AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesHealth Care
Endocrine System DiseasesHypogonadismMultiple Endocrine Neoplasia Type 1Multiple Endocrine NeoplasiaMultiple Endocrine Neoplasia Type 2aMultiple Endocrine Neoplasia Type 2bProto-Oncogene Proteins c-retCarcinoma, MedullaryPheochromocytomaGastrinomaAdrenal Gland NeoplasmsParathyroid NeoplasmsEndocrine GlandsHyperparathyroidism, PrimaryEndocrine SystemThyroid NeoplasmsZollinger-Ellison SyndromeEndocrine Gland NeoplasmsGerm-Line MutationHyperparathyroidismPituitary NeoplasmsInsulinomaProto-Oncogene ProteinsEndocrine DisruptorsAdenoma, Islet CellPedigreeReceptor Protein-Tyrosine KinasesPancreatic NeoplasmsNeuromaChromosomes, Human, Pair 11ThyroidectomyAdenomaNeuroendocrine TumorsCarcinoid TumorAngiofibromaParathyroidectomyBone Demineralization, PathologicMetanephrineGlucagonomaCalcitoninMutationGenetic TestingDuodenal NeoplasmsHirschsprung DiseaseParathyroid GlandsDrosophila Proteinsvon Hippel-Lindau DiseaseGanglioneuromaSyndromeProlactinomaAbnormalities, MultipleParagangliomaPhenotype
NeoplasiaTumorsDisordersCongenitalSyndromeClinicalDiagnosisPituitary glandPsychiatricMEN1Glands can causePancreaticSignsDisorderSkeletalGeneticHypoparathyroidismTumorBiochemicalMalignantDevelopmentalDiagnosticDiseasesCognitiveHypothyroidismMEDULLARYBehavioralHaematologicalIschemic strokeBlood vesselsSevereBody'sTypeAdrenalEndocrinologyConditionsOrganHypertensionPatientsComplicationsVascularIncludeAcute COVID-19
Neoplasia27
Tumors7
  • However, nonfunctioning pancreatic endocrine tumors are the most common enteropancreatic neuroendocrine tumor. (medscape.com)
  • Tumors causing symptoms are surgically removed when possible. (merckmanuals.com)
  • Tumors are removed surgically if they cause symptoms or for suspected malignancy based on size criteria. (merckmanuals.com)
  • Familial medullary thyroid carcinoma (FMTC): patients with this condition have an 80% chance of developing medullary thyroid cancer, but less than a 5% chance of developing other endocrine tumors. (endocrinology-centers.com)
  • If such an MEN1 variant cannot be identified, the definition of MEN1 allows the diagnosis to be made clinically: as the occurrence of two or more primary MEN1 tumor types (parathyroid, enteropancreatic endocrine, and pituitary tumors), or in family members of a patient with a clinical diagnosis of MEN1, the occurrence of one of the MEN1-associated tumors. (medilib.ir)
  • Multiple parathyroid tumors causing primary hyperparathyroidism are the most common component of MEN1, occurring in the large majority of patients by age 50 years, and is the initial manifestation of the disorder in most patients. (medilib.ir)
  • Biochemical signs and severity of symptoms of primary hyperparathyroidism (pHPT) differ among patients, and little is known of any coupling of clinical characteristics of nonfamilial pHPT to genetic abnormalities in the parathyroid tumors. (lu.se)
Disorders5
  • They are accompanied with a range of metabolic and endocrine abnormalities involved in the pathophysiology of pancreatic cancer, including fatty acid metabolism disorder, insulin resistance, inflammatory processes, and disorders in hormonal changes and pancreatic steatosis. (frontiersin.org)
  • A further three patients had a milder PS phenotype before progression to Kearns-Sayre syndrome (KSS) with neurological and endocrine disorders, including diabetes, osteoporosis and hypoparathyroidism. (medwirenews.com)
  • These children also experienced endocrine disorders, such as diabetes, mitochondrial diabetes, hypoparathyroidism and osteopenia or osteoporosis, as well as a range of neuromuscular symptoms associated with sensory neural hearing loss, retinopathy, cardiac rhythm abnormalities and proximal tubulopathy. (medwirenews.com)
  • Another significant way by which microbes can affect the brain is by activation of the immune system, as about 80 percent of the body's immune cells reside in the gut, and immune abnormalities contribute to several neurological disorders. (kiyalongevity.com)
  • For use in certain endocrine and non-endocrine disorders responsive to corticosteroid therapy. (who.int)
Congenital4
  • It is characterized by a congenital facial birthmark and neurological abnormalities. (sturge-weber.org)
  • Sufferers generally present with EPI, multiple congenital anomalies, hypothyroidism and developmental hold off. (healthandwellnesssource.org)
  • Milder JBS phenotypes have already been described, hence the lack of multiple congenital anomalies or mental retardation will not eliminate this symptoms.78, 79 Pearson Symptoms That is a rare multisystem disorder due to defects within the oxidative phosphorylation because of sporadic mutations within the mitochondrial DNA80. (healthandwellnesssource.org)
  • Background: Cardiofaciocutaneous (CFC) syndrome is a rare disorder characterised by multiple abnormalities including congenital heart disease, craniofacial dysmorphology, ectodermal abnormalities, developmental delay, and epilepsy. (endocrine-abstracts.org)
Syndrome6
  • 4] Signs and symptoms included reduced visual acuity, optic atrophy, visual field defects, and a chiasmatic syndrome. (medscape.com)
  • Gut And Psychology Syndrome addresses the root of all of these symptoms and diseases. (gaps.me)
  • Multiple other body organs are rarely affected in Sturge-Weber syndrome. (sturge-weber.org)
  • [ 4 ] When fibrous dysplasia occurs in the setting of other extraskeletal abnormalities, skin pigmentation, and endocrine dysfunction, the resulting syndrome is named McCune-Albright syndrome . (medscape.com)
  • [ 6 ] Rarely, it can also be associated with solitary or multiple soft-tissue myxomas (Mazabraud syndrome). (medscape.com)
  • The use of prochlorperazine and other potential hepatotoxins should be avoided in children and adolescents whose signs and symptoms suggest Reye's syndrome. (drugs.com)
Clinical14
  • Clinical manifestations can include hypercalcemia, nephrolithiasis, and bone abnormalities (osteitis fibrosa cystica). (medscape.com)
  • 2 It has been shown that the classical intestinal clinical symptoms of malnutrition, chronic diarrhea, and nutritional deficiencies are diminishing while extraintestinal presentations are emerging. (theceliacscene.com)
  • Because of the clinical similarity between MEN 1 and MEN 4, patients with this constellation of symptoms should undergo genetic testing utilizing a panel of genes that includes both MEN1 and CDKN1B . (merckmanuals.com)
  • Patients with C10ORF2-linked adPEO may have other clinical features including proximal muscle weakness, ataxia, peripheral neuropathy, cardiomyopathy, cataracts, depression, and endocrine abnormalities (summary by Fratter et al. (nih.gov)
  • The symptoms of frontotemporal dementia fall into two clinical patterns that involve either: (1) changes in behavior, or (2) problems with language. (mentalhealthhelpcenter.com)
  • In each clinical presentation, skin symptoms are also common. (cdghub.com)
  • The VBM results demonstrated a morphological correlate of central nervous system involvement in KD, in agreement with aspects of the clinical phenotype (behavioural abnormalities, central-peripheral axonopathy) and with pathohistological findings. (nih.gov)
  • This clinical photograph shows the distinctive pigmentation in patients with endocrine abnormalities associated with fibrous dysplasia. (medscape.com)
  • When symptoms are present, swelling or obvious deformity are the most common clinical manifestations. (medscape.com)
  • The Endocrine Surgery Fellowship provides intensive training in the diagnosis and treatment of endocrine diseases, experience in a multidisciplinary approach to treatment planning and opportunities for collaborative clinical and basic science research. (massgeneral.org)
  • The second-year fellow will continue to work on the clinical research projects selected during the first year, and will be actively involved in maintaining the endocrine surgery databases and coordinating specific research projects. (massgeneral.org)
  • Though there has been a tremendous amount of research published establishing multiple pathophysiological findings in persons with autism, many major medical institutions, organizations, and providers have yet to incorporate these into clinical practice. (autismbiology.com)
  • Exacerbation of insomnia and emergence of cognitive and behavioral abnormalities were seen with Ramelteon Tablets during the clinical development program. (nih.gov)
  • We detect emerging variants of concern up to 14 days earlier in wastewater samples, and identify multiple instances of virus spread not captured by clinical genomic surveillance. (cdc.gov)
Diagnosis5
  • Because symptoms resemble a variety of life-threatening conditions, differential diagnosis is necessary. (wikipedia.org)
  • Due to a lack of diagnostic biomarkers and early-stage symptoms, diagnosis often occurs at advanced and invasive stages. (frontiersin.org)
  • During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. (psychiatrist.com)
  • Using microsatellite analysis for loss of heterozygosity (LOH) at 11q13 and DNA sequencing of coding exons, the MEN1 gene was studied in 49 parathyroid lesions of patients with divergent symptoms, operative findings, histopathological diagnosis, and biochemical signs of nonfamilial pHPT. (lu.se)
  • Early and accurate diagnosis is important in deciding appropriate care strategies, even if the patient is not exhibiting symptoms. (cdc.gov)
Pituitary gland2
  • Symptomatic RCCs are uncommon, but cysts can enlarge and cause symptoms secondary to compression of the pituitary gland, pituitary stalk, optic chiasm, or hypothalamus. (medscape.com)
  • The pituitary gland is a pea-sized endocrine gland that sits at the base of the brain. (medscape.com)
Psychiatric3
  • The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. (psychiatrist.com)
  • Worsening of insomnia, or the emergence of new cognitive or behavioral abnormalities, may be the result of an unrecognized underlying psychiatric or physical disorder and requires further evaluation of the patient. (nih.gov)
  • Amnesia, anxiety and other neuro-psychiatric symptoms may also occur unpredictably. (nih.gov)
MEN11
  • While the condition causes symptoms that are similar to MEN1, it is the result of mutations to the CDKN1B gene, specifically the tumor-suppressing protein p27kip1. (endocrinology-centers.com)
Glands can cause1
  • Rubella (viral infection), syphilis (sexually transmitted disease during pregnancy), and abnormalities of the endocrine glands can cause cataract in newborns. (lifepositive.com)
Pancreatic3
  • Based on the expression of multiple essential genes, a complete study and various experimental models may be used to generate a prognostic signature for pancreatic cancer. (frontiersin.org)
  • Pearson Symptoms is recognized from SDS by the current presence of sideroblastic anemia, bone tissue marrow adjustments, pancreatic fibrosis instead of lipomatosis, and lack of bone tissue lesions. (healthandwellnesssource.org)
  • Other notable causes Jeune symptoms, pancreatic aplasia, pancreatic hypoplasia, isolated pancreatic enzyme deficiencies (pancreatic lipase insufficiency or PNLIP) are uncommon factors behind EPI in child years. (healthandwellnesssource.org)
Signs6
  • Symptoms and signs develop at any age. (msdmanuals.com)
  • Signs and symptoms may include trouble swallowing, difficulty breathing, hoarseness in the throat or other voice changes, a constant cough, swollen neck glands (usually non-painful), a lump around the Adam's apple in the front of your neck, neck pain that reaches up into ears. (endocrinologyga.com)
  • Signs and symptoms, including a severe decline in thinking (cognitive) skills usually appear around age 30 or 40. (mentalhealthhelpcenter.com)
  • The rising number of patients with dementia means that family physicians will have an increasingly important role in recognizing early signs and symptoms of disease, ordering appropriate tests, formally diagnosing, and, finally, treating these patients (Morris JC, 2001). (cgakit.com)
  • The extrapyramidal symptoms which can occur secondary to prochlorperazine may be confused with the central nervous system signs of an undiagnosed primary disease responsible for the vomiting, e.g. (drugs.com)
  • Explore the signs and symptoms, genetic cause, and inheritance pattern of various health conditions. (medlineplus.gov)
Disorder5
  • The phenotype of MEN 4 is similar to that of MEN 1 but lacks the cutaneous abnormalities seen in the latter disorder. (msdmanuals.com)
  • Symptoms of DOLK-CDG are highly variable and can range from only cardiac involvement (weakened and enlarged heart), only neurological involvement and vision problems (intellectual disability, autism spectrum disorder, and seizures), or in severe cases, affecting multiple body systems. (cdghub.com)
  • X linked spinobulbar muscular atrophy (Kennedy disease (KD)), which is clinically characterised mainly by neuromuscular and endocrine symptoms, has to be considered as a multisystem disorder. (nih.gov)
  • Hypocalcemia varies from a mild asymptomatic biochemical abnormality to a life-threatening disorder. (bmj.com)
  • The disorder can be monostotic (involving a single bone) or polyostotic (involving multiple bones). (medscape.com)
Skeletal2
  • Progressive external ophthalmoplegia is characterized by multiple mitochondrial DNA deletions in skeletal muscle. (nih.gov)
  • As opposed to SDS, kids with Johanson-Blizzard symptoms don't have bone tissue marrow and 1811243.0 skeletal abnormalities. (healthandwellnesssource.org)
Genetic2
  • If you have a family member with MEN but do not have symptoms yourself, you should undergo a genetic test to determine your risk. (endocrinology-centers.com)
  • The development of autism appears to be a complex interaction of multiple genetic and environmental factors . (autismbiology.com)
Hypoparathyroidism1
  • Three patients died by age 5 years following a severe haematological presentation and multiple endocrine abnormalities, including diabetes, growth failure and hypoparathyroidism. (medwirenews.com)
Tumor1
  • MEN can stimulate tumor growth on these glands, making them overproduce hormones and trigger symptoms like constipation, weight gain, and bone thinning. (endocrinology-centers.com)
Biochemical1
  • Six close relatives (parents, three siblings, maternal uncle) showed no biochemical abnormalities. (tau.ac.il)
Malignant1
  • Multiple malignant associations include abdominal colic. (sci-ed.org)
Developmental1
  • One study linked Di-ethyl phthalate to developmental abnormalities in the fetuses of exposed mothers. (naturalnews.com)
Diagnostic3
  • Many of these conditions have no established diagnostic labels and present themselves as a mixture of various symptoms: mood alterations, memory and cognitive problems, behavioural and social problems, panic attacks, anxiety, involuntary movements, tics and fits, sensory problems, etc. (gaps.me)
  • Many conditions do not fit into any diagnostic box and can present as a mixture of symptoms: digestive problems, fatigue, muscular weakness, cramps and abnormal muscle tone, pains and aches in joints and muscles, skin problems, hormonal abnormalities, neurological problems, allergies, etc. (gaps.me)
  • Treated with Bacteroides fragilis , these rodents were able to overcome their core abnormalities, including communication deficit, which is the diagnostic symptom of autism. (kiyalongevity.com)
Diseases1
  • Ample opportunity also exists for basic science research in endocrine diseases. (massgeneral.org)
Cognitive1
  • and a complete neurological exam, which includes looking for both physical and cognitive (thinking) abnormalities in the brain. (netwellness.org)
Hypothyroidism1
  • Hypothyroidism symptoms are very similar to the ones experienced by CFS sufferers. (holtorfmed.com)
MEDULLARY1
Behavioral1
Haematological1
  • The six children with PS were aged a median of 4.1 years and had experienced haematological symptoms by age 10 months. (medwirenews.com)
Ischemic stroke1
  • The clinician should first rule out conditions with similar symptoms, such as subarachnoid hemorrhage, ischemic stroke, pituitary apoplexy, cerebral artery dissection, meningitis, and spontaneous cerebrospinal fluid leak. (wikipedia.org)
Blood vessels2
  • Symptoms are thought to arise from transient abnormalities in the blood vessels of the brain. (wikipedia.org)
  • The direct cause of the symptoms is believed to be either constriction or dilation of blood vessels in the brain. (wikipedia.org)
Severe2
  • 1) cardiac symptoms including a weakened and enlarged heart, (2) neurological symptoms including recurrent seizures, and intellectual disability, and (3) severe multisystem involvement. (cdghub.com)
  • Quantitatively severe hypocalcemia can sometimes present with few symptoms, if onset has been protracted and chronic. (bmj.com)
Body's1
Type4
  • The treatment may involve one or a combination of multiple treatment modalities, which depend on the extent and type of cancer. (medicinenet.com)
  • Symptoms vary depending on type of mutation and the severity of the DOLK deficiency 1-7 . (cdghub.com)
  • In view of the findings on these two kindreds and the analysis of those in the literature, we conclude that type I PHA includes two clinically and genetically distinct entities with either renal or multiple target organ defects. (tau.ac.il)
  • Post-COVID-19 conditions might in- we analyzed variables for encounter type (inpatient, clude symptoms of nonspecific chest pain, fatigue, outpatient including emergency), encounter date se- and malaise, as well as cardiomyopathy, renal failure, quence variables (length of stay, admission and dis- lung disease, and venous thromboembolism. (cdc.gov)
Adrenal1
  • Arginine vasopressin deficiency and growth retardation are the most significant presenting symptoms in children with hypophysitis, different from teenagers in whom adrenal insufficiency, hypogonadism, headache, or diplopia might be the leading ma. (endocrine-abstracts.org)
Endocrinology1
  • SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of acute hypocalcaemia in adult patients. (bmj.com)
Conditions8
  • Glucocorticoid replacement therapy (GRT) was "systematically supplemented during acute stressful conditions with any recurrence of symptoms", the investigators note. (medwirenews.com)
  • GAPS Nutritional Protocol is the baseline treatment for all these conditions and symptoms. (gaps.me)
  • Some treatable medical conditions can cause Dementia symptoms, so it's important to determine the underlying cause. (mentalhealthhelpcenter.com)
  • symptoms or abnormalities that are common in PHACE but rarely seen in other medical conditions. (childrenshospital.org)
  • A Whole Health approach to women's health incorporates complementary and integrative practices, including supplements and herbal remedies, to improve health and well-being and manage symptoms related to underlying conditions. (va.gov)
  • Healthcare providers and patients are encouraged to set achievable goals through shared decision-making, and to approach treatment by focusing on specific symptoms (e.g., headache) or conditions (e.g., dysautonomia). (cdc.gov)
  • Post-COVID Conditions can also include development of new or recurrent symptoms or new conditions after the symptoms of acute COVID-19 illness have resolved. (cdc.gov)
  • However, some continue to have persistent, emergent, and re-emergent symptoms and conditions after this acute phase. (cdc.gov)
Organ3
  • Any organ, any system, any cell can show symptoms of distress. (gaps.me)
  • Other symptoms associated with Sturge-Weber can include eye and internal organ irregularities. (sturge-weber.org)
  • She had also increased salivary and sweat electrolytes consistent with PHA resulting from multiple organ unresponsiveness to mineralocorticoids. (tau.ac.il)
Hypertension1
  • Following a study and publication in 2007, it is also thought SSRIs, uncontrolled hypertension, endocrine abnormality, and neurosurgical trauma are indicated to potentially cause vasospasm. (wikipedia.org)
Patients10
  • For the vast majority of patients, all symptoms disappear on their own within three weeks. (wikipedia.org)
  • The key symptom of RCVS is recurrent thunderclap headaches, which over 95% of patients experience. (wikipedia.org)
  • Vasospasm is common post subarachnoid hemorrhage and cerebral aneurysm, but in RCVS only 25% of patients have symptoms post subarachnoid hemorrhage. (wikipedia.org)
  • In a study of 11 symptomatic patients by Rao and colleagues, 8 patients initially had visual symptoms. (medscape.com)
  • 3] In another study, by Eguchi and co-authors, visual symptoms occurred in 47% of patients. (medscape.com)
  • Some patients with mild symptoms have successfully received heart transplants, which have the potential to be curative. (cdghub.com)
  • Patients with mild symptoms of DOLK-CDG have received successful heart transplants that may be curative 10,11 . (cdghub.com)
  • The image below depicts distinctive pigmentation that can be seen in patients with fibrous dysplasia and endocrine abnormalities. (medscape.com)
  • Some patients have had additional symptoms such as dyspnea, throat closing, or nausea and vomiting that suggest anaphylaxis. (nih.gov)
  • In palliative care, patients receiving corticosteroids for symptoms such as fatigue, anorexia, refractory nausea and vomiting or adjuvant analgesia and symptomatic treatment of cord compression or raised intracranial pressure, Dexamethasone phosphate/DEMO may be administered subcutaneously (see section 4.2) as an alternative to the oral route when the latter is unacceptable or no longer feasible. (who.int)
Complications2
  • Other treatment focuses of managing specific symptoms and preventing complications. (cdghub.com)
  • Throughout the life of the individual, interrelated symptoms may manifest in glaucoma, cerebral blood flow abnormalities, headaches, and various other complications. (sturge-weber.org)
Vascular2
  • Rupture has never get senior colleagues in vascular abnormalities on the white curds. (sci-ed.org)
  • Vascular dementia, or multiple strokes. (netwellness.org)
Include2
  • Common symptoms of exposure include ear, nose and throat irritation, nausea and headaches. (naturalnews.com)
  • Physical symptoms include weakness, tremors and difficulty walking. (netwellness.org)
Acute COVID-191
  • Ongoing symptoms might follow acute COVID-19. (cdc.gov)