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  • Cell Biology
  • One of the first numerical simulations in cell biology was published in 1952 by the British neurophysiologists and Nobel prize winners Alan Lloyd Hodgkin and Andrew Fielding Huxley , who constructed a mathematical model that explained the action potential propagating along the axon of a neuronal cell. (wikipedia.org)
  • An independent review of 2017 ranked SBI as one of the top four research centres that integrate computational modelling with experimental cell biology. (ucd.ie)
  • The postholder should have knowledge of molecular and cell biology. (ucd.ie)
  • The appointee should have a broad repertoire of technical skills and methods used for the analysis of signal transduction networks, including cell biology, protein biochemistry, and standard molecular biology. (ucd.ie)
  • The student will gain valuable knowledge in the analysis of signal transduction networks in colon cancer, protein analysis techniques, and standard methods used in molecular and cell biology. (ucd.ie)
  • The CSBD was started in 2010 by the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) and the Max Planck Institute for the Physics of Complex Systems (MPI-PKS) with the generous support of the Saxon State Ministry for Higher Education, Research and the Arts, the BMBF, and the Klaus Tschira Stiftung. (mpi-cbg.de)
  • biomedicine
  • The goal of this course is to introduce the core concepts of systems biology and their application to systems biomedicine. (systemsbiology.org)
  • This course is aimed at graduate students, post-doctoral fellows and principal investigators with an interest in systems biomedicine. (systemsbiology.org)
  • The course will introduce systems biomedicine which is the application of a systems view to disease with the goal of developing multi-scale models that provide better classification, biomarkers and drug target. (systemsbiology.org)
  • This course is designed as an introduction to systems biomedicine with lectures, hands on interactive sessions using the statistical programming language R, and panel discussions. (systemsbiology.org)
  • The course is aimed at graduate students, postdoctoral fellows, biomedical researchers, educators and principal investigators with an interest in systems biomedicine. (systemsbiology.org)
  • A volume book entitled 'Understanding and Exploiting Systems Biology in Bioprocesses and Biomedicine' will be published including Full papers of works (oral, posters) presented at the conference. (um.es)
  • Mathematics
  • This course focuses on intensive study of the primary literature to learn from published examples of systems biology and the application of mathematics in biology. (abdn.ac.uk)
  • These chapters target topics and solutions in computer science, mathematics, physics, biology, and the pharmaceutical and biomedical areas. (wiley-vch.de)
  • Understanding
  • Systems biology is defined for the purpose of this study as the understanding of biological network behaviors, and in particular their dynamic aspects, which requires the utilization of mathematical modeling tightly linked to experiment. (springer.com)
  • Crop systems biology analyses and models complex phenotypic traits expressed at crop level - the hierarchical level relevant to real-life agricultural production - by using information from "omics", underlying biochemical and molecular-physiological understanding and linking that information in a coherent and scale logical way to yield determining, crop physiological component processes. (wur.nl)
  • A key aspect is the combination of information from multiple levels - genes, proteins, whole cells, natural forces - to gain a clear understanding of the specific inputs and processes that lead to specific system behaviors. (systemsbiology.org)
  • Understanding how the behavior of biological systems is altered based on changes to their underlying networks is a crucial part of understanding how diseases arise and can be cured or how ecosystems fail and can be rebuilt. (systemsbiology.org)
  • Searching for organizing principle: Understanding in systems biology. (springer.com)
  • Consequently understanding proteins and their function is a key part of biology. (ucd.ie)
  • Researchers
  • Systems Biology Ireland is a vibrant and diverse international community of researchers working across systems biology and related disciplines. (ucd.ie)
  • Seamless integration and in-depth analysis of rich systems data are made possible by a flexible and extensible environment called Gaggle, a framework that extends the reach of individual researchers. (systemsbiology.org)
  • chemistry
  • The course is mostly appropriate for beginning graduate students and advanced undergraduates majoring in fields such as biology, math, physics, chemistry, computer science, biomedical and electrical engineering. (coursera.org)
  • Applicants should have, or expect to obtain, a first or upper second class honours Bachelors or Masters degree in Biology, Biochemistry, Systems Biology, Chemistry or related fields. (ucd.ie)
  • aims
  • By doing so crop systems biology aims to assist in orchestrating the knowledge chain from molecule and gene through cell and tissue or organ all the way up to plant and plant community in order to predict crop phenotype and crop performance. (wur.nl)
  • Driven by technology, MaCSBio aims to understand and predict the complex nature of biological systems. (maastrichtuniversity.nl)
  • processes
  • The various disciplines involved in systems biology investigate the principles underlying system behaviors and spatiotemporal processes such as the question of how tens of thousands of cells coordinate their behavior in space and time to form tissues of a given form and function. (mpi-cbg.de)
  • Cells
  • Such analysis can be conducted at any scale of biological organization, ranging from single cells to ecological systems. (frontiersin.org)
  • A key notion within SB&E is that biological systems are described by 'networks' of components (like genes, enzymes, cells, and even species or agents). (wur.nl)
  • The project will investigate how signalling and protein interaction networks are context-specific quantitatively modulated in (patho)physiologically-relevant primary cells and in vivo-like 3D model systems. (ucd.ie)
  • The cells in the immune system, in particular T cells, must be ready to respond quickly to antigens in order to organize a rapid response to pathogens. (upf.edu)
  • When the system goes awry, the body runs the risk of responding too weakly to external insults (immunodeficiency) or, in the other extreme, to respond too much and attack its own cells (autoimmunity). (upf.edu)
  • In order to face these disorders, we need to understand how the immune system cells respond to their external triggers. (upf.edu)
  • The Baliga group develops models of biological systems, from single cells to communities of multiple organisms, that accurately predict adaptation to environmental changes. (systemsbiology.org)
  • Depending on the size of the system, these parts can be genes, proteins, whole cells or even whole populations. (systemsbiology.org)
  • Medicine
  • Kolch has designed, developed and coordinated innovative systems biology, systems medicine and precision medicine programmes of vision, scale and impact throughout his career, with a track record of competitive grant funding of over €200M. (ucd.ie)
  • The text concludes with examples of how the systems information is used to inform personalized medicine in a true "bench to bedside" manner. (springer.com)
  • As part of ISB's mission of systems biology and P4 medicine we are pleased to offer training in all services and hands-on access to all facility instruments to qualified individuals. (systemsbiology.org)
  • Department of Pharmacology and Systems Therapeutics and the Systems Biology Center New York, Mount Sinai School of Medicine, New York, NY 10029, USA. (sciencemag.org)