Targets downregulation cdk6. Medical search. Frequent questions

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Anatomy29

Cell Line, Tumor Cells, Cultured Cell Line Tumor Cells, Cultured HeLa Cells Fibroblasts Neurons Cell Nucleus HEK293 Cells Epithelial Cells HCT116 Cells Cell Line, Transformed NIH 3T3 Cells Centrosome 3T3 Cells Embryo, Mammalian Myocardium COS Cells Myocytes, Smooth Muscle Keratinocytes Endothelial Cells Kidney Muscle, Smooth, Vascular Stem Cells Cytoplasm Liver Myocytes, Cardiac Mitochondria Brain

Organisms9

Rats, Sprague-Dawley Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Mice, Nude Rats, Wistar Mice, Inbred BALB C Animals, Newborn Cercopithecus aethiops

Diseases9

Disease Models, Animal Cell Transformation, Neoplastic Breast Neoplasms Neoplasm Invasiveness Polyuria Melanoma Disease Progression Colonic Neoplasms Prostatic Neoplasms

Chemicals and Drugs123

Cyclin-Dependent Kinases Cyclin-Dependent Kinase 2 Cyclin-Dependent Kinase 5 Cyclin-Dependent Kinase 4 CDC2-CDC28 Kinases Cyclin-Dependent Kinase 6 CDC2 Protein Kinase Cyclins RNA, Messenger Cyclin-Dependent Kinase Inhibitor p27 Cell Cycle Proteins RNA, Small Interfering Protein-Serine-Threonine Kinases Cyclin-Dependent Kinase 9 Cyclin E Cyclin-Dependent Kinase Inhibitor p21 Cyclin D1 Cyclin D Proto-Oncogene Proteins Cyclin-Dependent Kinase 8 Tumor Suppressor Proteins Transcription Factors MicroRNAs Purines Enzyme Inhibitors Cyclin B Cyclin D3 Microtubule-Associated Proteins Cyclin H Cyclin-Dependent Kinase Inhibitor p16 Nuclear Proteins DNA-Binding Proteins Carrier Proteins Cyclin B1 Tumor Suppressor Protein p53 cdc25 Phosphatases Nerve Tissue Proteins Cyclin-Dependent Kinase Inhibitor p18 Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins c-bcl-2 Cyclin-Dependent Kinase 3 Cyclin T Cyclin C Kinetin Protein Kinase Inhibitors Cyclin D2 Antineoplastic Agents Membrane Proteins Recombinant Fusion Proteins Protein Kinases Proteasome Endopeptidase Complex Oncogene Proteins Repressor Proteins Cyclin-Dependent Kinase Inhibitor Proteins Intracellular Signaling Peptides and Proteins DNA Primers Proto-Oncogene Proteins c-myc Neoplasm Proteins Cadherins nef Gene Products, Human Immunodeficiency Virus Oligonucleotides, Antisense Myeloid Cell Leukemia Sequence 1 Protein Apoptosis Regulatory Proteins Trans-Activators E2F1 Transcription Factor Cyclin-Dependent Kinase Inhibitor p57 E2F Transcription Factors NF-kappa B Homeodomain Proteins Threonine Aquaporin 2 beta Catenin Transforming Growth Factor beta Caspase 3 Cyclin A2 Proteins Caspases Recombinant Proteins Ubiquitin-Protein Ligases Extracellular Signal-Regulated MAP Kinases Inhibitor of Apoptosis Proteins Cyclin-Dependent Kinase Inhibitor p15 Positive Transcriptional Elongation Factor B Tumor Necrosis Factor-alpha Xenopus Proteins Phosphatidylinositol 3-Kinases 3' Untranslated Regions Gene Products, nef Ubiquitin Reactive Oxygen Species Protein Kinase C Histones Drosophila Proteins Cyclin G Phosphoproteins Glycogen Synthase Kinase 3 S-Phase Kinase-Associated Proteins CDC28 Protein Kinase, S cerevisiae Adaptor Proteins, Signal Transducing Protein Isoforms Indoles Oligodeoxyribonucleotides, Antisense Antigens, CD4 Mitogen-Activated Protein Kinases Multiprotein Complexes Saccharomyces cerevisiae Proteins bcl-2-Associated X Protein Cyclin G1 Flavonoids Transforming Growth Factor beta1 Transcription Factor DP1 Pyridines Luciferases Cyclin-Dependent Kinase Inhibitor p19 Receptor, Epidermal Growth Factor bcl-X Protein Solute Carrier Family 12, Member 1 ras Proteins Proliferating Cell Nuclear Antigen DNA Membrane Glycoproteins Actins Protein-Tyrosine Kinases

Analytical, Diagnostic and Therapeutic Techniques and Equipment24

Blotting, Western Reverse Transcriptase Polymerase Chain Reaction Transfection Gene Knockdown Techniques Gene Expression Profiling Real-Time Polymerase Chain Reaction Immunoprecipitation Oligonucleotide Array Sequence Analysis Disease Models, Animal Flow Cytometry Immunoblotting Models, Biological Immunohistochemistry Xenograft Model Antitumor Assays Fluorescent Antibody Technique Blotting, Northern Microscopy, Fluorescence Chromatin Immunoprecipitation Polymerase Chain Reaction In Situ Hybridization Microarray Analysis Microscopy, Confocal Precipitin Tests Electrophoretic Mobility Shift Assay

Phenomena and Processes59

Down-Regulation Cell Cycle Phosphorylation Signal Transduction Apoptosis G1 Phase Cell Proliferation RNA Interference Gene Expression Regulation Gene Expression Regulation, Neoplastic S Phase Up-Regulation Transfection Transcription, Genetic Protein Binding Cell Differentiation Mitosis Promoter Regions, Genetic Enzyme Activation Cell Division Gene Expression Mutation Base Sequence Gene Silencing Cell Movement Cell Survival Cell Cycle Checkpoints Time Factors Amino Acid Sequence Gene Expression Regulation, Developmental G2 Phase Gene Expression Regulation, Enzymologic G1 Phase Cell Cycle Checkpoints Dose-Response Relationship, Drug Phenotype Protein Transport Ubiquitination DNA Methylation DNA Damage Binding Sites G0 Phase Drug Resistance, Neoplasm Protein Structure, Tertiary Transcriptional Activation Protein Processing, Post-Translational 3' Untranslated Regions Cell Death Proteolysis Epithelial-Mesenchymal Transition DNA Replication Cell Adhesion Genes, Reporter MAP Kinase Signaling System Genes, Tumor Suppressor Oxidative Stress Cell Growth Processes Gene Deletion S Phase Cell Cycle Checkpoints Cell Aging

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Down-Regulation Cyclin-Dependent Kinases Cyclin-Dependent Kinase 2 Cyclin-Dependent Kinase 5 Cyclin-Dependent Kinase 4 CDC2-CDC28 Kinases Cyclin-Dependent Kinase 6 Cell Line, Tumor CDC2 Protein Kinase Cell Cycle Cyclins Phosphorylation RNA, Messenger Cyclin-Dependent Kinase Inhibitor p27 Cell Cycle Proteins Signal Transduction RNA, Small Interfering Protein-Serine-Threonine Kinases Apoptosis Cells, Cultured Cyclin-Dependent Kinase 9 G1 Phase Cell Proliferation Cyclin E RNA Interference Blotting, Western Gene Expression Regulation Cell Line Reverse Transcriptase Polymerase Chain Reaction Gene Expression Regulation, Neoplastic Cyclin-Dependent Kinase Inhibitor p21 Cyclin D1 Cyclin D S Phase Proto-Oncogene Proteins Cyclin-Dependent Kinase 8 Tumor Suppressor Proteins Up-Regulation Transfection Transcription Factors MicroRNAs Transcription, Genetic Purines Protein Binding Enzyme Inhibitors Gene Knockdown Techniques Molecular Sequence Data Cell Differentiation Cyclin B Cyclin D3 Mitosis Promoter Regions, Genetic Enzyme Activation Cell Division Rats, Sprague-Dawley Gene Expression Microtubule-Associated Proteins Cyclin H Cyclin-Dependent Kinase Inhibitor p16 Nuclear Proteins Tumor Cells, Cultured Mutation Mice, Inbred C57BL HeLa Cells DNA-Binding Proteins Gene Expression Profiling Mice, Knockout Carrier Proteins Base Sequence Cyclin B1 Gene Silencing Real-Time Polymerase Chain Reaction Tumor Suppressor Protein p53 cdc25 Phosphatases Cell Movement Nerve Tissue Proteins Cell Survival Cell Cycle Checkpoints Immunoprecipitation Cyclin-Dependent Kinase Inhibitor p18 Time Factors Fibroblasts Amino Acid Sequence Oligonucleotide Array Sequence Analysis Disease Models, Animal Proto-Oncogene Proteins c-akt Flow Cytometry Mice, Transgenic Proto-Oncogene Proteins c-bcl-2 Neurons Mice, Nude Cyclin-Dependent Kinase 3 Cyclin T Immunoblotting Cyclin C Models, Biological Kinetin Gene Expression Regulation, Developmental Protein Kinase Inhibitors G2 Phase

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