• Hydroxyapatite nanoparticles (HAP-NPs) form an inorganic portion of the natural bone and are primarily used in tissue engineering due to their anti-inflammatory and anti-toxicity character. (ac.ir)
  • Hydroxyapatite nanoparticles as a novel gene carrier. (ac.ir)
  • 7. Syamchand SS, Sony G. Multifunctional hydroxyapatite nanoparticles for drug delivery and multimodal molecular imaging. (ac.ir)
  • 9. Kadu K, Tripathi R, Kowshik M, Ramanan SR. Morphological Evolution of Hydroxyapatite Nanoparticles, Synthesized via Modified Sol‐Gel and Microemulsion Technique, in Response to Their Synthesis Microenvironment. (ac.ir)
  • The bio-based nanoparticles synthesis and assessment of their potential biomedical applications related research is rapidly emerging. (bvsalud.org)
  • Commercial grade calcium sulfate hemihydrate (CaSO4·0.5H2O, or plaster of paris, PoP) an economically feasible and abundant precursor has been used in (Ca10(PO4)6(OH)2, HAp) synthesis. (metu.edu.tr)
  • HAp synthesis was achieved by reacting 1 M of (NH4)2HPO4 (or 0.5 M of (NH4)2HPO4) solutions with solid calcium sulfate precursors under ambient pressure (1 atm) and hydrothermal-like (2 ± 0.2 atm, 120 °C) conditions. (metu.edu.tr)
  • An important inorganic phase of synthetic bone applications, calcium hydroxyapatite (HA, Ca-10(PO4)(6)(OH)(2)), was prepared as a single-phase and sub-micron bioceramic powder. (metu.edu.tr)
  • Calcium hydroxyapatite (Ca-10(PO4)(6)(OH)(2), HAp) whiskers have been processed using microwave and conventional heating. (bath.ac.uk)
  • Hydroxyapatite (IMA name: hydroxylapatite) (Hap, HAp, or HA) is a naturally occurring mineral form of calcium apatite with the formula Ca5(PO4)3(OH), often written Ca10(PO4)6(OH)2 to denote that the crystal unit cell comprises two entities. (wikipedia.org)
  • Carbonated calcium-deficient hydroxyapatite is the main mineral of which dental enamel and dentin are composed. (wikipedia.org)
  • Calcium-deficient (non-stochiometric) hydroxyapatite, Ca10−x(PO4)6−x(HPO4)x(OH)2−x (where x is between 0 and 1) has a Ca/P ratio between 1.67 and 1.5. (wikipedia.org)
  • Hydroxylapatite is a constituent of calcium phosphate kidney stones. (wikipedia.org)
  • During demineralisation, calcium and phosphorus ions are drawn out from the hydroxyapatite. (wikipedia.org)
  • A periodic layer underneath the impact layer composed of hydroxyapatite with lower calcium and phosphorus content (thus resulting in a much lower modulus) inhibits crack growth by forcing new cracks to change directions. (wikipedia.org)
  • Artificially grown MD was used as a raw material for the production of calcium phosphate, mainly hydroxyapatite bioceramics, to be used in the drug delivery systems as a drug carrier or in the tissue engineering such as bone graft. (hal.science)
  • One approach is to remineralize the lesion body with fluoride, casein phosphopeptide amorphous calcium phosphate (CPP-ACP) or nano-hydroxyapatite (nHAP). (nature.com)
  • Chimie et solubilité des phosphates ce calcium en milieux aqueux. (epfl.ch)
  • The as-synthesized hydroxyapatite powder and the mixture of as-synthesized hydroxyapatite and as-synthesized TCP at a ratio of 70:30, so-called biphasic calcium phosphate (BCP) powder, were compacted under a uniaxial pressing of 10 MPa (HA10, BCP10) and 17 MPa (HA17, BCP17) for a dwell time of 60 s to consolidate the specimens into a bar with dimensions of 16 × 5 × 2 mm for the compressive strength test. (beingmedicos.com)
  • Hydrothermally treated coral was showing agglomerated nodules up to 1-μm size consisting of nanocrystalline hydroxyapatite platelets in the size range of less than 100 nm. (hal.science)
  • Sasikumar S, Vijayaraghavan R. Low temperature synthesis of nanocrystalline hydroxyapatite from egg shells by combustion method. (thejcdp.com)
  • As of 2019[update], the use of hydroxyapatite, or its synthetically manufactured form, nano-hydroxyapatite, is not yet common practice. (wikipedia.org)
  • The aim of the study was to assess the efficacy of three methods of enamel remineralization on initial approximal caries: (1) a nano-hydroxyapatite gel, (2) gaseous ozone therapy, (3) combination of a nano-hydroxyapatite gel and ozone. (nature.com)
  • Patients (n = 92, age 20-30 years) with initial approximal enamel lesions on premolar and molar teeth (n = 546) were randomly allocated to three groups subjected to a 6-months treatment: Group I: domestic nano-hydroxyapatite remineralizing gel, group II: in-office ozone therapy, group III: both domestic remineralizing gel and ozone therapy. (nature.com)
  • Thus nano-hydroxyapatite gel and ozone therapy exert some capacities to remineralize approximal enamel and dentine subsurface lesions of premolar and molar teeth. (nature.com)
  • Moreover, the combination of both methods produces the best effect compared to nano-hydroxyapatite or ozone therapy applied alone. (nature.com)
  • Morphology studies showed that hydroxyapatite particles with the average size of 50 nm were distributed homogeneously in the polymer matrix. (yildiz.edu.tr)
  • A systematic evaluation of mechanical and biocompatibility properties of different volume fractions of hydroxyapatite whiskers in comparison with three commercial dental composites filled with micro- and nanosilica particles was carried out. (hindawi.com)
  • Six groups with different hydroxyapatite whiskers mass fractions were taken into account in order to be compared with the performances of silica particles based composites group. (hindawi.com)
  • Data obtained show better interfacial interaction with filler/matrix until 20 wt% of hydroxyapatite whiskers partially replaced silica particles filler. (hindawi.com)
  • For this reason, in the recent five years hydroxyapatite particles and whiskers have been added as novel bioactive and biocompatible reinforcing filler in dental restorations. (hindawi.com)
  • This information is of primary interest in order to achieve a final consistency and specific formulation of hydroxyapatite whiskers mixed with silica particles filler in resin composite. (hindawi.com)
  • In particular, six different ratios of hydroxyapatite/silica particles were investigated. (hindawi.com)
  • With this aim, different mass fraction of hydroxyapatite based composites and three commercial composites loaded with silica particles were tested and compared in order to verify the effective enhancement in both biocompatibility and mechanical properties. (hindawi.com)
  • A new biomimetic precipitation technique was developed to synthesize hydroxyapatite/collagen nanocomposites. (yildiz.edu.tr)
  • Hydroxyapatite can be synthesized via several methods, such as wet chemical deposition, biomimetic deposition, sol-gel route (wet-chemical precipitation) or electrodeposition. (wikipedia.org)
  • Pd-Si-structured novel mesoporous nanocomposite catalytic materials, having quite high Pd/Si ratios, were synthesized by an acidic direct hydrothermal synthesis route. (metu.edu.tr)
  • During this time, he worked on multiple bio-degradable and biocompatible materials such as bio-ceramics (e.g. hydroxyapatite), mesoporous materials (e.g. (itsligo.ie)
  • The synthesis was realized by reacting solid PoP precursor with 1M of (NH4)2HPO4 aqueous solution, at ambient and mild hydrothermal conditions (2 ± 0.2 atm and 120 °C). The effect of reaction temperature and pressure on PoP to HAp conversion efficiencies and reaction kinetics has been reported. (metu.edu.tr)
  • The findings showed that HAp synthesis can be accomplished by using a single and relatively cheap solid precursor under technological relevant hydrothermal conditions. (metu.edu.tr)
  • We have now succeeded in preparing BPO4 from H3BO3 and P2O5 using hydrothermal synthesis by heating at 160 degreesC for 2 days and obtained a single phase product. (metu.edu.tr)
  • Apart from chemical and material synthesis, Usaid has hands-on experience in different characterisation instruments such as metallurgical microscopes and SEM for the surface imaging of materials, FTIR spectroscopy (identify molecular composition), fatigue testing machine (FTS) and universal testing machine (UTM) to determine the mechanical properties of materials. (itsligo.ie)
  • Taking the inspiration from the biomineral, the wool keratin was selected to modulate the assembly of nanosized hydroxyapatite (HA) crystals via a coprecipitation method. (manchester.ac.uk)
  • Each technique yields hydroxyapatite crystals of varied characteristics, such as size and shape. (wikipedia.org)
  • The mineral ions introduced during remineralisation restore the structure of the hydroxyapatite crystals. (wikipedia.org)
  • If fluoride ions are present during the remineralisation, through water fluoridation or the use of fluoride-containing toothpaste, the stronger and more acid-resistant fluorapatite crystals are formed instead of the hydroxyapatite crystals. (wikipedia.org)
  • Pure hydroxyapatite powder is white. (wikipedia.org)
  • The starting materials CaCO 3 and CaHPO 4 with Ca/P molar ratios of 1.67 and 1.5 were used to produce pure hydroxyapatite and TCP powder following Eqs. (beingmedicos.com)
  • The as-synthesized hydroxyapatite and TCP powder particle size was approximately 4.5 µm measured by Zetasizer (Malvern Panalytical, Malvern, UK). (beingmedicos.com)
  • The non-stoichiometric phases have the hydroxyapatite structure with cation vacancies (Ca2+) and anion (OH−) vacancies. (wikipedia.org)
  • The sites occupied solely by phosphate anions in stoichiometric hydroxyapatite, are occupied by phosphate or hydrogen phosphate, HPO2−4, anions. (wikipedia.org)
  • The result was shown that the hydroxyapatite was 100% pure and stoichiometric ratio Ca/P was 1.718. (envirobiotechjournals.com)
  • Usaid also fabricated osteoinductive porous scaffolds composed of well-known biopolymers (gelatin and chitosan) and hydroxyapatite (HA) by a simple freeze-drying method for bone tissue engineering applications. (itsligo.ie)
  • In fact, it was shown that the incorporation of hydroxyapatite with whiskers morphology can provide larger load transfer and favor toughening mechanisms, thus, increasing flexural modulus and fracture toughness of resins in comparison with conventional silica based fillers [ 6 - 11 ]. (hindawi.com)
  • In addition, hydroxyapatite whiskers (wHA) have been considered the best option as reinforcing filler in comparison with other whiskers based on carbon, ceramic, glass, metal, and polymer due to the absence of cytotoxicity effects [ 12 , 13 ]. (hindawi.com)
  • The effect of Silver substitution on the biocompatibility of hydroxyapatite (HA) under the physiochemical conditions has been investigated. (derpharmachemica.com)
  • In addition, biocompatibility test showed less cytotoxic effect with the addition of 20 wt% of hydroxyapatite in comparison with higher rates. (hindawi.com)
  • To overcome the present lack in the literature about hydroxyapatite based composite, we proposed a systematic analysis of the mechanical and biocompatibility performances of them in comparison with commercial dental composite. (hindawi.com)
  • The chemical method was used for the synthesis of chitosan, silver and chitosan-Silver nanocomposite. (springer.com)
  • Hydroxyapatite is the main mineral component of enamel in teeth. (wikipedia.org)
  • As the main biomineral component in enamel and dentine, hydroxyapatite is responsible for their higher mechanical performances. (hindawi.com)
  • These variations have a marked effect on the biological and mechanical properties of the compound, and therefore these hydroxyapatite products have different clinical uses. (wikipedia.org)
  • In addition, the surface of its appendages is made up of extremely dense hydroxyapatite, layered in a manner which is highly resistant to fracturing. (abovetopsecret.com)
  • It was revealed that the inorganic phase in the nano-composite was carbonate-substituted hydroxyapatite with low crystallinity. (yildiz.edu.tr)
  • article{osti_1543698, title = {Effects of Controlled Crystalline Surface of Hydroxyapatite on Methane Oxidation Reactions}, author = {Oh, Su Cheun and Xu, Jiayi and Tran, Dat T. and Liu, Bin and Liu, Dongxia}, abstractNote = {Hydroxyapatite (HAP, Ca10(PO4)6(OH)2) has a hexagonal prismatic structure that exposes two crystalline surfaces: prism-faceted a- and basal-faceted c-surfaces. (osti.gov)
  • Natural fibrous sepiolite with a high surface area, negative surface charge and porous structure is promising for hydroxyapatite (HAp) mineralization since the clay is naturally abundant and biocompatible. (northumbria.ac.uk)
  • The IBS was synthesized by stirring 5% (w/v) Bovine Hydroxyapatite:Gelatin with a ratio of 45:55 and 2% (w/v) hydropropylmethylcellulose. (envirobiotechjournals.com)
  • In conclusion, the bovine bone waste could be used as the source of hydroxyapatite and could be applied as IBS combined with gelatin and hydroxypropylmethylcellulose. (envirobiotechjournals.com)
  • 5] A. Elkayar, Y. Elshazly & M. Assaad, Properties Of Hydroxyapatite from Bovine Teeth . (uns.ac.id)
  • Hydroxyapatite (HAp) is a major inorganic component of human hard tissues, such as bones and teeth, and its content determines their microstructures and physical properties. (unipi.it)
  • Chemistry: Design and synthesis of several mussel-inspired oligomers and polymers. (itsligo.ie)
  • We observed that a microwave-assisted synthesis takes only 3 to 5 minutes to transform a solid mixture of (NH4)(2)B4O7. (metu.edu.tr)
  • Since the discovery of hydroxyapatite (HA), a bioceramic compound that possesses the ability to activate bone regrowth and bond directly with regenerated bone, it has subsequently become an indispensable biomaterial. (edu.ng)
  • The hydroxyapatite nanocrystal suspension can be prepared by a wet chemical precipitation reaction following the reaction equation below: 10 Ca(OH)2 + 6 H3PO4 → Ca10(PO4)6(OH)2 + 18 H2O The ability to synthetically replicate hydroxyapatite has invaluable clinical implications, especially in dentistry. (wikipedia.org)
  • Hydroxyapatite (HAP, Ca 10 (PO 4 ) 6 (OH) 2 ) has a hexagonal prismatic structure that exposes two crystalline surfaces: prism-faceted a- and basal-faceted c-surfaces. (osti.gov)
  • Journal of Molecular Liquids), and one book chapter on "Carbonated Substituted hydroxyapatite" in Handbook of Ionic Substituted Hydroxyapatites. (itsligo.ie)
  • Up to 50% by volume and 70% by weight of human bone is a modified form of hydroxyapatite, known as bone mineral. (wikipedia.org)
  • this has led to its investigation for potential synthesis and engineering use. (wikipedia.org)
  • This study was aimed to synthesis of Hydroxyapatite from bovine bone by high pressure-steamed, grinded and filtered process with a 80 mesh and characterized by Fourier transform infrared, Scanning Electron Microscopy and X-Ray Diffraction for determining the purity of the hydroxyapatite. (envirobiotechjournals.com)
  • After this threshold, the mechanical performances decrease dramatically due to both the hydroxyapatite agglomerates formation and the low degree of resin conversion. (hindawi.com)