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  • Signaling
  • The discovery of phosphatase micro-exclusion from signaling elements in immunological synapses and innate phagocytic synapses define a common functional unit at a common sub-micron scale across synapse types. (jci.org)
  • More restrained signaling may promote a longer-lived junction than can then be used to process action potentials into chemical synapse and compute one output from many inputs. (jci.org)
  • Synapses have distinct organization and are composed of T cell receptors interacting with major histocompatibility complex-peptide entities surrounded by various potentiating coreceptors and signaling molecules that migrate into the synapse through cytoskeleton-dependent processes. (sciencemag.org)
  • Greek
  • The word "synapse" - from the Greek synapsis ( συνάψις ), meaning "conjunction", in turn from συνάπτεὶν ( συν ("together") and ἅπτειν ("to fasten")) - was introduced in 1897 by the English neurophysiologist Charles Sherrington in Michael Foster 's Textbook of Physiology . (wikipedia.org)
  • conjunction
  • The new Synapse SSDs are optimized for caching applications and leverages Dataplex cache software to dynamically manage the Synapse SSD in conjunction with standard hard disk drives (HDDs), to provide users with SSD-level performance across the entire capacity of the HDD, the vendor said. (digitimes.com)
  • cell
  • Cell-cell communication systems in the immune and nervous systems share several features, which has led to the adoption of the common term "synapse" to describe the close cell-cell contacts in each. (jci.org)
  • Herein we refer to data from phagocytic, T cell, B cell, and NK cell synapses as specific subtypes of immunological synapses. (jci.org)
  • D ) Micrograph of a T cell synapse. (jci.org)
  • elements
  • Sherrington struggled to find a good term that emphasized a union between two separate elements, and the actual term "synapse" was suggested by the English classical scholar Arthur Woollgar Verrall , a friend of Michael Foster . (wikipedia.org)
  • Illustration of the major elements in a prototypical synapse . (mcgill.ca)
  • simple
  • Scientists just built a memristor that mimics a synapse so closely, we could do simple classical conditioning on it. (extremetech.com)
  • Previous
  • A computer model, to a significant extent co-developed by him, simulated the rewiring of neurons and, in doing so, did not restrict itself - as previous models - to the amplification or weakening of existing synapses, but instead created new links. (tu-darmstadt.de)
  • Contrary to previous assumptions, dopamine helps both strengthen and weaken synapses made by cortical cells onto cells of the subcortical striatum. (sciencemag.org)
  • term
  • In this study, Bear's team also used the phosphorylation of hippocampal glutamate receptors to show that LTP had occurred, but not its counterpart, long-term depression - another learning-induced process that involves the weakening, rather than strengthening of synapses. (the-scientist.com)
  • Long-term potentiation (LTP) and long-term depression (LTD) at these synapses are thought to be dependent on D 1 and D 2 dopamine receptors, respectively. (sciencemag.org)
  • forms
  • These proteins are also required during synaptogenesis to ensure that the synapse forms properly. (els.net)
  • available
  • OCZ Synapse SSDs are available now in 2.5-inch SATA3 64GB and 128GB configurations throughout the company's global channel. (digitimes.com)