Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. (wikipedia.org)
Finally, fibrinolytic effects of MMP-10 and rivaroxaban were evaluated by thromboelastometry and thrombin-activatable fibrinolysis inhibitor (TAFI) activation assays. (unav.edu)
Protein encoded3
The protein encoded by this gene is activated by thrombin and acts on carboxypeptidase B substrates. (wikipedia.org)
Tissue factor , also called platelet tissue factor , factor III , or CD142 is a protein encoded by the F3 gene , present in subendothelial tissue and leukocytes . (wikidoc.org)
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. (cromauv.org)
Coagulation2
Characterization of the human blood coagulation factor XII gene. (wikidoc.org)
The F3 gene encodes coagulation factor III which is a cell surface glycoprotein . (wikidoc.org)
Fibrinolytic1
Finally, we found that CM-352 reduced MMP-10 and rivaroxaban-related fibrinolytic effects in thromboelastometry and TAFI activation. (unav.edu)
Humans2
In humans, factor XII is encoded by the F12 gene . (wikidoc.org)
Description: Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene. (cromauv.org)
Analyses1
Available sequence data analyses indicate splice variants that encode different isoforms. (wikipedia.org)
Transcription3
which have a variety of binding sites for sequence-specific transcription factors and specify characteristic chromatin structures mediated by nucleosome positioning specific histone modifications histone variants and other factors (1 2 For the transcription of type-I interferon (IFN)-stimulated genes (ISGs) promoters containing sequence motifs known as IFN-stimulated response element (ISRE) are the binding sites of the sequence-specific transcription factors activated by IFN stimulation. (techblessing.com)
As proteins encoded by not only have anti-viral activities but also affect host-cellular events (5) the ISG transcription needs to be silenced in the IFN-unstimulated condition. (techblessing.com)
Cis-acting DNA sequences which can increase transcription of genes. (lookformedical.com)
Chromosome2
[ 1 ] As this gene is carried on the X chromosome, the disease usually manifests in males and is transmitted by females who carry the causative mutation on one of their X chromosomes. (medscape.com)
The gene for factor XII is located on the tip of the long arm of the fifth chromosome (5q33-qter). (wikidoc.org)
Factor2
The most frequent causes of an inherited (primary) hypercoagulable state are the factor V Leiden mutation and the prothrombin gene mutation, which together account for 50 to 60 percent of cases. (medilib.ir)
[6] Mice lacking the gene for factor XII, however, are less susceptible to thrombosis . (wikidoc.org)
CPB22
Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. (wikipedia.org)
Pro-carboxypeptidase B2 (pro-CPB2) or thrombin-activatable fibrinolysis inhibitor (TAFI) is a glycoprotein encoded by the CPB2 gene and deregulated in several cancer types, including breast cancer. (nih.gov)
Inhibitor1
10. Characterization of cis-regulatory elements of the vascular endothelial growth inhibitor gene promoter. (nih.gov)
Characterization2
3. Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites. (nih.gov)
4. Cloning and characterization of the human beta2-glycoprotein I (beta2-GPI) gene promoter: roles of the atypical TATA box and hepatic nuclear factor-1alpha in regulating beta2-GPI promoter activity. (nih.gov)
Protein7
The protein encoded by this gene is activated by thrombin and acts on carboxypeptidase B substrates. (wikipedia.org)
13. Identification and analysis of the human neural polypyrimidine tract binding protein (nPTB) gene promoter region. (nih.gov)
The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. (nih.gov)
Description of the protein which includes the UniProt Function and the NCBI Gene Summary. (nih.gov)
While other PD-associate genes, such as LRRK2 , SNCA , and GBA1 , regulate lysosomal functions, lipid metabolism, or protein aggregation, some have been shown to indirectly affect the electron transport chain. (frontiersin.org)
Description: In humans, profillagrin is encoded by the FLG gene, which is part of the S100 fused-type protein (SFTP) family within the epidermal differentiation complex on chromosome 1q21. (herpes-pics.com)
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. (herpes-pics.com)
Promoter region1
Polymorphisms have been described for this gene and its promoter region. (wikipedia.org)
Mutations2
In afibrinogenemia, most mutations of the three encoding genes of fibrinogen chains are null. (mhmedical.com)
Mutations in this gene are associated with ichthyosis vulgaris. (herpes-pics.com)
Variants1
Available sequence data analyses indicate splice variants that encode different isoforms. (wikipedia.org)
PINK11
5. Upregulation of human PINK1 gene expression by NFκB signalling. (nih.gov)