Myeloproliferative DisordersMyelodysplastic SyndromesJanus Kinase 2Primary MyelofibrosisMyelodysplastic-Myeloproliferative DiseasesPolycythemia VeraThrombocythemia, EssentialSyndromeAnemia, RefractoryLeukemia, Myelomonocytic, ChronicReceptors, ThrombopoietinBone Marrow NeoplasmsAnemia, Refractory, with Excess of BlastsLeukemia, Myeloid, AcuteThrombocytosisLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeLeukemia, MyeloidBone MarrowMutationLeukemia, Myelomonocytic, JuvenileAnemia, SideroblasticChromosomes, Human, Pair 5Proto-Oncogene Proteins c-cblSplenomegalyHematologic NeoplasmsHematopoietic Stem CellsAzacitidineKaryotypingLeukemia, Myelogenous, Chronic, BCR-ABL PositivePrognosisLeukemiaChromosome AberrationsPhiladelphia ChromosomeBlast CrisisDown SyndromeBone Marrow DiseasesHematologyMonosomyPreleukemiaDNA Mutational AnalysisTreatment OutcomeMyeloid Progenitor CellsJanus KinasesThalidomideChromosomes, Human, Pair 7Bone Marrow CellsMegakaryocyte Progenitor CellsMegakaryocytesMetabolic Syndrome XSTAT5 Transcription FactorMegakaryocyte-Erythroid Progenitor CellsMutation, MissenseDisease ProgressionCell Transformation, NeoplasticPancytopeniaAnemia, AplasticChromosome DeletionAcute DiseaseCytogenetic AnalysisClonal EvolutionNeoplasms, Second PrimaryMyelopoiesisAmino Acid SubstitutionPoint MutationFusion Proteins, bcr-ablGene Knock-In TechniquesGranulocyte Precursor CellsProtein Kinase InhibitorsTrisomyHematopoietic Stem Cell TransplantationAntineoplastic AgentsCytogenetics