• Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of technetium Tc 99m tilmanocept injection in the elderly. (allinahealth.org)
  • Technetium-99m (99mTc) is a short-lived (half-life about 6 hours) metastable nuclear isomer used in nuclear medicine, produced from molybdenum-99. (wikipedia.org)
  • Isotopes of technetium Technetium (99mTc) sestamibi http://www-nds.iaea.org/sgnucdat/c3.htm Cumulative Fission Yields, IAEA K. Yoshihara, "Technetium in the Environment" in "Topics in Current Chemistry: Technetium and Rhenium", vol. 176, K. Yoshihara and T. Omori (eds. (wikipedia.org)
  • Technetium-99m (99mTc) is used in approximately 85% of diagnostic imaging procedures in nuclear medicine worldwide. (iaea.org)
  • 99mTc teboroxime, another promising new perfusion agent, is a boronic acid adduct of technetium dioxime complexes. (biomedsearch.com)
  • Technetium-99m-ECD had rapid washout from the inflamed tissue, while 99mTc-HMPAO had avid uptake. (nih.gov)
  • Technetium-99m (99mTc) and rhenium-188 (188Re) are two transition elements that share a similar chemistry. (lexology.com)
  • Technetium (99mTc) tetrofosmin is a drug used in nuclear medicine cardiac imaging. (morebooks.de)
  • Technetium (99mTc) arcitumomab is a drug used for the diagnostic imaging of colorectal cancers, marketed by Immunomedics. (morebooks.de)
  • Technetium (99mTc) arcitumomab is an immunoconjugate. (morebooks.de)
  • Before application, arcitumomab is reconstituted with a solution of the radioactive agent sodium pertechnetate (99mTc) from a technetium generator. (morebooks.de)
  • Technetium-99m sestamibi and 99mTc-tetrofosmin are at present the preferred tracers for simultaneous assessment of myocardial perfusion and function by gated single-photon emission tomography (SPET). (biomedsearch.com)
  • BACKGROUND: Increased pulmonary epithelial permeability evaluated by the rate of clearance from lung to blood of the radioaerosol solute technetium-99m labelled diethylenetriamine pentaacetate (99mTc-DTPA) has been reported in smokers and in workers exposed to silica dust. (bmj.com)
  • The ability of technetium 99m labelled polyclonal human immunoglobulin G (99mTc-IgG) scintigraphy and conventional bone scintigraphy with technetium 99m labelled hydroxymethylene diphosphonate (99mTc-HDP) to detect and to differentiate between the different degrees of arthritis activity was studied in 24 patients with rheumatoid arthritis (RA) and 10 patients with osteoarthritis (OA). (springer.com)
  • Technetium-99m (99mTc) is used for imaging and diagnostic purposes of organs and tissue. (statpearls.com)
  • This activity describes the indications, actions, and contraindications of technetium-99m (99mTc) as a valuable agent in imaging and diagnostics. (statpearls.com)
  • Describe the typical imaging findings associated with technetium-99m (99mTc) use. (statpearls.com)
  • Summarize the indications of technetium-99m (99mTc) use. (statpearls.com)
  • Review the adverse effects of technetium-99m (99mTc). (statpearls.com)
  • dimercaptosuccinic acid chelate labeled with technetium-99m (99mtc-dmsa) is the radiopharmaceutical of choice for high-resolution imaging of the renal cortex and estimation of the functional renal mass. the aim of this study was to evaluate a simplified method for determining the absolute renal uptake (aru) of 99mtc-dmsa prior to nephrectomy, using the radioactivity counts of nephrectomy specimens as the gold standard. (oalib.com)
  • Twelve dogs with idiopathic epilepsy underwent interictal technetium-99m-ethyl cysteinate dimer SPECT of the brain. (wiley.com)
  • Background: Recent technical developments using solid-state technology have enabled rapid image acquisition with single photon emission computed tomography (SPECT) and have led to a renewed interest in technetium-99m-teboroxime (Tc-99m-teboroxime) as a myocardial imaging agent. (harvard.edu)
  • With reference to the past and the probable future shortage of technetium-99m, it has been expected that there can be a shift from SPECT to PET or other alternate imaging modalities in the future. (transparencymarketresearch.com)
  • Technetium-99m is a medical radioisotope and used in gamma camera and SPECT for body imaging. (researchmoz.us)
  • Technetium-99m HMPAO SPECT brain scans were acquired on a multi-detector gammacamera and analysed visually and with statistical parametric mapping (SPM99). (bmj.com)
  • Conclusion: Technetium-99m-ECD has proven to be of value for interictal and ictal rCBF SPECT in childhood epilepsy. (elsevier.com)
  • A series of monocationic complexes of N-substituted-3-hydroxy-2-methyl-4-pyridinones labeled with technetium(IV)-99m have been evaluated in vivo as potential radiopharmaceuticals. (ubc.ca)
  • An electrophoretic procedure is outlined for the determination of the number of ligands bound to technetium-99m radiopharmaceuticals. (elsevier.com)
  • Marzilli, LG , Worley, P & Burns, HD 1979, ' A new electrophoretic method for determining ligand: Technetium stoichiometry in carrier free 99m Tc-radiopharmaceuticals ', Journal of Nuclear Medicine , vol. 20, no. 8, pp. 871-876. (elsevier.com)
  • The myocardial transmicrovascular transport of thallium-201 (201Tl) and technetium-99m hexakis(2-methoxyisobutylisonitrile) (MIBI) were compared during variable blood flow levels in nine blood-perfused, isolated rabbit hearts. (ahajournals.org)
  • Technetium-99 has a fission product yield of 6.0507% for thermal neutron fission of uranium-235 . (wikipedia.org)
  • Technetium is the only element below uranium that does not exist on Earth . (encyclopedia.com)
  • Naturally occurring technetium is a spontaneous fission product in uranium ore and thorium ore, the most common source, or the product of neutron capture in molybdenum ores. (wikipedia.org)
  • Even so, some technetium atoms are produced as uranium undergoes nuclear fission and there is about 1 milligram of technetium in a tonne of uranium. (rsc.org)
  • Most technetium produced on Earth is a by-product of fission of uranium-235 in nuclear reactors and is extracted from nuclear fuel rods. (newworldencyclopedia.org)
  • Since technetium is unstable, only minute traces occur naturally in the Earth 's crust as a spontaneous fission product of uranium . (newworldencyclopedia.org)
  • In 1999 David Curtis (see above) estimated that a kilogram of uranium contains 1 nanogram (1×10 −9 g) of technetium. (newworldencyclopedia.org)
  • The fission of a gram of the rare isotope uranium-235 in nuclear reactors yields 27 mg of 99 Tc, giving technetium a fission yield of 6.1 percent. (newworldencyclopedia.org)
  • Technetium can be found in nuclear reactor waste and at sites that processed uranium for nuclear weapons during the Cold War, such as the Hanford Site in Washington State. (phys.org)
  • U.S. regulators are giving the green light to a new technology to produce technetium-99m, the most widely used radioisotope for medical imaging, without relying on weapons-grade highly enriched uranium. (acs.org)
  • LEU TechneLite ® (Technetium Tc 99m Generator) is the first Tc-99m generator in the United States to contain at least 95 percent Low Enriched Uranium (LEU)-sourced molybdenum-99 (Mo-99), meeting the Centers for Medicare and Medicaid Services (CMS) criteria for the incremental add-on HOPPS payment. (lantheus.com)
  • The rare earths, technetium and the actinides (especially uranium, plutonium and americium), are extracted from the aqueous phase using a phosphine oxide in a hydrocarbon diluent, and reextracted from the resulting organic phase into an aqueous phase by using a suitable strip reagent. (energy.gov)
  • The Middle East and Africa technetium-99m market is projected to expand at an 8.1% CAGR from 2016 to 2026. (transparencymarketresearch.com)
  • Country-wise, Egypt led the market in 2016 and is further expected to retain a strong foothold in the Middle East and Africa technetium-99m market by the end of 2026 with a valuation of US$110.1 mn in the same year. (transparencymarketresearch.com)
  • Technetium is now produced in nuclear reactors. (encyclopedia.com)
  • It is estimated that up to 1994, about 49,000 TBq (78 metric tons) of technetium was produced in nuclear reactors, which is by far the dominant source of terrestrial technetium. (newworldencyclopedia.org)
  • For this reason, the environmental chemistry of technetium is an active area of research. (wikipedia.org)
  • Researchers revealed in Communications Chemistry that clusters of technetium partially incorporate into iron minerals, such as magnetite, during simultaneous iron oxidation and mineralization. (phys.org)
  • Spontaneous redox continuum reveals sequestered technetium clusters and retarded mineral transformation of iron, Communications Chemistry (2020). (phys.org)
  • This review describes recent developments in the chemistry of both first and second generation 99m-technetium-based imaging agents. (rsc.org)
  • Researchers revealed in the Nature Research journal Communications Chemistry that clusters of technetium partially incorporate into iron minerals, such as magnetite, during simultaneous iron oxidation and mineralization. (pnnl.gov)
  • I want to get the latest chemistry news from C&EN in my inbox every week. (acs.org)
  • They eventually gave the name technetium to the element, from the Greek word technetos, meaning "artificial. (encyclopedia.com)
  • In 1937, technetium (specifically the technetium-97 isotope) became the first predominantly artificial element to be produced, hence its name (from the Greek τεχνητός, meaning "artificial", + -ium). (wikipedia.org)
  • The present investigation was focused on developing Technetium-99m (⁹⁹(m)Tc)-labeled poly(dl-lactide-co-glycolide) (PLGA) nanoparticles as an alternative to ⁹⁹(m)Tc-labeled sulfur colloid/albumin nanocolloid for sentinel lymph node detection. (nih.gov)
  • de Bois M.H.W., Arndt J.W., van der Velde E.A., Pauwels E.K.J., Breedveld F.C. (1994) Comparison of Technetium-99m-Labelled Human Polyclonal Immunoglobulin Scintigraphy with Conventional Bone Scintigraphy in Patients with Rheumatoid Arthritis and Osteoarthritis. (springer.com)
  • This transmutation process bombards the technetium ( 99 Tc as a metal target) with neutrons , forming the short-lived 100 Tc (half-life = 16 seconds) which decays by beta decay to stable ruthenium ( 100 Ru). (wikipedia.org)
  • Technetium Tc99m decays by isomeric transition with a physical half-life of 6.02 hours 1 . (rxlist.com)
  • The most prevalent form of technetium-called pertechnetate-is water soluble and has a high potential for spreading through the soil and groundwater. (phys.org)
  • Once lodged within the crystalline structure , the technetium does not re-oxidize back to its more mobile form of pertechnetate-it is instead sequestered for the long term, which minimizes the risk of release back into the groundwater or subsurface environment. (phys.org)
  • Technetium-99m was obtained as pertechnetate by elution of Ultra-TechneKow generator (Mallinckrodt) with sterile 0.9% sodium chloride (Mallinckrodt, The Netherlands). (thefreedictionary.com)
  • The objective was to investigate the effect of Roux-en-Y gastric bypass (RYGB) on biodistribution of sodium pertechnetate (Na 99m Tc - ) in organs and tissues of rats. (scielo.br)
  • A technique for performing thyroid scintigrapy in the cat using technetium 99m pertechnetate is presented. (avmi.net)
  • The effect of hyperthermia on the accumulation of technetium-99m-labeled liposomes was studied in feline sarcomas. (aacrjournals.org)
  • The first was used to quantify the amount of technetium-99m-labeled liposomes within the tumor under normothermic conditions. (aacrjournals.org)
  • Planar scintigraphy was used to measure the activity of technetium-99m-labeled liposomes within the tumor at predetermined times up to 18 h after injection. (aacrjournals.org)
  • The purpose of this study was to determine if a small tracer dose of technetium-99m ( 99m Tc)-labeled liposomes could be used to quantify the effect of local hyperthermia on intratumoral Doxil extravasation. (aacrjournals.org)
  • Liposomes of approximately same size and composition as Doxil were radiolabeled using [technetium-99m ( 99m Tc)]exametazime. (aacrjournals.org)
  • Technetium-99m labelled liposomes to image experimental arthritis. (semanticscholar.org)
  • OBJECTIVES Liposomes sterically stabilised with polyethylene glycol (PEG) labelled with technetium-99m were tested for their ability to image adjuvant arthritis in a rat model. (semanticscholar.org)
  • Distribution of technetium-99m PEG-liposomes during oligofructose-induced laminitis development in horses. (semanticscholar.org)
  • Detecting infection and inflammation with technetium-99m-labeled Stealth liposomes. (semanticscholar.org)
  • In sentinel biopsy, radiolabelled technetium is injected into the tumor or surrounding lung, and a gamma camera is used to detect the nodes that the cancer is most likely to spread to first. (oxforddictionaries.com)
  • Technetium was discovered by Emilio Segrè in 1937 in Italy. (rsc.org)
  • Technetium was the first element to be created artificially, in 1937, by bombarding molybdenum with deuterons. (oxforddictionaries.com)
  • Technetium was prepared artificially in 1937 by the Italian scientists E. Segré and C. Perrier during the deuteron bombardment of molybdenum nuclei. (thefreedictionary.com)
  • INTERNATIONAL ATOMIC ENERGY AGENCY, Non-HEU Production Technologies for Molybdenum-99 and Technetium-99m, Nuclear Energy Series No. NF-T-5.4, IAEA, Vienna (2013). (iaea.org)
  • Technetium-99m can be produced by molybdenum-99 and molybdenum-100 but the both sources are utilized by two different manufacturing process i.e. from nuclear reactor on a large scale and from cyclotron & accelerator on a small scale governed by any hospital facility. (researchmoz.us)
  • Direct detection of regional myocardial ischemia with technetium-99m nitroimidazole in rabbits. (umassmed.edu)