Myelodysplastic SyndromesMyeloproliferative DisordersBone MarrowJanus Kinase 2Primary MyelofibrosisMyelodysplastic-Myeloproliferative DiseasesPolycythemia VeraThrombocythemia, EssentialBone Marrow CellsSyndromeAnemia, RefractoryBone Marrow NeoplasmsLeukemia, Myelomonocytic, ChronicBone Marrow TransplantationReceptors, ThrombopoietinAnemia, Refractory, with Excess of BlastsLeukemia, Myeloid, AcuteBone and BonesThrombocytosisBone Marrow DiseasesLeukemia, MyeloidHematopoietic Stem CellsLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeMutationAnemia, SideroblasticLeukemia, Myelomonocytic, JuvenileBone Marrow ExaminationChromosomes, Human, Pair 5LeukemiaHematologic NeoplasmsSplenomegalyLeukemia, Myelogenous, Chronic, BCR-ABL PositiveProto-Oncogene Proteins c-cblKaryotypingPrognosisHematopoiesisAzacitidineChromosome AberrationsAnemia, AplasticBlast CrisisPhiladelphia ChromosomeBone RemodelingMegakaryocytesTreatment OutcomePreleukemiaDown SyndromePancytopeniaMyeloid Progenitor CellsHematologyMonosomyTransplantation, HomologousDNA Mutational AnalysisHematopoietic Stem Cell TransplantationAcute DiseaseThalidomideJanus KinasesAntigens, CD34Chromosomes, Human, Pair 7Megakaryocyte Progenitor CellsMice, Inbred C57BLColony-Forming Units AssaySTAT5 Transcription FactorDisease ProgressionCell Transformation, NeoplasticMetabolic Syndrome XBone DensityMegakaryocyte-Erythroid Progenitor CellsGranulocytesMutation, MissenseMyelopoiesisCytogenetic AnalysisFlow CytometryChromosome DeletionNeoplasms, Second PrimaryCell DifferentiationCell ProliferationClonal EvolutionBlood Cell CountPhenotypeFusion Proteins, bcr-ablGranulocyte Precursor CellsAntineoplastic AgentsBone ResorptionWhole-Body IrradiationErythropoietinCytogeneticsHematologic DiseasesPoint MutationAmino Acid SubstitutionGranulocyte Colony-Stimulating FactorBone NeoplasmsGene Knock-In TechniquesTrisomySurvival AnalysisImmunophenotypingTranslocation, GeneticProto-Oncogene ProteinsCells, CulturedProtein Kinase InhibitorsPolymerase Chain Reaction