Loading...
  • variants
  • In situ hybridization studies of developing chicken bones, using a cDNA probe that hybridizes to all chicken tenascin splice variants, showed specific labelling of both osteogenic and chondrogenic regions of developing endochondral bones. (biologists.org)
  • deficiency
  • Tenascin-X deficiency is associated with Ehlers-Danlos syndrome. (thefreedictionary.com)
  • In 2001, a new autosomal recessive type of EDS caused by deficiency of tenascin-X was identified, which is characterized by joint hypermobility, skin hyperextensibility, and easy bruising. (asahq.org)
  • We describe postintubation tracheal rupture in a patient with tenascin-X deficiency. (asahq.org)
  • cartilage
  • RESULTS: Increased intensity of tenascin-C staining was observed in the damaged cartilage compared with normal cartilage. (jrheum.org)
  • Activated RelA staining in chondrocyte nuclei was prominent in tenascin-C-positive areas of OA cartilage. (jrheum.org)
  • Immunofluorescence
  • METHODS: Human articular cartilages were obtained from patients with OA and immunofluorescence examination of tenascin-C and the activated RelA subunit was performed. (jrheum.org)
  • subunit
  • Chicken osteoblast cultures synthesized almost exclusively the largest tenascin subunit, whereas fibroblast cultures from periostea of chicken calvariae synthesized approximately equal amounts of all three subunits. (biologists.org)
  • Collagen
  • We show that in a three-dimensional collagen type I matrix, the presence of tenascin-C, commonly elevated in high-grade gliomas, increased the invasiveness of glioma cells. (aacrjournals.org)
  • bone
  • Chiovaro F, Martina E, Bottos A, Scherberich A, Hynes NE, Chiquet-Ehrismann R. Transcriptional regulation of tenascin-W by TGF-beta signaling in the bone metastatic niche of breast cancer cells. (springer.com)
  • Kimura H, Akiyama H, Nakamura T, de Crombrugghe B. Tenascin-W inhibits proliferation and differentiation of preosteoblasts during endochondral bone formation. (springer.com)
  • cell proliferation
  • Cai J, Lu W, Du S, Guo Z, Wang H, Wei W, Shen X. Tenascin-C Modulates Cell Cycle Progression to Enhance Tumour Cell Proliferation through AKT/FOXO1 Signalling in Pancreatic Cancer. (jcancer.org)
  • complications
  • 5,6 However, the complications related to anesthesiologic procedures in tenascin-X-deficient type EDS have not been reported in the literature. (asahq.org)
  • human
  • Tenascin was secreted into the medium and deposited in the matrix by human and rat osteoblast-like cell lines, as well as by primary osteoblast-enriched cultures from chick embryo calvarial bones. (biologists.org)