• In order to address these issues as early as possible, a process called tandem mass spectrometry (MS/MS) can be used as it allows for rapid and simultaneous detection of the diseases. (cdc.gov)
  • RÉSUMÉ Le programme national de dépistage néonatal aux Émirats arabes unis couvre actuellement 16 maladies ou troubles : l'hyperthyroïdie congénitale, la drépanocytose, l'hyperplasie congénitale des surrénales, le déficit en biotinidase ainsi que 12 troubles des acides aminés, organiques et gras. (who.int)
  • The first publication of a computer algorithm for tandem MS newborn screening set the upper limit of the reference interval at the 99.5 percentile, which would give 0.5% positives for each analyte, which is reasonable for a single analyte test and disorder ( 12 ). (aaccjnls.org)
  • PerkinElmer Inc., of Wellesley, Mass., and Waters Corp., of Milton, have announced a long-term collaboration to deliver and support advanced newborn screening systems, combining Waters' mass spectrometry and liquid chromatography instruments and control software with PerkinElmer's laboratory information management software. (photonics.com)
  • New approaches to sample preparation and data interpretation have helped establish the methodology as a robust, high-throughput neonatal screening method. (aaccjnls.org)
  • Methods of screening for IEM by tandem mass spectrometry (MS/MS) have been developed, and their advantages include rapid testing, high sensitivity, high specificity, high throughput, and low sample volume (a single dried blood spot). (biomedcentral.com)
  • Historically, each disorder to be screened required a separate test with associated costs and requirement for a portion of the dried-blood-spot specimen from a heel stick. (aaccjnls.org)