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  • SCID
  • Although adoptive transfer experiments have shown, for the most part, that both CD4 and CD8 T cells are required for diabetes to occur (( 1 ), ( 2 )), both CD8 T cells (( 11 )) and CD4 T cells (( 12 )) are able to transfer disease when given alone to NOD.SCID animals, which lack lymphocytes. (rupress.org)
  • vitro
  • The present study was conducted to determine whether the stress of physical work further affects the expression of splenic lymphocyte phenotypes following in vitro stimulation by the T-cell mitogen, Con A, and also by interleukin-1 (IL1). (biomedsearch.com)
  • cells
  • To elucidate the relative importance of each of the subsets of cells, the NOD-rat insulin promoter (RIP)-B7-1 animals were crossed with NOD.β2microglobulin −/− mice which lack major histocompatibility complex class I molecules and are deficient in peripheral CD8 T cells, NOD.CD4 −/− mice which lack T cells expressing CD4, and NOD.μMT −/− mice which lack B220-positive B cells. (rupress.org)
  • There was a significantly greater increase in the percentage of Thy1.2+ and, especially of, Lyt-2+ cells in stimulated splenic lymphocytes from untrained mice given an exhaustive exercise session compared with controls and with trained mice. (biomedsearch.com)
  • The lack of B-lymphocytes in the testis is significant, since these are the antibody-producing cells of the immune system. (wikipedia.org)
  • T-lymphocytes (T-cells) are white blood cells which take part in cell-mediated immunity. (wikipedia.org)
  • significant
  • There was a significant effect of stimulation by Con A on the percentage of splenic lymphocytes positive for Thy1.2, Lyt-2, L3T4, and goat anti-mouse Ig, regardless of treatment condition. (biomedsearch.com)