• Long construct MIPPSF in MSD did not have increased risk of construct failure and offered effective symptomatic relief, including for MM patients, without introducing a greater risk construct instability. (surgicalneurologyint.com)
  • Osseous destruction is often associated with mechanical instability, intractable pain, radiculopathy, and symptoms of cord compression. (ajnr.org)
  • Some factors such as individual treatment strategy, according to the histology of the primary tumor, plan of treatment strategies carried out in a multidisciplinary manner, risk-benefit of radiotherapy, assessment of the degree of spinal instability, improvement in communication and referral between specialists in oncology showed an increase in the survival of these patients. (bvsalud.org)
  • Four patients underwent surgical decompression and stabilization for spinal metastases causing instability, spinal cord compression, neurological deficit, or intractable pain. (edu.au)
  • Cervical spine laminoplasty is a treatment for multi-level cervical spondylotic myelopathy (CSM) without accompanying instability or cervical kyphosis. (jomi.com)
  • The surgeries did not resolve her problems of spinal instability and neurologic complications. (scienceopen.com)
  • The ALSYMPCA trial was a phase III, randomized, double-blind, placebo-controlled international study of radium-223 chloride (Xofigo®) plus best standard of care vs. placebo plus best standard of care in patients with CRPC, symptomatic bone metastases, and no known visceral metastatic disease. (urotoday.com)
  • However, to our knowledge, the use of this technique to treat spinal metastases, including MESCC, has not previously been reported. (hindawi.com)
  • Metastatic spinal disease (MSD) is the most common type (60%) of bone metastases in cancer patients. (surgicalneurologyint.com)
  • Surgical repair of spinal metastases from renal origin is often complicated by excessive bleeding. (ajnr.org)
  • Twenty spinal metastases from renal origin (17 patients) treated by preoperative embolization with polyvinyl alcohol particles were analyzed retrospectively. (ajnr.org)
  • A control group of 10 patients with 11 spinal metastases of renal origin underwent surgery without embolization. (ajnr.org)
  • Preoperative embolization of spinal metastases of renal origin with polyvinyl alcohol particles is safe and might reduce intraoperative blood loss significantly. (ajnr.org)
  • There is, however, limited data about the effect of preoperative embolization on intraoperative blood loss in spinal metastases of renal origin (6, 7, 15) . (ajnr.org)
  • This retrospective study included 18 consecutive patients with 21 symptomatic spinal metastases who underwent preoperative spinal angiography and embolization at our institution between October 1995 and August 1999. (ajnr.org)
  • The control group consisted of 10 consecutive patients with 11 spinal metastases of renal carcinoma, which were treated surgically without preoperative embolization between April 1994 and April 1997. (ajnr.org)
  • Although ENBs often recur and have an aggressive clinical course, spinal metastases are extremely rare and the underlying molecular mechanisms are poorly understood. (thejns.org)
  • Here, the authors describe a 50-year-old male with an aggressive ENB, initially treated with resection and chemotherapy/radiation, who developed multiple thoracic and lumbar spinal metastases. (thejns.org)
  • The authors performed targeted exome sequencing on both the resected primary tumor and biopsied spinal metastases, which revealed 12 total variants of unknown clinical significance in genes associated with the PI3K/AKT/mTOR pathway, chromatin remodeling, DNA repair, and cell proliferation. (thejns.org)
  • SUMMARY: We present a case series of eight consecutive patients with symptomatic spinal metastases due to thyroid carcinoma treated by our multidisciplinary team consisting of spinal surgeons, oncologists, and radiologists, with management of each case determined by our surgical algorithm. (edu.au)
  • The only patient with poorly differentiated thyroid cancer, which was refractory to radioiodine-131 died at 6 months after vertebroplasty procedures for symptomatic spinal metastases. (edu.au)
  • All remaining six patients who had well-differentiated papillary or follicular thyroid carcinoma were alive at an average of 50 months (range: 17-96 months) after diagnosis and treatment of symptomatic spinal metastases and were ambulant, independent, and able to perform activities of daily living and had no significant pain or neurologic symptoms. (edu.au)
  • CONCLUSION: The potential for long-term survival of several years following development of spinal metastases should be considered during the counseling and decision-making process for patients with thyroid cancer. (edu.au)
  • In pathologic conditions (eg, abnormalities of the odontoid bone or in the ligaments that keep these joints together), this displacement increases, and bone structures can pressure the spinal cord, producing clinical symptoms. (medscape.com)
  • Other allowed prior therapy for metastatic castration-sensitive prostate cancer (mCSPC): (a) maximum of 1 course of radiation and 1 surgical intervention for symptomatic control of prostate cancer (example, uncontrolled pain, impending spinal cord compression or obstructive symptoms). (uci.edu)
  • Maximum of 1 course of radiation and 1 surgical intervention for symptomatic control of prostate cancer (example, uncontrolled pain, impending spinal cord compression or obstructive symptoms). (who.int)
  • Even with anti-tuberculosis treatment, progressively worsening kyphosis may still occur over time, and the patient slowly develops symptoms of paralysis. (medicaltrend.org)
  • They presented with symptoms and signs due to cord compression at the lower thoracic and lumbar vertebrae. (who.int)
  • Right) MRI, T2 Sequence, Axial T2 sequence, demonstrating a central disk herniation causing compression and deformation of the spinal cord, causing symptoms of cervical myelopathy. (medscape.com)
  • These symptoms are based on a lack of or insufficient blood flow, which means that the spinal cord can no longer transmit signals from the brain. (medicinelearners.com)
  • The majority of the symptoms are caused by disc, bone, or ligaments pressing onto the nerve roots or cord. (themorrisonclinic.com)
  • Cervical disc bulging or herniation can cause pressure on the nerve roots and/or spinal cord causing symptoms including radiating arm, neck, and shoulder pain, loss of dexterity or motor function, and numbness and tingling in the hand or arm. (themorrisonclinic.com)
  • If your symptoms do not improve with other methods, Dr. Morrison may suggest spinal surgery . (themorrisonclinic.com)
  • Surgery is reserved for those who do not gain relief from non-operative forms of treatment, patients whose symptoms are increasing or worsening, and/or patients that present with a spinal condition which indicates the need for surgery. (themorrisonclinic.com)
  • An Anterior Cervical Discectomy and Fusion procedure, commonly known as ACDF surgery , is a type of cervical spine surgery from the front (anterior) of the neck (cervical) that often successfully addresses spinal symptoms. (themorrisonclinic.com)
  • Symptoms can become worse with flexion of the head, which even further drapes the spinal cord over the upper portion of C2. (uclahealth.org)
  • Surgical treatment is reserved for patients with symptoms refractory to non-operative management, neurological deficit, or severe spinal cord compression. (uclahealth.org)
  • Therefore, diabetic patients are at much higher risk for experiencing symptoms of Meralgia paresthetica than the general population and may benefit from an early evaluation by a peripheral nerve surgeon, and early surgical treatment before the nerve is irreversibly damaged. (drducicplasticsurgery.com)
  • Your cervical spine also forms a protective tunnel for the upper part of your spinal cord to pass through.Symptoms of c5-c6 disc herniation can include numbness, tingling, burning, weakness, problems with vision, and more. (best-mag.com)
  • Spinal cord compression symptoms include: Awkward or stumbling gait. (best-mag.com)
  • If symptoms continue, surgery may be recommended.In most cases cervical disc herniations improve with time and symptomatic treatment. (best-mag.com)
  • For the treatment of cerebral oedema , [CV004 trade name] may be given intravenously in an initial dose of 8 mg, followed by 4 mg every 6 hours intramuscularly, until the cerebral oedema symptoms have remitted. (who.int)
  • Anterior surgical decompression and stabilization are the treatments of choice for radiation-resistant metastatic spinal tumors, resulting in improved neurologic function and pain reduction in more than 80% of patients (4, 5) . (ajnr.org)
  • The extreme rarity of this type of presentation can pose a diagnostic dilemma, and in cases isolated to the spine, surgical treatment with posterior stabilization, decompression, and bone grafting gives a good functional outcome. (ijssurgery.com)
  • Surgery usually involves the removal of bone that is causing the compression and stabilization with a fusion. (uclahealth.org)
  • A 20-year-old female with HCS and progressive symptomatic BI, initially managed with posterior fossa decompression and occipital to cervical fusion, subsequently required cranial vault expansion due to symptomatic shifting of her cranium secondary to POCS. (thejns.org)
  • Surgery for treatment of spinal tuberculosis is divided into anterior, posterior and combined anterior and posterior approaches, such as: anterior debridement and bone grafting, anterior debridement and bone graft internal fixation, anterior debridement and bone graft combined with posterior internal fixation, and simple posterior Road lesion removal, bone grafting and internal fixation. (medicaltrend.org)
  • However, the front decompression of the thoracic spine via the posterior approach makes the operation extremely difficult and the risk of spinal cord injury during the operation is extremely high. (medicaltrend.org)
  • Under local anesthesia and light sedation, it determines the anterior and posterior spinal feeder arteries by selective catheterization of the cervical, intercostal, lumbar and sacral arteries, knowing that an initial global study by aortic opacification (or bilateral retrograde humeral for the cervical region) can simplify exploration. (medical-actu.com)
  • The anterior spinal vein is the main vein, but a posterior spinal vein can become opacified by the anastomotic network. (medical-actu.com)
  • Most often at high flow rates, they are multi-pediculated, almost always fed by ASA and one or more posterior spinal arteries. (medical-actu.com)
  • They rarely show enlargement of the spinal canal suggestive of an intraductal expansive process, erosion of the posterior border of the vertebral bodies or of a pedicle. (medical-actu.com)
  • Excluding pathology, the anterior spinal vein and the veins of the ponytail are never visible, the posterior spinal vein is visible in the lower and lumbar dorsal regions, but never above T4 and over 8 storeys. (medical-actu.com)
  • Facet hypertrophy caused additional posterior compression at C6-7. (scitechnol.com)
  • Arteriosclerosis or an embolism can restrict the blood supply to the anterior (belly) located anterior spinal artery and the posterior (back) located spinal artery. (medicinelearners.com)
  • Radiotherapy for acute metastatic epidural spinal cord compression (MESCC) involves conventional techniques and dose fractionation schemes, as it needs to be initiated quickly. (hindawi.com)
  • Metastatic epidural spinal cord compression (MESCC) is a common neurological complication of cancer and can have devastating consequences for patients [ 1 - 3 ]. (hindawi.com)
  • Nerve injury by a single episode of physical trauma is in one sense an acute compression neuropathy but is not usually included under this heading, as chronic compression takes a unique pathophysiological course. (wikipedia.org)
  • Despite the growing sophistication of radiotherapy techniques such as intensity-modulated radiotherapy (IMRT) and stereotactic body radiotherapy (SBRT) [ 2 , 3 ], conventional methods that use opposed 2 ports are still commonly used to treat acute symptomatic MESCC, probably because treatment must be initiated immediately [ 1 , 3 ]. (hindawi.com)
  • Spinal manifestations of NF1 include bone changes such as acute kyphoscoliosis at the cervical-thoracic junction and vertebral body anomalies, soft-tissue abnormalities such as dural ectasia and lateral meningocele, and various spinal tumors. (ajnr.org)
  • These include acute transverse myelitis, spinal cord compression, and various demyelinating disorders. (medicinelearners.com)
  • CV004 trade name] is indicated particularly for initial acute management where oral treatment is not feasible. (who.int)
  • SSE was defined as first use of EBRT to relieve skeletal pain, new symptomatic pathologic bone fracture, occurrence of spinal cord compression, or tumor-related orthopedic surgical intervention. (urotoday.com)
  • Prolonged periods of cycling can be associated with pudendal nerve entrapment, as there is often direct compression on the pudendal nerve between the nose of the bicycle seat and pubic bone. (wikipedia.org)
  • Background: Macrophages play an important role in regulating the course of spinal tuberculosis within the bone microenvironment. (bvsalud.org)
  • Methods: We established study cohorts for spinal tuberculosis, collected bone marrow blood samples, isolated macrophage exosomes, and performed exosome miRNA sequencing. (bvsalud.org)
  • In the early stage, patients without severe bone destruction, giant abscesses and nerve tissue compression can be cured with anti-tuberculosis drugs. (medicaltrend.org)
  • 6. Does spinal tuberculosis need bone grafting and internal fixation? (medicaltrend.org)
  • Some patients with spinal tuberculosis cause bone destruction of the vertebral body, loss of spinal stability, or large bone defects after surgical removal of the lesion. (medicaltrend.org)
  • At this time, bone grafting and internal fixation are required to restore spinal stability. (medicaltrend.org)
  • Bone graft fusion and internal fixation is an important method for spinal tuberculosis surgery. (medicaltrend.org)
  • 1, 2] This procedure involved removing the symptomatic disc from an anterior approach without placement of a bone graft. (medscape.com)
  • 7] ACDF similarly involves removing the symptomatic cervical disc with an added step of placing bone graft to encourage bony fusion of the upper and lower vertebral body. (medscape.com)
  • When referring to the bone graft techniques, namely ACDF and ACDFI, surgical choices of using autograft and allograft exist. (medscape.com)
  • Treatment of long bone pseudoartrosis with bone loss by segment transfer method with external fixation. (medicanainternational.com)
  • These osteochondromas usually continue to grow until shortly after puberty and may lead to bone deformities, skeletal abnormalities, short stature, nerve compression and reduced range of motion. (orthopedicshealth.com)
  • Conservative treatments should always be contemplated as an alternative method for patients with poor bone stock. (scienceopen.com)
  • Timely diagnosis is important as untreated chronic nerve compression may cause permanent damage. (wikipedia.org)
  • Metastatic prostate cancer was most often symptomatic at the time of diagnosis. (springeropen.com)
  • This paper describes the clinical manifestations, diagnosis and management of schistosomiasis of the spinal cord in 5 patients attending Shaab and Ibn Khuldoun Hospitals, Khartoum from 1997 to 2007. (who.int)
  • Early diagnosis is important because the clinical course depends on an effective treatment, performed early after the appearance of the symptomatology. (medical-actu.com)
  • however, diagnosis and access to timely treatment are often delayed, which contribute to significant disability and dependence. (jmir.org)
  • Supporting early diagnosis and access to timely treatment is a critical priority. (jmir.org)
  • The appropriate therapy for neurogenic bladder and a successful treatment outcome are predicated upon an accurate diagnosis through a careful medical and voiding history, together with a variety of clinical examinations, including urodynamics and selective radiographic imaging studies. (medscape.com)
  • This Statement is one of a series of four Statements on diagnosis, treatment, and control of tuberculosis. (cdc.gov)
  • Embolization has been used as a presurgical maneuver in the treatment of a variety of primary and secondary spinal tumors (6-22) . (ajnr.org)
  • This phase II trial studies how well olaparib works in treating patients with bladder cancer and other genitourinary tumors with deoxyribonucleic acid (DNA)-repair defects that has spread to other places in the body (advanced or metastatic) and usually cannot be cured or controlled with treatment. (bcan.org)
  • A spinal cord infarction occurs much more frequently as a result of blockages in the arteries caused by tumors, aortic aneurysms or aortic dissections. (medicinelearners.com)
  • 3 , 5 ] Here, we present our experience with 20 consecutive patients who underwent MIPPSF for the treatment of MSD, including those with multiple myeloma (MM). (surgicalneurologyint.com)
  • For treatment recommendations for patients with a life expectancy ≥20 y, see initial therapy for Low Risk of Recurrence, below. (medscape.com)
  • It is the standard first-line treatment for patients with advanced NSCLC with ALK gene rearrangement. (mycancergenome.org)
  • Despite the effectiveness of these new treatments, all patients will virtually experience a relapse. (mycancergenome.org)
  • Patients who have leptomeningeal disease (LM) or carcinomatous meningitis ( CM ) will be eligible if the LM/ CM is visualized on MRI or if documented baseline cerebral spinal fluid (CSF) positive cytology is available and asymptomatic and neurologically stable (including patients controlled with stable or decreasing steroid use within the last week prior to study entry). (mycancergenome.org)
  • The study was carried out to exhaust the scientific literature regarding surgery associated with radiotherapy in patients suffering from metastatic spinal cord compression and to assist in the decision of oncology physicians and professionals in choosing the best treatment for the patient. (bvsalud.org)
  • The researchers carried out a descriptive study using bibliometric and scientometric methods and found that the combination of surgery with postoperative radiotherapy is effective and more efficient than these alone for the treatment of patients affected by metastatic neurological compression. (bvsalud.org)
  • A literature review performed revealed three other cases of surgical intervention for BI in patients with HCS and clinicopathological characteristics of each case was compared to the present illustrative case. (thejns.org)
  • POCSs in patients with BI complicate traditional surgical approaches, necessitating more invasive techniques to secure all mobile cranial parts for optimal outcomes. (thejns.org)
  • After completion of study treatment, patients are followed up at 4 weeks, every 2 months for 1 year, then every 3 months thereafter. (bcan.org)
  • one of these patients required subsequent surgical decompression for spinal cord compression. (edu.au)
  • All patients underwent total thyroidectomy for the primary cancer and adjuvant radioiodine-131 treatment. (edu.au)
  • The aim of this study was to characterize the radiologic presentation of patients with neurofibromatosis type 1 with widespread spinal disease and to correlate it to clinical presentation and outcome. (ajnr.org)
  • We conducted a historical cohort study of adult patients with neurofibromatosis type 1 with spinal involvement. (ajnr.org)
  • The WHO has emphasised the integrated approach to palliative care in the treatment of cancer patients. (jpalliativecare.com)
  • The present study is an audit at a centre in North India (PGIMER, Chandigarh) where palliative care is integrated with the oncology services with the aim to see the number of patients who received antineoplastic treatment in the last 30 days of their lives. (jpalliativecare.com)
  • Patients responded well to surgical decompression and treatment with praziquantel and oral steroids. (who.int)
  • Le présent article décrit les manifestations cliniques, le diagnostic et la prise en charge de la schistosomiase médullaire chez cinq patients admis dans les hôpitaux Shaab et Ibn Khaldoun de Khartoum entre 1997 et 2007. (who.int)
  • Les motifs de consultation des patients étaient des symptômes et des signes causés par la compression de la moelle épinière au niveau des vertèbres lombaires et thoraciques inférieures. (who.int)
  • For high-risk patients, does prophylaxis against venous thromboembolism (VTE) with the combined modalities of leg intermittent pneumatic compression (IPC) and pharmacologic prophylaxis provide more protection than either treatment alone? (aafp.org)
  • To assess the effectiveness of intermittent pneumatic compression (IPC) combined with pharmacologic prophylaxis versus single modalities in preventing DVT in high-risk patients. (aafp.org)
  • All patients in the trials selected were surgical or trauma patients. (aafp.org)
  • It gained popularity in the 1950s when Spine Surgeons performed this Surgery, to Treat Patients suffering the agony of Back Pain and Deformity, but Surgical Technology was not much advanced then. (drpuravpatel.com)
  • Hormonal treatment of advanced prostate cancer should be consideredfor patients who have stages C and D1 disease, a high risk of recurrenceafter local therapy, or prostate-specific antigen-measured recurrenceafter local treatment. (cancernetwork.com)
  • Since 1947, Dana-Farber's sole focus has been to provide expert cancer care and groundbreaking treatments for adult and pediatric patients. (dana-farber.org)
  • For the expansion cohort: Patients must have had disease progression on alectinib (including patients who received alectinib as first-line treatment). (dana-farber.org)
  • Patients must have recovered from treatment toxicities to ≤ Grade 1 or to their pretreatment levels except for adverse events (AEs) that in the investigator's judgment do not constitute a safety risk for the patient. (dana-farber.org)
  • Patients who have received prior treatment with checkpoint inhibitors are eligible. (dana-farber.org)
  • 2017. The Health Impact of Adult Cervical Deformity in Patients Presenting for Surgical Treatment: Comparison to United States Population Norms and Chronic Disease States Based on the EuroQuol-5 Dimensions Questionnaire. . (cornell.edu)
  • Comme nous l'avons vu dans les chapitres précédents, les directives de pratique clinique utilisent différents systèmes de classification pour guider la prise en charge de ces patients. (fullphysio.com)
  • Il est bon de noter que quelle que soit l'approche utilisée, les guidelines des récentes études soutiennent l'utilisation de la réassurance, des conseils et de l'éducation thérapeutique pour la plupart des patients considérés comme présentant un faible risque de chronicité en phase aigüe (Blanpied et al. (fullphysio.com)
  • In some patients, the spinal cord can be compressed by bony osteophytes (spurs), herniated discs or by other soft tissues such as ligaments. (themorrisonclinic.com)
  • Patients with thalassemia minor usually do not require any specific treatment. (medscape.com)
  • Patients generally become symptomatic when the displaced vertebral segment causes sufficient pressure on the upper spinal cord or lower portion of the brainstem. (uclahealth.org)
  • Reply to the letter to the editor regarding "a clinical prediction model to assess surgical outcome in patients with cervical spondylotic myelopathy: Internal and external validation using the prospective multicenter AOSpine North American and International datasets of 743 patients. (illinois.edu)
  • Although respiratory failure (RF) can be associated with skull base abnormalities due to brainstem compression, most cases occur in pediatric patients and quickly resolve. (bepress.com)
  • the main pathology is caused history of travel to schistosomiasis- of 3 patients showed swelling of the by a granulomatous inflammation endemic areas, imaging and laboratory spinal cord at D12 to L1 or L2 with around eggs trapped in the tissues [2,3]. (who.int)
  • A 6-mo regimen consisting of isoniazid, rifampin, and pyrazinamide given for 2 mo followed by isoniazid and rifampin for 4 mo is the preferred treatment for patients with fully susceptible organisms who adhere to treatment. (cdc.gov)
  • CV004 trade name] may also be used in the treatment of coronavirus disease 2019 (COVID-19) in adult and adolescent patients (aged 12 years and older with body weight of at least 40 kg) who require supplemental oxygen therapy. (who.int)
  • If not treated in time, the entire vertebral body and its appendages will be destroyed, leading to spinal deformities, even compressing the spinal cord and causing paralysis. (medicaltrend.org)
  • Imaging examination showed: T5 vertebral body compression fracture, accompanied by vertebral body soft tissue space. (medicaltrend.org)
  • First and foremost, let me tell you that this procedure of Relieving Pressure from the Spinal Nerves (one of the major Cause of Back/Neck & related Pain) and Giving Support to your diseased Vertebral Column (Spine) is centuries old! (drpuravpatel.com)
  • Prophylactic vertebroplasty for adjacent vertebra has been reported to reduce the complications of junctional compression fractures but has raised a new problem of vertebral subluxation. (scienceopen.com)
  • Adjacent segmental disease, junctional fracture, and vertebral subluxation are familiar complications following instrumented spinal fusion surgeries for osteoporotic spines. (scienceopen.com)
  • Chemotherapy and hormone therapy are ineffective, making radiation and surgery the mainstays of treatment. (ajnr.org)
  • When does spinal tuberculosis need surgery? (medicaltrend.org)
  • The purpose of spinal tuberculosis surgery is to remove tuberculosis foci, relieve nerve compression, rebuild spinal stability, save nerve function and rebuild spinal stability as much as possible. (medicaltrend.org)
  • Surgery requires direct removal of ventral compression of the spinal cord. (medicaltrend.org)
  • This endoscopic type of spinal surgery encompasses many procedural variations, but all seek to remove a portion of a bulging disc thought to be compressing a spinal nerve root or impinging on the spinal cord. (herniated-disc-pain.org)
  • Well, this is the right time to get down to 'Learning a Few Facts about this dreaded Spinal Surgery' and what it is all about. (drpuravpatel.com)
  • Reoperation Rates After Surgery for Degenerative Cervical Spine Disease According to Different Surgical Procedures: National Population-based Cohort Study. (cornell.edu)
  • The success of the surgery depends on how long the nerve has been compressed, the severity of the compression, the extent of nerve damage due to injury and the possible presence of underlying medical or spine problems. (drducicplasticsurgery.com)
  • If you are not sure about your eligibility for surgery, and if you are not in the Washington, D.C. area, you can send me your records so I can determine if you are a good candidate for treatment. (drducicplasticsurgery.com)
  • The patient had no clinical signs of cord compression. (medscape.com)
  • Abiraterone acetate plus prednisone (AA-P) is an established standard of care for the treatment of participants with mCSPC and is included in widely accepted clinical treatment guidelines. (uci.edu)
  • Selecting initial treatment requires assessing the risk of the disease spreading or progressing, which is based on evaluating the patient's life expectancy, comorbidities, biopsy grade (Gleason score), clinical stage, and prostate-specific antigen (PSA) level. (medscape.com)
  • Progressive alterations in pressure dynamics between the intracranial and spinal compartments are believed to be responsible for the development of clinical signs of CM/SM. (vin.com)
  • This international, peer-reviewed Open Access journal by Dove Medical Press focuses on reporting of clinical studies, outcomes and safety in all therapeutic areas and surgical intervention areas. (scienceopen.com)
  • The initial dose should be maintained or adjusted until the clinical response is satisfactory and, if no suitable clinical response is obtained after a reasonable period of time, [CV004 trade name] should be stopped and the patient's treatment changed. (who.int)
  • 2. What kind of deformity will appear with spinal tuberculosis? (medicaltrend.org)
  • 2018. Outcomes of Operative Treatment for Adult Cervical Deformity: A Prospective Multicenter Assessment With 1-Year Follow-up. . (cornell.edu)
  • Surgical intervention in HCS is challenging due to severe osteoporosis, ligamentous laxity, POCSs, and extreme skeletal deformities. (thejns.org)
  • Gait disturbances are a strong indication for surgical intervention. (jomi.com)
  • Initially reported to occur rarely, it is now considered a potential late complication of spinal fusion that can necessitate further surgical intervention and adversely affect outcomes. (scienceopen.com)
  • A key secondary endpoint was time to first symptomatic skeletal event (SSE). (urotoday.com)
  • Nerve compression can be secondary to other medical conditions. (wikipedia.org)
  • Treatment protocols for prostate cancer are provided below, including general treatment recommendations and those for localized prostate cancer, for recurrent disease, and for advanced or metastatic disease. (medscape.com)
  • 2016. Failure of Intraoperative Monitoring to Detect Postoperative Neurologic Deficits: A 25-year Experience in 12,375 Spinal Surgeries. . (cornell.edu)
  • Although multimodal intraoperative spinal cord monitoring provides greater accuracy, transcranial electrical stimulation motor evoked potential (TcMEP) monitoring became the gold standard for intraoperative spinal cord monitoring. (thejns.org)
  • ABSTRACT Schistosomiasis of the spinal cord is an uncommon but potentially curable form of schistosomiasis, if diagnosed and managed early. (who.int)
  • A spinal cord infarction is an emergency and is a complication of various vascular diseases such as aortic aneurysms, arteriosclerosis or others. (medicinelearners.com)
  • As a result, males may be more likely to have extramedullary hematopoiesis and thus more likely to require splenectomy or to develop spinal cord compression, an uncommon but serious complication of paraspinal extramedullary hematopoiesis. (medscape.com)
  • There are countless varieties of this operation, but all demonstrate minimally invasive surgical techniques using the latest high tech equipment to reduce trauma to the patient. (herniated-disc-pain.org)
  • Minimally invasive partial disc removal procedures are most often used to treat herniated discs diagnosed as causing particular nerve compression syndromes. (herniated-disc-pain.org)
  • Even with successful operations, there is a great risk of spinal disc re-herniation or pain moving to a new location. (herniated-disc-pain.org)
  • In CM/SM, as in Chiari type I of people, the caudal aspect of the cerebellum is often projecting into or through (herniation) the foramen magnum, contributing to obstruction of CSF flow between intracranial and spinal compartments. (vin.com)
  • The authors' aim is to demonstrate the use of IA ICG angiography to aid in the surgical treatment of a perimedullary thoracic arteriovenous fistula (AVF) in a hybrid operating room (OR). (thejns.org)
  • In view of the patient's condition, because the lesion is located in the upper thoracic spine, the front of the spinal cord is compressed significantly, and only indirect decompression through the rear, the surgical effect is extremely limited. (medicaltrend.org)
  • Subsequently, we constructed a target gene network for these miRNAs and performed KEGG pathway enrichment analysis to explore the potential signaling mechanisms involved in regulating the disease course of spinal tuberculosis. (bvsalud.org)
  • Exosome miRNA-seq demonstrated that 28 miRNAs were up-regulated, while 34 miRNAs were down-regulated in individuals with spinal tuberculosis. (bvsalud.org)
  • GO analysis and KEGG pathway enrichment analysis indicated that the differentially expressed miRNAs were involved in various biological processes, cell components, molecular functions, and signaling pathways, which collectively contribute to the regulation of the disease course of spinal tuberculosis. (bvsalud.org)
  • qRT-PCR validation further confirmed the significant up-regulation of miRNA-125b-5p in spinal tuberculosis. (bvsalud.org)
  • The ROC curve revealed that miR-125b-5p is a potential diagnostic biomarker for spinal tuberculosis. (bvsalud.org)
  • Moreover, construction of the miRNA-125b-5p target gene network and subsequent KEGG enrichment analysis highlighted the importance of MAPK, TNF, Ras, Rap1, and the PI3K-Akt signaling pathways in the regulation of the disease course of spinal tuberculosis. (bvsalud.org)
  • 1. What are the hazards of spinal tuberculosis? (medicaltrend.org)
  • Some spinal tuberculosis abscesses will penetrate the skin to form a fistula, puncture organs or blood vessels, and form corresponding complications, which will cause great damage to the patient and a high rate of disability and teratogenesis. (medicaltrend.org)
  • Spinal tuberculosis tends to occur in the anterior column. (medicaltrend.org)
  • 3. Will spinal tuberculosis cause paraplegia? (medicaltrend.org)
  • 4. Under what circumstances do spinal tuberculosis require surgical treatment? (medicaltrend.org)
  • 5. What are the surgical methods for spinal tuberculosis? (medicaltrend.org)
  • Multiple-drug-resistant tuberculosis (i.e., resistance to at least isoniazid and rifampin) presents difficult treatment problems. (cdc.gov)
  • This patient was treated with image-guided 3DCRT (IG-3DCRT) alone using a FIF technique and a unique hypofractionated dose fractionation scheme, which resulted in good tumor control and sufficient cord decompression, which in turn allowed a delayed but gradual improvement in her severe neurological dysfunction. (hindawi.com)
  • Therefore, I do not find injections, chronic pain medications, radiofrequency ablation (RFA), or spinal cord stimulators appropriate since they all are symptomatic treatments only. (drducicplasticsurgery.com)
  • Catheter-based radiofrequency ablation has long been recognized as an effective treatment for refractory ventricular tachycardia (VT). (bepress.com)
  • It is known colloquially as a trapped nerve, though this may also refer to nerve root compression (by a herniated disc, for example). (wikipedia.org)
  • 16] Proponents and detractors for these different procedures can be found throughout the scientific and surgical community. (medscape.com)
  • The purpose of this article is not to compare and contrast these different surgical techniques or plate technologies but to highlight the role of these 3 procedures for treatment of cervical spine disease. (medscape.com)
  • The research study procedures include screening for eligibility, study treatment including evaluations, surveys, optional biopsies, and follow up visits. (clincosm.com)
  • Participants with radiation or surgical interventions to all known sites of metastatic disease will be excluded from trial participation. (uci.edu)
  • Metastatic disease (Stage IV American Joint Committee on Cancer, Version 7) not amenable to local treatment. (genentech-clinicaltrials.com)
  • Surgical decompression was performed within 2 days after embolization. (ajnr.org)
  • The arteriography introduced by Djindjian (1962), alone allows to specify the angioarchitecture, opening the door to endovascular treatment by spinal embolization. (medical-actu.com)
  • Three groups of vascular malformations dominate: medullary arteriovenous malformations (AVM), peri-arterial arteriovenous fistulas (AVF) and spinal meningeal FAF. (medical-actu.com)
  • Also, it expanded the horizons for Treating various Spinal Diseases & Disorders, which was not much possible earlier. (drpuravpatel.com)
  • Damage to an extravertebral, i.e. supplying, artery or the aorta leads to a spinal cord infarction more frequently than due to intrinsic disorders of the spinal arteries. (medicinelearners.com)
  • Journal of Spinal Disorders and Techniques. (illinois.edu)
  • 10) Kiliç B, Uysal M, Cinar BM, Ozkoç G, Demirörs H, Akpinar S. Early results of treatment of proximal humerus fractures with the PHILOS locking plate. (medicanainternational.com)
  • Spinal vascular involvement associated with vasculitis should also be considered as a cause. (medicinelearners.com)
  • None had hepato- japonicum live in the mesenteric vascular somiasis of the spinal cord. (who.int)
  • The term "Saturday night palsy" is used for a radial nerve injury caused by prolonged compression of the nerve at the spiral groove. (wikipedia.org)
  • However, its effects and mechanisms in spinal cord ischemia-reperfusion injury have not been fully established. (bvsalud.org)
  • In this study, the mechanisms of polydatin against spinal cord ischemia-reperfusion injury were investigated via network pharmacology, molecular docking and molecular dynamics simulation. (bvsalud.org)
  • METHODS: Spinal cord ischemia-reperfusion injury-related targets were obtained from the GeneCards database, while polydatin-related action targets were obtained from the CTD and SwissTarget databases. (bvsalud.org)
  • Molecular docking showed that polydatin had the highest binding affinity for MAPK3, suggesting that MAPK3 is a key target of polydatin against spinal cord ischemia-reperfusion injury. (bvsalud.org)
  • CONCLUSIONS: Polydatin exerts its effects on spinal cord ischemia-reperfusion injury through multiple targets and pathways. (bvsalud.org)
  • MAPK3 may be a key target of polydatin in spinal cord ischemia-reperfusion injury. (bvsalud.org)
  • Eventually, the patient remained with a Frankel Grade C spinal cord injury. (scienceopen.com)
  • Spinal pain was the most noted reason for consultation. (springeropen.com)
  • Spinal pain (46.9%) and changes in general condition (36.6%) were the most common reasons for consultation (Table 1 ). (springeropen.com)
  • Surgical treatment with anterior resection of osteophytes and anterior cervical discectomy with fusion relieved the patient's dysphagia and neck pain. (scitechnol.com)
  • Anyone who is about to suffer a spinal cord infarction (spinalis anterior syndrome) feels a sudden pain in the back with a ring-shaped radiating tightness. (medicinelearners.com)
  • Most cases of cervical herniated disc pain can be successfully managed with nonsurgical treatments, such as over-the-counter pain medications, physical therapy to strengthen and stretch the neck, ice or heat packs, and/or activity modifications to avoid painful movements until the pain has subsided.Treatment with rest, pain medication, spinal injections, and physical therapy is the first step to recovery. (best-mag.com)
  • The signal transmitted by the brain is routed through 2 intermediate segments (the brainstem and the sacral spinal cord) prior to reaching the bladder. (medscape.com)
  • A surgical nerve decompression can relieve pressure on the nerve but cannot always reverse the physiological changes that occurred before treatment. (wikipedia.org)
  • The incidence of survival from metastatic spinal disease (MSD) continues to rise. (surgicalneurologyint.com)
  • Review the definition, etiology, incidence, and risk factors associated with as well as potential treatment options. (scienceopen.com)
  • Incidence of symptomatic adjacent segment disease is lower, however, ranging from 5.2 to 18.5% during 44.8 to 164 months of follow-up observation. (scienceopen.com)
  • Radiotherapy, either alone or following surgical decompression, still has a pivotal role in the management of MESCC [ 1 - 3 ]. (hindawi.com)
  • Currently, the optimal treatment includes maximal resection combined with radiotherapy and/or chemotherapy. (thejns.org)
  • Dr. Morrison may determine that an ACDF procedure is a good option for you if you require an interbody fusion, are skeletally mature, and have gone through six weeks of non-surgical treatment. (themorrisonclinic.com)
  • This case report is a rare and an extreme example with many surgical complications caused by repeated instrumented fusion for osteoporotic spine in a single patient. (scienceopen.com)
  • The development of pathology at the mobile segment next to a lumbar or lumbosacral spinal fusion has been termed adjacent segment disease. (scienceopen.com)
  • Foot, spinal and hip pathologies are likely underestimated. (bmj.com)
  • Bowing of the forearm and ankle are the problems that most often require surgical correction. (orthopedicshealth.com)
  • The malformation is best visualized on a midsagittal view (preferably T2-weighted), which includes the caudal fossa and cranial cervical cord. (vin.com)