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  • stratified squamous e
  • It is characterized by the replacement of the normal stratified squamous epithelium lining of the esophagus by simple columnar epithelium with goblet cells (which are usually found lower in the gastrointestinal tract ). (wikipedia.org)
  • The mucosa, which is the inner most layer and lining of the esophagus, is composed of stratified squamous epithelium, lamina propria, and muscularis mucosae. (wikipedia.org)
  • distal
  • citation needed] In most cases of Boerhaave's syndrome, the tear occurs at the left postero-lateral aspect of the distal esophagus and extends for several centimeters. (wikipedia.org)
  • Causes
  • They can be similar, and there is a lot of overlap of symptoms when it comes to diagnosing causes of upper abdominal trouble. (healthtap.com)
  • Other causes of spontaneous perforation include caustic ingestion, pill esophagitis, Barrett's esophagus, infectious ulcers in patients with AIDS, and following dilation of esophageal strictures. (wikipedia.org)
  • As the intra-oesophageal pressure increases, the bolus within the oesophagus has nowhere to go superiorly (as the cricopharyngeus fails to relax) which causes the oesophagus to rupture. (wikipedia.org)
  • Consumer health resource center providing information on causes, symptoms and treatment. (dmoztools.net)
  • perforation
  • The main risks are infection, over-sedation, perforation, or a tear of the stomach or esophagus lining and bleeding. (wikipedia.org)
  • Spontaneous perforation of the esophagus most commonly results from a full-thickness tear in the esophageal wall due to a sudden increase in intraesophageal pressure combined with relatively negative intrathoracic pressure caused by straining or vomiting (effort rupture of the esophagus or Boerhaave's syndrome). (wikipedia.org)
  • Spontaneous effort rupture of the cervical esophagus, leading to localized cervical perforation, may be more common than previously recognized and has a generally benign course. (wikipedia.org)
  • In case of iatrogenic perforation common site is cervical esophagus just above the upper sphincter whereas spontaneous rupture as seen in Boerhaave's syndrome perforation commonly occurs in the lower (1/3)rd of esophagus. (wikipedia.org)
  • If esophageal perforation is suspected, even in the absence of physical findings,chest xray, water soluble contrast radiographic studies of the esophagus and a CT scan should be promptly obtained. (wikipedia.org)
  • In 1946, he wrote a paper for the first issue of Thorax on spontaneous rupture of the oesophagus (Boerhaave syndrome), in which he commented that "in the byways of surgery there can be few conditions more dramatic in their presentation and more terrible in their symptoms than spontaneous perforation of the oesophagus. (wikipedia.org)
  • Barrett NR. Spontaneous perforation of the oesophagus. (wikipedia.org)
  • Review of the literature and report of three new cases Thorax 1946.1:103-6 Barrett NR. Report of a case of spontaneous perforation of the oesophagus successfully treated by operation. (wikipedia.org)
  • cough
  • Other symptoms may include pain when swallowing, a hoarse voice, enlarged lymph nodes ("glands") around the collarbone, a dry cough, and possibly coughing up or vomiting blood. (wikipedia.org)
  • thoracic
  • In humans, the esophagus generally starts around the level of the sixth cervical vertebra behind the cricoid cartilage of the trachea, enters the diaphragm at about the level of the tenth thoracic vertebra, and ends at the cardia of the stomach, at the level of the eleventh thoracic vertebra. (wikipedia.org)
  • The lower esophagus lies behind the heart and curves in front of the thoracic aorta. (wikipedia.org)
  • The thoracic duct, which drains the majority of the body's lymph, passes behind the esophagus, curving from lying behind the esophagus on the right in the lower part of the esophagus, to lying behind the esophagus on the left in the upper esophagus. (wikipedia.org)
  • Barrett was a lecturer in surgery for the University of London (1935-1970), Surgeon to King Edward VII Sanatorium in Midhurst, Sussex (1938-1970), and Consulting Thoracic Surgeon to both the Royal Navy and the Ministry of Social Security (1944-1970). (wikipedia.org)
  • gullet
  • Normally, the oesophagus (or gullet) is lined by layers of short, squat cells, called squamous cells. (gastrolondon.co.uk)
  • The esophagus (American English) or oesophagus (British English) (/ɪˈsɒfəɡəs/), commonly known as the food pipe or gullet, is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach. (wikipedia.org)
  • difficulty
  • in the later stages of Barrett's esophagus there may be difficulty swallowing solids or liquids. (badgut.org)
  • Diseases may cause difficulty swallowing (dysphagia), painful swallowing (odynophagia), chest pain, or cause no symptoms at all. (wikipedia.org)
  • Symptoms often include difficulty in swallowing and weight loss. (wikipedia.org)
  • The first and the most common symptom is usually difficulty in swallowing, which is often experienced first with solid foods and later with softer foods and liquids. (wikipedia.org)
  • oesophageal
  • In addition to his work on oesophageal disease, Barrett also worked with Leonard Dudgeon, Professor of Pathology at the University of London, on the cytology of sputum in the diagnosis of pulmonary malignancy. (wikipedia.org)