• Seoul and San Francisco - January 31, 2023 - Pin Therapeutics, a biotech company focused on developing new therapies in the field of E3 ligase and Molecular Glue Degraders, announced today that it has migrated all its R&D data to CDD Vault , an informatics platform developed by Collaborative Drug Discovery, to support its quest for next-generation diagnostics and cures. (collaborativedrug.com)
  • Sept. 19, 2023 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) ("Aprea", or the "Company"), a clinical-stage biopharmaceutical company focused on precision oncology through synthetic lethality, today announced two poster presentations at the upcoming 2023 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics being held on October 11-15, 2023, in Boston, MA. (wjbf.com)
  • Certain Common stock of Protagonist Therapeutics, Inc. are subject to a Lock-Up Agreement Ending on 4-JUN-2023. (marketscreener.com)
  • IMARC Group provides an analysis of the key trends in each segment of the global lung cancer therapeutics market, along with forecasts at the global, regional, and country levels from 2023-2028. (imarcgroup.com)
  • CAMBRIDGE, MA, USA I June 23, 2023 I HiFiBiO Therapeutics, a multinational clinical-stage biotherapeutics company, announced today that the first patient has been dosed with HiFiBiO's HFB200301, a first-in-class agonistic anti-TNFR2 monoclonal antibody, in combination with tislelizumab, an investigational anti-PD-1 immune checkpoint inhibitor, for the treatment of advanced solid tumor indications preselected by HiFiBiO's proprietary Drug Intelligence Science (DIS ® ) platform . (pipelinereview.com)
  • WHO Therapeutics and COVID-19: Living guideline, 13 January 2023, page 12. (who.int)
  • Royal Capital Wealth Management LLC purchased a new position in shares of Revance Therapeutics, Inc. ( NASDAQ:RVNC - Free Report ) during the first quarter, according to the company in its most recent Form 13F filing with the Securities and Exchange Commission (SEC). The fund purchased 6,875 shares of the biopharmaceutical company's stock, valued at approximately $221,000. (etfdailynews.com)
  • Revance Therapeutics ( NASDAQ:RVNC - Get Free Report ) last released its earnings results on Tuesday, August 8th. (etfdailynews.com)
  • Pharmaceutical companies operate in highly competitive, global markets where efforts to develop new targeted therapies and bring them to market require reliable partnerships that can help streamline every process. (thermofisher.com)
  • These biomarkers represent candidates to help elucidate the biology of diseases, to identify the mechanisms for drug resistance, and to design better targeted therapies for precision medicine. (labroots.com)
  • Conclusion: These data are the single largest compilation of NGS analysis on CCA patients and demonstrate the range of GVs that are eligible for investigational targeted therapies. (aacrjournals.org)
  • Apart from this, the development of targeted therapies that offer personalized treatment options and improve patient outcomes are favoring market growth. (imarcgroup.com)
  • Terray Therapeutics today announced the closing of a $60 million Series A financing to advance its novel tNova platform and deliver therapies to patients faster than ever before. (biospace.com)
  • Targeted cancer therapies, on the other hand, capitalize on the quantitative and, more importantly, qualitative differences resulting from the genetic (mutation or copy number alterations) and/or epigenetic (non-structural genetic modifications) changes that rewire the biomolecular cellular network creating new pathways with distinctive fragile gene/protein nodes (see figure 1). (marycrowley.org)
  • FDA-approved targeted therapies are classified as either monoclonal antibodies (MAb) or small molecules. (marycrowley.org)
  • P90 ribosomal S6 kinases: A bona fide target for novel targeted anticancer therapies? (lu.se)
  • We are encouraged by the data from our ongoing studies of STK-001, which continue to demonstrate favorable safety findings and reductions in seizure frequency among a highly refractory group of patients,' said Barry Ticho, M.D., Ph.D., Chief Medical Officer of Stoke Therapeutics. (yahoo.com)
  • Anthony Marucci, President and Chief Executive Officer of Celldex, stated, The CuraGen acquisition fulfills a major initiative to identify, acquire and integrate value-creating, synergistic assets to fuel our Precision Targeted Immunotherapy Platform and enhance Celldex s antibody-based technology pipeline. (salesandmarketingnetwork.com)
  • This interagency group characterizes emerging variants and monitors their potential impact on vaccines, therapeutics, and diagnostics. (cdc.gov)
  • They also assess how these changes may affect vaccines, therapeutics, and diagnostics, as well as transmission and severity of disease. (cdc.gov)
  • This paves the way to therapeutics and vaccines. (cdc.gov)
  • Aprea Therapeutics, Inc. is a clinical-stage biopharmaceutical company headquartered in Doylestown, Pennsylvania, focused on precision oncology through synthetic lethality. (wjbf.com)
  • G1 Therapeutics, Inc. is an American biopharmaceutical company headquartered in Research Triangle Park, North Carolina. (wikipedia.org)
  • Abstract B132: Next generation sequencing yields promising targets in advanced cholangiocarcinoma (CCA). (aacrjournals.org)
  • Next generation sequencing (NGS) technology offers potential for targeted therapeutics against genetically heterogenous solid tumors including cholangiocarcinoma (CCA). (aacrjournals.org)
  • The conference is entitled, "Next-Generation Sequencing for Targeted Therapeutics. (bioquicknews.com)
  • Targeted Whole Exome Sequencing in Children With Early-Onset Epilepsy: Parent Experiences. (cdc.gov)
  • The Company's Interleukin-23 receptor (IL-23R) antagonist compound JNJ-2113 is an orally delivered investigational drug that is designed to block biological pathways targeted by marketed injectable antibody drugs. (marketscreener.com)
  • CR011, currently in Phase 2 studies, is an antibody-drug conjugate that targets GPNMB, a protein that is highly expressed in metastatic breast cancer and melanoma. (salesandmarketingnetwork.com)
  • Celldex s expertise in developing novel antibody-based therapeutics will enable us to seamlessly integrate CuraGen s antibody programs into our Precision Targeted Immunotherapy Platform and selectively identify and advance the candidates we believe hold the most therapeutic promise, said Thomas Davis, M.D., Chief Medical Officer of Celldex. (salesandmarketingnetwork.com)
  • Its proprietary and versatile DIS ® single-cell platform enables the rapid discovery of novel antibody therapeutics with predictive biomarkers through our internal development programs and strategic collaborations. (pipelinereview.com)
  • The COBRE Center for Targeted Therapeutics (CTT) was created to attract and foster the professional development of talented junior scientists who are motivated to make a difference in the treatment of debilitating diseases. (sc.edu)
  • Targeted therapeutics is research that seeks to develop new and more effective classes of drugs against various diseases by aiming these drugs at molecular and cellular targets that play a key role in the disease. (sc.edu)
  • The Center for Targeted Therapeutics currently supports four research projects led by junior faculty members with expertise in cancer biology and genomics, signal transduction, metabolic diseases and nanotechnology-based drug delivery. (sc.edu)
  • Through pilot projects and collaborative studies, CTT research will encompass targeted therapeutics for multiple diseases. (sc.edu)
  • Jnana is focusing on immunometabolism, lysosomal function and mucosal defense, important disease pathways where SLC transporters provide novel targets for immuno-oncology, inflammatory disorders and neurological diseases. (businesswire.com)
  • Through a targeted, patient-centric approach to research & development, AbbVie accelerates new scientific discoveries to address some of the most complex diseases and contribute to the sustainability of health care systems around the world. (businesswire.com)
  • Otsuka Pharmaceutical Co., Ltd. (Otsuka) announces that it has entered into a collaboration agreement with xFOREST Therapeutics Co., Ltd. (xFOREST) with the aim to create RNA structure-targeted drugs in multiple diseases. (otsuka.co.jp)
  • Celldex Therapeutics is discovering and developing innovative targeted immunotherapeutics for the treatment of cancer, infectious and inflammatory diseases. (salesandmarketingnetwork.com)
  • Terray Therapeutics and Calico Life Sciences struck a research and development collaboration focused on the development of small-molecule therapeutics for age-related diseases. (biospace.com)
  • HiFiBiO Therapeutics is a clinical stage biotech company advancing a robust pipeline targeting both the innate and adaptive immunity to treat cancer and autoimmune diseases. (pipelinereview.com)
  • Visiting the ER: the endoplasmic reticulum as a target for therapeutics in traffic related diseases. (bvsalud.org)
  • Mizuho boosted their price target on Revance Therapeutics from $33.00 to $35.00 in a research note on Wednesday, June 7th. (etfdailynews.com)
  • Terray Therapeutics is a biotechnology company led by pioneers and long-time leaders in artificial intelligence, synthetic (medicinal) chemistry, biology and preclinical development, automation, and nanotechnology. (biospace.com)
  • Terray Therapeutics, a biotechnology company propelling drug discovery into the information age, today announced the appointment of Fiona Black, PhD to its Scientific Advisory Board, adding valuable expertise in interdisciplinary technology development of both market-leading, end-to-end product solutions and operationally efficient and scalable manufacturing processes. (biospace.com)
  • Terray Therapeutics, a biotechnology company propelling drug discovery into the information age, announced the appointments of Feroze Ujjainwalla, PhD, as Head of Business, and Adam D. Hughes, PhD, as Head of Chemistry. (biospace.com)
  • TG Therapeutics, Inc., a biopharmaceutical company, engages in developing and delivering medicines for patients with chronic lymphocytic leukemia (CLL), non-Hodgkin's Lymphoma (NHL), and multiple sclerosis ( MS ). The company develops a robust B-cell directed research and development platform for identification of key B-cell pathways of interest and rapid clinical testing. (seekingalpha.com)
  • As scientists begin to unravel the genetic and immunological mysteries of psoriasis, a new wave of immunotherapies are being developed that will target specific psoriasis-related immunological pathways without compromising the bodys defense mechanisms. (powershow.com)
  • Despite a bewildering array of potential targets, including mutated and epigenetically modified genes, copy number changes, mRNA splicing differences, and post-translational protein modifications, the vast number of nodes can be classified into one or more of 12 major pathways, the interaction of which confer an adaptation advantage to the evolving cancer (see figure 2). (marycrowley.org)
  • Otsuka will have exclusive rights to develop and commercialize RNA-targeted small molecules identified from the collaboration. (otsuka.co.jp)
  • Patients and oncologists at Mary Crowley Cancer Research have significantly contributed to the development and final FDA approval of a wide variety of personalized cancer therapeutics with 1,629 patients treated with small molecules and 192 patients with MAb in Phase I and II trials through 2014 via coordinated efforts with strategic partners (see table 1). (marycrowley.org)
  • The Company s focus is on the use of tumor-specific targets and human monoclonal antibodies to precisely deliver therapeutic agents through their novel targeted immunization approach. (salesandmarketingnetwork.com)
  • Please use the tools below to analyze the current value of Addex Therapeutics in the context of predictive analytics. (macroaxis.com)
  • Are you surprised that targeted therapeutics for metastatic renal cell carcinoma (RCC) have not improved survival? (renalandurologynews.com)
  • Targeted therapeutic agents for treating metastatic RCC has not led to an improved survival. (renalandurologynews.com)
  • A study published recently in Urologia Internationalis (online ahead of print) found that the advent of targeted therapeutic agents for treating metastatic renal cell carcinoma (RCC) -which began with the FDA approval of sorafenib in 2005-has not led to an improvement in survival rates. (renalandurologynews.com)
  • Precision public health uses a wide array of big data, including genomics and other biological markers, other digital information, and wearables (e.g. smart watch) to provide more precision in assessing public health burden and needs and developing targeted interventions to communities and subpopulations, that collectively can benefit the entire population and address health disparities. (cdc.gov)
  • Beyond genomics, granular data from public health surveillance are being used to target public health interventions. (cdc.gov)
  • Pin Therapeutics (www.pintherapeutics.com, "Pin") is a biotech company in Targeted Protein Degradation (TPD) field and located in South Korea and SF. (collaborativedrug.com)
  • The PowerPoint PPT presentation: "U.S. Emerging Psoriasis Therapeutics Markets Targeted Immunotherapies Define Future of the Field" is the property of its rightful owner. (powershow.com)
  • Pin focuses on Targeted Protein Degradation (TPD) technology and is developing two types of drugs: PROTAC (PROteolysis-TArgeting Chimera) and Molecular Glue Degrader. (collaborativedrug.com)
  • We hope that this collaboration will lead to the development of new small molecule drugs that directly target RNA through the utilization of xFOREST's unique technology platform. (otsuka.co.jp)
  • Through this collaboration on a new disease target, we will strive to be a driving force for the development of therapeutic drugs as soon as possible. (otsuka.co.jp)
  • In the last two decades several integrin-targeted drugs have made their way into clinical use, many others are in clinical trials and still more are showing promise as they advance through preclinical development. (thno.org)
  • Candida show uniform resistance to a wide spectrum of the The devices become colonized by the microorganisms that currently available conventional antifungal agents, which form a biofilm of cells, the detachment of which can result implies that antimicrobial drugs that specifically target in septicemia (2-5,8,9,14,15). (cdc.gov)
  • Current public health events of drugs directly target specific viruses. (who.int)
  • 7 579 071 (145 054) 1.9%] these drugs interact in particular ways recommendations have added Republic of) with targets in the body. (who.int)
  • Jnana's proprietary small molecule platform allows the company to address therapeutic targets rapidly and comprehensively across the SLC transporter family. (businesswire.com)
  • TG Therapeutics, Inc., a biopharmaceutical company, engages in developing and delivering medicines for patients with chronic lymphocytic leukemia (CLL), non-Hodgkin's Lymphoma (NHL), and multiple sclerosis (MS). (seekingalpha.com)
  • Magellan Rx Management, a Prime Therapeutics LLC Company, is a pioneer in specialty and medical drug management and a leader in serving public sector state government programs. (primetherapeutics.com)
  • Protagonist Therapeutics, Inc. is a biopharmaceutical company. (marketscreener.com)
  • Morgan Stanley dropped their price objective on shares of Revance Therapeutics from $26.00 to $25.00 and set an "equal weight" rating for the company in a research note on Wednesday, August 9th. (etfdailynews.com)
  • Finally, BNP Paribas upgraded shares of Revance Therapeutics from an "underperform" rating to a "neutral" rating and set a $20.00 price target for the company in a research report on Wednesday, August 16th. (etfdailynews.com)
  • The company specializes in developing and commercializing small molecule therapeutics for the treatment of patients with cancer. (wikipedia.org)
  • Terray Therapeutics today announced that John Maraganore, Ph.D., former founding CEO of Alnylam Pharmaceuticals, has been appointed as Strategic Advisor to the Board of Directors and Leadership Team. (biospace.com)
  • Analysts publish ratings and price targets on most stocks. (benzinga.com)
  • The highest, average, and lowest price target of all analysts. (tipranks.com)
  • On average, sell-side analysts predict that Revance Therapeutics, Inc. will post -2.8 EPS for the current year. (etfdailynews.com)
  • Headquartered in Boston, Massachusetts, Jnana Therapeutics Inc. was launched in 2017 with $50 million in Series A financing from investors including Polaris Partners, Avalon Ventures, Versant Ventures, AbbVie Ventures and Pfizer R&D Innovate. (businesswire.com)
  • Through a logically designed library and screening technique, Pin is developing new molecular glue degraders and platform technologies that can efficiently identify and selectively degrade target proteins. (collaborativedrug.com)
  • and Exploit cancer vulnerabilities by leveraging synthetic lethalities as new "targeted" therapy for cancer. (utsouthwestern.edu)
  • Lung cancer therapeutics refer to various treatment options used for managing and treating the symptoms of lung cancer, which include shortness of breath, chest pain, wheezing, and coughing up blood. (imarcgroup.com)
  • At present, the growing prevalence of lung cancer on account of the increasing consumption of smoking products, rising pollution level, and unhealthy dietary patterns is catalyzing the demand for effective lung cancer therapeutics. (imarcgroup.com)
  • The report has provided a detailed breakup and analysis of the lung cancer therapeutics market based on the therapy. (imarcgroup.com)
  • Vivace Therapeutics Inc. has synthesized transcriptional coactivator YAP1/TEAD and/or TAZ/TEAD interaction inhibitors reported to be useful for the treatment of cancer, polycystic kidney and hepatic fibrosis. (bioworld.com)
  • Having the first patient dosed with HFB200301 and tislelizumab combination therapy is a significant milestone for HiFiBiO," commented Liang Schweizer, PhD, Founder, CEO, and Chairperson of HiFiBiO Therapeutics, "This marks a major step toward further understanding the therapeutic activity of HFB200301 and how we can best deliver safe and effective treatment strategies for cancer patients where other therapeutic options have failed. (pipelinereview.com)
  • G1 Therapeutics was co-founded in 2008 by Norman Sharpless, 15th Director of the National Cancer Institute, and Kwok-Kin Wong, to develop and commercialize drug candidates discovered at, and licensed from, Sharpless' lab at the University of North Carolina at Chapel Hill. (wikipedia.org)
  • The drug's first targeted indication is small cell lung cancer (SCLC). (wikipedia.org)
  • The Americas region dominates the head and neck cancer therapeutics market due to the growing prevalence of head and neck cancer, incidence of a major patient population, high healthcare spending, sophisticated technology and the incidence of chief market companies. (medgadget.com)
  • The European region holds the next position in the global head and neck cancer therapeutics market. (medgadget.com)
  • It is anticipated that the research and development spending offered by the private organizations and government, growing healthcare expenses, growing competition among marketers and adjustments in reimbursement policies in healthcare are expected to guide the European region's head and neck cancer therapeutics market. (medgadget.com)
  • The Asia Pacific region is a rapidly increasing head and neck cancer therapeutics market due to an growing demand, enormous patient pool and the advancement of healthcare technology. (medgadget.com)
  • The Middle East and Africa region retain the least share of the head and neck cancer therapeutics market globally due to deficiency of technical knowledge, low growth and impoverished medical facilities. (medgadget.com)
  • Both surgery and radiation, to some extent, geographically target cancer but are spatially localized and regionally limited by surrounding normal tissue damage, which can result in adverse side effects. (marycrowley.org)
  • As a result, the goal is to identify the dominant pathway[s] amongst the 12 in an individual cancer and target the rate-limiting nodes therein. (marycrowley.org)
  • The MAbs target specific antigens on the cancer cell surface, generally transmembrane receptors that initiate a signaling cascade. (marycrowley.org)
  • The Experimental Therapeutics (ET) Program provides an organized integrated infrastructure that enables both clinical translation of basic and population science research from Simmons research programs and identification of clinically relevant hypotheses for testing by the Center's basic science programs. (utsouthwestern.edu)
  • FOMO, can cause potential investors in Addex Therapeutics to buy its stock at a price that has no basis in reality. (macroaxis.com)
  • Please note, a large amount of money has been lost over the years by many investors who confused the symmetrical distributions of Stock prices, such as prices of Addex Therapeutics, with the unreliable approximations that try to describe financial returns. (macroaxis.com)
  • Safe handling of oral antineoplastic medications: focus on targeted therapeutics in the home setting. (cdc.gov)
  • This topic was chosen because of its societal impact, the emergence of common technologies driving therapeutics research in different disease areas and the presence of a critical core of senior faculty with broad acumen and transdisciplinary vision in targeted therapeutics. (sc.edu)
  • The Center for Targeted Therapeutics at the University of South Carolina is funded by a Center of Biomedical Research Excellence (COBRE) grant from the National Institutes of Health. (sc.edu)
  • Your research has to be compared to or analyzed against Addex Therapeutics' peers to derive any actionable benefits. (macroaxis.com)
  • Our research has great potential for the identification of new therapeutic targets. (indiaeducationdiary.in)
  • StockNews.com began coverage on shares of Revance Therapeutics in a research note on Thursday, August 17th. (etfdailynews.com)
  • Piper Sandler increased their target price on shares of Revance Therapeutics from $39.00 to $50.00 in a research report on Wednesday, May 10th. (etfdailynews.com)
  • According to data from MarketBeat.com, the stock currently has a consensus rating of "Moderate Buy" and a consensus price target of $40.00. (etfdailynews.com)
  • According to the report, targeted therapy represented the largest segment. (imarcgroup.com)
  • The time period 2006-2009 represented the era of targeted RCC therapy. (renalandurologynews.com)
  • When people said, 'Targeted therapy is going to work for all advanced cancers,' they forgot that simple precept: You have to start earlier. (medscape.com)
  • Shunichi Kashida Ph.D., Representative Director and CEO at xFOREST, said, "xFOREST Therapeutics has been expanding its proprietary RNA-targeted drug discovery technology centered on FOREST, a large-scale, small molecule discovery technology targeting RNA structures. (otsuka.co.jp)
  • Researchers at the Center for Targeted Therapeutics are working for the future of South Carolina by developing novel cures that will improve the health of our communities. (sc.edu)
  • BRD4 methylation determines the recruitment of the transcription factor E2F1 to selected target genes which are involved in protein generation, a molecular mechanism which facilitates the balanced expression of these genes. (indiaeducationdiary.in)
  • Further, the median RRs were higher for targeted genomic alterations than for protein aberrations (overexpression), 42% versus 22.4% (p=0.001), respectively. (marycrowley.org)
  • However, the emergence and spread of hypervirulent and multi-resistant strains of this bacterium have recently extended its potential targets to people with no health problems. (krqe.com)