• In the training set, 13 DNA repair genes were screened using univariate proportional hazard (Cox) regression analysis and least absolute shrinkage and selection operator (LASSO) Cox regression analysis to construct a risk model, which was validated in the testing set. (frontiersin.org)
  • Data from the TCGA-BRCA cohort were analyzed using univariate Cox regression analysis, and least absolute shrinkage and selection operator (LASSO) analysis was performed to build a stable prognostic model. (aging-us.com)
  • In multivariate regression analysis, thicker subfoveal choroid and thinner central retina were significantly associated with higher CVI values. (scite.ai)
  • Candidate prognostic factors for OS with 0.05 significance level in univariate analysis were included in a multivariate Cox model. (biomedcentral.com)
  • One of the six key recommendations is that physicians should systematically use prognostic scores to stratify patients into groups with different survival times. (biomedcentral.com)
  • Summary: This study systematically investigated the prognostic implications of the components of the PDAC tumor microenvironment by integrating single-cell sequencing and bulk sequencing, and long term studies are expected to develop novel targeted providers for PDAC treatment. (biotech2012.org)
  • While hyperpolarized (HP) gas MRI has been used to estimate alveolar oxygen tension ( p A O 2 ) [1], it has not been systematically compared to Gold standard to assess its potential for monitoring disease progression and response to new therapies. (gitlab.io)
  • The primary aim of our review is to therefore systematically assess the existing research to increase our understanding of factors that have the potential to be strengthened or changed to reduce the likelihood of depression onset among maltreated children. (nature.com)
  • By using multivariate analyses to assess neural activity patterns in response to the different stimulus types, we reveal a stimulus category and modality specific brain organization of affective signals. (frontiersin.org)
  • Multivariate analyses were used to assess the relationship between high globulin fraction and healthcare utilization. (annalsgastro.gr)
  • In the current study, we tested whether using individual ROIs leads to changes in decodability of task-related neural representations as well as univariate activity across the MD network compared with when using a group template. (mit.edu)
  • We investigated the neural computations which might support this feat, using the macaque superior temporal sulcus (STS) as a model system. (jneurosci.org)
  • Previous neuroimaging studies using classical univariate analyses have tied such emotion dysregulation to aberrant activity levels in the amygdala of patients with BPD. (bvsalud.org)
  • With an abundant amount of resources in the publicly available database, such as the Cancer Genome Atlas (TCGA) database, an integrative strategy is used to systematically characterize the aberrant patterns of colorectal cancer (CRC) based on RNA-Seq, chromatin immunoprecipitation sequencing (ChIP-Seq), tissue microarray (TMA), gene profiling and molecular signatures. (oncotarget.com)
  • METHODS: We systematically searched 5 databases for articles published before October 6, 2021, that modeled health or economic effects of IIV4 versus IIV3. (cdc.gov)
  • Methods Circulating (n = 179) and hepatic expression (n = 95) of ghrelin and LEAP-2 were measured in patients with severe obesity and available liver pathology analysis undergoing Roux-en-Y gastric bypass (RYGB). (unav.edu)
  • Image_5.jpg (1.8M) GUID:?DD754633-4A29-4499-AAC3-81AACC2A8B47 Supplementary Table 1: The uncooked data and univariate COX analysis for the 119 cell signatures and PDACs' survival in 7 cohorts. (biotech2012.org)
  • The potential participation of ghrelin and the ghrelin receptor antagonist, LEAP-2, in the onset of liver fibrosis in patients with severe obesity and NAFLD through the regulation of TGF-& beta;1-induced hepatic stellate cell (HSC) activation was investigated. (unav.edu)
  • We investigated the relationship between maternal anaemia and perinatal outcome in a cohort of 629 pregnant women from October 2001 to 2002. (who.int)
  • We investigated the 12-months prognosis of CRTd patients with diabetes, previously treated with hypoglycemic drugs therapy (n 271) vs. a matched cohort of CRTd patients with diabetes treated with GLP-1 RA in addition to conventional hypoglycemic therapy (n 288). (biomedcentral.com)
  • We then systematically assessed univariate and multivariate results in a separate rule-based criterion task. (mit.edu)
  • Consistent with previous studies, we found a clear benefit of the subject-specific ROIs for univariate results from the criterion task, with increased activity in the individual ROIs based on the localizers' data, compared with the activity observed when using the group template. (mit.edu)
  • In contrast, there was no benefit of the subject-specific ROIs for the multivariate results in the form of increased discriminability, as well as no cost of reduced discriminability. (mit.edu)
  • Both univariate and multivariate results were similar in the subject-specific ROIs defined by each of the three localizers. (mit.edu)
  • Our results provide important empirical evidence for researchers in the field of cognitive control for the use of individual ROIs in the frontoparietal network for both univariate and multivariate analysis of fMRI data and serve as another step toward standardization and increased comparability across studies. (mit.edu)
  • The purpose of this study was to investigate the relationship between student-athletes and non-athletes on emotional intelligence (EI), and whether or not the involvement in collegiate sports moderates the relationship between EI and academic achievement as measured by the grade point average (GPA). (thesportjournal.org)
  • Conclusions: This study systematically investigated periodontitis immune atlas and glimpse the underlying mechanism of periodontitis from gene-pathway-immunocyte networks, which can not only inspire researchers but also help them in periodontitis related immune researches. (researchsquare.com)
  • Anecdotal reports suggest a prominent role for kinesiophobia in disease manifestations, but no study has systematically addressed this point. (hindawi.com)
  • As the vitamin D status of Algerian postmenopausal women was poorly described, this cross-sectional study investigated the prevalence of low vitamin D status in a sample population. (hindawi.com)
  • To our knowledge, no study has ever investigated these parameters in the country to date. (biomedcentral.com)
  • The White House asked the Department of Health and Human Services to investigate the issues raised by the study. (cdc.gov)
  • This proposed multivariate timing mixture model can be viewed as a generalization of the univariate exponential-gamma model. (scite.ai)
  • We investigate this problem through a mixture of research questions and by studying individuals, families and populations. (brookes.ac.uk)
  • Background and Objective Borderline Personality Disorder (BPD) is under-investigated in First Episode Psychosis (FEP). (bvsalud.org)
  • While there is a growing literature on investigating the Internet clickstream data collected for a single site, such datasets are inherently incomplete because they generally do not capture shopping behavior across multiple websites. (scite.ai)
  • The final multivariate model was constructed through backward selection among predictors that were found statistically significant (p (acrabstracts.org)
  • We also aimed to investigate a third model including additional clinical and biological characteristics and thus potentially allowing for more accurate prognostication. (biomedcentral.com)
  • In a multivariate logistic regression model adjusted for the frequency of sexual intercourse, not having had access to prevention interventions and not knowing any HIV-infected person were both independently associated with a higher risk of UAI. (bmj.com)
  • This result remained significant after multivariate analysis for both Crohn's disease patients and those with ulcerative colitis. (annalsgastro.gr)
  • The Department, in turn, referred this request to the Agency for Toxic Substances and Disease Registry (ATSDR), which was already investigating environmental public health issues in Vieques. (cdc.gov)
  • To investigate the impact of kinesiophobia and its relationship with pain, fatigue, and quality of life in JHS/EDS-HT. (hindawi.com)
  • Confounders such as socioeconomic status, parental occupation, and health-related behaviors should be explored further to investigate the relationship between breastfeeding and OSAS. (biomedcentral.com)
  • We identified three studies investigating accessibility of the location of the antiseptic hand rub dispenser. (biomedcentral.com)
  • In addition, due to the number of subjects evaluated in majority of these studies was small and the majority of these studies had relatively narrow age ranges, they failed to systematically assessed a wide range of risk factors that was associated with risk of OSAS. (biomedcentral.com)
  • My work broadly investigates the drivers of population health improvements in developing countries. (stanford.edu)
  • Despite evidence indicating widespread application of CCM to multiple illnesses, such as diabetes, congestive heart failure, and asthma (6), no summative reviews have investigated how CCM has been applied in diabetes care. (cdc.gov)
  • Patients with RA have a longer LOS after THA/TKA than OA patients, yet the factors contributing to LOS, including preoperative opioid use, have not been investigated. (acrabstracts.org)
  • If these benefits are confirmed, this exercise intervention could be systematically proposed to patients during the course of treatment by trastuzumab in addition to standard oncological care. (biomedcentral.com)
  • Background: Immunity and immunocyte reaction play an essential role in periodontitis progress and we aim to investigate the underlying regulatory network of periodontitis immune alterations. (researchsquare.com)
  • Working closely with other collaborators active in this field, we aim to identify specific genetic variants that cause this predisposition and to investigate the kinds of biological processes that they take part in. (brookes.ac.uk)
  • This review aims to systematically examine the existing literature to identify modifiable factors that increase vulnerability to, or act as a buffer against, depression, and could therefore inform the development of targeted interventions. (nature.com)
  • To investigate the risks of the sudden infant death syndrome and factors that may contribute to unsafe sleeping environments. (bmj.com)
  • Table_2.XLSX (555K) GUID:?46F26156-6A42-4A75-A7CA-EEA98625028C Supplementary Table 3: Multivariate cox regression validates the association between OS and cytotoxic T cell signatures in targets_high group is definitely independent of additional infiltrated cell components. (biotech2012.org)
  • If instead the inefficiency is found in the stock market, it would imply that financial resources are not being attracted appropriately to their most productive uses, and that abnormally high rates of return are systematically possible in the stock market. (lu.se)
  • One of the most investigated issues in financial economics is whether the variation in stock prices or returns is predictable. (lu.se)
  • A common practice of applying MVPA is by investigating pattern discriminability within a ROI using a template mask, thus ensuring that the same brain areas are studied in all participants. (mit.edu)