• The most important functional materials in this category include proton exchange membranes and alkaline anion exchange membranes, that are at the heart of many technologies in water treatment, energy storage, energy generation. (wikipedia.org)
  • Our main research area comprises new generations of ionic polymers for proton- and anion-exchange membranes for energy conversion and storage systems such as fuel cells, water electrolyzers and flow batteries. (lu.se)
  • Synthetic oligomers - tiny complexes that consist of a few selected molecules bound together - can be structurally engineered to exhibit certain behavior and have proven to be promising antimicrobial candidates. (nanowerk.com)
  • Here, we describe the concept of augmented synthetic lethality (ASL): depletion of a third gene product enhances a pre-existing synthetic lethal combination. (nature.com)
  • The resulting duplication of the lnp1(+) gene, which encodes an endoplasmic reticulum membrane protein, suppressed lem2∆ phenotypes, whereas the lem2∆ lnp1∆ double mutant showed a severe growth defect. (nih.gov)
  • I am a plant cell biologist and protein biochemist at Oxford Brookes University with expertise in the structure and function of the plant endoplasmic reticulum (ER), membrane proteins and auxin biosynthesis using biochemical techniques as well as high-resolution live cell imaging. (brookes.ac.uk)
  • We are interested in a range of applicants to help us develop technologies associated with materials science (for developing membrane technologies to create protocells), engineers and physicists (interested in studying developing platforms for protocell synthesis and-or diagnostics), and chemists (for new reagents to use with synthetic biology). (gla.ac.uk)
  • In biology, cells use a variety of mechanisms to deal with sudden changes in their surroundings. (sciencedaily.com)
  • From the vantage point of developing predictive design and formation approaches for synthetic materials, the observations suggest how chemical energy stored across adjacent regions with unequal distributions of dissolved molecules can use processes derived from biology to drive structural reorganizations for advanced functions. (sciencedaily.com)
  • Cancer research at UC Santa Cruz includes faculty in a wide range of departments, including Applied Math and Statistics, Biomolecular Engineering, Chemistry and Biochemistry, Electrical Engineering, Microbiology and Environmental Toxicology, and Molecular, Cell, and Developmental Biology. (ucsc.edu)
  • The mechanisms by which cells control their growth and size are poorly understood and represent a fundamental unsolved problem in cell biology. (ucsc.edu)
  • In this project I will develop the first mechanically-adaptable nanopores for size-selective biomolecule transport across cell membrane by uniquely combining DNA origami nanotechnology, machine-inspired design and synthetic biology. (tudelft.nl)
  • Many polymers are available, but the choice of membrane polymer is not a trivial task. (wikipedia.org)
  • The polymer has to be a suitable membrane former in terms of its chains rigidity, chain interactions, stereoregularity, and polarity of its functional groups. (wikipedia.org)
  • The polymer has to be obtainable and reasonably priced to comply with the low cost criteria of membrane separation process. (wikipedia.org)
  • Polysulfone (PS) Polyethylene (PE) Polytetrafluoroethylene (PTFE) Polypropylene (PP) Polymer membranes may be functionalized into ion-exchange membranes by the addition of highly acidic or basic functional groups, e.g. sulfonic acid and quaternary ammonium, enabling the membrane to form water channels and selectively transport cations or anions, respectively. (wikipedia.org)
  • Many molecular components involved in plant cell wall polymer synthesis have been identified, but it remains largely unknown how these molecular players function together to define the length and decoration pattern of a polysaccharide. (mdpi.com)
  • Ceramic membranes are produced from inorganic materials such as aluminium oxides, silicon carbide, and zirconium oxide. (wikipedia.org)
  • Ceramic membranes are very resistant to the action of aggressive media (acids, strong solvents). (wikipedia.org)
  • Even though ceramic membranes have a high weight and substantial production costs, they are ecologically friendly and have long working life. (wikipedia.org)
  • Ceramic membranes are generally made as monolithic shapes of tubular capillaries. (wikipedia.org)
  • Since high pressure enhances the total process efficiency, membrane reactor consists of tubular ceramic membranes able to withstand very high outside gas pressure. (europa.eu)
  • Lipids were likely one of the first components necessary for life, yet our understanding of how lipid membranes could have arisen spontaneously is a mystery. (rutgers.edu)
  • Our ultimate goal is to answer fundamental questions about the origins of lipid membranes and build a functional understanding of the diverse array of lipids present in life today. (rutgers.edu)
  • Antimicrobial peptides selectively attack bacterial cell membranes. (sc.edu)
  • First-generation semisynthetic cephalosporin that arrests bacterial cell wall synthesis, inhibiting bacterial growth. (medscape.com)
  • Binds to one or more penicillin-binding proteins, which, in turn, inhibits synthesis of bacterial cell walls. (medscape.com)
  • It has a unique structure with one 'tail' at each end of the chain, and they found that, once the bacterium is 'caught', these tails act like drills that penetrate and destroy the bacterial cell membranes. (nanowerk.com)
  • Their achievement, detailed in a paper published in this week's issue of the Proceedings of the National Academy of Sciences, will allow scientists to more accurately replicate the behavior of living cell membranes, which until now have been modeled only by synthetic cell membranes without the ability to add new phospholipids. (blogspot.com)
  • Most of the cell membrane is formed by phospholipids that have a unique structure that causes them to self-arrange into a double layer that is hydrophobic in the middle and hydrophilic on the outside. (visionlearning.com)
  • Membranes are usually made of layers of phospholipids containing suspended protein molecules and are permeable to water and fat-soluble substances. (dictionary.com)
  • Inhibition of this system impairs the synthesis of ergosterol, a vital component of fungal cell membranes. (medscape.com)
  • It slows fungal cell growth by inhibiting cytochrome P-450-dependent synthesis of ergosterol, a vital component of fungal cell membranes. (medscape.com)
  • In vitro membrane-bound vesicles obtained by 'bisecting' (although the two parts were not always identical in size) an in vitro contractile vacuole established their own independent rounding-slackening cycles. (biologists.com)
  • Severed radial arms also became vesiculated and, like contractile vacuole membranes, these in vitro vesicles showed independent rounding-slackening cycles and vesicle-vesicle fusions. (biologists.com)
  • A ROR1-targeting scFv with a membrane-proximal epitope, R11, revealed potent and selective antitumor activity in vitro and in vivo and emerged as a prime candidate for further preclinical and clinical studies. (biorxiv.org)
  • Here, we review the structural elements required for designing mRNA vaccine constructs for effective in vitro synthetic transcription reactions. (mdpi.com)
  • Activity lasted for over 30 min at room temperature (24-27 degrees C). The rounding of the in vitro contractile vacuole corresponded to the increased membrane tension of the in vivo contractile vacuole that occurs immediately before fluid expulsion. (biologists.com)
  • The subsequent slackening of the in vitro contractile vacuole corresponded to the fluid-filling phase of the in vivo contractile vacuole that occurs at decreased membrane tension. (biologists.com)
  • An additional rounding phase of the in vitro contractile vacuole could be induced by applying suction to a portion of its membrane with a micropipette when the contractile vacuole was in its slackened phase. (biologists.com)
  • We now understand that the plasma membrane is a very dynamic part of the cell and that is much more than just a barrier. (visionlearning.com)
  • However, a key challenge in translating siRNA into the clinic is the inefficacy to deliver siRNA across the plasma membrane, but most importantly, to escape the endosomal system and reach the cytosol where they can interact with the RNA interference machinery. (lu.se)
  • Among these MDR pathogens, Gram-positive bacteria, which have only a single cell membrane, have received most of the attention from researchers. (sc.edu)
  • The dual membranes found in Gram-negative bacteria act as an impermeable barrier to many antibiotics. (sc.edu)
  • To address these challenges, previous research has successfully used synthetic polymers, which mimic natural antimicrobial peptides produced by bacteria to kill other bacteria. (sc.edu)
  • An interdisciplinary group of researchers at UofSC has already developed several antimicrobial macromolecules that successfully combat bacteria, particularly Gram-positive bacteria such as methicillin-resistant Staphylococcus aureus (MRSA), with low toxicity effects on human cells. (sc.edu)
  • The molecules are unique because they change shape, snaking their way into bacterial membrane defenses and splitting the cells open, killing the bacteria. (sc.edu)
  • This causes destabilization and fragmentation, ultimately leading to bacteria cell death. (sc.edu)
  • The researchers found these new polymers to be highly-effective against MDR Gram-negative bacteria, despite their double membranes. (sc.edu)
  • Finally, we are interested in developing fuel cells based upon engineering bacteria that can participate in electron transfer - in effect using biological fuels (such as sugars) to power devices. (gla.ac.uk)
  • Now, A*STAR researchers have developed a synthetic molecule capable of killing bacteria such as E.coli in seconds, far more rapidly than any antimicrobial product, such as hand wash or surface spray, currently on the market ( Small , 'Ultrafast killing and self-gelling antimicrobial imidazolium oligomers' ). (nanowerk.com)
  • A*STAR researchers have developed a synthetic molecular complex capable of destroying common bacteria in seconds. (nanowerk.com)
  • The team created the material using positively-charged molecules linked together in a chain to attract negatively-charged bacteria cells. (nanowerk.com)
  • Once the cell membranes are ruptured, the bacteria die instantly. (nanowerk.com)
  • Traveling through the bodily fluids of an infected person, Ebola enters through a mucous membrane or break in the skin. (dictionary.com)
  • Small fragments of mucous membrane may be found, and when examined by a pathologist, may occasionally establish the diagnosis. (dictionary.com)
  • The damage which they do to the mucous membrane favors bacterial invasion. (dictionary.com)
  • It lives in the large intestine, especially the cecum, with its slender extremity embedded in the mucous membrane . (dictionary.com)
  • A group of autoimmune blistering diseases affecting primarily the mucous membranes is termed mucous membrane pemphigoid (MMP) (also termed cicatricial pemphigoid ). (medscape.com)
  • The polymers can range form amorphous and semicrystalline structures (can also have different glass transition temperatures), affecting the membrane performance characteristics. (wikipedia.org)
  • Many membrane polymers are grafted, custom-modified, or produced as copolymers to improve their properties. (wikipedia.org)
  • Now an elegant method of counting the oligomers in membrane proteins in near-native states is presented, using photobleaching and nanodiscs formed directly from cellular membranes. (nature.com)
  • The thread was lodged in the perforated part, and consequently left in contact with the cellular membrane . (dictionary.com)
  • Hinck's lab has identified a family of cellular proteins that help regulate cell proliferation and migration and act as breast tumor suppressors. (ucsc.edu)
  • Delivering beneficial macromolecules across the cellular membrane is a significant challenge since these molecules are too large to shuttle into cells through the nanochannels. (tudelft.nl)
  • While the biological process is reasonably well understood, translating this resiliency into synthetic materials remains a major challenge. (sciencedaily.com)
  • Mar. 16, 2022 Biological processes such as wound healing and cancer cell invasion rely on the collective and coordinated motion of living cells. (sciencedaily.com)
  • Although the architecture of the nanomachines is known, a detailed understanding of how the splitting of the energy carrier ATP dynamically enables the transport of various substances across biological membranes has so far been lacking. (nanowerk.com)
  • Zombie" biological cell membranes attract pharmacologically active compounds that could eventually be used in far-reaching, advanced medications. (syfy.com)
  • Construction of synthetic nanopores for the transport of large biological cargoes would be a step forward. (tudelft.nl)
  • and (iii) to use the thus generated knowledge to unravel generic features of the dynamics of macromolecules and particles of biological origin in dense solutions such as those found in the interior of living cells. (lu.se)
  • The project combines several parallel research efforts connecting systems of synthetic and biological origin to highlight features of general applicability, and is also based on an extensive international collaboration involving several key research groups. (lu.se)
  • For instance, when the level of dissolved nutrient molecules (e.g., sugar) in the cell's watery environment drops, water flows into the cell through osmosis. (sciencedaily.com)
  • Protein channels in the cell's membrane release the excess water, preventing catastrophic expansion and bursting of the cell. (sciencedaily.com)
  • Using ionic solvents, Ciesla and his team leeched out the cell's innards before using its membrane as a casing for iron oxide. (syfy.com)
  • These dental stem cells are considered mesenchymal stem cells (MSCs) and possess different levels of capacities to become specific tissue forming cells. (bvsalud.org)
  • The combination of such self-organizational phenomena with canonical intermolecular interactions is most likely to control the release of membrane proteins from the ER into the secretory pathway. (biologists.com)
  • This process depends on the general physico-chemical features of the cargo membrane protein and on the interactions of these features with the collective properties of the bilayer, instead of the one-to-one intermolecular interactions that exist between discrete signals and their receptors. (biologists.com)
  • These genetic interactions imply that Lem2 cooperates with the nuclear membrane protein network to regulate genome stability. (nih.gov)
  • I am committed to interdisciplinary research, and an example of the successes gained from this approach is the project with Prof A Nabok (Engineering Sheffield Hallam University) using total internal reflection ellipsometry to quantify protein-membrane interactions on native plant membranes and human cell lines. (brookes.ac.uk)
  • Program access grant to the STFC Harwell Laser Facility 'The Plant Cell Initiative: Protein interactions in the higher plant secretory pathway' 2017-2021 (approximate value of £200K). (brookes.ac.uk)
  • We show that loss of the DNA repair protein XPA markedly augments the synthetic lethality between MK2 and p53, enhancing anti-tumor responses alone and in combination with cisplatin chemotherapy. (nature.com)
  • For two cells to come together as one, they must recognize one another and merge their outer membranes. (pewtrusts.org)
  • The outer layer of a cell, or a cell membrane, is a complex structure with many different kinds of molecules that are in constant motion, moving fluidly throughout the membrane. (visionlearning.com)
  • From the time cells were first discovered in the mid-1600s, scientists knew that there must be some sort of outer wrapping around the cell to hold the contents of the cell together. (visionlearning.com)
  • Although it was too thin for them to see with simple light microscropes, scientists called this outer wrapping a membrane (in Latin, membrana ), which means a thin layer of skin or tissue. (visionlearning.com)
  • From the 17th century until around the 1960s, the outer membrane of cells was thought to be a simple passive barrier. (visionlearning.com)
  • The ability to form an outer membrane around the organism that separates it from the external world. (dictionary.com)
  • Because most tumors are deficient in one or more aspects of the function of the p53 tumor suppressor, either as a consequence of mutations within p53, or impairment of upstream and downstream modulators of p53 activity 19 , targeting MK2 has the potential to selectively enhance tumor cell killing without increasing the genotoxic effects of chemotherapy on normal p53-wild type tissues. (nature.com)
  • The researchers ran the material through a battery of stretch and impact tests, and showed that, similar to the lobster underbelly, the synthetic material is remarkably fatigue-resistant, able to withstand repeated stretches and strains without tearing. (nanotech-now.com)
  • Chinese researchers, looking for a cure to lung cancer, inject the first ever Crispr-edited cells into a human being. (lifeboat.com)
  • Image of a Komodo dragon By Charlesjsharp - Own work, from Sharp Photography, sharpphotography, CC BY-SA 4.0, via Wikimedia Commons Researchers at George Mason University have created a synthetic version of a peptide found in the blood of Komodo dragons (Varanus komodoensis). (scienceblogs.com)
  • Nov. 10, 2022 Researchers have discovered a new process that uses fuel to control non-living materials, similar to what living cells do. (sciencedaily.com)
  • This explains why researchers are now focusing attention on developing stem cell therapies using postnatal stem cells donated by the patients themselves or their close relatives. (bvsalud.org)
  • June 22, 2015) Chemists and biologists at UC San Diego have succeeded in designing and synthesizing an artificial cell membrane capable of sustaining continual growth, just like a living cell. (blogspot.com)
  • Synthetic vitreous fibers are a group of fibrous inorganic materials that contain aluminum or calcium silicates and other trace oxides and metals, and are made from rock, slag, clay, or glass. (cdc.gov)
  • Maintaining adequate long-term stability is the problem, due to the tendency of membrane liquids to evaporate or dissolve in the phases in contact with them. (wikipedia.org)
  • Synthetic vitreous fibers do not evaporate into air or dissolve in water. (cdc.gov)
  • The membranes we created, though completely synthetic, mimic several features of more complex living organisms, such as the ability to adapt their composition in response to environmental cues," said Neal Devaraj, an assistant professor of chemistry and biochemistry at UC San Diego who headed the research team, which included scientists from the campus' BioCircuits Institute. (blogspot.com)
  • T-cell engaging bispecific antibodies present a promising strategy for cancer immunotherapy and numerous bispecific formats have been developed for retargeting cytolytic T cells toward tumor cells. (biorxiv.org)
  • To explore the therapeutic utility of T-cell engaging bispecific antibodies targeting the receptor tyrosine kinase ROR1, which is expressed by tumor cells of various hematologic and solid malignancies, we used a bispecific ROR1 × CD3 scFv-Fc format based on a heterodimeric and aglycosylated Fc domain designed for extended circulatory half-life and diminished systemic T-cell activation. (biorxiv.org)
  • Using subunit-specific antibodies, however, it is not possible to distinguish between the absence of AMPA receptors and the lack of a particular subunit on the cell surface. (jneurosci.org)
  • Thus, typical HA-specific antibodies neutralize viral infectivity and fully protect against infection when they are present at sufficient concentration in the lining fluid of the respiratory tract, and typical NA-specific antibodies inhibit the release of newly formed virus from infected host cells and thus limit the spread and shedding of virus during infection. (cdc.gov)
  • Because of their potential for broadening vaccine-mediated protection in humans, they have been studied extensively in animals and found to be mediated predominantly by virus-specific memory T cells ( 6 , 7 ), antibodies ( 8 - 10 ), or a combination of both ( 11 - 13 ). (cdc.gov)
  • ABC transporters are membrane proteins that transport various substances from one side of the cell membrane to the other. (nanowerk.com)
  • The transporters are of great medical significance as they play a central role in the multi-drug resistance of cancer cells to chemotherapeutic substances and are associated with various inherited diseases like cystic fibrosis. (nanowerk.com)
  • Chemistry A thin sheet of natural or synthetic material that is permeable to substances in solution. (dictionary.com)
  • Although the total number of NPL sites evaluated for these substances is not known, the possibility exists that synthetic vitreous fibers may be found in the future as more sites are evaluated. (cdc.gov)
  • In a second study, endosomal structures damaged by membrane-destabilizing substances are characterized and their potential improvements on cholesterol conjugated siRNA delivery. (lu.se)
  • Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. (3m.com)
  • Water has to be pushed through a semipermeable membrane that blocks the salt and other impurities from going through. (dictionary.com)
  • Bosemark P, Perdikouri C, Pelkonen M, Isaksson H, Tägil M. The masquelet induced membrane technique with BMP and a synthetic scaffold can heal a rat femoral critical size defect. (lu.se)
  • The key elements of tissue engineering are stem cells, morphogen, and a scaffold of extracellular matrix. (bvsalud.org)
  • The major areas of research that might have application in the development of regenerative endodontic techniques are (a) postnatal stem cells, (b) scaffold materials, (c) morphogen/growth factors, (d) implantation. (bvsalud.org)
  • A lobster s underbelly is lined with a thin, translucent membrane that is both stretchy and surprisingly tough. (nanotech-now.com)
  • When they are done, the casing has transformed from translucent membrane into chewy, wrinkled coat. (dictionary.com)
  • The chemical and physical properties of synthetic membranes and separated particles as well as a choice of driving force define a particular membrane separation process. (wikipedia.org)
  • The best known synthetic membrane separation processes include water purification, reverse osmosis, dehydrogenation of natural gas, removal of cell particles by microfiltration and ultrafiltration, removal of microorganisms from dairy products, and Dialysis. (wikipedia.org)
  • Because the iron oxide keeps the cell undead, kind of like the electrodes attached to Frankenstein's monster, transmembrane proteins are still alive enough to be receptors for active particles. (syfy.com)
  • Po-210 emits alpha particles, which carry high amounts of energy that can damage or destroy genetic material in cells inside the body. (cdc.gov)
  • Controlling membrane dynamics and surface energies, we create these highly stable artificial cell surogates. (gla.ac.uk)
  • Using a similar pressure-regulating mechanism to that found in cells, scientists created an artificial cell that responds to a sudden and possibly catastrophic change in its surroundings. (sciencedaily.com)
  • They created the artificial cell using self-assembled surfactants (chemicals that lower the surface tension between different materials, for example, detergents), sugar, and water. (sciencedaily.com)
  • Cell membranes form selective barriers that protect the cell from the watery environment around them while letting water-insoluble molecules like oxygen, carbon dioxide and some hormones pass through. (visionlearning.com)
  • The most of commercially utilized synthetic membranes in separation industry are made of polymeric structures. (wikipedia.org)
  • We learned that this bouligand structure in the lobster underbelly has high mechanical performance, which motivated us to see if we could reproduce such structures in synthetic materials, Lin says. (nanotech-now.com)
  • These structures, which we have termed protocells, act as a structural analogue of the cell, providing a model chassis that contain the DNA machinery and protein expression systems, necessary to develop new biocatalytic systems. (gla.ac.uk)
  • For those creating materials with new properties, such as greater strength or self-healing, the artificial cells ability to sense a possibly damaging event and respond shows an option for changing material structures in response to stress. (sciencedaily.com)
  • Cell membranes were thought to be passive barriers until the 1960s, but we now know that they are active and responsive structures that serve a critical function as gatekeepers and communicators. (visionlearning.com)
  • The claim is that such structures would display minimal life-like behavior (reproductive and potentially evolutive) if the intravesicle ribozymes catalyze their own replication and the production of membrane molecules at the expenses of certain precursors available in the environment. (frontiersin.org)
  • Regenerative endodontic procedures can be defined as biologically based procedures designed to replace damaged structures, including dentin and root structures, as well as cells of the pulp-dentin complex. (bvsalud.org)
  • This Public Health Statement is the summary chapter from the Toxicological Profile for Synthetic Vitreous Fibers . (cdc.gov)
  • This public health statement tells you about synthetic vitreous fibers (SVFs) and the effects of exposure to them. (cdc.gov)
  • Synthetic vitreous fibers have not been detected in the 1,647 current or former NPL sites. (cdc.gov)
  • If you are exposed to synthetic vitreous fibers, many factors determine whether you'll be harmed. (cdc.gov)
  • The randomly oriented molecular structure of synthetic vitreous fibers is called an amorphous structure. (cdc.gov)
  • There are two broad categories of synthetic vitreous fibers: filaments and wools. (cdc.gov)
  • The primary uses of synthetic vitreous fibers are for heat and sound insulating purposes, to reinforce other materials, and as filtration materials. (cdc.gov)
  • The production and use of synthetic vitreous fibers has increased in recent years because these products are often used as a replacement for asbestos. (cdc.gov)
  • What happens to synthetic vitreous fibers when they enter the environment? (cdc.gov)
  • See Chapters 4 and 5 for more information on the properties and uses of synthetic vitreous fibers. (cdc.gov)
  • Eventually, synthetic vitreous fibers will be broken down if the water or soil is very acidic or very alkaline. (cdc.gov)
  • Synthetic vitreous fibers are not likely to move through soil. (cdc.gov)
  • See Chapter 6 for more information on the behavior of synthetic vitreous fibers in the environment. (cdc.gov)
  • Po-210 is used in some devices to eliminate static electricity in processes such as rolling paper, manufacturing sheet plastics, and spinning synthetic fibers. (cdc.gov)
  • Delivery of siRNA-peptide nanoplexes co-targeting MK2 and XPA to pre-existing p53-deficient tumors in a highly aggressive, immunocompetent mouse model of lung adenocarcinoma improves long-term survival and cisplatin response beyond those of the synthetic lethal p53 mutant/MK2 combination alone. (nature.com)
  • They dubbed the synthetic peptide DRGN-1. (scienceblogs.com)
  • Tyrosine kinase activity in lens membrane preparations was assayed in the presence of a synthetic substrate peptide and [32P]ATP. (nih.gov)
  • The study, published in Small , focuses on the use of LSC derived from human embryonic stem cells, and it was done in collaboration with the Eye Group led by Heli Skottman in Tampere University (Finland), experts in the use of stem cells for ocular applications. (icmab.es)
  • Based on their origin, there are two main types of stem cells - embryonic stem cells (ES cells) and postnatal or adult stem cells (AS cells). (bvsalud.org)
  • Embryonic stem cells are stem cells derived from the inner cell mass of an early, preimplantation stage embryo known as a blastocyst. (bvsalud.org)
  • Because each amphiphilic unit is attached to a flexible micromolecular chain, tens or perhaps hundreds of them can collectively work together and facilitate the entire macromolecule to penetrate through the membrane. (sc.edu)
  • Native-nanoBleach, a single-molecule imaging technique with a spatial resolution of ~10 nm, quantifies the oligomeric distribution of membrane proteins directly from native membranes at endogenous expression levels with their proximal native membrane environment using amphipathic copolymer nanodiscs. (nature.com)
  • The driving force for this is provided by the molecule ATP, a universal energy storage of the cells. (nanowerk.com)
  • While several non-native membrane fusion mechanisms have been demonstrated, few can respond to external stimuli. (rsc.org)
  • This methodology will create new knowledge regarding mechanisms of cell-cell fusion, in addition to providing novel strategies to mitigate muscle disease through cell therapy. (pewtrusts.org)
  • Doug Kellogg's lab is working to elucidate these mechanisms, using biochemistry, genetics, and mathematical modeling to understand signaling networks that are required for control of cell size and cell growth. (ucsc.edu)
  • pCellular activation of latent matrix metalloproteinase-2 (proMMP-2) requires formation of a cell membrane-associated activation complex that involves specific binding between the hemopexin domain of proMMP-2 (PEX) and the C-terminal domain of tissue inhibitor of matrix metalloproteinases-2 (C-TIMP-2). (amrita.edu)
  • When injected into tissue, it destroys the cell membrane. (latimes.com)
  • A thin, flexible layer of tissue that covers, lines, separates, or connects cells or parts of an organism. (dictionary.com)
  • Postnatal stem cells have been sourced from umbilical cord blood, umbilical cord, bone marrow, peripheral blood, body fat, and almost all body tissues, including the pulp tissue of teeth 8 . (bvsalud.org)
  • For that purpose, a new promising process based on a membrane reactor will be realized and characterized experimentally. (europa.eu)
  • Synthetic opioids, primarily fentanyl, caused nearly two-thirds (64%) of all drug overdose deaths in the same 12-month period, up 49% from the year before. (medscape.com)
  • The goal of her team's proposal, she says, is "to improve materials not only for solid oxide fuel cells and electrolyzers, which I study in my own laboratory, but also for gas conversion and thermo-chemical reactors to produce clean fuels, which are Ahmed Ghoniem's area of expertise. (mit.edu)
  • To ensure efficient transplantation of cells, an appropriate substrate is required to affix the LSC to the cornea - a very specific combination of properties have to be achieved for a successful transplant. (icmab.es)
  • Encapsulating molecular components in artificial membranes offers more flexibility in designing circuits. (lifeboat.com)
  • They are also called MIEC (Mixed Ionic Electronic Conductor), ITM (Ion transporting Membranes), OTM (Oxygen transporting Membranes). (europa.eu)
  • One of the winners is a design for metal-oxide surfaces to enable fast oxygen exchange in fuel cells. (mit.edu)
  • RNA interference is an evolutionary conserved gene regulatory mechanism that can be used by introducing exogenous synthetic double-stranded RNAs, so called small interfering RNA (siRNA). (lu.se)
  • The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane. (3m.com)
  • Toward Functional Synthetic Cells: In-Depth Study of Nanoparticle and Enzyme Diffusion through a Cross-Linked Polymersome Membrane. (mpg.de)
  • Under Steve's direction, MAST established an international reputation in the development and application of synthetic carbon materials applied to separations, membranes, fuel cells, catalysis, and automotive applications. (bath.ac.uk)
  • Winning teams will use grants to advance research in areas including fuel cells, solar-powered desalination, and impacts of electric vehicle charging on the power grid. (mit.edu)
  • Synthetic membrane can be fabricated from a large number of different materials. (wikipedia.org)
  • Liquid membranes refer to synthetic membranes made of non-rigid materials. (wikipedia.org)
  • Firstly, they tested the materials for safety on mammalian cells. (nanowerk.com)
  • 1. PUBLIC HEALTH STATEMENT and disposal of synthetic vitreous fiber-containing materials. (cdc.gov)
  • Synthetic membranes have been successfully used for small and large-scale industrial processes since the middle of twentieth century. (wikipedia.org)
  • An artificial membrane, or synthetic membrane, is a synthetically created membrane which is usually intended for separation purposes in laboratory or in industry. (wikipedia.org)
  • Also, they appear to be non-toxic to human cells after testing in Dr. Mitzi Nagarkatti 's laboratory in the School of Medicine . (sc.edu)
  • The goal of my research is to understand how cells fuse. (pewtrusts.org)
  • The investigations were supported by the Protein Research Department at the RUB and funds of the collaborative research centre SFB 642 "GTP and ATP dependent membrane processes", whose speaker is Prof. Dr. Klaus Gerwert. (nanowerk.com)
  • Cell-Ess can deliver fats and cholesterol, boosting the ability of cells to make membranes in either basic research and bioprocessing applications. (genengnews.com)
  • In basic research, as depicted in this image, Cell-Ess can enhance reproducibility because it is 100% synthetic and does not vary in composition from lot to lot. (genengnews.com)
  • Steve was promoted to Research Associate and Project Manager for the scale-up of this catalyst and the associated modified synthetic process, work which ultimately led to the building of one of the largest ammonia plants in the world and promotion to Senior Research Associate with responsibility for the use of carbons in all areas related to BP's operations. (bath.ac.uk)
  • According to Fact MR's recent market research, sales of Dental Membrane and Bone Graft Substitutes to swell at propelled CAGR through 2031, as investment towards expansion of healthcare infrastructure continues rising. (pharmiweb.com)
  • There are limited numbers of publications about ES cells in pulp regeneration, due to the restricted policies regarding ES cell research over the past few years. (bvsalud.org)