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Cysteine DioxygenaseCysteineSulfur CompoundsTaurineDioxygenasesCarboxy-LyasesSulfatesGlutathioneCysteine EndopeptidasesLipid MetabolismCysteine ProteasesEnergy MetabolismMolecular Sequence DataAmino Acid SequenceKineticsCysteine Proteinase InhibitorsLiverCysteine SynthaseProtein BiosynthesisOxidation-ReductionMutationEscherichia coliBase SequenceGlucoseRNA, MessengerMetabolismCells, CulturedMolecular StructureStereoisomerismCell LineDisulfidesCarbon IsotopesChromatography, High Pressure LiquidSulfhydryl CompoundsBacterial ProteinsProtein Synthesis InhibitorsDNATime FactorsLeucineRecombinant ProteinsMagnetic Resonance SpectroscopyTritiumMethionineCarbon RadioisotopesMutagenesis, Site-DirectedCloning, MolecularBinding SitesStructure-Activity RelationshipFatty AcidsTranscription, GeneticSequence Homology, Amino AcidModels, BiologicalCystineCycloheximideModels, MolecularSubstrate SpecificityCatalysisAmino AcidsElectrophoresis, Polyacrylamide GelProtein BindingBiotransformationAcetatesRNADNA ReplicationDose-Response Relationship, DrugCytochrome P-450 Enzyme SystemMicrosomes, LiverGene Expression RegulationMass SpectrometryCyclizationCathepsinsAdenosine TriphosphateRats, Inbred StrainsHydrogen-Ion ConcentrationCulture MediaSignal TransductionGlycolysisMetabolic Networks and PathwaysSulfurInsulinBiological TransportProteinsCell-Free SystemRats, Sprague-DawleyProtein Structure, TertiaryMolecular WeightMitochondriaCholesterolEnzyme InhibitorsTemperatureIndicators and ReagentsNitrogenProtein ConformationCystatinsRabbitsCattleSequence AlignmentSaccharomyces cerevisiaeDactinomycinPapain

MethionineSulfur metabolismPeptidesNitrogen metabolismAmino acidHomocysteineCarbohydrate metabolismSulfideGlutathioneOxidative stressFattyOrganicEnergy metabolismSulphurGlucoseContributesProteinMicrobialEnzymesEnzymaticDeficiencyCoenzymeAmmoniaCellularPrimarilyMechanismsPlantsCellsEssentialRolesPlantComplexElementFunctionSkinPotential

Methionine5

• Sulfur is incorporated into amino acids such as cysteine and methionine, which are used to build proteins and other important molecules. (wikipedia.org)
• Terrestrial organisms such as plants and microorganisms are also able to incorporate sulfur in organic molecules to produce primary metabolites (e.g., methionine, cysteine) and more complex unique chemical structures with diverse biological roles. (alliedacademies.org)
• Sulphur being an important part of cysteine and methionine, it helps to form the chains of amino acids and in turn helps to form the various secondary plant parts. (vogueitude.com)
• It is also formed in the body by oxidation of the aminoacids cysteine and methionine. (simplymimi.net)
• It is an essential element for life and is found in two amino acids, cysteine and methionine. (cqconcepts.com)

Sulfur metabolism4

• The formation of cysteine is the direct coupling step between sulfur (sulfur metabolism) and nitrogen assimilation in plants. (wikipedia.org)
• Sulfur metabolism in humans is very complicated and plays a central role in redox biochemistry. (alliedacademies.org)
• This review will explore sulfur metabolism related to redox biochemistry and will describe the various classes of sulfur-containing compounds spread all over the natural kingdoms. (alliedacademies.org)
• Potential projects focused on this theme are (1) investigating the contributions of metabolism to prognosis in tick-borne diseases like Lyme's, and (2) the effect of metal contamination on sulfur metabolism of the gut microbiome. (wisc.edu)

Peptides2

• Gut hormones such as gastrin, which stimulate cholecystokinin (CCK) and pepsin, to release secretin and other pancreatic enzymes for protein metabolism (peptides to AA), so regulating neuro-endocrine metabolism, satiety, dopamine action, memory and anxiety, are also sulphur dependent. (nutrition-matters.co.uk)
• CoA is essential for the synthesis of phospholipids, fatty acids, polyketides and non-ribosomal peptides, for the operation of the tricarboxylic acid cycle and in the degradation of lipids 3 . (nature.com)

Nitrogen metabolism2

• It should also be noted that potassium in plants is very mobile, and its deficiency impedes the movement of carbohydrates and nitrogen metabolism, but this action is more indirect than direct. (gardenresident.com)
• Zn2+ is an activator of alcohol dehydrogenase and Mo of nitrogenase during nitrogen metabolism. (ekvij.com)

Amino acid3

• Furthermore, the reduced sulfur is incorporated into cysteine, an amino acid that is a precursor to many other sulfur-containing compounds. (wikipedia.org)
• Beetroot contains betaine and inorganic nitrates Betaine being a naturally-occurring substance and amino acid, found in beetroot which is created by choline, in combination with the amino acid glycine. (nutritiontogo.org)
• The first, C282Y, comprises the substitution of tyrosine for cysteine at amino acid position 282. (medscape.com)

Homocysteine3

• The main generation of H 2 S in cutaneous tissue mostly depends on enzymatic routes using L-cysteine and homocysteine by two pyridoxal-5 - phosphate-dependent enzymes, cystathionine β -synthase (CBS) and cystathionine γ -lyase (CSE). (hindawi.com)
• CBS catalyses the generation of cystathionine from the substrates homocysteine and serine and liberates H 2 S from a combination of cysteine and homocysteine. (hindawi.com)
• Vitamin B6 contributes to the function of our immune system, the regulation of hormones supports the nervous system, is involved in normal cysteine synthesis, normal energy-yielding metabolism, normal homocysteine metabolism, protein and glycogen metabolism and the reduction of tiredness and fatigue. (nutritiontogo.org)

Carbohydrate metabolism1

• Partial breakdown into lactic acid or ethanol and CO2 Note: Bacteria have many different pathways for carbohydrate metabolism based on the enzymes they are able to produce. (studylib.net)

Sulfide1

• Sulfide is incorporated into cysteine, catalyzed by O-acetylserine (thiol)lyase, with O-acetylserine as substrate. (wikipedia.org)

Glutathione1

• The nature of these transporters is not yet fully solved, whether sulfate itself or metabolic products of the sulfur assimilation (O-acetylserine, cysteine, glutathione) act as signals in the regulation of sulfate uptake by the root and its transport to the shoot, and in the expression of the sulfate transporters involved. (wikipedia.org)

Oxidative stress2

• Immunosuppressant neurotoxicity in rat brain models: oxidative stress and cellular metabolism. (mpg.de)
• Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors. (mpg.de)

Fatty1

• Altered fatty acid metabolism and composition in cultured astrocytes under hyperammonemic conditions. (mpg.de)

Organic5

• 1995. Levels and toxicities of selected inorganic and organic contaminants in a swamp environment. (cdc.gov)
• Animals are not able to fix inorganic sulfur into biomolecules and are completely dependent on preformed organic sulfurous compounds to satisfy their sulfur needs. (alliedacademies.org)
• Plants can synthesize organic selenium compounds including Semet from inorganic selenium (Burnell and Shrift, 1977). (90essentials.com)
• When bound to magnesium, the organic glycine molecules protect the inorganic magnesium molecules from adverse interactions with other substances. (healthrangerstore.com)
• Phosphorus is found in both inorganic and organic forms. (gardenresident.com)

Energy metabolism1

• Understanding of the mechanisms that integrate energy metabolism in the entire organism has significantly improved with the application of contemporary biochemical tools for quantifying the fuel substrate metabolism with cutting-edge mouse genetic procedures. (mdpi.com)

Sulphur1

• In the chloroplast particularly, the Sulphur helps in the carbon metabolism by being part of regulatory proteins. (vogueitude.com)

Glucose3

• Hepatocellular apoptosis in mice is associated with early upregulation of mitochondrial glucose metabolism. (mpg.de)
• Imatinib (STI571)-Mediated Changes in Glucose Metabolism in Human Leukemia BCR-ABL-Positive Cells. (mpg.de)
• This type of diabetes is associated with older age, obesity, family history of diabetes, history of gestational diabetes, impaired glucose metabolism, physical inactivity, and race/ethnicity. (gotomydoctor.com)

Contributes2

• Nonenzymatic processes are primarily produced by the decomposition of an inorganic substance, which contributes a little to the amount of H 2 S production. (hindawi.com)
• Biotin is a water-soluble B-vitamin, also called vitamin B7 and formerly known as vitamin H or coenzyme R. It contributes to normal energy-yielding metabolism, normal functioning of the nervous system, normal macronutrient metabolism, normal psychological function, normal hair and skin and the maintenance of normal mucous membranes. (nutritiontogo.org)

Protein1

• This helps in maturing the leaf tissues and also helps in the protein synthesis in the plants as and when required. (vogueitude.com)

Microbial2

• The Majumder Lab employs 'omics-guided biochemistry to study the mechanisms and consequences of microbial inorganic metabolisms on environmental and human health. (wisc.edu)
• As more and more organisms are sequenced and cultured, we are learning about an increasing range of microbial metabolisms and chemistries, especially from anaerobic bacteria. (wisc.edu)

Enzymes1

• We use genomics, enzymology and metabolomics-based technologies to determine the roles for specific genes, enzymes and metabolites in different conditions such as (1) bioplastic-precursor synthesis from waste carbon sources, (2) degradation of recalcitrant plastics in the environment, and (3) the ecology of the interactions between microplastics and Harmful Algal Blooms. (wisc.edu)

Enzymatic1

• The pyridoxal-5 - phosphate-independent enzyme, 3-mercaptopyruvate sulfurtransferase (3-MST), displays enzymatic activity at a pH of 7.4, generating H 2 S from 3-mercaptopyruvate, which is produced by cysteine aminotransferase (CAT) in mitochondria [ 12 - 14 ] (Figure 1 ). (hindawi.com)

Deficiency1

• With a lack of nitrogen, the synthesis of the normal amount of chlorophyll is gradually disrupted, as a result of which, with its extreme deficiency, chlorosis of both older and young leaves develops. (gardenresident.com)

Coenzyme1

• This element is a component of cystine, cysteine and other amino acids, biotin, thiamine, coenzyme A and many other compounds belonging to the sulfhydryl group. (gardenresident.com)

Ammonia1

• On the whole, the nitrate and the ammonia are the most important forms in which the inorganic nitrogen can become a part of the plant. (vogueitude.com)

Cellular1

• Renewing interest in the study of intermediate metabolism and cellular bioenergetics is brought on by the global increase in the prevalence of metabolic illnesses. (mdpi.com)

Primarily1

• These elements are primarily required to main the metabolism of the plant and also helps in the regular photosynthesis mechanism on the whole. (vogueitude.com)

Mechanisms1

• Using a systems-level combination of genomics, metabolomics and biochemistry, we aim to elucidate the mechanisms of how environmental factors cause changes to an organism's metabolism and result in the observed phenotype. (wisc.edu)

Plants1

• The metabolism of selenocompounds in plants has been summarized (Whanger, 1989). (90essentials.com)

Cells1

• Several unexpected findings in genetically altered mice have prompted research into the direction of intermediate metabolism of skeletal cells. (mdpi.com)

Essential4

• Which of these CODHs that are essential in the CO metabolism of A. fulgidus remains unknown. (hindawi.com)
• Based upon the above criteria only a few elements have been found to be absolutely essential for plant growth and metabolism. (ekvij.com)
• In contrast, we show that impC is essential for mycobacterial growth under the conditions we used, and suggest it may be required in the early stages of mycothiol synthesis. (biomedcentral.com)
• [4] Endogenously synthesized RLA is essential for aerobic metabolism. (curecrowd.com)

Roles1

• In this review, we discuss recent advances in understanding H 2 S and its antioxidant effects on skin pathology, the roles of altered H 2 S metabolism in skin disorders, and the potential value of H 2 S as a therapeutic intervention in skin diseases. (hindawi.com)

Plant1

• c) The element must be directly involved in the metabolism of the plant. (ekvij.com)

Complex2

• The synthesis of O-acetylserine is catalyzed by serine acetyltransferase and together with O-acetylserine (thiol)lyase it is associated as enzyme complex named cysteine synthase. (wikipedia.org)
• The bifunctional CODH ( cdhAB-2 ) is predicted to play an ubiquitous role in the metabolism of CO, and a novel nitrate reductase-associated respiratory complex was induced specifically in the presence of sulfate. (hindawi.com)

Element1

• It is no coincidence that marine organisms are one of the most important sources of sulfur natural products since most of the inorganic sulfur is metabolized in ocean environments where this element is abundant. (alliedacademies.org)

Function2

• The phylogenetically oldest and best documented function of taurine is conjugation with bile acids in bile salt synthesis [ 2 , 3 ]. (intechopen.com)
• Pathophysiological abnormalities related to altered H 2 S metabolism and function have been demonstrated in various dermatoses, such as psoriasis, vitiligo, and even melanoma [ 7 - 11 ]. (hindawi.com)

Skin1

• The aberrant metabolism of H 2 S is involved in the pathogenesis of several skin diseases, such as vascular disorders, psoriasis, ulcers, pigment disorders, and melanoma. (hindawi.com)

Potential1

• Macrocyclic Gd3+ Chelates Attached to a Silsesquioxane Core as Potential Magnetic Resonance Imaging Contrast Agents: Synthesis, Physicochemical Characterization, and Stability Studies. (mpg.de)