underlying basis for chronic disease that could provide a 21st-century equivalent of the germ theory. (cdc.gov)
  • This form of classical inflammation is typically a short-term response to infection and injury, aimed at removing the infective stimulus and allowing repair of the damaged tissue, ultimately resulting in healing and a return to homeostasis. (cdc.gov)
  • From the beginning, researchers have tweaked and altered the parameters of the urban metabolism model. (wikipedia.org)
  • C. Kennedy and fellow researchers have produced a clear definition in the 2007 paper The Changing Metabolism of Cities claiming that urban metabolism is "the sum total of the technical and socio-economic process that occur in cities, resulting in growth, production of energy and elimination of waste. (wikipedia.org)
  • Correlation and mediation analysis revealed one potential mechanism that Cef may first change the intestinal microbiota (such as destroying its normal structure, reducing its abundance and the stability of the microbial network or certain microbe abundance like Alistipes), and then change the intestinal metabolism (such as acetate , caproate, propionate ), leading to liver metabolic disorder (such as spermidine , inosine , cinnamaldehyde). (bvsalud.org)
  • Here, we report the identification of efficient metabolism disruption strategies by analysis of a reactome network. (nih.gov)
  • The considerable overlap between atRA-associated processes and the immunological defects seen in progressive HIV-1 infection forms the basis of this study, with a primary aim to determine whether disruption of vitamin A metabolism in gut mucosae contributes to HIV-1 disease progression and persistence. (harvard.edu)
  • ETFL is a hierarchical model formulation, from metabolism to RNA synthesis, that allows simulating thermodynamics-compliant intracellular fluxes as well as enzyme and mRNA concentration levels. (nature.com)
  • These compounds are involved in nucleic acid metabolism, methyl transfer, and myelin synthesis and repair. (msdmanuals.com)
  • However, that is not denying the tremendous progress DMPK scientists have made in understanding absorption, distribution, metabolism and excretion (ADME) processes, contributing to enhanced drug design and the avoidance of DDIs, especially when set against a background of rising commercial, societal, regulatory and budgetary pressures. (europeanpharmaceuticalreview.com)
  • Li, Zhengze, "Microbiota-mediated metabolism of curcumin in the gastrointestinal tract and its implications in anti-colitis" (2021). (umass.edu)
  • A new Science study sheds light on how the gut microbiota interacts with circadian rhythm to impact metabolism. (neurosciencenews.com)
  • Since the gut microbiota is clearly linked to the human host, does this mean that host metabolism is affected by the gut microbiota? (news-medical.net)
  • Graduate student Valentina Botero is first author on a study of how NF1 mutations disrupt metabolism in fruit flies. (scripps.edu)
  • With the growing concern of climate change and atmospheric degradation, the use of the urban metabolism model has become a key element in determining and maintaining levels of sustainability and health in cities around the world. (wikipedia.org)
  • Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy and will not occur by themselves, by coupling them to spontaneous reactions that release energy. (wikipedia.org)
  • In four years, it has made the scientific case for developing drugs that target enzymes involved in cancer cell metabolism. (acs.org)
  • Metabolic modeling, which helps making sense of the metabolism in a biological network, is an important tool for engineering biocatalysts, with applications in biofuels, drug design, microbial community analysis, and personalized medicine. (nature.com)
  • Metabolism is the internal biological process that determines how quickly your body turns calories into energy. (blogarama.com)
  • Calories are not shunted into storage in fat tissue, but rather used-oxidized, in biological terms-by the rest of the body and the brain. (harvard.edu)
  • GEMs are particularly amenable to flux balance analysis (FBA), which models metabolism at the fluxome level using linear optimization techniques. (nature.com)
  • We recommend using our Formula S/B metabolism booster if you are or will be consuming more sugar than usual, such as desserts, wine, and carbohydrates, or if you experience hunger and energy crashes throughout the day from blood sugar spikes following carbohydrate-rich meals. (herbalmagic.ca)
  • The objective of this study was to evaluate whether long-term shift work is associated with both the total hormonal secretion after awakening and the pattern of the cortisol levels during the first hour following awakening, among 65 randomly selected police officers who represent a high stress occupation. (cdc.gov)
  • They found there was no change in metabolism after six weeks between those who ate nothing for breakfast and those who consumed 700 calories before 11am - 350 of these within two hours of waking. (dailymail.co.uk)
  • A faster metabolism means that your body burns calories more efficiently, even when you're at rest. (timesofisrael.com)
  • Cutting back on calories, the time-honored approach to weight loss, will work for the short term. (harvard.edu)
  • Drug Metabolism and Pharmacokinetics (DMPK) is a scientific discipline once primarily associated with safety evaluation in drug development that has, in the last two decades, become a core discipline within drug discovery, development and even post-marketing. (europeanpharmaceuticalreview.com)
  • Regarding boosting your metabolism and achieving your weight loss goals, PhenQ stands out as the best metabolism booster supplement on the market. (timesofisrael.com)
  • Essentially, whether you're on a Herbal Magic Weight Loss Plan or not, if you're going to be indulging in sugars over the weekend, on vacation, during a holiday or have been enjoying more sugar than normal then this is the metabolism booster you need! (herbalmagic.ca)
  • The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, each step being facilitated by a specific enzyme. (wikipedia.org)
  • A striking feature of metabolism is the similarity of the basic metabolic pathways among vastly different species. (wikipedia.org)
  • These effects on lipoprotein metabolism may be exerted through specific modulation of the expression of the LDL receptor and apolipoprotein B genes. (cambridge.org)
  • Long-term effects on liver metabolism induced by ceftriaxone sodium pretreatment. (bvsalud.org)
  • Lastly, the correlations and mediation analysis between the liver metabolism and gut metabolism /microbes were carried, and the potential mechanisms of the mal-effects on gut- liver axis induced by Cef pretreatment were accordingly discussed. (bvsalud.org)
  • Therefore, it is plausible that it can also have other effects on host metabolism. (news-medical.net)
  • An inherited metabolic disorder that involves mitochondrial metabolism dysfunction. (yeastgenome.org)
  • In recent years, studies of neurofibromatosis type 1 in people and in animal models have begun turning up evidence that the disorder also involves abnormalities in metabolism. (scripps.edu)
  • According to dictionary.com, metabolism is the sum of the (physical and chemical) processes in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. (tdan.com)
  • Metabolism (/məˈtæbəlɪzəm/, from Greek: μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms. (wikipedia.org)
  • The word metabolism can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transportation of substances into and between different cells, in which case the above described set of reactions within the cells is called intermediary (or intermediate) metabolism. (wikipedia.org)
  • However, the predictive capability of allometry is limited for low clearance compounds, a requirement for oral drug candidates, as it does not account for species differences in metabolism. (europeanpharmaceuticalreview.com)
  • Urban metabolism is a model to facilitate the description and analysis of the flows of the materials and energy within cities, such as undertaken in a material flow analysis of a city. (wikipedia.org)
  • Later, in reaction against industrialization and coal use, Sir Patrick Geddes, a Scottish biologist, undertook an ecological critique of urbanization in 1885, making him the first scientist to attempt an empirical description of societal metabolism on a macroeconomic scale. (wikipedia.org)
  • GDM is known to confer short- and long-term health risks to mothers and children. (nih.gov)
  • The findings pointed out gaps in knowledge about how best to treat women diagnosed with the alternative criteria, and the absence of evidence about long-term outcomes and benefits for these women with or without treatment-as well as the potential for short-term harms, such as the additional stress a woman can experience when diagnosed with GDM. (nih.gov)
  • My long-term goal is to improve patient outcomes by establishing therapies that prevent and/or delay evolution to acute leukemia. (lls.org)
  • It's a recipe for long-term weight control without restriction or deprivation. (harvard.edu)
  • Associations of long-term shift work with waking salivary cortisol concentration and patterns among police officers. (cdc.gov)
  • The results show that long-term midnight shift work is associated with decreased absolute mean level and total volume of cortisol released over the waking period. (cdc.gov)
  • Another aim was to study the long-term effect of thyroxine replacement on the plasma concentrations of coagulation factors and to ascertain the duration of thyroxine treatment needed to restore haemostatic function. (lu.se)
  • Our results demonstrated that in the GI tract curcumin underwent phase I metabolism to yield three metabolites and two broken down products, namely tetrahydro-curcumin (THC), hexahydro-curcumin (HHC), octahydro-curcumin (OHC), ferulic acid (FA), and dihydroferulic acid (DFA). (umass.edu)
  • Curcumin, phase I metabolites, FA, and DFA then were subject to phase II metabolism to yield their corresponding conjugated phase II metabolites. (umass.edu)
  • Systems biology has long been interested in models capturing both metabolism and expression in a cell. (nature.com)
  • The metabolism of cancer cells is also different from the metabolism of normal cells, and these differences can be used to find targets for therapeutic intervention in cancer. (wikipedia.org)
  • An obvious outcome of this study is a rational identification of drug targets, to efficiently bring down mycobacterial metabolism. (nih.gov)
  • A study team led by MedUni Vienna's Center for Brain Research has charted how cell types that form neuroendocrine command centers that control virtually all aspects of bodily metabolism evolve during brain development. (medicalxpress.com)
  • Aside from being a great advocate and populariser for urban metabolism, Girardet significantly coined and drew the difference between a 'circular' and 'linear' metabolism. (wikipedia.org)
  • Metabolism Research Centre for screening genital hypothyroidism is high in our re- after discharge from hospitals on the 3rd-7th gion. (who.int)
  • Cobalamin is a general term for compounds with biologic vitamin B12 activity. (msdmanuals.com)
  • which was often surprisingly small, in material terms, compared with its overall material inputs. (wikipedia.org)
  • The nine weight-loss principles -- and the 200 tips that help you incorporate them into your lifestyle -- in Fire Up Your Metabolism are surprisingly simple: Eat breakfast before you get to work. (simonandschuster.com)
  • Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress. (wikipedia.org)
  • They also used metabolism to describe the material and energy exchange between nature and society in as a critique of industrialization (1883) which created an interdependent set of societal needs brought into play through the concrete organization of human labour. (wikipedia.org)
  • Your metabolism is the process by which your body converts food into energy. (timesofisrael.com)
  • eating in the morning helps keep your body at its metabolism-boosting best. (popsugar.com)
  • These natural and effective methods have been carefully selected to provide practical solutions to rev up and boost your metabolism, and shed unwanted pounds for healthy body weight again. (timesofisrael.com)
  • a low metabolism means your body burns fat. (blogarama.com)
  • They told me that I had put my body into "starvation mode" and that my metabolism was slowed to a snail's pace. (tdan.com)
  • Enter search terms to find related medical topics, multimedia and more. (msdmanuals.com)
  • Our findings suggest that we should look at the neuronal regulation of metabolism in people to better understand this disease, and potentially find more effective ways to treat it," Tomchik says. (scripps.edu)