• Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's disease) weakens and eventually destroys the body's motor neurons, making functions such as walking and talking very difficult. (pva.org)
  • An observational study to assess clinical manifestations and biomarkers in amyotrophic lateral sclerosis type 4 and other inherited neurological disorders of RNA processing. (nih.gov)
  • Syringomyelia is a condition characterized by a fluid-filled cavity or cyst known as a syrinx that forms within the spinal cord. (rarediseases.org)
  • Syringomyelia is a chronic condition and a syrinx can expand over time compressing or destroying the surrounding nerve tissue. (rarediseases.org)
  • A wide variety of symptoms can potentially be associated with syringomyelia depending upon the size and exact location of the syrinx. (rarediseases.org)
  • The aim of this study was to evaluate the microstructure of the cervical cord in patients with syringomyelia using diffusion tensor imaging (DTI) and to investigate the association between DTI parameters and the size of the syrinx cavity. (nih.gov)
  • It is often referred to as a variant of syringomyelia, which is a similar condition in which a syrinx forms within the spinal cord itself. (articleinsider.com)
  • Syringomyelia: Formation of cyst within the spinal cord (syrinx) that can expand and destroy the spinal cord. (neurocare.ai)
  • The majority of cases of syringomyelia are associated with a complex brain abnormality known as a Chiari malformation. (rarediseases.org)
  • Syringomyelia is often associated with an abnormality of the craniovertebral junction, usually a Chiari malformation (types I and II), and these cases may be referred to as congenital syringomyelia. (rarediseases.org)
  • Multiple sclerosis (MS) is a chronic autoimmune condition affecting the CNS. (medscape.com)
  • Syringomyelia (SM) is a chronic spinal cord disorder that forms before birth or as a result of an accident, tumor or disease. (pva.org)
  • The term "multiple sclerosis" refers to the many areas of scarring (sclerosis) that result from destruction of the tissues that wrap around nerves (myelin sheath) in the brain and spinal cord. (msdmanuals.com)
  • Immobile tongue is present in bilateral lingual paralysis, bulbar palsy, advanced malignancy of tongue, and syringomyelia. (mktalks.com)
  • Significant, reproducible fatigue of motor function with substantial muscle weakness on repetitive activity, demonstrated on physical examination, resulting from neurological dysfunction in areas of the central nervous system known to be pathologically involved by the multiple sclerosis process. (youngmarrlaw.com)
  • Multiple Sclerosis (MS) is a disease of the central nervous system and the most common neurological disorder in young adults. (pva.org)
  • For patients in whom syringomyelia is suggested by clinical criteria, the diagnosis should be confirmed by radiographic investigation. (medscape.com)
  • 17. A challenging diagnosis of late-onset tumefactive multiple sclerosis associated to cervicodorsal syringomyelia: doubtful CT, MRI, and bioptic findings: Case report and literature review. (nih.gov)
  • Alternatively, an accumulation of CSF may dissect into the surrounding white matter to form a paracentral cavity, in which case none of the cavity is lined by ependyma (ie, syringomyelia ). (medscape.com)