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  • fever
  • Although the disease can affect different organs, systemic symptoms such as fever, night sweats, and weight loss are common. (visualdx.com)
  • certain patterns of fever suggest multisystem disease. (pmmonline.org)
  • Persistent fever (more than 7 days) and with quotidian pattern (i.e., high in the evenings) suggests systemic JIA to be more likely. (pmmonline.org)
  • inflammation
  • Cryoglobulinemia is characterized by the presence of cryoglobulins in the serum, forming cryoglobulin-containing immune complexes, which may result in a clinical syndrome of systemic inflammation, most commonly affecting the kidneys and skin. (ning.com)
  • Therapeutic agents that block IL-1 eliminate most systemic inflammation and may decrease long term complications. (clinicaladvisor.com)
  • induction
  • The intent is to reduce the toxicity of induction therapy by reducing the overall exposure to or eliminating entirely the use of systemic corticosteroids during the induction period with an inhibitor of the complement C5a receptor plus cyclophosphamide or rituximab. (clinicaltrials.gov)