AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth Care
Spinal Cord CompressionSpinal NeoplasmsSpinal CordSpinal Cord NeoplasmsSpinal Cord InjuriesLaminectomyThoracic VertebraeEpidural NeoplasmsCervical VertebraeDecompression, SurgicalSpinal Cord DiseasesParaplegiaHematopoiesis, ExtramedullarySpinal DiseasesMyelographyScheuermann DiseaseEpidural SpaceSpinal CanalHematoma, Epidural, SpinalMagnetic Resonance ImagingHyperostosisParaparesisRheumatic NoduleOsteochondromaBalloon EmbolectomyOdontoid ProcessBone NeoplasmsEpidural AbscessExostoses, Multiple HereditaryQuadriplegiaDiphosphonatesArachnoid CystsArachnoidTuberculosis, SpinalHemangiomaData CompressionSpinal FusionFractures, SpontaneousSpineNerve Compression SyndromesSpinal FracturesNeurosurgical ProceduresTreatment OutcomeSpinal Cord IschemiaUmbilical CordSpinal OsteophytosisLumbar VertebraeTomography, X-Ray ComputedRecovery of FunctionStockings, CompressionInjections, SpinalCancer Care FacilitiesFatal OutcomeRetrospective StudiesSpinal Nerve RootsFractures, CompressionIntervertebral DiscTime FactorsSpinal StenosisOsteochondromatosisCervical AtlasLigamentum FlavumSpinal NervesPalliative CareMotor Neurons
DeficitsStenosisSymptomsTumorsVertebralSpineAcuteInstabilityDeficitMyelopathyCanalSevereDisordersVascularStabilizationComplicationRadiculopathyResults in lasting neurLumbar spinalFractureDevelop spinal cord compreInjuriesPosteriorClinicalDiagnosisSyringomyeliaAbnormalitiesIncidenceTumorSurgeryMetastatic spinalNerve rootNervesCentral spinal cordMetastasesSyrinxForamen magnumHydrocephalusIschemiaDural sacAnteriorPrognosisOnsetWeaknessBoneSurgical decompressionOccurOccursInfarctionAbstract
Deficits14
  • In both groups, the nature of neurological deficits influenced the thinking, with the most time-sensitive issues such as myelopathy and weakness driving the decision-making towards performing spinal surgery first," Liu and colleagues wrote. (medpagetoday.com)
  • Both groups agreed that neurological deficits in the patients would influence their decision. (medpagetoday.com)
  • A physical examination revealed kyphoscoliotic deformity, a café au lait spot, tenderness at the thoracolumbar region, and neurological deficits. (ijssurgery.com)
  • Diabetics are also often affected by neurological deficits caused by an infarction in the spinal cord. (medicinelearners.com)
  • Neurological deficits can then already recede in the next few days. (medicinelearners.com)
  • Radiculopathy, which involves neurological deficits stemming from spinal nerve root compression, such as tingling, numbness, or weakness that goes into an arm or leg. (spine-health.com)
  • Myelopathy, which involves neurological deficits stemming from spinal cord compression, such as tingling, numbness, or weakness that goes into both arms and/or legs. (spine-health.com)
  • Cauda equina syndrome, which results in neurological deficits from compression of the cauda equina (spinal nerve roots that continue below the spinal cord). (spine-health.com)
  • While rare, it is also possible for spinal stenosis to present primarily as neurological deficits, such as numbness and/or weakness, rather than pain. (spine-health.com)
  • If the spinal cord becomes compressed, pain and/or neurological deficits may be experienced anywhere in the body beneath the level of compression, including the legs. (spine-health.com)
  • If the spinal cord becomes compressed in the thoracic spine, pain and/or neurological deficits may be experienced at the level of compression (mid back) or below. (spine-health.com)
  • Whereas arterial occlusion in the spinal region quickly becomes symptomatic by neurological deficits, venous outflow obstruction may be clinically unnoticed for much longer and usually manifests as a slowly progressive neurological deficit. (fortunejournals.com)
  • Peri-acute intraspinal grafting of HSSC can represent an effective therapy which ameliorates motor and sensory deficits after traumatic spinal cord injury. (biomedcentral.com)
  • Syringomyelia is a condition characterised by fluid filed cavities (syrinxes or syringes) within the central spinal cord and the resulting damage produces clinical signs of pain and neurological deficits. (marysfamilymedicine.org)
Stenosis20
  • It is associated with potentially serious complications such as foramen magnum and spinal stenosis, which result in increased morbidity and mortality. (medscape.com)
  • In people with achondroplastic dwarfism, stenosis of the spinal canal is secondary to abnormalities of endochondral ossification with premature synostosis of the ossification centers of the vertebral body and the posterior arch. (medscape.com)
  • Central spinal stenosis and lateral recess stenosis can pinch one or more nerves in the lower back, since the spinal cord has already separated into the cauda equina structure. (herniated-disc-pain.org)
  • In cases of lumbar central spinal stenosis which are deemed to be compressing a nerve root, the chance for misdiagnosis is fair. (herniated-disc-pain.org)
  • There are a number of potential signs and symptoms of spinal stenosis. (spine-health.com)
  • While spinal stenosis is commonly associated with pain that radiates into the leg or arm, sometimes the pain is felt more locally within the spine, such as in the lower back or neck. (spine-health.com)
  • Depending on the site of occurrence, the signs and symptoms of spinal stenosis can differ. (spine-health.com)
  • Spinal stenosis in the lumbar spine may compress a lumbar spinal nerve(s) and send pain, tingling, numbness, and/or weakness into the leg(s). (spine-health.com)
  • Spinal stenosis is most common in the lumbar spine and cervical spine. (spine-health.com)
  • Spinal stenosis may also occur in multiple places, such as in both the cervical spine and lumbar spine (tandem stenosis). (spine-health.com)
  • While the patient history and physical examination may suggest spinal stenosis, the diagnosis must be confirmed with medical imaging. (spine-health.com)
  • When imaging shows narrowing of the intervertebral foramen and/or vertebral foramen that corresponds with the patient's symptoms, spinal stenosis is diagnosed. (spine-health.com)
  • An MRI is the most common imaging used to diagnose spinal stenosis, but CT with myelography may be used in cases where MRI is not an option. (spine-health.com)
  • Magnetic resonance imaging revealed anterolisthesis at the L4-L5 level and disc protrusions with central and lateral recess spinal stenosis at L3-L4-L5. (thenerve.net)
  • When the spinal cord or nerves become impinged upon by C7, central and/or foraminal stenosis will result, potentially creating a wide diversity of pain and related consequences throughout the body. (spondylolisthesis-pain.com)
  • More severe manifestations of C7 listhesis might require multiple level spinal fusions in order to stabilize the region and resolve any central and/or foraminal stenosis that might be creating neurological compression, as well as mechanical issues that might be painful, as well. (spondylolisthesis-pain.com)
  • Cauda equina syndrome (CES) frequently results from nerve root compression and damage from herniated lumbar discs, spinal stenosis, post-traumatic fractured vertebral fragments, or tumors, which result in devastating morbidity ( 1 ). (iiarjournals.org)
  • Radiography and MRI findings revealed an L3 spinal compression fracture, severe central canal stenosis and right foraminal stenosis at L3-4, and bilateral pedicle screw loosening at L4 ( figure 1A ). (bmj.com)
  • Lumbar laminectomy , represents the standard operative treatment for lumbar spinal stenosis , but this procedure is often combined with fusion surgery. (neurosurgery.directory)
  • Decompression of lumbar spinal stenosis without fusion led to a significant and similar reduction of back pain and leg pain in a short-term and a long-term follow-up group. (neurosurgery.directory)
Symptoms20
  • All remaining six patients who had well-differentiated papillary or follicular thyroid carcinoma were alive at an average of 50 months (range: 17-96 months) after diagnosis and treatment of symptomatic spinal metastases and were ambulant, independent, and able to perform activities of daily living and had no significant pain or neurologic symptoms. (edu.au)
  • They presented with symptoms and signs due to cord compression at the lower thoracic and lumbar vertebrae. (who.int)
  • In my experience as a rheumatologist, it is the nature and severity of neurological symptoms that can influence surgeons' decision-making. (medpagetoday.com)
  • In patients with lower extremity weakness related to a herniated disc, or in patients with signs of myelopathy, timely spine surgery can prevent the progression of spinal cord dysfunction, improve symptoms, and prevent neurologic damage. (medpagetoday.com)
  • When the nerve roots and spinal cord are pressed and damaged, neurological symptoms occur. (epainassist.com)
  • It is called cervical spondylotic muscular atrophy, with the main symptoms being spinal cord dysfunction and muscular weakness in the upper limbs and muscle atrophy, with or without sensory dysfunction. (epainassist.com)
  • In pathologic conditions (eg, abnormalities of the odontoid bone or in the ligaments that keep these joints together), this displacement increases, and bone structures can pressure the spinal cord, producing clinical symptoms. (medscape.com)
  • These symptoms are based on a lack of or insufficient blood flow, which means that the spinal cord can no longer transmit signals from the brain. (medicinelearners.com)
  • Neuroimaging should be considered for achondroplasia patients with neurological symptoms. (biomedcentral.com)
  • The types of symptoms and their severity are dependent on the area of the spinal cord affected. (encyclopedia.com)
  • Symptom criteria include the evolution of symptoms peaking over four hours to 21 days, with symptoms clearly traceable to spinal cord dysfunction, and including muscle weakness or paralysis and sensory defects such as numbness occurring on both sides of the body. (encyclopedia.com)
  • Subjective symptoms are the norm for most herniated disc patients and few demonstrate these objective neurological patterns, despite active diagnoses of pinched nerves. (herniated-disc-pain.org)
  • Symptoms can become worse with flexion of the head, which even further drapes the spinal cord over the upper portion of C2. (uclahealth.org)
  • Surgical treatment is reserved for patients with symptoms refractory to non-operative management, neurological deficit, or severe spinal cord compression. (uclahealth.org)
  • The authors emphasize the importance of considering GBS in patients experiencing deteriorating neurological symptoms after spine surgery and suggest that electrophysiologic studies and CSF analysis are needed for an accurate diagnosis. (thenerve.net)
  • Additionally, this report highlights the need for increased vigilance regarding the rapid onset of GBS symptoms in elderly patients following spinal surgery. (thenerve.net)
  • Right) MRI, T2 Sequence, Axial T2 sequence, demonstrating a central disk herniation causing compression and deformation of the spinal cord, causing symptoms of cervical myelopathy. (medscape.com)
  • While the condition is not very common, more cases of C7 listhesis generate neurological symptoms than any other type of spondylolisthesis, even at lower levels of clinical severity. (spondylolisthesis-pain.com)
  • Minor symptoms can be mitigated using a variety of conservative and symptomatic care methods, such as physical therapy, exercises, massage, TENS and other noninvasive treatments. (spondylolisthesis-pain.com)
  • Any child with a stepwise change in neurological/developmental symptoms or signs should have an MRI with contrast of the brain and spine to look for new CNS melanoma. (medscape.com)
Tumors5
  • A spinal cord infarction occurs much more frequently as a result of blockages in the arteries caused by tumors, aortic aneurysms or aortic dissections. (medicinelearners.com)
  • Spinal cord lipomas are rare lesions, representing less than 1% of all spinal cord tumors. (surgicalneurologyint.com)
  • More common causes are aneurysms of the aorta or ischemia after aortic surgery, compression of vascular structures by tumors, thrombosis or embolism and arterio-venous malformations. (fortunejournals.com)
  • Metastatic tumors and infectious abscesses are not uncommon in the thoracic spine and can result in devastating spinal cord compression. (medmastery.com)
  • Neoplastic CES may arise from cauda equina primary tumors or secondary metastases, which may involve the vertebral bones, resulting in fracture and external nerve compression ( 5 ). (iiarjournals.org)
Vertebral11
  • The nerve root runs about one vertebral body downward from the medullary segment and exits the spinal canal through the foramina. (epainassist.com)
  • The spinal column is of relatively normal length but becomes kyphotic as a result of vertebral anomalies and body habitus. (medscape.com)
  • To date, no case has been described in the literature in which traumatized patients developed vascular myelopathy with a time delay without the presence of direct spinal trauma or direct vertebral vascular injury. (fortunejournals.com)
  • Patients generally become symptomatic when the displaced vertebral segment causes sufficient pressure on the upper spinal cord or lower portion of the brainstem. (uclahealth.org)
  • The spinal cord fills more of the vertebral foramen in the neck than in the lumbar region and so any problem such as a small haematoma is more likely to impinge on the spinal cord. (marlboroughhousetherapycentre.co.uk)
  • 7] ACDF similarly involves removing the symptomatic cervical disc with an added step of placing bone graft to encourage bony fusion of the upper and lower vertebral body. (medscape.com)
  • Significant listhesis at C7 also encourages herniated discs, especially at C7/T1, facet joint pain issues and possible traumatic or compression fracture of aspects of the vertebral bones regionally. (spondylolisthesis-pain.com)
  • The cauda equina is the conglomeration of lumbar and sacral nerve roots distally to the terminal portion of the spinal cord, starting at the L1-L2 vertebral level in most people. (iiarjournals.org)
  • If a vertebral body or a disc lesion compresses the spinal cord, it should be removed with the respective decompression technique. (aofoundation.org)
  • The disc and adjacent endplates are evacuated into the created void followed by the posterior vertebral wall and disc within the spinal canal. (aofoundation.org)
  • Unstable vertebral injuries are those in which bony and ligamentous integrity are disrupted sufficiently that free movement can occur, potentially compressing the spinal cord or its vascular supply and resulting in marked pain and potential worsening of neurologic function. (msdmanuals.com)
Spine23
  • There is a debate about whether this condition represents a focal form of primary LMN degeneration (ie, a focal form of spinal muscular atrophy) or a local consequence of chronic compression from a dural expansion in the cervical spine. (wikipedia.org)
  • Metastatic disease to the spine has the potential to cause severe morbidity, including pain, neurological deficit, and paraplegia. (edu.au)
  • Symptomatic osteoarthritis (OA) of the hip and degenerative lumbar spine disorders can commonly co-exist. (medpagetoday.com)
  • The results showed some patterns of preference shared by both specialties in some scenarios, such as treatment of the hip first when the spinal problem was radicular leg pain and treatment of the spine first with signs of myelopathy, but significantly varied opinions in others, such as weakness in the leg due to a single-level lumbar disc herniation and mechanical back pain from scoliosis. (medpagetoday.com)
  • There appears to be complex interactions between symptomatic OA of the hip and degenerative lumbar spine disorders. (medpagetoday.com)
  • A multi-disciplinary approach for providing personalized care can be very helpful to address whether hip or spine is the predominant pathology and to address controversial topics such as risk of hip dislocations after spinal surgery. (medpagetoday.com)
  • Spinal lipomas are usually extramedullary lesions, and are typically found in the lumbosacral spine with spinal dysraphism. (surgicalneurologyint.com)
  • Injuries of the spine or the spinal chord were not apparent. (fortunejournals.com)
  • Spinal ischemia in traumatized patients is rarely described, and when it occurs, it is usually associated with direct trauma to the spine and consecutive vascular injury. (fortunejournals.com)
  • At the UCLA Health Spine Center, our experts diagnose, manage and treat all spinal injuries and conditions. (uclahealth.org)
  • The reported number of spinal procedures was compared to the ACGME minimum requirements for each surgical category pertaining to adult spine surgery. (thejns.org)
  • The thoracic spine is not a common site for symptomatic degenerative nerve root compression or degenerative spinal cord compression. (medmastery.com)
  • Although less common than in the cervical spine, thoracic spine compression can cause radiculopathy or myelopathy. (medmastery.com)
  • Compression of the thoracic spine can cause radiculopathy or myelopathy. (medmastery.com)
  • When evaluating the thoracic spine, look out for red flags, which are indicators of serious spinal disease. (medmastery.com)
  • With any of these findings, be suspicious of a spinal cord disease above the lumbar spine. (medmastery.com)
  • Listhesis at C7 is statistically the most likely to become symptomatic in the entire spine. (spondylolisthesis-pain.com)
  • C7 is a bad location to suffer listhesis, since the changing curvature of the spine makes a migrated C7 likely to contact the spinal cord and/or spinal nerves. (spondylolisthesis-pain.com)
  • In fact, less significant degrees of displacement might still encroach on these neurological structures compared to elsewhere in the spine. (spondylolisthesis-pain.com)
  • Grade 3 and grade 4 diagnoses are likely to produce some degree of expressed symptomology and these issues might become dire if the spinal cord is compressed or the spine loses structural stability. (spondylolisthesis-pain.com)
  • When patients have a decreased motor grade, difficulty in voiding urine and neurological abnormalities after lumbar spine surgery, conus medullaris syndrome with a possible occurrence of subdural hygroma should be considered. (bmj.com)
  • Spinal subdural hygroma (SSH) refers to excess fluid retention in the subdural space along the spine. (bmj.com)
  • Trauma to the spine may cause injuries involving the spinal cord, vertebrae, or both. (msdmanuals.com)
Acute11
  • Radiotherapy for acute metastatic epidural spinal cord compression (MESCC) involves conventional techniques and dose fractionation schemes, as it needs to be initiated quickly. (hindawi.com)
  • Despite the growing sophistication of radiotherapy techniques such as intensity-modulated radiotherapy (IMRT) and stereotactic body radiotherapy (SBRT) [ 2 , 3 ], conventional methods that use opposed 2 ports are still commonly used to treat acute symptomatic MESCC, probably because treatment must be initiated immediately [ 1 , 3 ]. (hindawi.com)
  • Complete spinal cord injury is the complete sensory and motor loss below the site of spinal cord injury following acute or chronic destruction, compression, or ischemia of the spinal cord. (amboss.com)
  • Initially, this may manifest as spinal shock , which is an acute physiological loss or depression of spinal cord function. (amboss.com)
  • Acute stabilization, a thorough neurological examination , and imaging is required for adequate diagnosis. (amboss.com)
  • These include acute transverse myelitis, spinal cord compression, and various demyelinating disorders. (medicinelearners.com)
  • Continued compression causes a nerve to stop signaling altogether, enacting a lack of sensation, not acute or chronic pain. (herniated-disc-pain.org)
  • Spinal ischemia underlies 6% of acute myelopathies [1]. (fortunejournals.com)
  • In the recently published case report by Haynes et al, intraarticular thrombolysis with tissue plasminogen activator (t-PA) in combination with verapamil and an antiplatelet agent (Eptifibatide) was performed for acute occlusion of the anterior spinal artery in a 52-year-old patient. (fortunejournals.com)
  • Here we characterized the effect of intraspinal grafting of clinical grade human fetal spinal cord-derived neural stem cells (HSSC) on the recovery of neurological function in a rat model of acute lumbar (L3) compression injury. (biomedcentral.com)
  • The burden of acute traumatic spinal cord injury among adults in the United States: an update. (neurosurgery.directory)
Instability4
  • Long construct MIPPSF in MSD did not have increased risk of construct failure and offered effective symptomatic relief, including for MM patients, without introducing a greater risk construct instability. (surgicalneurologyint.com)
  • Some factors such as individual treatment strategy, according to the histology of the primary tumor, plan of treatment strategies carried out in a multidisciplinary manner, risk-benefit of radiotherapy, assessment of the degree of spinal instability, improvement in communication and referral between specialists in oncology showed an increase in the survival of these patients. (bvsalud.org)
  • Four patients underwent surgical decompression and stabilization for spinal metastases causing instability, spinal cord compression, neurological deficit, or intractable pain. (edu.au)
  • Autonomic dysreflexia is a long-term complication from thoracic spinal cord injury , leading to life-threatening episodes with cardiovascular instability. (amboss.com)
Deficit2
  • there was no recurrence and minimal neurological deficit with grade II on the modified McCormick scale. (ijssurgery.com)
  • The prognosis of spinal ischemia depends on the severity of the neurologic deficit that presents at the beginning [5]. (fortunejournals.com)
Myelopathy2
Canal9
Severe5
  • This patient was treated with image-guided 3DCRT (IG-3DCRT) alone using a FIF technique and a unique hypofractionated dose fractionation scheme, which resulted in good tumor control and sufficient cord decompression, which in turn allowed a delayed but gradual improvement in her severe neurological dysfunction. (hindawi.com)
  • Partial debulking of a cervical intramedullary lipoma in a patient who originally presented with a severe quadriparesis resulted in significant neurological improvement. (surgicalneurologyint.com)
  • Magnetic resonance imaging (MRI) showed an intradural, intramedullary mass extending from C5 to T2 (6.2 × 1.3 cm), causing a severe cord compression without spinal dysraphism [ Figure 1 ]. (surgicalneurologyint.com)
  • In severe cases, tendon transfers or bone fusions to hold the limbs in better position or to release a nerve compression . (emedicinehealth.com)
  • Анатомія Spinal cord disorders can cause permanent severe neurologic disability. (msdmanuals.com)
Disorders3
  • Regarding the patients with symptomatic OA of the hip and concomitant lumbar spinal disorders, there are no established guidelines on whether arthroplasty of the hip or spinal surgery needs to be performed first. (medpagetoday.com)
  • Damage to an extravertebral, i.e. supplying, artery or the aorta leads to a spinal cord infarction more frequently than due to intrinsic disorders of the spinal arteries. (medicinelearners.com)
  • Journal of Spinal Disorders and Techniques. (illinois.edu)
Vascular3
  • Spinal vascular involvement associated with vasculitis should also be considered as a cause. (medicinelearners.com)
  • A spinal cord infarction is an emergency and is a complication of various vascular diseases such as aortic aneurysms, arteriosclerosis or others. (medicinelearners.com)
  • None had hepato- japonicum live in the mesenteric vascular somiasis of the spinal cord. (who.int)
Stabilization3
  • This custom construct provided long-term stabilization and neurological improvement over a follow-up duration of 9.5 years. (thejns.org)
  • Surgery usually involves the removal of bone that is causing the compression and stabilization with a fusion. (uclahealth.org)
  • The anterior stabilization is a useful method to relieve pressure on the compromised neurological elements or to provide anterior column support. (aofoundation.org)
Complication5
  • Metastatic epidural spinal cord compression (MESCC) is a common neurological complication of cancer and can have devastating consequences for patients [ 1 - 3 ]. (hindawi.com)
  • As a result, males may be more likely to have extramedullary hematopoiesis and thus more likely to require splenectomy or to develop spinal cord compression, an uncommon but serious complication of paraspinal extramedullary hematopoiesis. (medscape.com)
  • However, subdural hygroma occurrence is a very rare complication after revision spinal fusion surgery. (bmj.com)
  • Although SSH is possible, it is a rare complication of cranial and spinal surgeries. (bmj.com)
  • This case report describes a postoperative complication, especially the case of a patient with conus medullaris syndrome with SSH developed proximal to the area of spinal fusion. (bmj.com)
Radiculopathy2
  • For the diagnosis of cervical spondylosis, it is important to diagnose a high-level disorder based on the symptom of the spinal cord and/or radiculopathy and to judge whether or not the high level generally matches the spinal cord compression seen on the image. (epainassist.com)
  • 9) reviewed 158 patients who underwent epidural spinal injections for low-back pain with or without radiculopathy. (neurosurgery.directory)
Results in lasting neur1
  • Using this cranial vault suspension and fusion technique results in lasting neurological improvement and construct stability. (thejns.org)
Lumbar spinal1
  • Here, the authors describe a 50-year-old male with an aggressive ENB, initially treated with resection and chemotherapy/radiation, who developed multiple thoracic and lumbar spinal metastases. (thejns.org)
Fracture1
  • Osteoporotic bones and degenerative joint disease may increase the risk of cord injury at lower impact velocities due to angulations formed by the degenerated joints, osteophytes impinging on the cord, and brittle bone allowing for easy fracture through critical structures. (msdmanuals.com)
Develop spinal cord compre1
Injuries7
  • See " Evaluation and diagnosis of spinal cord injuries " below. (amboss.com)
  • He also opined that Powell was unable to use her hands and fingers for more than one-third of each day due to nerve problems stemming from her spinal injuries. (justia.com)
  • Spinal cord injury epidemiology is changing as preventative interventions reduce injuries in younger individuals, and there is an increased incidence of incomplete injuries in aging populations. (neurosurgery.directory)
  • Traumatic spinal cord injuries (TSCIs) affect up to 500,000 people worldwide each year, and their high morbidity is associated with substantial individual and societal burden and socioeconomic impact 1) 2) . (neurosurgery.directory)
  • During a typical year, there are about 12,000 spinal cord injuries in the US or 40 cases per million persons per year. (msdmanuals.com)
  • The remainder of spinal cord injuries are attributed to assault (12%), sports (10%), and work-related injuries. (msdmanuals.com)
  • Spinal cord injuries occur when blunt physical force damages the vertebrae, ligaments, or disks of the spinal column, causing bruising, crushing, or tearing of spinal cord tissue, and when the spinal cord is penetrated (eg, by a gunshot or a knife wound). (msdmanuals.com)
Posterior3
  • The anterior horn first flattens, and when it becomes more advanced, it forms a cystic cavity in the ventrolateral part of the posterior chord from the central gray matter such as the anterior horn, intermediary, and dorsal horn. (epainassist.com)
  • A 20-year-old female with HCS and progressive symptomatic BI, initially managed with posterior fossa decompression and occipital to cervical fusion, subsequently required cranial vault expansion due to symptomatic shifting of her cranium secondary to POCS. (thejns.org)
  • Arteriosclerosis or an embolism can restrict the blood supply to the anterior (belly) located anterior spinal artery and the posterior (back) located spinal artery. (medicinelearners.com)
Clinical9
  • This paper describes the clinical manifestations, diagnosis and management of schistosomiasis of the spinal cord in 5 patients attending Shaab and Ibn Khuldoun Hospitals, Khartoum from 1997 to 2007. (who.int)
  • The question of 'hip or spinal surgery first' elicits relatively consistent answers in some clinical scenarios, but remains controversial in others, even for experienced surgeons," the authors wrote. (medpagetoday.com)
  • The patient had no clinical signs of cord compression. (medscape.com)
  • Although ENBs often recur and have an aggressive clinical course, spinal metastases are extremely rare and the underlying molecular mechanisms are poorly understood. (thejns.org)
  • The authors performed targeted exome sequencing on both the resected primary tumor and biopsied spinal metastases, which revealed 12 total variants of unknown clinical significance in genes associated with the PI3K/AKT/mTOR pathway, chromatin remodeling, DNA repair, and cell proliferation. (thejns.org)
  • Extensive experimental and clinical data show that the mechanisms leading to a clinically-defined loss of neurological function after spinal trauma can in general be considered in two categories. (biomedcentral.com)
  • Therefore, when approaching suspected symptomatic thoracic spondylosis, it is important to combine the clinical findings and the radiographic findings before drawing any conclusions. (medmastery.com)
  • Although neurological abnormalities are well established as the most common extracutaneous manifestations of mosaicism in children with multiple CMN, with an incidence ranging from 10% to 33% in clinical studies, [ 3-5 ] the blanket term 'NCM' has been applied to all abnormalities, with no systematic subclassification. (medscape.com)
  • With the advent of magnetic resonance imaging (MRI) and the description of the characteristic signal for melanin, [ 5 , 6 ] the spectrum of described neurological abnormalities has expanded to include congenital and acquired, melanotic and nonmelanotic lesions, with widely varying clinical outcomes ranging from benign quiescent lesions to fatal malignancy. (medscape.com)
Diagnosis3
  • Diagnosis involves meeting specific symptom criteria, as well as demonstrating spinal cord involvement with MRI scanning and examination of cerebrospinal fluid. (encyclopedia.com)
  • The presence of a spinal cord tumor or another condition that is exerting pressure on the spinal cord, vitamin B12 deficiency, or a history of radiation therapy to or cyclophosphamide injection into the spinal cord excludes the possibility of a diagnosis of transverse myelitis. (encyclopedia.com)
  • Early diagnosis and timely intervention are critical to prevent symptom progression and, when feasible, promote neurological recovery ( 3 , 4 ). (iiarjournals.org)
Syringomyelia2
  • Syringomyelia is a disorder of CSF and therefore understanding the pathogenesis of this enigmatic disorder is dependent on understanding CSF flow dynamics, biochemistry and factors that influence its absorption and The majority of CSF is produced by the four choroid plexuses (one in each ventricle of the brain), which circulates through the ventricular system and the subarachnoid spaces of the brain and spinal cord (9, 10). (marysfamilymedicine.org)
  • Other less frequent neurological diagnoses include syringomyelia, nonmalignancy-related hydrocephalus, tumours (including ependymoma, meningioma, astrocytoma, choroid plexus papilloma and pineal germinoma) and malformations such as Dandy-Walker and Arnold-Chiari malformations. (medscape.com)
Abnormalities2
  • Historically, symptomatic CNS abnormalities were considered to carry a poor prognosis, although studies from large centres have suggested a much wider variation in outcome. (medscape.com)
  • Multiple CMN, defined as more than one CMN at birth, can be associated with neurological abnormalities of the central nervous system (CNS), traditionally termed neurocutaneous melanosis (NCM). (medscape.com)
Incidence6
Tumor1
  • SVCS occurs in response to mechanical obstruction of the SVC due to external compression, tumor invasion into the vessel, or internal obstruction. (your-doctor.net)
Surgery11
  • Surgery for MSD patients aims to reduce pain, improve neurological function, and offer stability. (surgicalneurologyint.com)
  • The study was carried out to exhaust the scientific literature regarding surgery associated with radiotherapy in patients suffering from metastatic spinal cord compression and to assist in the decision of oncology physicians and professionals in choosing the best treatment for the patient. (bvsalud.org)
  • The researchers carried out a descriptive study using bibliometric and scientometric methods and found that the combination of surgery with postoperative radiotherapy is effective and more efficient than these alone for the treatment of patients affected by metastatic neurological compression. (bvsalud.org)
  • When surgical treatment is indicated for both, it's uncertain whether arthroplasty of the hip or spinal surgery needs to be performed first. (medpagetoday.com)
  • The hypothesis was that surgeons specializing in [total hip arthroplasty] THA would have different preferences for the sequence of treatment than surgeons specializing in spinal surgery," authors N. Liu, et al. (medpagetoday.com)
  • In this report, the authors present a case of GBS in an elderly patient after spinal fusion surgery and emphasize the importance of evaluating new-onset weakness in such cases. (thenerve.net)
  • While there have been few reported cases of GBS after spinal surgery in elderly patients over 65 years old, this manuscript presents a case report and highlights the significance of evaluating new-onset weakness following spinal fusion surgery in this patient population. (thenerve.net)
  • Spinal fusion surgery is the most commonly performed orthopaedic surgical procedure. (bmj.com)
  • In this situation, immediate imaging investigations and emergency surgery might be necessary to reduce the pressure on the spinal cord. (bmj.com)
  • Some cases of SSH have been reported following spinal decompression surgery. (bmj.com)
  • With decompressive surgery and proactive interventions to improve spinal cord perfusion, early treatment has become more intensive. (neurosurgery.directory)
Metastatic spinal1
  • Metastatic spinal disease (MSD) is the most common type (60%) of bone metastases in cancer patients. (surgicalneurologyint.com)
Nerve root2
  • In most cases, the nerve root is not visualized as being compressed, but the foraminal space is said to be narrowed, which is a normal part of the aging process anyway and is not inherently symptomatic. (herniated-disc-pain.org)
  • When a single nerve root is compressed, left side or right, there will be very predictable neurological outcomes, including true objective numbness and weakness in a specific and defined muscle location or set. (herniated-disc-pain.org)
Nerves2
Central spinal cord1
Metastases4
  • However, to our knowledge, the use of this technique to treat spinal metastases, including MESCC, has not previously been reported. (hindawi.com)
  • SUMMARY: We present a case series of eight consecutive patients with symptomatic spinal metastases due to thyroid carcinoma treated by our multidisciplinary team consisting of spinal surgeons, oncologists, and radiologists, with management of each case determined by our surgical algorithm. (edu.au)
  • The only patient with poorly differentiated thyroid cancer, which was refractory to radioiodine-131 died at 6 months after vertebroplasty procedures for symptomatic spinal metastases. (edu.au)
  • CONCLUSION: The potential for long-term survival of several years following development of spinal metastases should be considered during the counseling and decision-making process for patients with thyroid cancer. (edu.au)
Syrinx2
Foramen magnum2
  • One major problem is spinal cord injury caused by the narrow skull base and foramen magnum. (biomedcentral.com)
  • Therefore when the heart beats and there is increase in volume of intracranial blood, CSF is displaced from the cranial to the spinal subarachnoid space through the foramen magnum thus avoiding a deleterious increase in intracranial pressure. (marysfamilymedicine.org)
Hydrocephalus1
  • Neurological complications include hydrocephalus, Chiari I malformations, and basilar invagination (BI). (thejns.org)
Ischemia8
  • However, its effects and mechanisms in spinal cord ischemia-reperfusion injury have not been fully established. (bvsalud.org)
  • In this study, the mechanisms of polydatin against spinal cord ischemia-reperfusion injury were investigated via network pharmacology, molecular docking and molecular dynamics simulation. (bvsalud.org)
  • METHODS: Spinal cord ischemia-reperfusion injury-related targets were obtained from the GeneCards database, while polydatin-related action targets were obtained from the CTD and SwissTarget databases. (bvsalud.org)
  • Molecular docking showed that polydatin had the highest binding affinity for MAPK3, suggesting that MAPK3 is a key target of polydatin against spinal cord ischemia-reperfusion injury. (bvsalud.org)
  • CONCLUSIONS: Polydatin exerts its effects on spinal cord ischemia-reperfusion injury through multiple targets and pathways. (bvsalud.org)
  • MAPK3 may be a key target of polydatin in spinal cord ischemia-reperfusion injury. (bvsalud.org)
  • It should be borne in mind that certain segments of the spinal cord are particularly susceptible to ischemia due to the sometimes low collateral supply to the anterior spinal artery. (medicinelearners.com)
  • Fibrocartilaginous emboli are described in up to 5.5% of cases for unexplained and sudden onset spinal ischemia [2]. (fortunejournals.com)
Dural sac4
  • It is most commonly believed the condition occurs by asymmetrical compression of the cervical spinal column by the cervical dural sac, especially when the neck is flexed. (wikipedia.org)
  • Researchers, including Hirayama, believe that "forward displacement of the cervical dural sac and compressive flattening of the lower cervical cord during neck flexion" is the contributing factor. (wikipedia.org)
  • Studies consistently note a loss of normal neck curvature (the cervical lordosis) and compression of the cervical chord by the dural sac in forward flexion. (wikipedia.org)
  • The spinal dural sac is distensible, further increasing the compliance of the system and minimising rises in central nervous system pressure (15). (marysfamilymedicine.org)
Anterior4
  • citation needed] The disability originates with impaired functioning of the anterior horn cells of the lower cervical cord (lower neck), but the cause of the decline is not fully understood and is still considered unknown. (wikipedia.org)
  • Anyone who is about to suffer a spinal cord infarction (spinalis anterior syndrome) feels a sudden pain in the back with a ring-shaped radiating tightness. (medicinelearners.com)
  • MRI diagnostic showed an anterior hyperintense area in the region of the anterior spinal cord in the sagittal T2- weight, correspondingly hyperintense areas are often found in the axial layers [4, 5]. (fortunejournals.com)
  • 1, 2] This procedure involved removing the symptomatic disc from an anterior approach without placement of a bone graft. (medscape.com)
Prognosis2
Onset1
  • Yet, we couldn´t find any reported case of a trauma patient, that describes a late onset complete paraplegia of the lower limbs caused by spinal chord ischaemia without a spinal (chord) injury. (fortunejournals.com)
Weakness2
Bone2
  • Background: Macrophages play an important role in regulating the course of spinal tuberculosis within the bone microenvironment. (bvsalud.org)
  • Methods: We established study cohorts for spinal tuberculosis, collected bone marrow blood samples, isolated macrophage exosomes, and performed exosome miRNA sequencing. (bvsalud.org)
Surgical decompression1
Occur3
  • When the spinal cord flattens due to compression, pathological changes occur in the gray matter. (epainassist.com)
  • This condition can occur at virtually any spinal level, affecting the nerve serving a specific and well defined set of muscles on one side of the body. (herniated-disc-pain.org)
  • Much has been made of the potential dangers of spinal manipulation but despite its widespread use, serious complications seldom occur. (marlboroughhousetherapycentre.co.uk)
Occurs1
Infarction6
Abstract1
  • ABSTRACT Schistosomiasis of the spinal cord is an uncommon but potentially curable form of schistosomiasis, if diagnosed and managed early. (who.int)