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CatalaseHydrogen PeroxideSuperoxide DismutaseAmitroleAcatalasiaGlutathione PeroxidaseOxidative StressAntioxidantsPeroxidasesReactive Oxygen SpeciesTerm BirthLipid PeroxidationMicrobodiesOxidation-ReductionOxidantsFree RadicalsGlutathioneGlutathione ReductaseFree Radical ScavengersSuperoxidesMalondialdehydeOxygenXanthine OxidaseLiverThiobarbituric Acid Reactive SubstancesPeroxidesGlucose OxidaseHydroxyl RadicalParaquatHemeMolecular Sequence DataOrganoidsHydroxidesPeroxidaseOxidoreductasesKineticsTime FactorsPeroxisomesAscorbate PeroxidasesAerobiosisErythrocytesAscorbic Acid

Superoxide DismutaseAscorbate peroxidaseOxidative stressCell lysatesAssayMitochondrialActivityDecreasesLiverOrganismsHydrogenMammalianDeficiencyInactivated with aminoRecombinantCorneaProteinMeSHExposureSensitivityCold TemperatureSubunitsGenusCellsResultsExamineBacterial0.05OxygenEffectsSearchLong termOccurMaximumShort termMajorWater

Superoxide Dismutase7

• Corneal glutathione (GSH) and malondialdehyde (MDA) levels, as well as the activities of superoxide dismutase (SOD), catalase, glutathione peroxidase (GSH-Px), and glutathione reductase (GSH-Rd) in cornea were measured to monitor corneal injury. (molvis.org)
• Sirtuin 1 attenuates oxidative stress via upregulation of superoxide dismutase 2 and catalase in astrocytes. (uchicago.edu)
• SBL-1 treatment (12 mg/kg body weight) 30 min before irradiation (i) countered brain injuries, (ii) reduced CTA (38.7 ± 3.0%, day 1) and (iii) normalized brain DA, NE, E, superoxide dismutase, catalase and CTA from day 3 onwards. (greenmedinfo.com)
• Molecular docking analysis for different enzymes involved in aging (collagenase, elastase and hyaluronidase), antioxidant enzymes (superoxide dismutase, glutathione-s-transferase, glutathione peroxidase and catalase) and mitochondrial enzymes (nicotinamide adenine dinucleotide (NAD)+hydrogen (H) dehydrogenase, succinate dehydrogenase, cytochrome c oxidase and adenosine triphosphate synthase) was carried out for epigallocatechin gallate alone (1), withaferin A alone (2), epigallocatechin gallate and withaferin A in combination (3) and a reference molecule. (ijpsonline.com)
• Under cold stress, D. versiformis inoculation did not change the activity of superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD) in leaves and roots, whereas P. indica inoculation significantly increased the activity of CAT in roots and POD in leaves only. (techscience.com)
• Endogenous antioxidant enzyme activity in the liver, i.e., catalase and superoxide dismutase activity, was not adversely affected. (sun.ac.za)
• Consequently, this pilot placebo-controlled study was designed to evaluate the effect of long-term (12 weeks) oral administration of single low-dose (300mg) of the nonsteroidal anti-inflammatory drug, aspirin on the antioxidant enzymes (catalase, glutathione peroxides (GPx), and superoxide dismutase (SOD)) activities and the intracellular levels of reduced glutathione (GSH) and lipid peroxidation of PBCM in patients with vitiligo in the active phase. (e-ijd.org)

Ascorbate peroxidase1

• Moreover, the application of the investigated 75 μM MJ significantly improved enzyme activities in terms of catalase, peroxidase and ascorbate peroxidase activities. (springer.com)

Oxidative stress3

• Catalase is an enzyme found in nearly all living organisms and is used as a defense against oxidative stress, specifically by degrading the hydrogen peroxide (H 2 O 2 ) into water and oxygen. (kennesaw.edu)
• To examine the effect of catalase gene transfer on survival of corneal endothelial cells (EC) following challenge with hydrogen peroxide (H 2 O 2 ) in an ex vivo model of oxidative stress. (bmj.com)
• The supplementation of Trans-resveratrol attenuated the cardiac oxidative stress and increased the activity of catalase. (bvsalud.org)

Cell lysates1

• We have demonstrated successful penetration of catalase into the BHK mammalian cells using cell penetrating peptide (CPP) technology: both fluorescence from catalase conjugated with amino dye 555, and catalase activity in cell lysates, is significantly higher in CPP+catalase treated cells than in cells treated with catalase alone. (kennesaw.edu)

Assay2

• Chance B, Maehly A (1995) Assay of catalase and peroxidase. (springer.com)
• catalase functional activity in lysates was determined using a H 2 O 2 activity assay. (bmj.com)

Mitochondrial1

• Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage. (uchicago.edu)

Activity11

• The maximal activity of catalase was observed between pH 6.0 and 8.0. (tubitak.gov.tr)
• Enzyme activity was stable at temperatures between 10 and 30°C. The activity of purified catalase was inhibited by azide, cyanide, \beta -mercaptoethanol, dithiotreitol (DTT) and iodoacetamide. (tubitak.gov.tr)
• In untreated rats exposed to C-H-R, there was a significant increase in malondialdehyde (MDA) levels in liver and muscle along with decreased activity of catalase (CAT) and glutathione-S-transferase (GST) in liver and muscle. (nih.gov)
• Have direct antimicrobial activity, necessary for oxidative cross-reaction and can act as signals induce HR. Their induction following pathogen attack is termed the oxidative burst . (bspp.org.uk)
• The application of ascorbic acid reduced cell membrane damage and increased catalase activity in water-stressed trees of both cultivars. (frontiersin.org)
• Increased catalase activity was observed in brassinolide treated plants followed by salicylic acid and ascorbic acid under salinity. (arccjournals.com)
• In this study, coelomocytes of L. variegatus and A. punctulata were exposed to UVB (302 nm) for one or two hours, and catalase activity was measured using colorimetric assays. (bellarmine.edu)
• 0.05) were observed among the groups in relation to plasma catalase activity, depending on exposure time, no significant differences were found in terms of glutathione and malondialdehyde levels. (twoday.net)
• A rare autosomal recessive disorder resulting from the absence of CATALASE activity. (nih.gov)
• Make fresh for each lesson, because catalase activity reduces noticeably over 2/3 hours. (practicalbiology.org)
• The lipid peroxidation (TBARS) and the enzymatic activity of catalase (CAT) were measured in the cardiac muscle. (bvsalud.org)

Decreases3

• Similarly, significant increase in Lipid Peroxidation (LPO) level while induced significant decreases in the activities of liver Catalase (CAT) and Glutathione-S-Transferase (GST). (scialert.net)
• 0.05) decreases were determined among the groups in terms of reproductive organ weights (uterus and ovaries) and progesterone and estrogen levels in relation to the varying periods of the estrous cycle. (twoday.net)
• It is concluded that exposure to the ELF-EMFs for different time periods produced significant decreases in plasma catalase activities in the 3-month exposure groups but no effects on progesterone level, on 17-beta estradiol level, or on the morphology and weight of uterus and ovaries. (twoday.net)

Liver4

• Although widely distributed among animals, plants, bacteria, and fungi, catalase in mammalian liver and blood has been most intensively studied. (drugfuture.com)
• Catalase for commercial use obtained from animal liver, bacterial ( Micrococcus lysodeikticus), and fungal (Aspergillus niger) sources. (drugfuture.com)
• The antioxidant status was disturbed with the decrease in SOD, GST and catalase in the liver and membrane-ATPases as well. (nature.com)
• In liver, the diet KEECC significantly increased catalase expression compared with diet 0. (stir.ac.uk)

Organisms4

• To prevent this cellular damage, organisms generate enzymes, such as catalase, that breakdown ROS into harmless substances. (bellarmine.edu)
• Elevated catalase activities under UVB, a range of UVR from 280-315 nm, exposure have been detected for many aquatic organisms. (bellarmine.edu)
• Although the effects of herbicides are relatively well known in terms of environmental impacts on non-target organisms, there is very little scientific evidence regarding the impacts of herbicide residues on aquatic arthropods from tropical conservation areas. (bvsalud.org)
• The hallmark of disease are infections with catalase-positive organisms, especially deep-seated abscesses, osteomyelitis, and chronic granulomata. (lu.se)

Hydrogen2

• Cells make the enzyme catalase to remove hydrogen peroxide. (practicalbiology.org)
• This investigation looks at the rate of oxygen production by the catalase in pureed potato as the concentration of hydrogen peroxide varies. (practicalbiology.org)

Mammalian2

• First, does the catalase traffic to peroxisomes, its correct location in mammalian cells? (kennesaw.edu)
• Secondly, does catalase delivered as cargo on a cell penetrating peptide protect mammalian cells against damage from H 2 O 2 ? (kennesaw.edu)

Deficiency1

• These results are in agreement with our earlier findings on erythrocytes of a subject with a genetic deficiency of catalase. (nih.gov)

Inactivated with amino1

• The catalase within normal, intact human erythrocytes was completely inactivated with amino triazole. (nih.gov)

Recombinant2

• A recombinant adenovirus vector (AdCL) was used to transfer human catalase cDNA into EC of whole thickness rabbit corneas ex vivo. (bmj.com)
• Recombinant Helicobacter pylori catalase. (wjgnet.com)

Cornea1

• UVB irradiation caused significant damage to the corneas, including apparent corneal ulcer and severe epithelial exfoliation, leading to decrease in the activities of SOD, catalase, GSH-Px, GSH-Rd, and GSH content in cornea, whereas there was increased corneal MDA content as compared with the control group. (molvis.org)

Protein1

• Protein S-glutathionylation provided a method for assessing physiological effects of CPP delivered catalase. (kennesaw.edu)

MeSH1

• Catalase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)

Exposure1

• These data are discussed in terms of three exposure periods-acute (14 days or less), intermediate (15-364 days), and chronic (365 days or more). (cdc.gov)

Sensitivity1

• A total of 87 isolates of Mycobacterium tuberculosis were collected from patients in all regions of Lebanon and characterized in terms of drug sensitivity. (who.int)

Cold Temperature1

• Such short-term treatment of cold temperature did not cause any significant change in root fungal colonization and spore density in soil. (techscience.com)

Subunits2

• SDS-gel electrophoresis results indicated that chicken erythrocyte catalase consists of four apparently identical subunits, with a molecular weight of around 57.5 kDa. (tubitak.gov.tr)
• All catalases so far isolated contain four tetrahedrally arranged subunits of equal size giving an approximate mol wt of 240,000. (drugfuture.com)

Genus1

• The name Hafniaceae is derived from the Latin term Hafnia, referring the type genus of the family and the suffix "-aceae", an ending used to denote a family. (wikipedia.org)

Cells3

• This rate was determined in control cells and in catalase-inactivated cells while the cells were exposed to H2O2, which was generated at various constant and predetermined rates by glucose oxidase. (nih.gov)
• Confocal microscopy was used to quantify the colocalization of TaT-CaM delivered catalase to the peroxisome, the known subcellular location of catalase, in baby hamster kidney (BHK) cells. (kennesaw.edu)
• Preliminary densitometry analysis shows a statistically significant difference between the S-glutathionylation in CPP catalase treated cells and the non treated cells. (kennesaw.edu)

Results4

• The results indicated that catalase handles approximately half of the generated H2O2. (nih.gov)
• Our results show that treatment of chamomile plants with 75 µM MJ leads to increases in plant growth in terms of flower, straw and root dry weights. (springer.com)
• Here, we present results from colocalization and physiological protection of CPP delivered catalase assayed to date. (kennesaw.edu)
• The results were analyzed in terms of binding energy and different interacting residues. (ijpsonline.com)

Examine1

• To examine the morphological effects of catalase gene transfer in modulation of H 2 O 2 induced injury, transduced corneas were maintained in ex vivo culture and challenged with H 2 O 2 . (bmj.com)

Bacterial1

• Bacterial isolates were subjected to microscopic examination using Gram's staining technique and biochemical tests (e.g. coagulase, catalase, oxidase, and motility). (who.int)

0.051

• 0.05) ameliorate corneal damage and increase the activities of SOD, catalase, GSH-Px, GSH-Rd, and GSH content, and decrease the MDA content in corneas when compared with the UVB-treated group. (molvis.org)

Oxygen1

• Catalase plays a major role in the protection of tissues from the toxic effects of H_{2}O_{2} and partially reduced oxygen species. (tubitak.gov.tr)

Effects2

• Symposium of Student Scholars: Does CPP delivered catalase have measurable physiological effects? (kennesaw.edu)
• This information can help minimize the risk of long-term reproductive effects in non-target species that have been previously overlooked in ecotoxicology studies. (bvsalud.org)

Search1

• Advanced Search queries use a traditional Term Search. (osti.gov)

Long term5

• Store at -20°C long term. (abcam.com)
• Water availability for irrigation is among the most critical factors that affect fruit tree growth in commercial orchards and tree production in nurseries, especially considering the long-term and costly investments of planting fruit tree orchards. (frontiersin.org)
• Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia. (uchicago.edu)
• Sub-objective 3.3: Investigation of genome evolution of L. monocytogenes exposed to long-term nutrient-limiting, non-selective stress condition. (usda.gov)
• Long-term antibiotic therapy (co-trimoxazole, itraconazole). (lu.se)

Occur1

• However, an unexpected result with the present approach was the finding that the increased dependence on the glutathione peroxidase/reductase mechanism did not occur until greater than 98% of the catalase had been inactivated. (nih.gov)

Maximum1

• Following incubation with AdCL, catalase expression reached maximum at 5-7 days. (bmj.com)

Short term2

• Shipped at 4°C. Store at +4°C short term (1-2 weeks). (abcam.com)
• Experimental work started with short term single driver experiments but soon developed to include multiple drivers and sometimes even successive generations in an attempt to address as much of climate change's complexity as possible and include adaptive, trans-generational aspects to project physiological reaction norms into the future. (easychair.org)

Major1

• This graph shows the total number of publications written about "Catalase" by people in this website by year, and whether "Catalase" was a major or minor topic of these publications. (uchicago.edu)

Water1

• In general terms, different response mechanisms to cope with water stress in presence of ascorbic acid were found in each cultivar, with 'Scarletprince' trees preferentially using proline as compatible solute and 'CaroTiger' trees relying on stomatal regulation. (frontiersin.org)