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ChorioamnionitisFood TechnologyMeatFetal Membranes, Premature RuptureAmniotic FluidPregnancyObstetric Labor, PrematureAmnionUnited States Department of AgricultureExtraembryonic MembranesChorionUreaplasma InfectionsSuperficial Back MusclesPremature BirthCookingGestational AgeFood HandlingPlacentaInfant, PrematureObserver VariationPregnancy Complications, InfectiousReproducibility of ResultsInfant, NewbornTrimethylsilyl CompoundsCattleUreaplasmaBronchopulmonary DysplasiaConsumer SatisfactionFood PackagingLabor, ObstetricTasteLeukemoid ReactionAbortion, SepticAdrenergic beta-3 Receptor AgonistsMastodyniaMuscle, SkeletalTerm BirthSheep, DomesticInfant, Premature, DiseasesMeat-Packing IndustryHistocompatibility, Maternal-FetalSheepTime FactorsFetusUmbilical CordTrenbolone AcetateRespiratory Distress Syndrome, NewbornAmniocentesisCalpainAbruptio PlacentaeRetrospective StudiesEndometritisFood InspectionFetal DistressFetal DeathProspective StudiesCalcium ChloridePalpationDelivery, ObstetricBreedingFood-Processing IndustryFood PreservationRandom AllocationFood QualityTreatment OutcomeBetamethasoneLenses, IntraocularMeconiumFetal Organ MaturityVacuumPlacenta DiseasesInterleukin-1alphaChemokine CXCL10Chemokine CXCL11Ureaplasma urealyticumBody CompositionSepsisMedroxyprogesterone AcetateTomography, X-Ray ComputedMatrix Metalloproteinase 8

FluidFetal tachycardia MaternalUterine tendernessDiagnosisPrelabor Rupture oObstetricChorionResults from an infectionNeonatalSubclinicalHistologicMeconiumMembranesVaginalFetusAbscessBacterialClinicalMaternal feverPreterm deliveryIntrapartumDeliveriesAcuteComplicationsDisordersSexuallyRiskInflammationInfectiousTreatmentAdministrationLaborEvidence

Fluid8

• At term mothers who experience a combination of pre-labor membrane ruptures and multiple invasive vaginal examinations, prolonged labor, or have meconium appear in the amniotic fluid are at higher risk than at term mothers experiencing just one of those events. (wikipedia.org)
• It is in direct contact with the amniotic fluid, which surrounds the fetus. (wikipedia.org)
• The amniotic fluid exists within the amnion, and is where the fetus is able to grow and develop. (wikipedia.org)
• The swelling of the amnion and chorion is characteristic of chorioamnionitis, occurring when bacteria makes its way into the amniotic fluid and creates an infection within the amniotic fluid. (wikipedia.org)
• Diagnosis is by specific clinical criteria or, for subclinical infection, analysis of amniotic fluid. (msdmanuals.com)
• Some medical professionals regard maternal intrapartum fever as synonymous with chorioamnionitis, an infection of the tissue and amniotic fluid surrounding a baby in the womb. (rossfellercasey.com)
• Diagnosis is by ultrasonographic measurement of amniotic fluid volume. (merckmanuals.com)
• If peritonitis is present, amniotic fluid contamination is a special concern. (reanfoundation.org)

Fetal tachycardia Maternal1

• Additional risk factors include: Fetal tachycardia Maternal leukocytosis (>15,000 cells/mm³) Purulent cervical drainage Diagnosis is typically not confirmed until after delivery. (wikipedia.org)

Uterine tenderness1

• The signs and symptoms of clinical chorioamnionitis include fever, leukocytosis (>15,000 cells/mm³), maternal (>100 bpm) or fetal (>160 bpm) tachycardia, uterine tenderness and preterm rupture of membranes. (wikipedia.org)

Diagnosis5

• When intrapartum (during delivery) fever is higher than 39.0°C, suspected diagnosis of chorioamnionitis can be made. (wikipedia.org)
• Alternatively, if intrapartum fever is between 38.0°C and 39.0°C, an additional risk factor must be present to make a presumptive diagnosis of chorioamnionitis. (wikipedia.org)
• On the other hand, a wide variety of obstetrical pathologies can obscure, confuse, and delay the diagnosis of intra-abdominal injury. (medscape.com)
• Local penile factors and systemic diseases, including diabetes, cardiac disease, and neurologic disorders, can cause ED. Diagnosis is via physical exam and history. (lecturio.com)
• Before making a definitive diagnosis, consider the many obstetric conditions that pose greater fetal risk (eg, chorioamnionitis, abruptio placentae). (reanfoundation.org)

Prelabor Rupture o1

• 3 Study Design: It was a single-blinded randomized clinical trial including pregnant women at 24-36 +6 weeks with viable singleton pregnancies and confirmed preterm prelabor rupture of membranes who attended the Aswan University Hospital from January 01, 2020, to June 01, 2021. (researchsquare.com)

Obstetric2

• Causes of chorioamnionitis stem from bacterial infection as well as obstetric and other related factors. (wikipedia.org)
• Infection increases risk of obstetric complications and problems in the fetus and neonate. (msdmanuals.com)

Chorion3

• Chorioamnionitis, also known as intra-amniotic infection (IAI), is inflammation of the fetal membranes (amnion and chorion), usually due to bacterial infection. (wikipedia.org)
• The amniotic sac consists of two parts: The outer membrane is the chorion. (wikipedia.org)
• The chorion is the last and outermost of the membranes that make up the amniotic sac. (wikipedia.org)

Results from an infection2

• Chorioamnionitis results from an infection caused by bacteria ascending from the vagina into the uterus and is associated with premature or prolonged labor. (wikipedia.org)
• Intraamniotic infection typically results from an infection that ascends through the genital tract. (msdmanuals.com)

Neonatal1

• Ampicillin 2 gm IV every 6 hrs for 2 days) and azithromycin (Azithromycin 1000 mg PO once) is effective to prolong latency period, decrease incidence of chorioamnionitis and improve neonatal outcomes in women with PPROM between 24 - 36+6 weeks. (researchsquare.com)

Subclinical2

• Confirmed histologic chorioamnionitis without any clinical symptoms is termed subclinical chorioamnionitis and is more common than symptomatic clinical chorioamnionitis. (wikipedia.org)
• However, infection may not cause typical symptoms (ie, subclinical infection). (msdmanuals.com)

Histologic1

• Chorioamnionitis is diagnosed from a histologic (tissue) examination of the fetal membranes. (wikipedia.org)

Meconium1

• Complications include perinatal asphyxia, meconium aspiration, polycythemia. (merckmanuals.com)

Membranes1

• Premature deliveries, ruptures of the amniotic sac membranes, prolonged labor, and primigravida childbirth are associated with this condition. (wikipedia.org)

Vaginal3

• The risk of developing chorioamnionitis increases with number of vaginal examinations performed in the final month of pregnancy, including labor. (wikipedia.org)
• Chorioamnionitis is caught early by looking at signs and symptoms such as fever, abdominal pain, or abnormal vaginal excretion. (wikipedia.org)
• Manifestations may include uterine pain and tenderness and vaginal bleeding, possibly with hemorrhagic shock and disseminated intravascular coagulation. (merckmanuals.com)

Fetus2

• Severe chorioamnionitis may be accompanied by vasculitis of the umbilical blood vessels due to the fetus' inflammatory cells. (wikipedia.org)
• Chickenpox exposure in pregnancy can pose risks to both the mother and fetus, including fetal varicella syndrome. (passmed.uk)

Abscess1

• More severe chorioamnionitis involves subamniotic tissue and may have fetal membrane necrosis and/or abscess formation. (wikipedia.org)

Bacterial3

• Bacterial, viral, and even fungal infections can cause chorioamnionitis. (wikipedia.org)
• Birthing-related events, lifestyle, and ethnic background have been linked to an increase in the risk of developing chorioamnionitis apart from bacterial causation. (wikipedia.org)
• This category will also be used in primary coding to classify bacterial infections of unspecified nature or site. (cdc.gov)

Clinical2

• Intraamniotic infection is suspected and diagnosed based on clinical and sometimes laboratory criteria. (msdmanuals.com)
• Prostaglandin synthetase inhibitors (eg, indomethacin) are used cautiously for tocolysis because they mask the clinical signs of infection or cause maternal platelet dysfunction. (reanfoundation.org)

Maternal fever3

• The presence of fever between 38.0°C and 39.0°C alone is insufficient to indicate chorioamnionitis and is termed isolated maternal fever. (wikipedia.org)
• It's also known as intrapartum maternal fever, maternal intra-partum fever, and pyrexia in labor. (rossfellercasey.com)
• A sudden spike in maternal fever during labor that includes the administration of an epidural may result in serious risks to the baby in an otherwise low-risk delivery. (rossfellercasey.com)

Preterm delivery2

• Intraamniotic infection can cause as well as result from preterm PROM or preterm delivery. (msdmanuals.com)
• @laina Four factors in maternal trauma or surgery predict fetal morbidity and mortality-hypoxia, infection, drug effects, and preterm delivery. (reanfoundation.org)

Intrapartum2

• Committee Opinion No. 712: Intrapartum management of intraamniotic infection. (msdmanuals.com)
• Maternal intrapartum fever can lead to numerous complications for mother and baby, including both infectious and noninfectious conditions. (rossfellercasey.com)

Deliveries1

• This infection accounts for 50% of deliveries before 30 weeks gestation. (msdmanuals.com)

Acute1

• CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)

Complications1

• are also potential complications but are uncommon if infection is treated. (msdmanuals.com)

Disorders1

• Hypertensive disorders of pregnancy include chronic hypertension, gestational hypertension, preeclampsia/eclampsia, and hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome. (lecturio.com)

Sexually2

• Sexually transmitted infections, chlamydia and gonorrhea, can cause development of the condition as well. (wikipedia.org)
• Gonorrhea is a sexually transmitted infection (STI) caused by the gram-negative bacteria Neisseria gonorrhoeae (N. gonorrhoeae). (lecturio.com)

Risk1

• Tobacco and alcohol use also puts mothers at risk for chorioamnionitis development. (wikipedia.org)

Inflammation1

• The term triple I refers to intrauterine infection or inflammation or both and is defined by strict diagnostic criteria, but this terminology has not been commonly adopted although the criteria are used. (wikipedia.org)

Infectious1

• certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)

Treatment3

• Treatment includes broad-spectrum antibiotics, antipyretics, and delivery. (msdmanuals.com)
• Treatment includes conservative management with lifestyle modifications, oral medications, and injectables. (lecturio.com)
• however, the intrauterine environment may not be ideal, and the treatment of preterm labor may exacerbate the effects of intra-abdominal disease. (reanfoundation.org)

Administration1

• Administration of antibiotics if the amniotic sac bursts prematurely can prevent chorioamnionitis occurrence. (wikipedia.org)

Labor1

• Broad-spectrum antibiotics are usually administered when an infection is pre-existing or identified during labor. (rossfellercasey.com)

Evidence2

• Oral antibiotics are not necessary as there is no evidence of secondary infection. (passmed.uk)
• Discussion: Serological evidence of previous HBV, HCV and HIV infection was not significantly different between BD and control groups. (acamedicine.org)