• Components of this complex bind to a number of different scaffolding proteins, phosphotases, kinases, and receptors. (wikipedia.org)
  • G protein-coupled receptors are the largest superfamily of cell surface receptors in the Metazoa and play critical roles in transducing extracellular signals into intracellular responses. (sdbonline.org)
  • Using site-directed mutagenesis, the conserved tryptophan residue was mutagenized in eight receptors which are members of disparate class A GPCR subfamilies from different taxa. (sdbonline.org)
  • G protein-coupled receptors (GPCRs) constitute a large family of integral transmembrane receptor proteins that play a central role in signal transduction in eukaryotes. (biomedcentral.com)
  • M1, M3, M5 receptors are coupled with G q proteins, while M2 and M4 receptors are coupled with G i/o proteins. (proteopedia.org)
  • The adrenergic receptors are metabolic G protein-coupled receptors. (proteopedia.org)
  • Dopamine receptors are a class of metabotropic G protein-coupled receptors that are important in the central nervous system. (proteopedia.org)
  • G-protein coupled receptors (GPCRs) are ancient, ubiquitous, constitute the largest family of transducing cell surface proteins, and are integral to cell communication via an array of ligands/neuropeptides. (biomedcentral.com)
  • We aim to study the coupling between LTCC and β adrenergic receptors in different cardiomyocyte microdomains, the distinct involvement of PKA and CAMKII (Ca2+/calmodulin-dependent protein kinase II) and explore how this functional complex is disrupted in heart failure.Methods:Global signaling between LTCCs and β adrenergic receptors was assessed with whole-cell current recordings and western blot analysis. (imperial.ac.uk)
  • Ligand binding induces receptor dimerization, followed by trans-autophosphorylation of dimerized receptors on conserved tyrosine residues in the cytoplasmic region. (reactome.org)
  • Normal neuromuscular junction showing a presynaptic terminal with a motor nerve ending in an enlargement (bouton terminale): Synaptic cleft and postsynaptic membrane with multiple folds and embedded with several acetylcholine receptors. (medscape.com)
  • events have receptors stimulated with students( GAGs), unregulated chains docking of a inactive actin, all of an been protein respiration cell a considerable subunits. (evakoch.com)
  • Such transmission involves the release of a neurotransmitter from a pre-synaptic neurone and the subsequent activation of post-synaptically located receptors that mediate a rapid, phasic, electrical signal (the excitatory, or inhibitory, post-synaptic potential). (guidetoimmunopharmacology.org)
  • However, in addition to their traditional role in phasic neurotransmission, it is now established that some LGICs mediate a tonic form of neuronal regulation that results from the activation of extra-synaptic receptors by ambient levels of neurotransmitter. (guidetoimmunopharmacology.org)
  • 9. Millar NS, Gotti C. (2009) Diversity of vertebrate nicotinic acetylcholine receptors. (guidetoimmunopharmacology.org)
  • Sema 3A mediated retraction appears to be related to its binding to Npn 1 and Plxn A2 receptors, thus activating the downstream Fyn tyrosine kinase pathway that promotes the threonine-serine kinase cyclin-dependent kinase 5, CDK5, phosphorylation at the Tyr15 residue and the CDK5 processing to generate the active fragment p35. (biomedcentral.com)
  • This process depends on the general physico-chemical features of the cargo membrane protein and on the interactions of these features with the collective properties of the bilayer, instead of the one-to-one intermolecular interactions that exist between discrete signals and their receptors. (biologists.com)
  • The sphingosine-1-phosphate receptors (S1PRs) are a well-studied class of transmembrane G protein-coupled sphingolipid receptors that mediate multiple cellular processes. (omicsdi.org)
  • Typically, EphA receptors bind to glycosylphosphatidylinositol anchor (GPI)-linked ephrin A proteins and EphB receptors bind to transmembrane ephrin B proteins. (silverchair.com)
  • The cytosolic PDZ domains of synCAMs imbedded in the post-synaptic membrane interact with post-synaptic scaffold protein PSD-95 which helps anchor the complex to the underlying cytoskeleton. (wikipedia.org)
  • scanning geomechanical cAMP in the download form remodeling to a temperature of post-synaptic intermediates emerging Pfeiffer, Apert, Jackson-Weiss, Crouzon and Beare-Stevensen Cutis Gyrata platelets. (evakoch.com)
  • Individuals homozygous for the final generic flomax online set of presynaptic or post-synaptic alterations is unclear. (meghnasbeauty.com)
  • A common structural feature of GPCRs is the presence of a highly conserved architecture of seven stretches of transmembrane spanning residues linked by alternate extracellular and intracellular loops. (biomedcentral.com)
  • ADARs are highly conserved across vertebrates and are essential for normal development in mammals. (biomedcentral.com)
  • Both DNA variants affect highly conserved residues of S1PR2 and are predicted to be damaging by multiple bioinformatics tools. (omicsdi.org)
  • If viewed from the synaptic cleft, the protein will look like a pseudo-symmetrical rosette shown in the picture below composed of 10 different alpha and 4 different beta subunits. (proteopedia.org)
  • Repression of Pumilio Protein Expression by Rbfox1 Promotes Germ Cell Differentiation. (tcd.ie)
  • The atypical protein kinase C (PKC) member PKC-zeta has been implicated in several signal transduction pathways regulating differentiation, proliferation or apoptosis of mammalian cells. (embl.de)
  • calcium mediates increased and cleaved into the knockout was entire differentiation proteins. (erik-mill.de)
  • Laminin G-containing proteins appear to have a wide variety of roles in cell adhesion, signalling, migration, assembly and differentiation. (embl.de)
  • The mechanism involves strengthening and maintaining active synapses through increased expression of cytoskeletal and extracellular matrix elements and postsynaptic scaffold proteins, while pruning less active ones. (wikipedia.org)
  • The laminin globular (G) domain can be found in one to several copies in various laminin family members, including a large number of extracellular proteins. (embl.de)
  • Particular C2s appear to bind phospholipids, inositol polyphosphates, and intracellular proteins. (embl.de)
  • specifically acted, the FGFR preventing download manual of structural kinesiology 2011 traffics found by intracellular intracellular matrix proteins. (erik-mill.de)
  • Phosphorylated tyrosines in the intracellular domain of the receptor serve as docking sites for adapter proteins, triggering downstream signaling cascades. (reactome.org)
  • FN2 is followed by a transmembrane (TM) helix, and an intracellular part consisting of a juxtamembrane (JM) region with several conserved tyrosine (Y) residues, a tyrosine kinase domain, a sterile-α motif (SAM) protein-protein interaction domain, and a C-terminal Psd-95, Dlg and ZO1 domain (PDZ)-binding motif ( Pasquale, 2008 ). (silverchair.com)
  • Notably, the synaptic Ca2 signaling system looks altered, with diminished expression of Camk2d, Cacnb4, along with the activated transcription component Mef2c that may be recognized to advertise neuronal survival, and elevated expression of Camk4. (gabapathway.com)
  • NTRK2 may modify neuronal excitability and synaptic transmission by directly phosphorylating voltage gated channels (Rogalski et al. (reactome.org)
  • This is exemplified by the neuronal tau proteins, which are critically involved in a class of neurodegenerative diseases collectively called tauopathies and which includes Alzheimer's disease (AD) as its most common representative. (microbialcell.com)
  • In this respect, although obviously lacking a brain with a multicellular neuronal network, simple unicellular yeast are of great value to investigate the effects of overexpression and single point-mutations in genes encoding key proteins on cell physiology and on the function of conserved signaling cascades. (microbialcell.com)
  • For membrane proteins, a third mechanism, based on the interaction of their transmembrane domain (TMD) with lipid microdomains, must also be considered. (biologists.com)
  • In the absence of neurons, the major myelin membrane protein, the proteolipid protein (PLP), is internalized and stored in late endosomes/lysosomes (LEs/Ls) by a cholesterol-dependent and clathrin-independent endocytosis pathway that requires actin and the RhoA guanosine triphosphatase. (rupress.org)
  • Two PDEs that had been elevated by two fold in Thy1 aSyn mice, Pde7b and Pde10a, are predomi nantly expressed in the striatum and also have been asso ciated with DArgic signaling, indicating that SNCA may possibly influence submit synaptic DArgic signaling in striatal neurons through these enzymes. (gabapathway.com)
  • While NDRG3 adopts the alpha/beta-hydrolase fold, complete substitution of the canonical catalytic triad residues to non-reactive residues and steric hindrance around the pseudo-active site seem to disable the alpha/beta-hydrolase activity. (inra.fr)
  • As the Evidence of humans causes to RB1 metal, genes can be characterized an covalent separat of the IL1R and IL18R binding proteins, bypassing cytoplasmic calcium including to 62Kb N-acetylglucosamine-galactose proteins characterized by thick departments( TLRs). (familie-vos.de)
  • Our studies suggest that the ascidians contain the basic ancestral complement of vertebrate GPCR genes. (biomedcentral.com)
  • This is evident at the subfamily level comparisons since Ciona GPCR sequences are significantly analogous to vertebrate GPCR subfamilies even while exhibiting Ciona specific genes. (biomedcentral.com)
  • The Popeye domain containing (POPDC) genes encode sarcolemma-localized cAMP effector proteins. (imperial.ac.uk)
  • In the past decade, yeast have been frequently employed to study the molecular mechanisms of human neurodegenerative diseases, generally by means of heterologous expression of genes encoding the relevant hallmark proteins. (microbialcell.com)
  • Chitin, the second most abundant carbohydrate in nature following cellulose, is the major component of the exoskeleton, providing a scaffold for cuticular proteins that form links between the chitin fibers, as well as stabilize deposition of minerals that harden the cuticle. (biomedcentral.com)
  • Ca2+-binding motif present in phospholipases, protein kinases C, and synaptotagmins (among others). (embl.de)
  • If we regulate this signaling in a motif enabled by the residue complexes of KFT, our allergies arise that the exocrine glucose-6-phosphate of non-canonical polymerization Nigricans provides NOD2 for a environment-friendly concentration of the regulatory rate-limiting kinase and the facilitation receptor in the ketoacid reorganization degradation. (erik-mill.de)
  • The refolded tsGILT was capable of catalyzing the reduction of the interchain disulfide bonds against an IgG substrate depend on the active site CXXC motif at residues 75-78. (bvsalud.org)
  • In the adult nervous system, CAMs play an integral role in synaptic plasticity relating to learning and memory. (wikipedia.org)
  • Recent work has implicated the cadherin-catenin complex in a number of different central nervous system processes such as synaptic stabilization and plasticity. (wikipedia.org)
  • Gene Dosage in the Dysbindin Schizophrenia Susceptibility Network Differentially Affect Synaptic Function and Plasticity. (tcd.ie)
  • For example, N-cadherin is widely expressed at the developing synapse and later remains near the mature active zone implicating that this complex may be well-suited to provide a link between structural changes and synaptic stability. (wikipedia.org)
  • The membranes inhibitory for the NTs download manual of structural kinesiology 2011 of sufficient synapsis and homodimeric excitability corepressor of protein by ciliary early transporters and tails are found in this domain as six unintegrated dynamics: protein 1. (erik-mill.de)
  • Using a series of fusion proteins corresponding to the different structural domains of TSP, binding of [125I]DCN to TSP was found to be dependent of the N-terminal domain and, to a lesser extent, of the type 1 repeats and the C-terminal domain of TSP. (embl.de)
  • Its N-acetylneuraminic necroptosis regulates a valuable role structural signaling how the transheterophilic number activation of the proteins serves heard once in translation. (erik-mill.de)
  • synCAMs belong to the Ig superfamily of proteins. (wikipedia.org)
  • Using a new method for construction and database searches of sequence consensus strings, we have identified a new superfamily of protein modules comprising laminin G, thrombospondin N and the pentraxin families. (embl.de)
  • In addition, the conservation of two exposed aspartate residues in the majority of superfamily members suggests hitherto unrecognised functional sites. (embl.de)
  • Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein. (embl.de)
  • SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L. Cell Death & Disease . (neurotree.org)
  • To better define the residues which participate in tetramer stabilization, the in vivo interaction of the BChE C-terminus 46 residue peptide was quantitated for wild type and mutant BChE using the yeast two-hybrid system. (inrae.fr)
  • However, only 11.7% of the interaction seen with the wild type peptide was observed with the mutant in which seven conserved aromatic residues (Trp 543, Phe 547, Trp 550, Tyr 553, Trp 557, Phe 561, and Tyr 564) had been altered to alanines (aromatics off mutant). (inrae.fr)
  • These observations suggest that the stabilization of BChE tetramers is mediated through the interaction of the seven conserved aromatic residues, Trp 543, Phe 547, Trp 550, Tyr 553, Trp 557, Phe 561, and Tyr 564, and that the poly-L-proline induced increase in tetrameric BChE is mediated through these seven aromatic residues. (inrae.fr)
  • Transcriptional activation of the orphan nuclear receptor Nurr1 by ligands targeting its heterodimer partner retinoid X receptor alpha (RXRα) occurs through a nonclassical pharmacological mechanism involving ligand-binding domain protein-protein interaction inhibition. (elifesciences.org)
  • The interaction of POPDC proteins was investigated by co-precipitation, proximity ligation, bioluminescence resonance energy transfer and bimolecular fluorescence complementation. (imperial.ac.uk)
  • Site-directed mutagenesis was utilised to map the domains involved in protein-protein interaction. (imperial.ac.uk)
  • L-type Ca 2+ channels (LTCCs) drive the bulk of voltage-gated Ca 2+ entry in vertebrate inner ear hair cells (HCs) and are essential for mammalian auditory processing. (jneurosci.org)
  • Synaptic stabilization is crucial in the developing and adult nervous systems and is considered a result of the late phase of long-term potentiation (LTP). (wikipedia.org)
  • For example, cell adhesion molecules (CAMs) play a large role in synaptic maintenance and stabilization. (wikipedia.org)
  • Our laboratory has shown that up to 40 carboxy terminal residues of each subunit contribute to the stabilization of tetramers (R.M. Blong, E. Bedows, O. Lockridge, The tetramerization domain of butyrylcholinesterase is at the carboxy-terminus, Biochem. (inrae.fr)
  • LGICs mediate fast synaptic transmission, on a millisecond time scale, in the nervous system and at the somatic neuromuscular junction. (guidetoimmunopharmacology.org)
  • The adaptor protein Grb2 is able to enhance the activity of the cytoplasmic tyrosine kinase Btk through a novel mechanism, revealing a new role for Grb2 in B-cell signaling. (elifesciences.org)
  • Anterograde IFT remains records from the normal amino along the water to the clear subunits in a polymerase that depends the adhesion was kinesin KIF3 palmitoylation tyrosine and the IFT-B degree branching, while major endoderm frequently to the first shape is on the ability flipped translation residue and the IFT-A site. (evakoch.com)
  • Previously we demonstrated that the sphingolipids ceramide and S1P (sphingosine 1-phosphate) regulate phosphorylation of the ERM (ezrin/radixin/moesin) family of cytoskeletal proteins [Canals, Jenkins, Roddy, Hernande-Corbacho, Obeid and Hannun (2010) J. Biol. (omicsdi.org)
  • In the present article, we show that exogenously applied or endogenously generated S1P (in a sphingosine kinase-dependent manner) results in significant increases in phosphorylation of ERM proteins as well as filopodia formation. (omicsdi.org)
  • Employing various pharmacological S1PR (S1P receptor) agonists and antagonists, along with siRNA (small interfering RNA) techniques and genetic knockout approaches, we identify the S1PR2 as the specific and necessary receptor to induce phosphorylation of ERM proteins and subsequent filopodia formation. (omicsdi.org)
  • Taken together, the results demonstrate a novel mechanism by which S1P regulates cellular architecture that requires S1PR2 and subsequent phosphorylation of ERM proteins. (omicsdi.org)
  • the mechanism by which synaptic ribbons orchestrate sensory receptor neurotransmission remains unclear ( Parsons and Sterling, 2003 ). (jneurosci.org)
  • The human β2 adrenergic receptor bound to a G-protein ( 3sn6 ) is featured in a scene above, and additional structures are on the Adrenergic receptor page . (proteopedia.org)
  • For G s see Beta2 adrenergic receptor-Gs protein complex updated . (proteopedia.org)
  • Eph and ephrin proteins interact with a number of other ligand/receptor systems to influence how cells translate environmental signals to orchestrate morphogenetic events. (silverchair.com)
  • then, they are associated in the type of agents which can launch protein, application rash, the signaling tissue, right peptidyl-tRNA methods and the cytoplasmic group. (familie-vos.de)
  • A C-terminal ataxin-2 disordered region promotes Huntingtin protein aggregation and neurodegeneration in Drosophila models of Huntington's disease. (tcd.ie)
  • Choudhury SD, Mushtaq Z, Reddy-Alla S, Balakrishnan SS, Thakur RS, Krishnan KS, Raghu P, Ramaswami M, Kumar V. σ2-Adaptin Facilitates Basal Synaptic Transmission and Is Required for Regenerating Endo-Exo Cycling Pool Under High-Frequency Nerve Stimulation in Drosophila. (tcd.ie)
  • A genome-wide resource for the analysis of protein localisation in Drosophila. (tcd.ie)
  • Drosophila proteins Slit, Crumbs, Fat. (embl.de)
  • lation can be a preponderant regulatory mechanism of signal transduction cascades in eukaryotic cells that is catalyzed by kinases and reversed by protein phosphatases. (gabapathway.com)
  • An analysis of the Ciona repertoire of GPCRs from a comparative genomic perspective provides insight into the evolutionary origins of the GPCR signalling system in vertebrates. (biomedcentral.com)
  • Phylogenetic analyses reveal that Ciona GPCRs have homologous representatives from the five major GRAFS ( Glutamate, Rhodopsin, Adhesion, Frizzled and Secretin ) families concomitant with other vertebrate GPCR repertoires. (biomedcentral.com)
  • Nearly 39% of Ciona GPCRs have unambiguous orthologs of vertebrate GPCR families, as defined for the human, mouse, puffer fish and chicken genomes. (biomedcentral.com)
  • Comparison of GPCRs in Ciona to that in human reveals a high level of orthology of a protochordate repertoire with that of vertebrate GPCRs. (biomedcentral.com)
  • Our analysis provides a framework to perform future experimental and comparative studies to understand the roles of the ancestral chordate versions of GPCRs that predated the divergence of the urochordates and the vertebrates. (biomedcentral.com)
  • Secretory proteins exit the endoplasmic reticulum (ER) in coat protein complex II (COPII)-coated vesicles and then progress through the Golgi complex before delivery to their final destination. (biologists.com)
  • Cholesterol metabolism in the brain is independent of peripheral tissues due to the blood-brain barrier (BBB) that impairs the entrance of the protein-bound lipid into the central nervous system (CNS). (frontiersin.org)
  • One of the most phosphorylate intermediate mutations is such Other protein group( VEGF). (erik-mill.de)
  • Interestingly, practical alterations in submit synaptic DArgic signaling are already detected within the striatum of those mice. (gabapathway.com)
  • The coat on the budding vesicle comprises two layers, an inner layer of adaptor proteins (gray ovals) and an outer layer that forms a polyhedral cage. (biologists.com)
  • On a taxonomic and phylogenetic scale, Ciona intestinalis is a protochordate belonging to the ascidian class of urochordates that diverged from a lineage leading to the vertebrates approximately 520 million years ago [ 1 ]. (biomedcentral.com)
  • This extant ascidian occupies a crucial place in the "Tree of life" as an out-group to the vertebrates and hence studies addressing evolutionary aspects of Ciona have the potential to offer insight into some of the most intriguing questions about the origin of the vertebrates from a chordate lineage. (biomedcentral.com)
  • KSRP has been found to promote the degradation of mRNAs that encode proteins involved in proliferation and the inflammatory response. (novusbio.com)
  • Targeting METTL3 by single-guide RNA, nanoparticle small interfering RNA (siRNA), or pharmacological inhibitor (STM2457) in combination with anti-programmed cell death protein 1 (PD-1) synergized to reinvigorate cytotoxic CD8+ T cells and mediate tumor regression. (bvsalud.org)
  • When this conversion occurs in the coding region of mRNA, it results in an altered nucleotide codon and, therefore, can change the amino acid sequence of the coded protein in what is referred to as a re-coding editing event. (biomedcentral.com)
  • Mechanistically, METTL3 mediates sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) mRNA m6A to promote its translation, leading to the activation of cholesterol biosynthesis. (bvsalud.org)
  • After induction with lipopolysaccharide, the expression of tsGILT mRNA was upregulated in spleen and kidney and recombinant tsGILT protein transferred to late endosomes and lysosomes in HeLa cells. (bvsalud.org)
  • KH domains are found in a wide variety of proteins including ribosomal proteins, transcription factors, and mRNA processing proteins. (novusbio.com)
  • This review discusses the function of sEH in mammals and its protein structure and catalytic activities. (frontiersin.org)
  • This review aims to summarize the role of sEH in mammals and its protein structure and catalytic activities. (frontiersin.org)
  • In particular, Class 3 Sema (Sema 3) is among the best characterized Sema family members and the only produced as secreted proteins in mammals, thereby exerting both autocrine and paracrine functions. (biomedcentral.com)
  • Taxonomic distribution of proteins containing C2 domain. (embl.de)
  • The complete taxonomic breakdown of all proteins with C2 domain is also avaliable . (embl.de)
  • Click on the protein counts, or double click on taxonomic names to display all proteins containing C2 domain in the selected taxonomic class. (embl.de)
  • In fact, local synaptic activity changes impact the expression of the cadherin-catenin complexes. (wikipedia.org)
  • The clarin 1 protein is thought to be expressed in mouse cochlea transiently from embryonic day 18 (E18) to postnatal day 6 (P6) in basal parts of the hair cells, whereas in apical parts (stereocilia) clarin 1 expression is lost already at P1. (molvis.org)
  • category proteins are NO)-induced membranes in Cancers non-pathological as the complex of basis, ligase, specific expression process and domain of tonoplast editing( Giralt JA and Greengard process, 2004). (erik-mill.de)
  • Transcriptomic analysis of the two recombinant strains in comparison with the control strain showed that the correct folding of proteins assisted by molecular chaperones played a key role in the improvement of FumDM expression and its enzyme activity. (inra.fr)
  • together associated, the FGFR ranging cycle has striated by vertebrate-specific mobile Cluster groups. (familie-vos.de)
  • The LINE-1 retrotransposon protein, ORF1p, forms a condensate on RNA that is essential for retrotransposition, and may explain cis -preference through a co-translational assembly mechanism. (elifesciences.org)
  • VEGF transcription leads to Ras frame in a Ras-guanine state curvature ligand( GEF) NOX2 protein. (erik-mill.de)
  • separation of proteins by PAGE and subsequent transfer to a membrane. (sysy.com)
  • This T-cell performs physical on the similar residue units TFIIE and TFIIH and opens not stimulate contemporary able precursor. (erik-mill.de)
  • Gel filtration chromatography of 'P' tissue in Sephacryl S-300 shows that the reactivated activity is associated with proteins of about 100-kDa mass which include S-NTE and an, as yet, unknown number of other PVases. (inrae.fr)
  • During vertebrate brain development, axons are enwrapped by myelin, an insulating membrane produced by oligodendrocytes. (rupress.org)
  • We, in this study, perform a comprehensive analysis of exonic DNMs in the protein-coding regions as rare variants potentially related to BD. (nature.com)
  • Molecular modeling predicts that these variants affect binding of sphingosine-1-phosphate (p.Arg108Pro) and G protein docking (p.Tyr140Cys). (omicsdi.org)
  • The main splice variant is composed of three exons that code for a 232 amino acid protein, clarin 1. (molvis.org)
  • Reduced nitrogen enters the human body as dietary free amino acids, protein, and the ammonia produced by intestinal tract bacteria. (medmuv.com)
  • Regions with significant homology [ ( PUBMED:7559667 ) ] to the C2-domain have been found in many proteins. (embl.de)
  • biological monophosphate-activated myosin recruits( FATPs) are a domain of rafts which are synaptic spontaneous concentration into numbers when subject. (familie-vos.de)
  • Taxonomy and function of C1 protein kinase C homology domains. (embl.de)
  • KH-type splicing regulatory protein (KSRP) contains four K homology RNA-binding domains. (novusbio.com)
  • A family of protein-deglutamylating enzymes associated with neurodegeneration. (sysy.com)
  • The main ion channel is composed of a water pore that runs through the entire length of the protein. (proteopedia.org)
  • The number and location of focal spots relative to nerve terminals, and their remarkable ring-shaped structure, which is reminiscent of synaptic dense bodies, are consistent with Gem/Ca v 1.3a channels clustering at HC ribbon synapses. (jneurosci.org)
  • These repeats can drive at least three consistent unliganded containing proteins processing on which organizations they are. (evakoch.com)
  • Long-term memory consolidation: The role of RNA-binding proteins with prion-like domains. (tcd.ie)
  • In this Commentary, I review evidence in favor of the idea that partitioning of TMDs into bilayer domains that are endowed with distinct physico-chemical properties plays a pivotal role in the transport of membrane proteins within the early secretory pathway. (biologists.com)
  • A protective layer of mucopolysaccharides called mucus is secreted by corals, and it has been characterized as containing sulfated glycoproteins similar to chondroitin sulfate, [ 44 ] which play an important role in controlling pH and the transepithelial movement of electrolytes and water, just as is the case in vertebrate mucosa. (transcendingsquare.com)
  • This great importance necessitates a better understanding of key biological processes of crustaceans in order to address key bottlenecks in the fishery and aquaculture industries to enable it to meet the ever-growing demand in quality protein [ 6 ], as well as to devise species-specific treatments for invasive species. (biomedcentral.com)