• GM3 synthase deficiency is characterized by recurrent seizures (epilepsy) and problems with brain development. (medlineplus.gov)
  • Symptomatic epilepsy is defined as seizures resulting from an identifiable cerebral disorder. (medscape.com)
  • Cryptogenic epilepsy consists of seizures that occur without an identifiable cause in a patient with cognitive impairment or with neurologic deficits (eg, Lennox-Gastaut syndrome (LGS), infantile spasms [see the first image below], and myoclonic astatic epilepsy of Doose. (medscape.com)
  • Epilepsy and seizures in chil-dren are commonly related to a deficiency of these elements, as children are often fast oxidiz-ers. (arltma.com)
  • SANTE (Stimulation of the Anterior Nucleus of the Thalamus in Epilepsy) was a multicenter, prospective, randomized, double-blind, parallel groups study intended to evaluate the safety and efficacy of bilateral stimulation of the anterior nucleus of the thalamus (ANT) as adjunctive therapy for the treatment of medically refractory epilepsy, characterized by partial-onset (focal) seizures, with or without secondary generalization. (medtronic.com)
  • During the blinded phase, DBS was shown to significantly reduce patients' most severe seizures, complex partial seizures, and incidence of epilepsy-related injury. (medtronic.com)
  • 3-4%) and incidence of acute symptomatic seizures (approx. (nel.edu)
  • The aim of this article was evaluation of the distribution of acute symptomatic and unprovoked seizures in our patient cohort after the solitary epileptic seizures, as well as determination of particular etiological factors responsible for the occurrence of solitary epileptic seizure. (nel.edu)
  • Epilepsy with focal seizures only was seen in 13 patients and West syndrome in 12 patients, preceded by focal symptomatic epilepsies in six. (thieme-connect.de)
  • One patient had epilepsy with myoclonic-astatic seizures and another multifocal spikes associated with epileptic spasms in clusters. (thieme-connect.de)
  • Seven patients had acute symptomatic seizures, secondary to shunt dysfunction in five and shunt infection in two. (thieme-connect.de)
  • The International League Against Epilepsy's (ILAE) revised classification and terminology of seizures and epilepsies, published in 2010, designates West syndrome as an electroclinical syndrome with onset in infancy, and epileptic spasms as a type of seizure. (medscape.com)
  • The other way I describe my job is: I offer a service to physicians, helping them determine whether their patients have epilepsy, seizures, or brain injury. (aset.org)
  • Canine epilepsy in GSDs simply refers to repeated seizures. (total-german-shepherd.com)
  • Canine epilepsy in GSDs is a chronic condition characterized by recurrent seizures. (total-german-shepherd.com)
  • There are so many different causes of chronic recurrent seizures in German Shepherds that canine epilepsy is not even considered a specific disease or even a single syndrome, but rather a broad and diverse category of disorders. (total-german-shepherd.com)
  • Many other problems such as fainting or dizzy spells can also come and go like seizures and may look similar to canine epilepsy to the untrained eye. (total-german-shepherd.com)
  • Conclusion The high proportion of focal onset seizures and the association with childhood febrile convulsions and motor or cognitive impairment points to a significant burden of acquired epilepsy in this population. (bmj.com)
  • Keeping newborns on antiseizure medication after acute neonatal seizures stopped did not change development outcomes or prevent epilepsy, a comparative effectiveness study showed. (medpagetoday.com)
  • In the field of epilepsy treatment, we are often caught between the proverbial rock and hard place: our seizure medications can cause harm but so can seizures," they noted. (medpagetoday.com)
  • The current study suggests this recommendation should include all neonates with acute symptomatic seizures, even in the setting of an abnormal EEG and neurological examination results. (medpagetoday.com)
  • In their study , Glass and co-authors evaluated 303 neonates with acute symptomatic seizures at nine U.S. Neonatal Seizure Registry centers. (medpagetoday.com)
  • Moreover, DMF treatment even when initiated well after the diagnosis of epilepsy, reduced symptomatic seizures long after the drug was eliminated from the body. (biomedcentral.com)
  • Early-onset epilepsy (focal seizures and/or infantile spasms) is present in 85% of patients. (orpha.net)
  • SDB induces repetitive arousals and sleep fragmentation and may cause symptomatic epileptic seizures or hypoxic encephalopathy. (nel.edu)
  • Epilepsy was associated with increased mortality in people with intellectual disabilities in most studies, particularly in those experiencing recent seizures. (lancs.ac.uk)
  • It is perplexing that, although normally speaking, epileptic syndrome is diagnosed based on the seizure types (myoclonic seizures, atonic seizures or absence are common seizure types of some epileptic syndromes), none of the epileptic syndromes were mentioned in these studies, even if we determined if the epilepsy was normally easy to be controlled by the epilepsy classification. (scirp.org)
  • Determination of the appropriate treatment for canine epilepsy, as well as prognosis for the condition, depends on accurate diagnosis of the type and cause of seizures. (akcchf.org)
  • The likelihood of premature death increases with some types of epilepsy, especially if seizures are not well controlled (2). (cdc.gov)
  • US population-based studies indicate that up to 36% of adults with epilepsy had not seen a neurologist or epileptologist in the past year, and as many as 26% of people with recent seizures did not take medicine to control seizures (7,9,10). (cdc.gov)
  • Healthy People 2020 , a set of national objectives to improve population health in the United States, includes a goal of increasing the proportion of people with epilepsy and uncontrolled seizures who receive appropriate medical care (11). (cdc.gov)
  • Briviact is indicated as an adjunctive therapy in the treatment of partial-onset seizures with or without secondary generalization (spreading to both sides of the brain after the initial seizure) in adult and adolescent patients from 16 years of age with epilepsy. (pharmaceutical-technology.com)
  • Briviact is indicated as an add-on treatment to other medications to treat partial onset seizures in patients age 16 years and older with epilepsy. (pharmaceutical-technology.com)
  • Brivlera (brivaracetam) is indicated as adjunctive therapy in the management of partial-onset seizures in patients 4 years of age and older with epilepsy who are not satisfactorily controlled with conventional therapy. (pharmaceutical-technology.com)
  • OBJECTIVE: To determine whether screening continuous EEG monitoring (cEEG) is associated with greater odds of treatment success for neonatal seizures.METHODS: We included term neonates with acute symptomatic seizures enrolled in the Neonatal Seizure Registry (NSR), a prospective, multicenter cohort of neonates with seizures. (stanford.edu)
  • Epilepsy is a complex disorder affecting the central nervous system and is characterised by spontaneously recurring seizures (SRSs). (lu.se)
  • Objective: Phenotypes caused by de novo SCN1A pathogenic variants are very variable, ranging from severely affected patients with Dravet syndrome to much milder genetic epilepsy febrile seizures plus cases. (uu.nl)
  • Outcomes are frequently unsuccessful, underscoring the critical need to better understand the underlying physiology responsible for seizures in dogs with idiopathic epilepsy, if more effective management is to be achieved. (akcchf.org)
  • Two conditions which can cause issues with baclofen therapy are: Slide 3: Renal Dysfunction Epilepsy: Baclofen at higher doses can reduce the threshold for seizures. (weasner.com)
  • To understand the effect of epilepsy on the autonomic nervous system (ANS), the autonomic functions in patients with epilepsy can be evaluated both during seizures and in their baseline state, also known as the interictal state. (medscape.com)
  • Epileptic seizures are called a seizure disorder or epilepsy. (msdmanuals.com)
  • What causes epileptic seizures is often unknown (called idiopathic epilepsy). (msdmanuals.com)
  • Nearly four fifths of people with epilepsy live in low- and middle-income countries, and most of Seizures are a result of excessive electrical them do not get the treatment they need. (who.int)
  • Depending on which part is affected, greater stigma and higher rates of illness people with epilepsy will have different and death than non-convulsive seizures. (who.int)
  • [ 5 ] Some forms of partial epilepsy involve exclusively focal motor seizures with no alteration of awareness or secondary convulsive seizures. (medscape.com)
  • In patients where optimal control of focal motor seizures is not possible, the issues of pain from the repetitive muscle contraction become more apparent and symptomatic treatment may be appropriate. (medscape.com)
  • These findings support the notion that skills in a critical phase of development are particularly vulnerable following the onset of symptomatic focal epilepsy in childhood. (aston.ac.uk)
  • Prospective, population-based studies were limited to those recruiting only childhood-onset TLE or those reporting TLE as a subgroup of cohorts of focal epilepsies. (hindawi.com)
  • Both focal and generalized idiopathic epilepsies occur in Belgian Shepherds. (sciencedaily.com)
  • More than 2/3 of the patients with CSP showed epilepsy and an abnormal EEG record, however, focal EEG changes were seen more frequently in the group of patients with epilepsy without CSP, than in patients with CSP. (nel.edu)
  • There was no significant difference in the efficacy of the treatment between symptomatic generalised or symptomatic focal syndromes. (nih.gov)
  • Focal epilepsy and epileptic encephalopathies were the most frequent syndromes. (thieme-connect.de)
  • Symptomatic generalized epilepsy (SGE) encompasses a group of challenging epilepsy syndromes. (medscape.com)
  • Specific syndromes of progressive myoclonic epilepsy with key clinical features include Unverricht-Lundborg disease (Baltic myoclonus), myoclonus epilepsy with ragged red fibers (MERRF), neuronal ceroid lipofuscinoses (Batten disease), and sialidoses (cherry-red spot myoclonus syndrome). (medscape.com)
  • Epilepsy syndromes include symptomatic, cryogenic, and idiopathic epilepsy. (medscape.com)
  • EEG characteristics of these specific electroclinical epilepsy syndromes are discussed in this article. (medscape.com)
  • Epilepsy affects about 1-5% of the human population at some stage of live, and it includes a host of syndromes the age of onset, causes and prognosis of which vary significantly. (sciencedaily.com)
  • Based on their basic mechanisms epilepsy syndromes are divided into genetic (idiopathic) epilepsies, structural / metabolic (symptomatic) epilepsies and epilepsies of unknown cause. (sciencedaily.com)
  • We present 67 patients with early-onset shunted hydrocephalus and epilepsy, focusing on the prevalence of epileptic syndromes. (thieme-connect.de)
  • Those with transient reversible seizure causes or neonatal-onset epilepsy syndromes were excluded. (medpagetoday.com)
  • This insufficient supportive evidence stems from the fact that most of the current studies regarding TCHM for epilepsy treatment are not designed according to the different seizure types and epileptic syndromes (STESs). (scirp.org)
  • based on the clinical manifestation and the EEG features, there are different epilepsy types and epileptic syndromes even if the classification system is not perfect. (scirp.org)
  • According to a recent International League Against Epilepsy (ILAE) commission report [ 2 ], the natural history of mTLE-HS is characterized by key features such as a history of an initial precipitating injury and a presence of a latent and/or silent period. (hindawi.com)
  • They defined post-neonatal epilepsy, a secondary outcome, by International League Against Epilepsy criteria , determined by parent interview and medical records. (medpagetoday.com)
  • Epilepsia published by Wiley Periodicals, Inc. on behalf of International League Against Epilepsy. (uu.nl)
  • Children were seen at one of two hospital centres or a residential centre for young people with epilepsy. (nih.gov)
  • Methods We identified 291 people with epilepsy (PWE) in a rural population in Tanzania. (bmj.com)
  • Purpose: Epilepsy is highly prevalent in people with intellectual disabilities and mortality is increased in people with epilepsy generally. (lancs.ac.uk)
  • This review summarises research on the comparative risk of mortality in people with intellectual disabilities and epilepsy compared to the general population, people with intellectual disabilities without epilepsy, and people with epilepsy without intellectual disabilities. (lancs.ac.uk)
  • Thompson AW, Kobau R, Park R, Grant D. Epilepsy care and mental health care for people with epilepsy: California Health Interview Survey, 2005. (cdc.gov)
  • Evidence indicates deficiencies exist in the care received for both epilepsy-related care and for mental health care in people with epilepsy. (cdc.gov)
  • Evidence indicates there are deficiencies in both these areas for people with epilepsy. (cdc.gov)
  • Our objective was to evaluate treatment gaps in epilepsy and mental health care among California adults with epilepsy and to compare the mental health services and treatment received by people with epilepsy to that of the general population. (cdc.gov)
  • The risk for suicide among people with epilepsy is 5 times the rate of the national population, reflecting the burden of untreated mental illness in this population (3-5). (cdc.gov)
  • People with epilepsy require complex care but often face barriers accessing quality treatment, which hinder care and increase health disparities (6-8). (cdc.gov)
  • The risk of premature death in people with epilepsy is up to three times higher than among the general population. (who.int)
  • There is also no consensus on whether all cases of cycticercosis of the central nervous system benefit from cestocidal treatment with its associated sophisticated diagnostic assessment, or whether simple symptomatic treatment with antiepileptic drugs alone can provide them sustained comfort and quality of life. (who.int)
  • These generally respond to time and simple symptomatic treatment. (weasner.com)
  • West syndrome is a severe epilepsy syndrome composed of the triad of infantile spasms, an interictal electroencephalogram ( EEG ) pattern termed hypsarrhythmia, and mental retardation. (medscape.com)
  • Infantile spasms can be classified according to their suspected etiology as symptomatic, cryptogenic, or idiopathic. (medscape.com)
  • Patients are diagnosed with symptomatic infantile spasms if an identifiable factor is responsible for the syndrome. (medscape.com)
  • West syndrome is a severe epilepsy syndrome composed of the triad of infantile spasms, an interictal electroencephalogram ( EEG ) pattern termed hypsarrhythmia, and mental retardation, although the diagnosis can be made even if 1 of the 3 elements is missing (according to the international classification). (medscape.com)
  • Of the 116 patients there were 32 cases (37.12%) of an acute symptomatic seizure and 84 cases (62.88%) of an unprovoked seizure. (nel.edu)
  • The "Natural" History of Medically Treated Temporal Lobe Epilepsy: What Can an Evidence-Based Approach Tell Us? (hindawi.com)
  • We systematically reviewed the literature to describe the "natural" history of medically treated temporal lobe epilepsy (TLE). (hindawi.com)
  • Mesial temporal lobe epilepsy (mTLE) associated with hippocampal sclerosis (mTLE-HS), a condition that can be detected by modern magnetic resonance imaging (MRI) techniques with a high sensitivity and specificity, is now the most common indication for epilepsy surgery. (hindawi.com)
  • Temporal lobe epilepsy (TLE) is a common and commonly devastating form of human epilepsy for which only symptomatic therapy is available. (jneurosci.org)
  • SIGNIFICANCE STATEMENT Temporal lobe epilepsy (TLE) is a common and devastating form of human epilepsy that lacks preventive therapies. (jneurosci.org)
  • Temporal lobe epilepsy (TLE) is a common and commonly devastating form of human epilepsy because of its suboptimal responsiveness to antiseizure medications and frequent psychiatric comorbidities ( French, 2007 ). (jneurosci.org)
  • The effects of DMF in preventing the onset of epilepsy and modifying the disease were investigated in the kainic acid-induced status epilepticus model of temporal lobe epilepsy in rats. (biomedcentral.com)
  • Epileptic patients undergo symptomatic pharmacolog-ical treatments, however, in 30% of cases, they are ineffective, mostly in patients with temporal lobe epilepsy. (lu.se)
  • In adulthood, most patients with symptomatic generalized epilepsy (SGE) have a less well-defined syndrome that still has the characteristics of SGE and is closest to a Lennox-Gastaut syndrome (intractable multiple seizure types, mental retardation, and cerebral palsy). (medscape.com)
  • The term infantile spasm has been used to describe the seizure type, the epilepsy syndrome, or both. (medscape.com)
  • Seizure types and epileptic syndrome of TCMH for epilepsy treatments in a review (Li Q, et al. (scirp.org)
  • Differentiate epilepsy with epileptiform discharges during slow-wave sleep and the Landau-Kleffner syndrome from related conditions. (medscape.org)
  • Type, etiology of epilepsy and actual antiepileptic therapy was recorded. (nel.edu)
  • [ 1 ] In symptomatic generalized epilepsy, an underlying structural or metabolic derangement is also present. (medscape.com)
  • This is a group of epilepsies secondary to metabolic and neurodegenerative conditions. (medscape.com)
  • Several genes affecting the development of symptomatic epilepsies have already been identified, but the genetic background of multifactorial idiopathic epilepsies often remain unknown. (sciencedaily.com)
  • We conclude that therapies targeting TrkB signaling for preventing epilepsy should spare TrkB-Shc-Akt signaling and thereby preserve the neuroprotective benefits. (jneurosci.org)
  • Development and preclinical assessment of novel therapies for Epilepsy. (lu.se)
  • The ketogenic diet has been widely and successfully used to treat children with drug-resistant epilepsy since the 1920s. (nih.gov)
  • Drug-resistant epilepsy occurs in approximately 30% of patients and growing evidence indicates that oxidative stress contributes to the development of such epilepsies. (biomedcentral.com)
  • Strategies to prevent the emergence of drug-resistant epilepsy (DRE) would be of significant value to patients and their healthcare providers. (biomedcentral.com)
  • The clinical use of the new electrodes include application for symptomatic relief of chronic pain and movement disorders such as Parkinson's disease, improving control of prostheses in paralyzed patients and diagnostics in patients suffering from drug resistant epilepsy. (lu.se)
  • Epilepsy, a chronic neurological disorder, affects approximately 2 million Americans and is more common than autism, cerebral palsy, multiple sclerosis, and Parkinson disease combined (1). (cdc.gov)
  • The results from this trial of the ketogenic diet support its use in children with treatment-intractable epilepsy. (nih.gov)
  • Overall, 13% of children developed epilepsy, which was not associated with treatment duration. (medpagetoday.com)
  • This study supports the findings from smaller studies that stopping the antiseizure medicine before a child goes home from the hospital leads to many fewer days of treatment with potentially harmful antiseizure medications like phenobarbital, and that there is no increased risk of epilepsy or developmental issues when the medicine is stopped early," she said. (medpagetoday.com)
  • Activation of the Nrf2 pathway, which is involved in cellular defense, offers a potential strategy for reducing oxidative stress and epilepsy treatment. (biomedcentral.com)
  • Moreover, DMF treatment reversed epilepsy-induced behavioral deficits in the treated rats. (biomedcentral.com)
  • Here, we explore the reasons why many studies have not considered the various STESs and explain how to treat epilepsy according to the pharmacological mechanism for different STESs and exploit the advantage of TCHM for epilepsy treatment. (scirp.org)
  • These complex mixtures have been recognized as effective and safe medicaments for epilepsy treatment, not only for ancient societies but also for contemporary patients, from the mainland to overseas. (scirp.org)
  • However, there is insufficient supportive evidence to certify the effect of TCHM for epilepsy treatment, partly because the studies are not based on epilepsy classifications. (scirp.org)
  • The review reflected two problems: First, none of the studies verified the effect of TCHM for epilepsy treatment according to the epilepsy classification. (scirp.org)
  • The current studies demonstrate that we should attach importance to using TCHM for epilepsy treatment according to the different STESs. (scirp.org)
  • Ongoing studies are exploring the use and effects of dietary supplements in the treatment of canine epilepsy, underlying genetics and disease mechanisms, and the role of the gastrointestinal tract and microbiome in the development and treatment of this disease. (akcchf.org)
  • Adults with epilepsy and psychological distress appeared to have received more mental health treatment than psychologically distressed adults without epilepsy. (cdc.gov)
  • Efforts should be made to improve access to quality epilepsy care that includes assessment and treatment of mental health disorders. (cdc.gov)
  • Brivaracetam is under development for the treatment of childhood absence epilepsy (childhood epilepsy) and juvenile absence epilepsy (Epilepsy). (pharmaceutical-technology.com)
  • Considerations in the treatment of the patient with epilepsy. (doaj.org)
  • Idiopathic epilepsy is the most common chronic neurological disorder of dogs, for which the cause remains poorly understood, and the standard of care is limited to symptomatic treatment with anti-seizure drugs. (akcchf.org)
  • Alterations in RSNs have been documented in humans with epilepsy, and specific changes associated with disease progression, severity, and treatment response. (akcchf.org)
  • In palliative care, patients receiving corticosteroids for symptoms such as fatigue, anorexia, refractory nausea and vomiting or adjuvant analgesia and symptomatic treatment of cord compression or raised intracranial pressure, Dexamethasone phosphate/DEMO may be administered subcutaneously (see section 4.2) as an alternative to the oral route when the latter is unacceptable or no longer feasible. (who.int)
  • Antiviral treatment may be considered on the basis of clinical judgment for hours of illness, if possible, for greatest previously healthy, symptomatic outpatients. (cdc.gov)
  • Genetic factors are estimated to play a role in the development of epilepsy in as many as 40% of epilepsy patients. (sciencedaily.com)
  • Although activation of TrkB signaling promotes development of epilepsy in this context, it also reduces SE-induced neuronal death. (jneurosci.org)
  • In few cases surgical intervention is considered and no treatments interfering with or preventing the development of epilepsy are currently available. (unife.it)
  • Canine epilepsy in GSDs can be caused by a variety of causes. (total-german-shepherd.com)
  • There are many known causes of canine epilepsy. (safehounds.com)
  • This disorder can be inherited as some breeds like the Beagle, Collie, Golden Retriever, Labrador, Keeshund are predisposed to canine epilepsy. (safehounds.com)
  • Canine epilepsy can be idiopathic or primary. (safehounds.com)
  • Canine epilepsy can also be symptomatic or secondary. (safehounds.com)
  • Some canine epilepsy is a consequence of diseases like diabetes, brain tumor, kidney disorders and intoxication from harmful chemicals. (safehounds.com)
  • New studies that translated results from the research lab to the veterinary clinic were sought in 2014 in a collaborative response to donors, dog owners and the veterinary community impacted by canine epilepsy. (akcchf.org)
  • Since 1995, CHF and its donors have invested more than $2.8 million in 42 grants to study canine epilepsy. (akcchf.org)
  • Dr. Diane Brown, former CHF CEO, spoke with Pure Dog Talk in 2018 about canine epilepsy and the multifaceted research approach being taken to address this common malady in dogs through the AKC Canine Health Foundation's Epilepsy Research Initiative. (akcchf.org)
  • It was also under development for postherpetic neuralgia and unverricht lundborg disease (ULD), symptomatic myoclonus and partial seizure. (pharmaceutical-technology.com)
  • A study of social outcomes in a Nova Scotia study found that 20 years after diagnosis of childhood-onset symptomatic generalized epilepsy (SGE), 25% die. (medscape.com)
  • Conclusions: The current antiepileptic therapy is symptomatic and not curative, being necessary to keep in mind the general aspects in the management of the epileptic patient, in an integral and individualized way.Keywords: epilepsy, scientific therapy, antiepileptic drugs. (doaj.org)
  • Camfield P, Camfield C. Long-term prognosis for symptomatic (secondarily) generalized epilepsies: a population-based study. (medscape.com)
  • The prognosis of Epilepsy, as in most diseases, depends on the cause of epilepsy. (ndtv.com)
  • Results: The importance of the positive diagnosis of epilepsy for a correct management of the patient is described. (doaj.org)
  • Developmental cerebral dysplasias are frequent causes of epilepsy. (nel.edu)
  • Symptomatic causes refer to discernible external or structural change, whereas with idiopathic epilepsy there is a strong genetic background. (sciencedaily.com)
  • The condition can be inherited (genetic epilepsy), caused by structural problems in the brain (symptomatic epilepsy), or may be of unknown cause (idiopathic epilepsy). (akcchf.org)
  • Neurologic examination and imaging in the essential idiopathic, typically genetic, epilepsies are usually normal. (medscape.com)
  • Normal background suggests primary epilepsy (ie, idiopathic or possibly genetic epilepsy). (medscape.com)
  • This research opens new avenues for the understanding of the genetic background of the most common canine epilepsies. (sciencedaily.com)
  • The research of Professor Hannes Lohi and his group conducted at the University of Helsinki and the Folkhälsan Research Center opens new avenues for the understanding of the genetic background of the most common canine epilepsies. (sciencedaily.com)
  • A genetic basis for idiopathic epilepsy is strongly suspected in several breeds beside the German Shepherd - including the Beagle, Belgian Tervuren, Keeshond, Dachshund, Labrador Retriever, Golden Retriever and Collie. (total-german-shepherd.com)
  • By comparing the genome of dogs with epilepsy and healthy control dogs a gene region in chromosome 37 was discovered, which if homozygous, increases the risk of epilepsy seven-fold. (sciencedaily.com)
  • In addition to contributing to the clinical presentation, autonomic involvement of organs due to epilepsy can contribute to sudden unexpected death in epilepsy (SUDEP). (medscape.com)
  • In this context, EPIXCHANGE aims at exploring, providing the basis for clinical application and implementing in the industrial arena new and unconventional strategies for the therapy of partial epilepsy advancing the state-of-the-art in the field. (unife.it)
  • The identified genomic region is likely to be the strongest single risk factor for epilepsy in Belgian Shepherds, and we are studying an interesting gene variant causing an amino acid change in the protein level. (sciencedaily.com)
  • Epilepsy was classified according to ILAE criteria. (bmj.com)
  • The patient is suffering from mainly severe residual defects after near-drowning ( n = 5), asphyxia ( n = 4), other hypoxic events ( n = 8) and brain injury ( n = 3) with prolonged disorders of consciousness ( n = 27), pharmacoresistant symptomatic epilepsies ( n = 28), nutritional disturbances with gastric tube feeding ( n = 29) as well as artificial ventilation/tracheostoma ( n = 6). (thieme-connect.com)
  • Epilepsy affects over 65 million people worldwide and significantly burdens patients, caregivers, and society. (biomedcentral.com)
  • Epilepsy affects one in every 100 dogs (Heske L, Nodvedt A, Jaderlund KH, Berendt M, Egenvall A. A cohort study of epilepsy among 665,000 insured dogs: incidence, mortality and survival. (akcchf.org)
  • The most common type of epilepsy, which many as 10% of people worldwide have one affects six out of 10 people with the disorder, is seizure during their lifetime. (who.int)
  • This study explored the impact of developmental stage on cognitive function in children with recently-diagnosed epilepsy. (aston.ac.uk)
  • Nonparametric analyses revealed that skills in a critical developmental period for the group with EO epilepsy fell below normative standards (Phonological Processing: p = .007, Design Copying: p = .01, Visuomotor Precision:, p = .02) and fell below the performance of the group with LO epilepsy (Design Copying: p = .03, Visuomotor Precision: p = .03). (aston.ac.uk)
  • There were no differences between the group with EO epilepsy and the group with LO epilepsy on measures of receptive vocabulary and memory, which were proposed to be in a stable developmental period across both groups. (aston.ac.uk)
  • Developmental cerebral dysplasias, cavum septi pellucidi and epilepsy: clinical, MRI and electrophysiological study. (nel.edu)
  • See what Karen R. Muñana, DVM, MS, DACVIM (Neurology) has to say about the link between epilepsy and gastrointestinal health here . (akcchf.org)
  • The research group of Professor Hannes Lohi, working in collaboration with Danish, Swedish and American researchers in an EU-funded project, has made a major breakthrough by identifying a chromosome region associated with the most common form of epilepsy in dogs. (sciencedaily.com)
  • Most German Shepherds with the idiopathic form of epilepsy suffer their first seizure between the ages of one and five years of age. (total-german-shepherd.com)
  • The type of epilepsy occurring in Belgian Shepherds is extremely common in also other breeds and thus the discovery may have an impact on the understanding of the epilepsies in different dog breeds. (sciencedaily.com)
  • It causes serious morbidity and in areas where T. solium is endemic, is known to be a leading cause of epilepsy, which has profound social, physical and psychological consequences. (who.int)
  • Hence, rs-fMRI has emerged as a powerful tool for investigating the underlying cause of epilepsy in humans and holds similar promise in the study of epilepsy in dogs. (akcchf.org)
  • Hair analysis may possibly provide additional insight and a more permanent solution for many cases of epilepsy. (arltma.com)
  • Toxic metals including cadmium, lead, mer-cury and excessive copper are commonly found in cases of epilepsy. (arltma.com)
  • In summary, diet should never be ignored in cases of epilepsy. (arltma.com)
  • In Ecuador, about 10% of all cases of epilepsy, and 25% of those attributable to a particular identifiable event, were due to cysticercosis of the central nervous system. (who.int)
  • Twenty-seven percent of California adults with epilepsy who had had at least 1 seizure in the past 3 months had not seen a neurologist or epilepsy specialist in the past year. (cdc.gov)
  • California adults with epilepsy appear to have substantial unmet needs in both epilepsy care and mental health care. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) supported questions in the 2005 California Health Interview Survey (CHIS) to examine health services among community-dwelling adults with epilepsy. (cdc.gov)
  • In 2017, an initiative matched-funding challenge furthered CHF's ability to support innovative research leading to better understanding of epilepsy and more effective treatments. (akcchf.org)
  • About 30-40% of the patients are refractory to pharmacological treatments, which are mostly symptomatic and often have side effects. (unife.it)
  • This is in contrast to the cumulative incidence of epilepsy (approx. (nel.edu)
  • Then, we explain how we treat epilepsy using TCHM according to the different STESs and Bian Zheng Lun Zi. (scirp.org)
  • These results provide a strong rationale for a novel therapeutic strategy selectively targeting individual signaling pathways downstream of TrkB for preventing epilepsy. (jneurosci.org)
  • Taken together, these findings suggest that DMF, through the activation of Nrf2, has the potential to serve as a therapeutic target for preventing epileptogenesis and modifying epilepsy. (biomedcentral.com)
  • to review the experience with lamotrigine therapeutic drug monitoring in a tertiary epilepsy centre aiming to characterize the plasma concentrations profile. (bvs.br)