Symptoms in cold urticaria. Medical search. Frequent questions

Life-threatening risks include suffocation resulting from swollen tissue (pharyngeal angioedema) induced by cold foods or beverages, drowning after shock from swimming in cold water, and anaphylactic shock. (wikipedia.org)
In general, patients with urticaria do not require further inpatient care unless their urticaria is severe and does not respond to antihistamine therapy or unless they progress to laryngeal angioedema and/or anaphylactic shock or have comorbidities that necessitate inpatient therapy. (medscape.com)
2024). Urticaria & angioedema. (mhmedical.com)
Urticaria involves hives, angioedema, or both. (mhmedical.com)
Angioedema is no more likely than urticaria to be associated with systemic complications, such as laryngeal edema or hypotension. (mhmedical.com)
Vibratory urticaria is a condition in which exposing the skin to vibration, repetitive stretching, or friction results in allergy symptoms such as hives (urticaria), swelling (angioedema), redness (erythema), and itching (pruritus) in the affected area. (medlineplus.gov)
Dicha estrategia consistió en intubación con fibroscopio por parte del anestesiólogo, o bien traqueostomía quirúrgica practicada por el equipo de cirugía, realizándose ambas técnicas con el paciente despierto y ventilación espontánea.El objetivo de este informe de caso es alertar de que el angioedema es una situación potencialmente mortal. (bvsalud.org)
We discuss similarities and differences in symptoms, diagnosis and treatment between these causes of angioedema. (bvsalud.org)

Chronic urticaria is further divided into chronic spontaneous urticaria and chronic inducible urticaria. (mhmedical.com)
Some patients with chronic spontaneous urticaria demonstrate autoantibodies directed against mast cell IgE receptors. (mhmedical.com)
The cause of chronic spontaneous urticaria is often not found. (mhmedical.com)
In total, 22 scientific abstracts are being presented at the EADV 2022 Congress discussing Dupixent in atopic dermatitis in patients as young as six months, and its investigational use in chronic spontaneous urticaria and bullous pemphigoid, in addition to prurigo nodularis. (pipelinereview.com)
The potential uses of Dupixent in prurigo nodularis, chronic spontaneous urticaria and bullous pemphigoid are currently under clinical development, and the safety and efficacy have not been fully evaluated by any regulatory authority. (pipelinereview.com)
Acute hives (sometimes called acute urticaria or acute spontaneous urticaria) are hives that appear suddenly, and then fade away on their own. (eyebulb.com)
The US Food and Drug Administration (FDA) has issued a complete response letter regarding the application for approval of dupilumab for the treatment of chronic spontaneous urticaria (CSU) in people aged 12 years and older, according to the manufacturers, Regeneron and Sanofi. (medscape.com)

Acute inflammatory dermatosis conditions include erythema multiforme (EM), pruritus (urticaria), and eczema ( TABLE 1 ). (uspharmacist.com)

The lesions of IgE-mediated urticaria usually last less than 24 hours and are often migratory and leave no residual skin abnormalities. (medscape.com)
The attacks usually occur 1-2 hours following exposures to cold and last less than 24 hours. (lu.se)
Individual lesions in true urticaria last less than 24 hours and often only 2-4 hours. (mhmedical.com)

Paroxysmal cold hemoglobinuria (PCH) has the distinction of being the first, albeit rarest, type of autoimmune hemolytic anemia (AIHA) to be identified. (medscape.com)
Paroxysmal cold hemoglobinuria shares similar antibody thermal activity range as cold hemagglutinin disease (CHD), the more common cold variant of autoimmune hemolytic anemia. (medscape.com)

The wheals of cholinergic urticaria are 2-3 mm in diameter with a large surrounding red flare. (mhmedical.com)

Cold urticaria may be divided into the following types: Primary cold contact urticaria is a cutaneous condition characterized by wheals, and occurs in rainy, windy weather, and after swimming in cold water and after contact with cold objects, including ice cubes. (wikipedia.org)
Secondary cold contact urticaria is a cutaneous condition characterized by wheals, due to serum abnormalities such as cryoglobulinemia or cryofibrinogenemia are extremely rare, and are then associated with other manifestations such as Raynaud's phenomenon or purpura. (wikipedia.org)
However, it should be noted that in some cases, urticaria occurs in response to contact with cold and, therefore, by cooling the area we would only exacerbate the problem.The truth is that contact urticaria never benefits from hot, quite the opposite, you should avoid applying heat over the affected areas, in order not to worsen urticaria symptoms. (botanical-online.com)
Cold contact urticaria (CCU) features the itchy wheal and flare responses following the release of histamine and other pro-inflammatory mediators after exposure to cold. (emedinexus.com)

Acute IgE-mediated urticaria is the most benign form of anaphylaxis . (medscape.com)
Therefore, the clinician must rule out these more severe syndromes of anaphylaxis in patients presenting with urticaria. (medscape.com)
You may hate the cold, but for people suffering from "cold urticaria", it may cause anaphylaxis requiring a jab from their epinephrine auto-injector and a trip to the ER. (snacksafely.com)
In 20% of those that suffer from cold urticaria, the reaction can rise to the level of anaphylaxis, requiring prompt administration of epinephrine and a hospital visit. (snacksafely.com)
Swimming alone and in combination with the wind were significantly the most reported triggers in patients with cold-induced anaphylaxis (ColdA) when compared with patients with ColdU and with nonanaphylactic symptoms (70.0% versus 28.9% [p = 0.022], and 50.0% versus 4.1% [p (erdogan.edu.tr)
However, if aucte urticaria is a prelude to the further development of anaphylaxis, the most severe form of allergic reaction, the urticaria must be managed as quickly as possible. (eyebulb.com)
Symptoms of anaphylaxis include breathing difficulties, loss of consciousness, and a drop in blood pressure. (cdc.gov)

Usually, however, the experienced clinician is able to distinguish these other diseases from urticaria because of the latter's distinctive appearance (see the images below), because it is intensely pruritic, and because it blanches completely with pressure. (medscape.com)
There is wide evidence that some supplements are particularly interesting in the treatment of allergic diseases such as allergic urticaria. (botanical-online.com)
By attaching to interleukin‑1 beta, canakinumab blocks its activity, helping to reduce inflammation thereby relieving the symptoms of the diseases. (europa.eu)
True urticaria should be differentiated from diseases that present with similar lesions that are not true urticaria (eg, adult-onset Still disease, urticarial vasculitis, and cryopyrin-associated periodic syndromes). (mhmedical.com)
The cold season means a lot of health problems, it not only causes common colds, coughs and flu but also caused other diseases. (healthbanana.com)
Let's find the causes and treatments for common diseases during the cold season. (healthbanana.com)
Diseases Treatments Dictionary This is complete solution to read all diseases treatments Which covers Prevention, Causes, Symptoms, Medical Terms, Drugs, Prescription, Natural Remedies with cures and Treatments. (diseasesdic.com)
In addition to CSU, dupilumab is being studied for treatment of chronic inducible urticaria triggered by cold (LIBERTY-CINDU CUrIADS program) in an ongoing phase 3 trial and for treatment of a broad range of other diseases driven by type 2 inflammation. (medscape.com)
A group of rare autosomal dominant diseases, commonly characterized by atypical URTICARIA (hives) with systemic symptoms that develop into end-organ damage. (bvsalud.org)

Omega-3 Fatty Acids are found in such foods as cold-water fish (think salmon), and walnuts, but since this is a blog devoted to food allergy sufferers, I prefer to recommend you get your Omega-3s from less allergenic sources, such as hemp seeds, flax seed oil, canola oil, and grass-fed meat. (cybelepascal.com)
Urticaria occurring at the time of antibiotic use is often due to the underlying infection rather than an allergy to the antibiotic. (rch.org.au)
Cold urticaria: an allergy that isn't an allergy. (ecarf.org)
It belongs to a class of disorders called physical urticarias in which allergy symptoms are brought on by direct exposure to factors such as pressure, heat, cold, or sunlight. (medlineplus.gov)
Researchers suggest that once the subunits are disconnected, the beta subunit signals the mast cells to react and produce the allergy symptoms in the skin that occur in vibratory urticaria. (medlineplus.gov)
In comparing lifelong asthmatics with late-onset, the former more commonly have other allergic symptoms, such as hay fever or food allergy. (allergy-associates.com)
One common physical allergy is cold urticaria (hives). (allergy-associates.com)
It is also used to relieve symptoms of allergy due to dust and pet allergies. (pharmeasy.in)
Notril Tablet works by blocking the action of histamine and reliev es allergy symptoms. (pharmeasy.in)
A 23-year-old woman could be killed by the cold air or a chilled drink because she suffers from a rare allergy. (worldmedicinefoundation.com)
Miss Fisher experiences red, itchy hives and her throat closes up because of her allergy to the cold, which could trigger anaphylactic shock. (worldmedicinefoundation.com)
Max Fisher, 23, could be killed by the cold due to a rare allergy called cold urticaria. (worldmedicinefoundation.com)
Her symptoms were mistaken for a pollen allergy for the several weeks, and she claims even now some medical professionals don't understand her condition. (worldmedicinefoundation.com)
Initially doctors thought it was a pollen allergy but further tests revealed it was urticaria. (worldmedicinefoundation.com)

There are many causes for cold hives, most are idiopathic (meaning they have no known cause). (wikipedia.org)
A study in 84 patients with childhood Still's disease (also known as systemic juvenile idiopathic arthritis, SJIA) found that Ilaris was more effective than placebo at reducing symptoms of arthritis: around 84% of patients who received Ilaris achieved the required reduction in symptoms, compared with about 10% of patients who received placebo. (europa.eu)
This photo shows a positive ice cube test in a patient with idiopathic cold-induced urticaria. (msdmanuals.com)

Anyone can develop cold urticaria, however, people are more at risk if they are young, have recently had an infection, have an underlying condition or have inherited certain genetic traits. (worldmedicinefoundation.com)

In many cases of urticaria it cures by its own. (diseasesdic.com)

The fatigue, the weight gain, the hives or urticaria, and the fact that my body temperature had run cold my entire life were all common thyroid symptoms in women. (nutritionaltherapy.com)
Hives (or urticaria) is a skin rash caused by various non-allergic and allergic causes. (makariwellness.com)

As one of the symptoms of cold urticaria, itchy hives on the affected skin are common. (healthbanana.com)
When exposure to cold temperatures causes itchy hives to appear on the skin, this is referred to as cold urticaria. (charite.de)

This photo shows solar urticaria in a woman who had been wearing a tank top. (msdmanuals.com)

Urticaria results from the release of histamine, bradykinin, kallikrein, and other vasoactive substances from mast cells and basophils in the superficial dermis, resulting in intradermal edema caused by capillary and venous vasodilation and occasionally caused by leukocyte infiltration. (msdmanuals.com)

However, unlike cold hemagglutinin disease in which the IgM-complement interaction results in the cells' removal (via extravascular phagocytosis), paroxysmal cold hemoglobinuria occurs upon completion of complement lysis within the vascular circulation. (medscape.com)
Cold urticaria occurs most frequently in young adults. (womenshealthblog.org)
A skin reaction called cold urticaria typically occurs minutes after being exposed to the cold. (healthbanana.com)

Urticaria pigmentosa may manifest as reddish plaque-like lesions on the skin. (msdmanuals.com)
The infant shown here has profuse papulonodular and plaque lesions of urticaria pigmentosa. (msdmanuals.com)

Cold Urticaria - Also known as hives. (sportsinjuryclinic.net)
Urticaria, also known as hives, is estimated to affect around one in five people at some point in their lives, according to the NHS. (worldmedicinefoundation.com)

This condition was first described in 1854 as an abrupt onset of systemic manifestations, including severe anemia and hemoglobinuria, occurring upon exposure to cold temperatures and resulting from massive intravascular hemolysis. (medscape.com)
In these people, the immune system response to cold temperatures is due to a genetic defect which, in addition to a skin rash, will cause signs of systemic inflammation, including fever and joint pain. (charite.de)

This disorder, or perhaps two disorders with the same clinical manifestations, can be inherited (familial cold urticaria) or acquired (primary acquired cold urticaria). (wikipedia.org)
Scientists from the USA National Institutes of Health have identified a genetic mutation in three unrelated families that causes a rare immune disorder characterized by excessive and impaired immune function: immune deficiency, autoimmunity, inflammatory skin disorders and cold-induced hives (cold urticaria). (wikipedia.org)
The causes can be similar to those of acute urticaria but can also include your immune system, chronic infections, hormonal disorders, and tumors. (webmd.com)
But cold-induced urticaria makes up about one to three per cent of all urticaria cases, according to the National Organisation of Rare Disorders. (worldmedicinefoundation.com)

Discover the symptoms and treatment for cold urticaria, an allergic reaction to cold temperatures. (americanstories5.com)

A fourth study in 181 patients with other periodic fever syndromes found that Ilaris was more effective than placebo in achieving a response (symptoms resolved with no new flare ups). (europa.eu)

Hives due to physical causes (such as pressure, cold, or sun exposure) are called physical hives. (kidshealth.org)
To check for physical hives, a doctor may put ice on your skin to see how it reacts to cold or place a sandbag or other heavy object on your thighs to see if the pressure will cause hives. (kidshealth.org)
Urticaria is usually linked to other causes: In one in five people with urticaria, the condition is triggered by physical stimuli such as light, friction, vibration, pressure, and also cold (Wütherich 2006). (ecarf.org)
exposure to certain types of physical stimuli like pressure (like scratching yourself), cold, and heat can cause hives. (acaai.org)
Doctors refer to this type of skin condition, which accounts for nearly 20 percent of hives as physical urticaria (the medical term for hives). (acaai.org)
Physical urticarias have been estimated to occur in up to 5 per 1,000 people. (medlineplus.gov)
Abajian M, Mlynek A, Maurer M. Physical urticaria. (medlineplus.gov)
Acute urticaria or acute onset of physical urticaria itself rarely results in a life-threatening condition. (eyebulb.com)
Because there are no definitive diagnostic tests for urticaria, evaluation largely relies on history and physical examination. (msdmanuals.com)

Dry, fissured, pruritic eczema is frequently the result of excessive washing and very low humidity in cold climates. (medscape.com)
There are a few things you can do to help relieve the symptoms of eczema during the winter months. (womenshealthblog.org)

The study's findings could help researchers discover the causes of currently unexplained cases: people with hereditary cold urticaria of unknown origin, in whom conventional drugs such as antihistamines are ineffective, can undergo genetic testing for FACAS. (charite.de)

Americans spend billions of dollars annually on antihistamines to treat symptoms of allergies. (cybelepascal.com)

Familial cold urticaria (also properly known as familial cold autoinflammatory syndrome, FCAS) is an autosomal dominant condition characterized by rash, conjunctivitis, fever/chills and arthralgias elicited by exposure to cold - sometimes temperatures below 22 °C (72 °F). It has been mapped to CIAS1 and is a slightly milder member of the disease family including Muckle-Wells syndrome and NOMID. (wikipedia.org)
severe forms of familial cold auto-inflammatory syndrome (FCAS) / familial cold urticaria (FCU) presenting with signs and symptoms beyond cold-induced urticarial skin rash. (europa.eu)
Some people develop a skin rash when exposed to cold temperatures. (ecarf.org)
This is why the rash is called nettle rash, or urticaria . (ecarf.org)
worse in warmth, better in cold, rash before menses. (hpathy.com)
Cold Erythema - A rash, characterised by redness and itching, caused by exposure to cold. (sportsinjuryclinic.net)
Symptoms usually start in early adulthood with the most common symptom being a red, itchy rash that appears on the skin when it is exposed to cold weather or water. (snacksafely.com)
The symptoms are mostly an urticarial rash, big swollen, hot and very itchy. (worldmedicinefoundation.com)
Skin rash combined with head and joint pain: these are the symptoms which patients with familial (hereditary) cold urticaria develop when exposed to temperatures below 15 °C. Researchers from Charité - Universitätsmedizin Berlin have discovered a new, previously unknown form of this inflammatory skin disorder. (charite.de)

For chronic or recurrent urticaria, basic laboratory studies should include a complete blood count (CBC), erythrocyte sedimentation rate (ESR), thyroid-stimulating hormone (TSH) level, and an antinuclear antibody (ANA) test to look for possible causes of the urticaria. (medscape.com)
Exposure can be reduced with careful instruction, but occult exposures may produce chronic or recurrent symptoms. (medscape.com)

Continue monitoring and providing support to the vaccinee who has fainted until signs and symptoms have stabilized. (canada.ca)
MCAS is a recently described collection of signs and symptoms involving several different organ systems, that, as with ME/CFS itself, do not typically cause abnormalities in routine laboratory or radiologic testing. (medscape.com)

Oenothera biennis ) Evening primrose has got antihistamine properties that could be used in the treatment of urticaria, helping reduce the appearance of the characteristic "wheals" and reducing the itching. (botanical-online.com)
If you still want to expose yourself to lower temperatures, as you would do when going for a cooling swim on a hot summer's day, the latest European urticaria guideline (Zuberbier 2018) recommends that you take an antihistamine two hours before you jump in. (ecarf.org)
Use an antihistamine (over-the-counter) before coming into contact with the cold. (healthbanana.com)

Diagnosis is typically obtained by an allergist or other licensed practitioner performing a cold test. (wikipedia.org)
Usually a thorough history of how symptoms began and the triggers can indicate and point to the diagnosis. (bahrainthismonth.com)
ME/CFS is a descriptive diagnosis of a bunch of symptoms, but it says nothing about what's causing the symptoms, which is probably part of the reason it's so hard for it to get recognition. (medscape.com)

The hives are a histamine reaction in response to cold stimuli, including a drastic drop in temperature, cold air, and cold water. (wikipedia.org)
A significant decrease in the microdialysis levels of histamine, IL-6 and IL-8, 1 to 3 hours after the cold challenge following up-dosing with 80 mg bilastine. (emedinexus.com)
Allergic symptoms appear due to the production of a chemical in the body, namely histamine. (pharmeasy.in)

The etiologies of both acute and chronic urticaria are numerous. (medscape.com)
Urticaria is divided into acute and chronic forms. (mhmedical.com)

Call your health care provider if your symptoms worsen or don't improve with at-home care. (bannerhealth.com)

In addition, sensitivities to cold and heat, and to contaminants in household water supplies have been associated with symptoms ranging from urticaria to severe respiratory distress. (ehcd.com)
Symptoms can wax and wane over years and range from mild to severe/debilitating. (medscape.com)

Although most cases of paroxysmal cold hemoglobinuria occur as an acute event in children younger than 5 years, recurrent episodes have been reported. (medscape.com)
6, 7, 8, 9, 10] Furthermore, because the D-L antibody does not necessarily occur with a specified cold exposure event, nor is it recurrent in nature, an alternative classification of Donath-Landsteiner hemolytic anemia was proposed. (medscape.com)
When symptoms are recurrent, and affect the quality of life, one must consult with a doctor. (bahrainthismonth.com)

The most common causes of acute urticaria are foods, upper respiratory infections, and medications. (mhmedical.com)
There is a close temporal relationship observed between viral or bacterial agents and the development of paroxysmal cold hemoglobinuria within 2-3 weeks of upper respiratory or gastrointestinal symptoms. (medscape.com)

Dermatology referral is mandatory if vasculitic urticaria is suspected. (medscape.com)
Franziska Rueff, senior physician at the Clinic and Polyclinic of Dermatology and Allergology at Ludwig-Maximilians-Universität München, estimates that around 50,000 people in Germany have cold urticaria (BR Television, 2020). (ecarf.org)
Researchers led by PD Dr. Karoline Krause of the Department of Dermatology, Venereology and Allergology on Campus Charité Mitte have now discovered a new form of cold urticaria which is caused by a previously unknown mutation in the 'Factor 12' gene. (charite.de)
In a poster presented at the European Academy of Dermatology and Venereology (EADV) Congress, which was held in October in Berlin, researchers found that patients with CSU who were treated with dupilumab experienced a significant drop in urticaria and an improvement in general and disease-specific health-related quality of life at week 24. (medscape.com)

In case of frequent episodes of urticaria, you should consult with your doctor the advisability of using any of them. (botanical-online.com)
Currently, episodes of paroxysmal cold hemoglobinuria usually occur after a viral infection and are abrupt in onset and transitory. (medscape.com)
Dear Dr. K.: In cold months I get episodes when my hands get red, swell, itch and burn for days at a time. (allergy-associates.com)

Therefore, if cold urticaria is suspected, the threshold temperature for each patient must be individually determined - for example, by touching the skin with containers that are filled with liquids of different temperatures, or by immersing the arm in cold water. (ecarf.org)
It can be used to quickly determine the threshold temperatures for cold and heat urticaria (Magerl, 2015). (ecarf.org)
When large parts of the body are exposed to cold temperatures - for example, when jumping into cold water - the blood circulation of the organs can be restricted. (ecarf.org)
Ben-Shoshan recognized her symptoms: she was experiencing a rare reaction to cold temperatures otherwise known as cold urticaria . (snacksafely.com)
Cold urticaria is an abnormal reaction of the skin to cold temperatures. (womenshealthblog.org)
Ultimately, the best way to avoid this is to avoid extremely cold temperatures. (womenshealthblog.org)
Raynaud's is a common skin disease in the cold season that can cause your fingers and toes to become numb and chilly in response to extremely cold temperatures. (healthbanana.com)
Cold urticaria is a skin reaction that causes it to break out in hives when exposed to low temperatures. (worldmedicinefoundation.com)
Cold urticaria often goes away on its own but can be treated via antihistamines and avoiding temperatures below 39°F (4°C). (worldmedicinefoundation.com)

More information about urticaria and its natural treatment . (botanical-online.com)
Three studies involving 220 adults and children 2 years and older showed that Illaris was effective at reducing relapses of CAPS symptoms after a 24-week treatment period. (europa.eu)
Cold therapy or Cryotherapy is a popular treatment method for sports injuries. (sportsinjuryclinic.net)
Ninety-five percent of patients responded to treatment, with 60% becoming symptom-free at this dose. (emedinexus.com)
Increased efficacy of bilastine with fourfold up-dosing comes without sedation and supports the urticaria treatment guidelines. (emedinexus.com)
Their symptoms also failed to respond to antihistamines, which are normally an effective treatment for cold urticaria. (charite.de)
If symptoms are mild treatment is not needed. (diseasesdic.com)
Study B evaluated dupilumab in 108 patients (aged 12 to 80 years) with CSU who had symptoms despite standard-of-care treatment and who were intolerant of omalizumab or had experienced an incomplete response to it. (medscape.com)

Chronic urticaria often lasts months to years, eventually resolving without a cause being found. (msdmanuals.com)

The name proposed for this new hereditary disorder is 'Factor XII-associated cold autoinflammatory syndrome', or FACAS. (charite.de)

Basically the exposure to cold is assumed to generate an auto-allergen, so a substance that your immune system reacts to. (snacksafely.com)

Cold urticaria (essentially meaning cold hives) is a disorder in which large red welts called hives (urticaria) form on the skin after exposure to a cold stimulus. (wikipedia.org)

Symptoms usually do not occur until early adulthood. (ecarf.org)

The prevalence rate for chronic urticaria has been estimated as 1-5 per 1,000. (diseasesdic.com)

SALT LAKE CITY, UT - Mast cell activation syndrome (MCAS) may be an overlooked yet potentially treatable contributor to the symptoms of chronic fatigue syndrome/ myalgic encephalomyelitis (ME/CFS), say physicians who specialize in ME/CFS and its manifestations. (medscape.com)

Results: A total of 83 children with ColdU were included, 54.2% were girls, and the mean age of symptom onset was 8.8 years. (erdogan.edu.tr)
Onset of symptoms began approximately 3-20 minutes after ingestion, and all three persons were transported by ambulance to a local emergency department (ED). This report summarizes the investigation of these cases by the San Diego Department of Environmental Health (SDEH) and the Food and Drug Administration (FDA). (cdc.gov)

Paroxysmal cold hemoglobinuria is a rare disorder, with a prevalence rate that is largely unknown within the US population or worldwide. (medscape.com)

Vibratory urticaria can be caused by a mutation in the ADGRE2 gene. (medlineplus.gov)
Some people with vibratory urticaria do not have a mutation in the ADGRE2 gene. (medlineplus.gov)

Urticaria affects around 20% of people at some time during their lives. (makariwellness.com)

Reflex cold urticaria is a cutaneous condition in which generalized cooling of the body induces widespread welting. (wikipedia.org)
When the body is exposed to the cold in individuals affected by the condition, hives appear and the skin in the affected area typically becomes itchy. (wikipedia.org)
The condition is called "cold urticaria. (delilahdevlin.com)
A contraindication to cold therapy is an injury or condition that would make applying cold therapy to a sports injury dangerous. (sportsinjuryclinic.net)
Chronic urticaria (CU) is a disturbing allergic condition of the skin. (eyebulb.com)

There are various triggers that can cause urticaria. (ecarf.org)

Urticaria appears as raised, well-circumscribed areas of erythema and edema, often with central pallor, that involve the dermis and epidermis and are usually very pruritic. (medscape.com)

Diseases7

Chemicals and Drugs4

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes1

Health Care1

Angioedema8

Spontaneous urticaria7

Pruritus1

Last less than 24 hours3

Autoimmune2

Cholinergic1

Contact urticaria4

Anaphylaxis7

Diseases9

Allergy14

Idiopathic3

Develop cold urticaria1

Cases of urticaria1

Hives or urticaria2

Itchy hives2

Solar urticaria1

Release of histamine1

Occurs3

Lesions2

Known as hives2

Systemic2

Disorders4

Allergic reaction1

Syndromes1

Physical9

Eczema2

Genetic1

Allergies1

Rash9

Chronic or recurrent2

Signs and symptoms2

Antihistamine3

Diagnosis3

Histamine3

Acute and chronic2

Worsen1

Severe2

Recurrent3

Respiratory2

Dermatology4

Episodes3

Temperatures9

Treatment8

Lasts1

Autoinflammatory syndrome1

Exposure to cold1

Welts1

Early adulthood1

1,0001

Mast1

Onset2

Prevalence rate1

Mutation2

Affects1

Condition5

Triggers1

Pallor1