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Penicillanic AcidPiperacillinSodiumClavulanic Acidbeta-LactamasesSulbactamAnti-Bacterial AgentsSodium ChannelsClavulanic AcidsMicrobial Sensitivity Testsbeta-LactamsPenicillinsCephalosporinsEnterobacter cloacaeDrug Therapy, CombinationGram-Negative BacteriaSodium, DietaryCeftazidimeTicarcillinSodium ChlorideCephalosporinaseEnzyme Inhibitorsbeta-Lactam ResistanceKlebsiella pneumoniaeBacterial InfectionsLuxembourgCitrobacter freundiiKlebsiella InfectionsPseudomonas aeruginosaCarbapenemsImipenemMannansGram-Negative Bacterial InfectionsDrug Resistance, Multiple, BacterialChemotherapy-Induced Febrile NeutropeniaBacteriaSodium Channel BlockersSodium IsotopesEnterobacteriaceaeThienamycinsCross InfectionPseudomonas InfectionsSodium Dodecyl SulfateEscherichia coliSodium BicarbonateAbdominal AbscessBlisterIsoelectric FocusingBacteroides fragilisKlebsiellaMonobactamsDrug Resistance, BacterialCefoxitinKineticsPremedicationEscherichia coli InfectionsEpithelial Sodium ChannelsSodium NitriteDrug CombinationsLactamsSodium CompoundsAcinetobacterBacteria, AnaerobicCephalosporin ResistanceAnti-Infective AgentsSodium SalicylateCromolyn SodiumFalse Positive ReactionsCeftriaxoneGram-Positive BacteriaEnterobacteriaceae InfectionsSodium AzideDrug Resistance, MicrobialAcinetobacter baumanniiInfusions, IntravenousRectumThighCiprofloxacinHalf-LifeDrug SynergismExudates and TransudatesTobramycinHuman ExperimentationPenicillinaseSodium HypochloriteLegionellaPeritonitisPotassiumSodium AcetatePneumonia, BacterialSodium Chloride, DietaryWound InfectionArea Under CurveChromatography, High Pressure LiquidNAV1.5 Voltage-Gated Sodium ChannelMetabolic Clearance RateAspergillosisHospitalsIntensive Care UnitsDiet, Sodium-Restricted

INJECTION500mgPiperacillin Sodium and Tazobactam SodiumCeftolozaneValproic acid or divalproex sodiumBeta-lactamasePENICILLINSPowderAntibiotic piperacillinPenicillanic acidPseudomonas1000mgInhibitorANTIBACTERIALDosageBacterial resistanceStabilityAntibioticsPharmaceutical drugConcentrationPenicillinSpectrumPatientsReactionsInfectionsKidneyMedicineFormulationBody

INJECTION3

• Co-administration of Ertapenem for injection with valproic acid or divalproex sodium reduces the serum concentration of valproic acid potentially increasing the risk of breakthrough seizures. (nih.gov)
• Piperacillin/Tazobactam (Vigocid) 2 g/250 mg Lyophilized Sterile Powder for Injection is a white to off-white powder, supplied in a Type III clear and colorless glass vial with rubber stopper and green aluminium seal. (cathaydrug.com)
• These antibacterial drugs are offered in different types of injections such as Amoxycillin 250mg and Potassium Clavulanic Acid 50mg Injection, Ampicillin 500mg Injection , Piperacillin Sodium 4 gm and Tazobactam 500 mg, Cefazoline Sodium 500 mg, Cefoperazone 500 mg Injection and many more in the list. (lexicarepharma.com)

500mg3

• CEFOBACT 1G-2G 1G has Cefoperazone Sodium, U.S.P=500mg of Cefoperazone & Sulbactam Sodium U.S.P=500mg of Sulbactam. (csc-pharmaceuticals.com)
• CLAVUBACT 600-1200-600 Amoxycillin Sodium U.S.P=500mg of Amoxycillin and Pottasium Clavulanate U.S.P=Clavulanic Acid 100mg. (csc-pharmaceuticals.com)
• AMPIBACT Ampicillin Sodium U.S.P=1000 mg of Ampicillin and Sulbactam Sodium U.S.P=500mg of Sulbactam. (csc-pharmaceuticals.com)

Piperacillin Sodium and Tazobactam Sodium2

• This article compares the effects of three different methods on dissolving piperacillin sodium and tazobactam sodium for infection to improve nursing efficiency. (actamedicamediterranea.com)
• Piperacillin sodium and tazobactam sodium, the method of holding bottle, dissolution. (actamedicamediterranea.com)

Ceftolozane2

• PUBLISHED MANUSCRIPT: Assessment of ceftolozane/tazobactam stability in elastomeric devices and suitability for continuous infusion via outpatient parenteral antimicrobial therapy. (icdst.co.uk)
• Title: Assessing the stability of ceftolozane/tazobactam (ZERBAXA®) at 5 mg/mL and 20 mg/mL following reconstitution and dilution in 0.9% saline in two commercially available elastomeric devices. (icdst.co.uk)

Valproic acid or divalproex sodium1

• Increased Seizure Potential Due to Interaction with Valproic Acid: Concomitant use of RECARBRIO with valproic acid or divalproex sodium may reduce the serum concentration of valproic acid which may increase the risk of breakthrough seizures. (nih.gov)

Beta-lactamase2

• Its spectrum of activity is widened by administration with the beta-lactamase inhibitor tazobactam. (cathaydrug.com)
• Tazobactam is a beta-lactamase inhibitor, which helps reduce bacterial resistance and boosts the effectiveness of Piperacillin against bacteria. (mrmed.in)

PENICILLINS1

• Do not use Piperacillin + Tazobactam if you are allergic to Piperacillin, Tazobactam, penicillins, cephalosporins, other beta-lactamase inhibitors, or any of its ingredients. (mrmed.in)

Powder2

• Piperacillin / tazobactam parenteral combination (VIGOCID), is a white powder consisting of piperacillin and tazobactam as their sodium salts. (cathaydrug.com)
• Piperacillin/Tazobactam powder for Inj. (gov.on.ca)

Antibiotic piperacillin2

• Tazobactam is combined with the extended spectrum β-lactam antibiotic piperacillin in the drug piperacillin/tazobactam, used in infections due to Pseudomonas aeruginosa. (wikipedia.org)
• Piperacillin / tazobactam are antibacterial combination for intravenous administration which consists of semi synthetic antibiotic piperacillin sodium and a ß-lactamase inhibitor tazobactam sodium. (cathaydrug.com)

Penicillanic acid1

• An antibiotic combination product of piperacillin and tazobactam, a penicillanic acid derivative with enhanced beta-lactamase inhibitory activity, that is used for the intravenous treatment of intra-abdominal, pelvic, and skin infections and for community-acquired pneumonia of moderate severity. (bvsalud.org)

Pseudomonas1

• Nosocomial pneumonia (moderate to severe) caused by β-lactamase producing isolates of Staphylococcus aureus and by piperacillin/tazobactam-susceptible Acinetobacter baumannii , Haemophilus influenzae , Klebsiella pneumoniae , and Pseudomonas aeruginosa (Nosocomial pneumonia caused by P. aeruginosa should be treated in combination with an aminoglycoside) [ see Dosage and Administration (2) ]. (sdrugs.com)

1000mg2

• PIPRACILIN 1G-2G-4G Piperacillin Sodium U.S.P=Piperacillin U.S.P 1000mg +W.F.I, for 2G & 4G it has 2000mg +W.F.I & 4000mg +W.F.I. resp. (csc-pharmaceuticals.com)
• Cefpirome Sulphate=1000mg Cefpirome and Sodium-carbonate. (csc-pharmaceuticals.com)

Inhibitor1

• Alpit is a combination product consisting of a penicillin-class antibacterial, piperacillin, and a β-lactamase inhibitor, tazobactam, indicated for the treatment of patients with moderate to severe infections caused by susceptible isolates of the designated bacteria in the conditions listed below. (sdrugs.com)

ANTIBACTERIAL1

• Tazobactam is metabolized to a single metabolite that lacks pharmacological and antibacterial activities. (cathaydrug.com)

Dosage3

• Initial presumptive treatment of patients with nosocomial pneumonia should start with Alpit at a dosage of 4.5 g every six hours plus an aminoglycoside, totaling 18.0 g (16.0 g piperacillin/2.0 g tazobactam). (sdrugs.com)
• For children with appendicitis and/or peritonitis the recommended Alpit dosage is 100 mg piperacillin/12.5 mg tazobactam per kilogram of body weight, every 8 hours in pediatric patients 9 months of age and older. (sdrugs.com)
• For pediatric patients 2 to 9 months of age, the recommended dosage is 80 mg piperacillin/10 mg tazobactam per kilogram of body weight, every 8 hours. (sdrugs.com)

Bacterial resistance1

• Highly effective against a broad range of bacteria through antibiotic activity of piperacilline associated with tazobactam avoiding bacterial resistance and increasing local AB activity. (medtechdental.com)

Stability1

• PUBLISHED MANUSCRIPT: Assessment of the stability of citrate-buffered piperacillin/tazobactam for continuous infusion when stored in two commercially available elastomeric devices for outpatient parenteral antimicrobial chemotherapy: a study compliant with the NHS Yellow Cover Document requirements. (icdst.co.uk)

Antibiotics3

• Group A re- different antibiotics on the outcome of sur- ceived piperacillin sodium/tazobactam so- gical care. (who.int)
• Tazobactam has the potential to extend the spectrum of activity to beta-lactam antibiotics against beta-lactamase-producing bacteria. (cathaydrug.com)
• Piperacillin + Tazobactam which belongs to the medication class known as broad-spectrum penicillin antibiotics and beta-lactamase inhibitors. (mrmed.in)

Pharmaceutical drug2

• Tazobactam is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. (wikipedia.org)
• Citicoline Sodium is a pharmaceutical drug that is considered as the nutritional supplement with a good amount of choline which is an essential nutrient to improve body metabolism. (anglebiopharma.com)

Concentration1

• mented with 4 µg/mL of tazobactam (final concentration). (cdc.gov)

Penicillin1

• Piperacillin sodium a ureidopenicillin, derived from D(-)-a-aminobenzyl-penicillin. (cathaydrug.com)

Spectrum1

• Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express β-lactamase and would normally degrade piperacillin. (wikipedia.org)

Patients2

• Streptococcus species [ 3 ], although an in- tion as determined by the Wagner classifi- creasing number of patients have been en- cation. (who.int)
• In this trial, treatment-emergent adverse events were reported by 402 patients, 204 (91.9%) in the piperacillin/tazobactam group and 198 (92.1%) in the imipenem/cilastatin group. (druglib.com)

Reactions1

• Serious side effects while taking Piperacillin + Tazobactam are severe anaphylactic reactions, Stevens-Johnson syndrome, toxic epidermal necrosis, progressive rashes, bleeding, anemia, and Clostridium difficile-associated diarrhea. (mrmed.in)

Infections1

• Piperacillin + Tazobactam also treats bacterial infections in children aged 2-12 years, particularly abdomen infections like appendicitis, peritonitis, and gallbladder infections. (mrmed.in)

Kidney1

• Both piperacillin and tazobactam are eliminated via the kidney by glomerular filtration and tubular secretion. (cathaydrug.com)

Medicine1

• Notify your doctor if you are allergic to sodium, as this medicine contains sodium. (mrmed.in)

Formulation1

• Piperacillin sodium is bactericidal in action by inhibiting septum formulation and cell wall synthesis of susceptible bacteria. (cathaydrug.com)

Body2

• Piperacillin and tazobactam are widely distributed in body tissues and fluids. (cathaydrug.com)
• Piperacillin with Tazobactam is used to kill many types of harmful bacteria in our body. (mrmed.in)