Loading...
  • siRNA
  • the other without biotin as functional RNA (i.e., siRNA). (ucsb.edu)
  • Initially, flexible single-stranded RNA is used for dense surface-packing, followed by hybridization with the complementary RNA strand to maximize the assembly of the targeting peptide for cellular uptake and siRNA delivery. (ucsb.edu)
  • transcriptional
  • Streptavidin is devised as a handle to assemble biotinylated cell penetrating peptides (e.g., transactivating transcriptional activator (TAT)), as well as an insulator between the positive charge of TAT and the dense negative charge of RNA. (ucsb.edu)
  • regulation
  • Using the transcription-regulatory network, sRNA targets tend to be under multiple regulation (higher indegree, p-val = 0.013) and the targets usually are important to the transfer of regulatory signals (higher betweenness, p-val = 0.012). (biomedcentral.com)
  • messenger
  • The cfCRF-R1 messenger RNA is highly expressed in the brain, and its distribution pattern correlates well with that of mammalian CRF-R1, except for weak expression in the pituitary. (embl-heidelberg.de)
  • cells
  • In particular, it has been observed that substances classified as angiogenic factors can be mitogenic by affecting DNA synthesis in endothelial cells, thus increasing the rate of endothelial cell proliferation and the rate at which new blood vessels are formed. (freepatentsonline.com)