Myeloproliferative DisordersMyelodysplastic-Myeloproliferative DiseasesMyelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicAnemia, RefractoryThrombocytosisAnemia, SideroblasticPolycythemia VeraJanus Kinase 2Primary MyelofibrosisThrombocythemia, EssentialLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, Myelomonocytic, JuvenileSplenomegalyHematopoiesis, ExtramedullaryFusion Proteins, bcr-ablReceptors, ThrombopoietinBone MarrowLeukocytosisGenes, ablOncogene Proteins, FusionSTAT5 Transcription FactorSyndromeLeukemia, Myeloid, AcuteHematopoietic Stem Cellsfms-Like Tyrosine Kinase 3Bone Marrow TransplantationMutationBone Marrow CellsGene Expression Regulation, LeukemicCell Transformation, NeoplasticAnemia, Refractory, with Excess of BlastsLeukemiaBenzamidesMyeloid CellsHematopoiesisRetroviridaePyrimidinesTranslocation, GeneticMutation, MissenseLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeReceptors, ErythropoietinPiperazinesLeukemia, MyeloidMice, Inbred C57BLDisease Models, AnimalBone Marrow NeoplasmsSignal TransductionProtein-Tyrosine KinasesTransduction, GeneticCell ProliferationDown SyndromeProto-Oncogene ProteinsMice, KnockoutChromosomes, Human, Pair 5PhenotypeLeukemia, Neutrophilic, ChronicFlow CytometryMice, Inbred BALB CMice, TransgenicMegakaryocytesKaryotypingBlast CrisisCells, CulturedSarcoma Viruses, MurineGranulocytesChromosome AberrationsPreleukemia