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  • characteristics
  • But a number of other factors, including the child's age and leukemia characteristics, can also affect outlook. (cancer.org)
  • There are several types of leukemia, and each has its own unique set of characteristics, treatment options and outcomes. (moffitt.org)
  • Identification of the specific genetic characteristics of ALL subsets has contributed significantly to more options for precision medicine therapies and is anticipated to improve survival rates in children with Ph-like ALL. (chop.edu)
  • Depending on their characteristics, leukemias can be divided into two broad types. (healthofchildren.com)
  • diseases
  • Age-Adjusted Death Rates per 100,000 450 400 350 300 250 200 150 100 50 0 412 389 379 365 353 322 306 300 288 272 258 245 222 206 192 179 171 US Death Rates Due to Diseases of the Heart* 1980 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012 *Age-adjusted death rates based on Year 2000 US Standard Population. (yumpu.com)
  • The term acute refers to the relatively short time and it is used to differentiate it from the other diseases. (alldiseases.org)
  • Combination Therapy
  • APL patients treated with ATRA/ATO combination therapy demonstrated encouraging long-term survival, particularly in the low-to-intermediate risk group, with good quality of life," the authors concluded. (ashclinicalnews.org)
  • outcomes
  • Survival rates are often based on previous outcomes of large numbers of children who had the disease, but they can't predict what will happen in any child's case. (cancer.org)
  • malignant
  • In the early 1970's, a researchers found that in addition to the necessity to destroy all malignant leukemia cells, mice treated early on had a greater chance of survival. (swaebr.org)
  • Acute lymphocytic leukemia (ALL) is a malignant hematologic disorder resulting from the clonal proliferation of lymphoid precursors with arrested maturation . (springer.com)
  • chromosome
  • Many leukemias involve genetic rearrangements, called translocations, in which some of the genetic material (genes) on a chromosome may be shuffled or swapped between a pair of chromosomes. (adam.com)
  • syndrome
  • Children with Down syndrome have an increased risk of leukemia with a ratio of ALL to AML typical for childhood acute leukemia, except during the first 3 years of life when AML (especially M7) predominates. (meds.com)
  • 10 ] Interestingly, the majority of children with Down syndrome and AML can be cured of their leukemia. (meds.com)
  • A higher incidence of leukemia has also been observed among persons with Down syndrome and some other genetic abnormalities. (healthofchildren.com)