• Given the importance of mRNA as an information-carrying molecule, the machinery that regulates mRNA levels and destroys faulty mRNA is critical in ensuring that errors in the genetic code are not passed on to proteins. (bio-medicine.org)
  • Our in silico simulations using a two-letter alphabet show that template-directed ligation and high concatenation rates counter compositional bias and shift the pool toward longer sequences, permitting greater exploration of sequence space and stable folding. (nih.gov)
  • We verified experimentally that unbiased DNA sequences are more efficient templates for ligation, thus increasing the compositional diversity of the pool. (nih.gov)
  • In contrast, template-directed ligation skewed the distribution qualitatively toward longer lengths (Figure 2a and Supplementary Data), resulting in a substantial excess of long sequences compared to an exponential distribution. (nih.gov)
  • that selfish genetic elements were discovered almost a century ago and have since been found in virtually all species? (wikipedia.org)
  • A complete biotic flight system is fully integrated into your nervous system and often includes biotic parts custom-grown from stem cells with your genetic information, granting you a fly speed equal to your base speed with good maneuverability. (wikidot.com)
  • The second step detects lung nodules using deformable 3D and 2D templates describing typical geometry and gray-level distribution within the nodules of the same type. (hindawi.com)