This Skin Notation Profile provides the SK assignments and supportive data for pentachlorophenol (PCP). (cdc.gov)
Data1
Agency (EPA) (IRIS 2010), and International Agency for Research on Cancer (IARC 2019) concluded that the data suggested an association between pentachlorophenol exposure and increased risk of non-Hodgkin lymphoma based on the consistent findings across epidemiological studies. (cdc.gov)
Document1
The Assessment Report is a technical document which contains information on threats to drinking water quality and quantity for municipal sources. (notreeaupotable.ca)
Found2
Impure pentachlorophenol (the form usually found at hazardous waste sites) is dark gray to brown and exists as dust, beads, or flakes. (cdc.gov)
We found positive associations of obesity with hexachlorobenzene (HCB), ß-hexachlorocyclohexane (ß-HCH) and chlorpyrifos, diabetes with pentachlorophenol (PCP), fipronil and fipronil sulfone, hypertension with PCB180 and chlorpyrifos, and dyslipidemia with diflufenican and oxadiazon, among others. (bvsalud.org)
Sale2
Health Canada's Pest Management Regulatory Agency (PMRA), under the authority of the Pest Control Products Act , is proposing registration for the sale and use of Pentachlorophenol Treated Poles and Cross-Arms, containing the technical grade active ingredient Pentachlorophenol, for use in new line construction and replacement of damaged utility poles and/or cross-arms used in the transmission and distribution of electricity. (canada.ca)
In August 2010, in response to the discovery of a potentially toxic metabolite in technical grade PCNB to be used in fungicide formulations, the sale of PCNB was halted by the U.S. EPA until the issue could be resolved. (wikipedia.org)
Group2
In the Health Effects Chapter there was frequent reference to a group of infants exposed because pentachlorophenol which was used as an anti-mildew agent. (cdc.gov)
The TUV Rheinland Group is a leading provider of technical services worldwide. (psma.com)
Report1
Bishop Museum Technical Report 35(5): 1-59. (yvonne-unden.de)
Wood2
Pentachlorophenol was widely used as a pesticide and wood preservative. (cdc.gov)
The grades are based on the percentage of clear, defect-free wood in the board. (blacklocustlumber.com)
Quality3
MARSHALLTOWN Brick Trowels are designed for durability and offers professional-grade quality to help you complete all functional or decorative brick, block, and stonework. (carbourtools.com)
With Premium Grade, each piece is individually inspected to ensure premium quality, durability and appearance. (blacklocustlumber.com)
With landscape grade, each individual piece of Black Locust is carefully inspected to ensure quality and durability. (blacklocustlumber.com)
Furans2
We performed a systematic review of published studies pertaining to cancer risk in relation to pentachlorophenol exposure, focusing on results pertaining specifically to all cancer sites and specific hematopoietic cancers, and data pertaining to risks associated with other types of chlorophenols, dioxins, or furans. (nih.gov)
Humoral immunotoxicity of polychlorinated diphenyl ethers, phenoxyphenols, dioxins and furans present as contaminants of technical grade pentachlorophenol. (nih.gov)
19842
Since 1984, the purchase and use of pentachlorophenol has been restricted to certified applicators. (cdc.gov)
Use by the general public was restricted in 1984, and pentachlorophenol application was limited to industrial areas (e.g., utility poles, railroad crossties, fence posts). (nih.gov)
Contaminants2
We reviewed currently available data to determine the extent to which recent studies assist in distinguishing the effect of pentachlorophenol from that of its contaminants (e.g., dioxins and other chlorophenols). (nih.gov)
Health Effects - Reduces specific health-related contaminants such as lead, pesticides and cysts which cause diarrhea, cramps, nausea and low grade fever as well as being potentially fatal. (watershop.my)
Wood preservative2
Pentachlorophenol was widely used as a pesticide and wood preservative. (cdc.gov)
Pentachlorophenol, a fungicide widely used as a wood preservative, was classified in 1999 by the International Agency for Research on Cancer as a possible human carcinogen. (nih.gov)
Exposure8
Agency (EPA) (IRIS 2010), and International Agency for Research on Cancer (IARC 2019) concluded that the data suggested an association between pentachlorophenol exposure and increased risk of non-Hodgkin lymphoma based on the consistent findings across epidemiological studies. (cdc.gov)
In the case of the infants exposed to pentachlorophenol, the exposure resulted from the misuse of an anti-mildew agent containing sodium pentachlorophenate. (cdc.gov)
The extension of a large cohort study of sawmill workers, with follow-up to 1995, provided information about risks of relatively rare cancers (e.g., non-Hodgkin lymphoma, multiple myeloma), using a validated exposure assessment procedure that distinguishes between exposures to pentachlorophenol and tetrachlorophenol. (nih.gov)
In contrast with dioxin, pentachlorophenol exposure has not been associated with total cancer incidence or mortality. (nih.gov)
The updated cohort study focusing on pentachlorophenol provides increased statistical power and precision, and demonstrates associations between hematopoietic cancer and pentachlorophenol exposure not observed in earlier evaluations of this cohort. (nih.gov)
Contaminant confounding is an unlikely explanation for the risks seen with pentachlorophenol exposure. (nih.gov)
raised concerns about the risk of non-Hodgkin lymphoma and soft-tissue sarcoma in relation to pentachlorophenol exposure. (nih.gov)
Under these exposure conditions, T-PCP produced a dose-related suppression of the antibody response whereas analytical grade PCP was without effect. (nih.gov)
Fungicide1
In August 2010, in response to the discovery of a potentially toxic metabolite in technical grade PCNB to be used in fungicide formulations, the sale of PCNB was halted by the U.S. EPA until the issue could be resolved. (wikipedia.org)
Conclusions1
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-349: Pentachlorophenol (87-86-5). (nih.gov)
Immunosuppressive2
Previous studies have demonstrated that the humoral immune response in mice as measured by the splenic IgM response to sheep erythrocytes (SRBC) is highly sensitive to suppression by technical grade (86%) pentachlorophenol (T-PCP) whereas analytical grade (greater than 99%) PCP is not immunosuppressive. (nih.gov)
It has been reported that technical grade PCP had immunosuppressive effects and that the immune system was the major target of PCDD/PCDFs toxicity. (tmu.edu.tw)
Cancer1
A number of epidemiological cohort and case-control studies have evaluated the potential associations between pentachlorophenol and cancer. (cdc.gov)
Feed Studies1
18. NTP Toxicology and Carcinogenesis Studies of Two Pentachlorophenol Technical-Grade Mixtures (CAS No. 87-86-5) in B6C3F1 Mice (Feed Studies). (nih.gov)
Effect1
Other studies examined the carcinogenic effect of pentachlorophenol in experimental animals. (nih.gov)
Associations2
The pentachlorophenol studies presented considerable evidence pertaining to hematopoietic cancers, with strong associations seen in multiple studies, in different locations, and using different designs. (nih.gov)
We found positive associations of obesity with hexachlorobenzene (HCB), ß-hexachlorocyclohexane (ß-HCH) and chlorpyrifos, diabetes with pentachlorophenol (PCP), fipronil and fipronil sulfone, hypertension with PCB180 and chlorpyrifos, and dyslipidemia with diflufenican and oxadiazon, among others. (bvsalud.org)
Results1
The goal of technical physics is to study energy transformations and its interactions with matter, and results in the most varied applications. (tecnopiemonte.com)
Test1
Genetic Toxicity Evaluation of Pentachlorophenol, Technical in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)
Date1
NSF is recognised around the world for its scientific and technical expertise in health and environmental sciences and, to date, offers its services in more than 155 countries. (watershop.my)