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  • bone
  • In AML, underdeveloped leukemia cells accumulate in the patient's bone marrow, thereby causing the destruction and replacement of cells that would produce normal blood cells. (medigest.uk)
  • spinal
  • A small amount of cerebral spinal fluid (CSF) can be removed and sent for testing to look for leukemia cells or determine if there is an infection or other problems. (nyhq.org)
  • This procedure is done to look for leukemia cells in the spinal fluid. (ahealthyme.com)
  • CNS prophylaxis is treatment to make sure the leukemia does not spread to or stay in the fluid in and around the brain or spinal cord (called cerebrospinal fluid, or CSF). (cancer.ca)
  • There are no general signs or symptoms of ALL and no signs or symptoms that ALL has spread to the brain or spinal cord (called the central nervous system, or CNS) or anywhere else in the body. (cancer.ca)
  • Also called post-remission therapy, this phase of treatment is aimed at destroying any remaining leukemia in the body, such as in the brain or spinal cord. (mayoclinic.org)
  • chromosome
  • The genetic changes found in the leukemia cells of Ph-like ALL act like those linked with the Philadelphia chromosome. (cancer.net)
  • But, there are no signs of the Philadelphia chromosome in the leukemia cells. (cancer.net)
  • For example, in about 1 out of 4 people with ALL, their leukemia cells have the Philadelphia chromosome . (ahealthyme.com)
  • This chromosome contains the abnormal gene BCR-ABL that helps the leukemia cells grow. (ahealthyme.com)
  • Many leukemias involve genetic rearrangements, called translocations, in which some of the genetic material (genes) on a chromosome may be shuffled or swapped between a pair of chromosomes. (adam.com)
  • A certain abnormality called the Philadelphia chromosome is found in some people with acute lymphocytic leukemia. (mayoclinic.org)
  • blood
  • This exploration suggests an acute vestibular deficit in the right ear, and we decided to administer diazepam 5 mg i.v. in 30-45 minutes and to monitor the evolution while we wait for the results of an analysis that includes complete blood count, biochemistry, and basic coagulation tests. (hindawi.com)
  • The symptoms of acute lymphocytic leukemia may resemble other blood disorders or medical problems. (nyhq.org)
  • Acute lymphocytic leukemia (ALL) may initially present with musculoskeletal symptoms such as pain or swelling, even before appearance of blasts in the peripheral blood. (biomedcentral.com)