• Among discordant sera, the rate of nonreactive confirmatory treponemal tests was 2.9 times higher in a population with low prevalence of syphilis, suggesting that the low-prevalence population had a higher percentage of false-positive test results. (cdc.gov)
  • The purpose of this study was to determine the prevalence of syphilis among blood donors and whether seroconversion occurred in transfusion recipients. (cdc.gov)
  • The high prevalence of syphilis seropositivity in blood donors and seroconversion of a transfusion recipient shows that in centers where screening is not conducted, recipients of blood transfusions are at risk for contracting transfusion-transmitted syphilis. (cdc.gov)
  • Methods for surveillance and monitoring of congenital syphilis elimination within existing systems. (who.int)
  • Routine screening of blood donors and refrigeration of donated blood before its use has resulted in only 3 reported cases of transfusion-transmitted syphilis over the past 4 decades ( 2 - 6 ). (cdc.gov)
  • As a result, serologic testing is the method most often used to diagnose syphilis in patients with suspected disease. (cdc.gov)
  • Serologic tests for syphilis. (bvsalud.org)
  • Transfusion-transmitted syphilis, which is caused by Treponema pallidum subspecies pallidum , is one of the oldest recognized infectious risks of blood transfusion ( 1 ). (cdc.gov)
  • Pretransfusion plasma samples from 200 conscious transfusion recipients in adult, pediatric, and obstetric inpatient departments and samples of their transfused blood were tested for syphilis. (cdc.gov)
  • This recipient who showed seroconversion most likely had a case of transfusion-transmitted syphilis. (cdc.gov)
  • Such short periods of blood storage do not provide an adequate margin of safety against transfusion-transmitted syphilis. (cdc.gov)
  • Findings from this study have been discussed with the hospital transfusion committee, and new syphilis screening guidelines and testing algorithms are being developed. (cdc.gov)
  • Treponema pallidum , the bacterium that causes syphilis, cannot be cultured. (cdc.gov)
  • Sixteen units (8%, 95% confidence interval [CI] 4.3%-11.7%) were seropositive for syphilis by EIA and TPHA. (cdc.gov)
  • The World Health Organization recommends screening all donated blood for syphilis ( 7 ), but doing so is challenging for many developing countries. (cdc.gov)
  • Development and evaluation of modern enzyme immunoassays for comprehensive syphilis serology = Ontwikkeling en evaluatie van moderne enzym immunoassays voor toepassing in de verschillende aspecten van syfilisserologie / door Otto Emmanuel Ijsselmuiden. (who.int)
  • Discordant testing results could be caused by 1) previous syphilis infection, treated or untreated, with persistence of treponemal antibodies but seroreversion of nontreponemal antibodies, 2) a false-positive treponemal test result, or 3) early primary syphilis in a person who has yet to develop nontreponemal antibodies. (cdc.gov)
  • evaluation and application of sexually transmitted infection diagnostic tests including syphilis screening appropriate for use in primary health care settings in developing countries.Objective: To evaluate the performance of SD BIOLINE Syphilis 3.0 test (Standard Diagnostics Inc. (bvsalud.org)
  • Serodiagnosis of syphilis involves the detection of two distinct types of antibodies: 1) nontreponemal antibodies directed against lipoidal antigens released from damaged host cells and possibly from the treponemes themselves and 2) treponemal antibodies directed against T. pallidum proteins. (cdc.gov)
  • 94) compared to RPR test.Conclusion: The overall sensitivity (79) of SD BIOLINE syphilis 3.0 test found is low whereas specificity (96) found is similar compared to the previous evaluation but higher compared to the sensitivity (68) and specificity (94) of the currently used RPR test. (bvsalud.org)
  • Utilisation des tests diagnostiques rapides de la syphilis. (who.int)
  • Although CDC continues to recommend the traditional algorithm with reactive nontreponemal tests confirmed by treponemal testing, in this report CDC offers additional recommendations if reverse sequence syphilis screening is used. (cdc.gov)
  • 8.2(41/498) on SD BIOLINE Syphilis 3.0 and 9.8(49/498) on RPR tests. (bvsalud.org)
  • Page 1 of 5 - EN 3800-29 Rev H Captia™ HSV 1 Type Specific IgG 2323800 96 Tests 2323801 480 Tests negative range of the assay. (fliphtml5.com)
  • Since the 2008 CDC report, confusion has persisted among clinicians, laboratorians, and public health practitioners regarding testing and treatment decisions and partner notification when using the reverse sequence for syphilis screening ( 3 ). (cdc.gov)
  • She was referred to pediatricians for treatment of syphilis. (cdc.gov)
  • Development and evaluation of modern enzyme immunoassays for comprehensive syphilis serology = Ontwikkeling en evaluatie van moderne enzym immunoassays voor toepassing in de verschillende aspecten van syfilisserologie / door Otto Emmanuel Ijsselmuiden. (who.int)
  • Ontwikkeling en evaluatie van moderne enzym immunoassays voor toepassing in de verschillende aspecten van syfilisserologie. (who.int)
  • Méthodes pour la surveillance et le suivi de l'élimination de la syphilis congénitale dans le cadre des systèmes existants. (who.int)
  • The film also shows the promotional literature using the phrase 'bad blood' as a substitute for syphilis: flyers posted near gathering places and flyers used as wrappers for purchases, for example. (nih.gov)